Click here to switch to the map view.

The map label for this gene is ltaE [H]

Identifier: 77461431

GI number: 77461431

Start: 5859212

End: 5860252

Strand: Direct

Name: ltaE [H]

Synonym: Pfl01_5210

Alternate gene names: 77461431

Gene position: 5859212-5860252 (Clockwise)

Preceding gene: 77461422

Following gene: 77461432

Centisome position: 91.0

GC content: 63.69

Gene sequence:

>1041_bases
ATGACCGACAAGAGCCAACAATTCGCCAGCGACAACTACTCCGGTATCTGCCCTGAAGCCTGGGCTGCCATGGAACAGGC
CAACCACGGCCACCAGCGCGCCTATGGCGACGATGAATGGACAGCCCGCGCCTCGGATGATTTCCGTAAGCTGTTCGAGA
CCGACTGCGAAGTGTTCTTCGCCTTCAACGGCACCGCCGCCAACTCGCTGGCGCTGTCGTCGCTGTGCCAGAGTTACCAC
AGCGTGATCTGCTCGGAAACCGCCCACGTCGAAACCGACGAATGCGGCGCGCCGGAATTCTTCTCCAACGGCTCGAAACT
GCTGATCGCCGGCACTGAAAACGGCAAGATCACCCCGGCCTCGATCCGCGAAGTCGCCCTCAAGCGCCAGGACATCCACT
ACCCGAAACCGCGCGTGGTGACGCTGACCCAGGCCACCGAGGTCGGCAGTGTCTACACCCCGGAAGAAGTCCGTGCCATC
AGCGACACCTGCAAGGAACTGGGCCTGAACCTGCACATGGACGGCGCGCGGTTCTCCAACGCCTGCGCCTTCCTCGGCTG
CTCGCCGGCGGATCTGACCTGGAAGGCCGGCGTCGACGTGCTGTGCTTCGGCGGCACGAAAAACGGCATGGCGGTGGGTG
AGGCGATCCTGTTCTTCAACCACAAACTGGCCGAAGACTTCGACTACCGCTGCAAACAGGCCGGGCAACTGGCTTCGAAG
ATGCGTTTCCTGTCGGCGCCGTGGGTCGGCATCCTGGAAAACGACGCCTGGCTCAAATACGCCCGCCACGCCAACCACTG
CGCGCAACTGCTGGCCGAACTGGTCAGCGACATCCCGGGCGTGGAACTGATGTTCCCGGTCCAGGCCAACGGCGTGTTCC
TGCAACTCTCGGAACCGGCCATCGCCGCCCTGACCGCGCGCGGCTGGCGCTTCTACACCTTCATCGGCAAGGGCGGCGCG
CGCTTCATGTGCTCGTGGGACACCGAAGAGGAACGCGTACGCGAACTGGCGCGCGACATCCGCGAAGTCATGTCGGCCTG
A

Upstream 100 bases:

>100_bases
GACAGCGACATCCCGTGTGCTCCCCGGATGATCTTCGGTAAAGTGCGCACCCTCATTGACCAACGGAGCGCCACAAGCGC
ACCGATCACGGAAGCCGGCC

Downstream 100 bases:

>100_bases
TCGCCTCCCCGTGGCGCGGGAGCCTGCTCCCACGCCACAGCTCCTCCCCCTCCTGTTTCAGCTCCATCGTCTACATTGTC
TGTCGAGCCATCGCTCACAT

Product: L-threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTDKSQQFASDNYSGICPEAWAAMEQANHGHQRAYGDDEWTARASDDFRKLFETDCEVFFAFNGTAANSLALSSLCQSYH
SVICSETAHVETDECGAPEFFSNGSKLLIAGTENGKITPASIREVALKRQDIHYPKPRVVTLTQATEVGSVYTPEEVRAI
SDTCKELGLNLHMDGARFSNACAFLGCSPADLTWKAGVDVLCFGGTKNGMAVGEAILFFNHKLAEDFDYRCKQAGQLASK
MRFLSAPWVGILENDAWLKYARHANHCAQLLAELVSDIPGVELMFPVQANGVFLQLSEPAIAALTARGWRFYTFIGKGGA
RFMCSWDTEEERVRELARDIREVMSA

Sequences:

>Translated_346_residues
MTDKSQQFASDNYSGICPEAWAAMEQANHGHQRAYGDDEWTARASDDFRKLFETDCEVFFAFNGTAANSLALSSLCQSYH
SVICSETAHVETDECGAPEFFSNGSKLLIAGTENGKITPASIREVALKRQDIHYPKPRVVTLTQATEVGSVYTPEEVRAI
SDTCKELGLNLHMDGARFSNACAFLGCSPADLTWKAGVDVLCFGGTKNGMAVGEAILFFNHKLAEDFDYRCKQAGQLASK
MRFLSAPWVGILENDAWLKYARHANHCAQLLAELVSDIPGVELMFPVQANGVFLQLSEPAIAALTARGWRFYTFIGKGGA
RFMCSWDTEEERVRELARDIREVMSA
>Mature_345_residues
TDKSQQFASDNYSGICPEAWAAMEQANHGHQRAYGDDEWTARASDDFRKLFETDCEVFFAFNGTAANSLALSSLCQSYHS
VICSETAHVETDECGAPEFFSNGSKLLIAGTENGKITPASIREVALKRQDIHYPKPRVVTLTQATEVGSVYTPEEVRAIS
DTCKELGLNLHMDGARFSNACAFLGCSPADLTWKAGVDVLCFGGTKNGMAVGEAILFFNHKLAEDFDYRCKQAGQLASKM
RFLSAPWVGILENDAWLKYARHANHCAQLLAELVSDIPGVELMFPVQANGVFLQLSEPAIAALTARGWRFYTFIGKGGAR
FMCSWDTEEERVRELARDIREVMSA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=304, Percent_Identity=25, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320789, Length=336, Percent_Identity=25.297619047619, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 38159; Mature: 38028

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKSQQFASDNYSGICPEAWAAMEQANHGHQRAYGDDEWTARASDDFRKLFETDCEVFF
CCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEE
AFNGTAANSLALSSLCQSYHSVICSETAHVETDECGAPEFFSNGSKLLIAGTENGKITPA
EECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCHH
SIREVALKRQDIHYPKPRVVTLTQATEVGSVYTPEEVRAISDTCKELGLNLHMDGARFSN
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCC
ACAFLGCSPADLTWKAGVDVLCFGGTKNGMAVGEAILFFNHKLAEDFDYRCKQAGQLASK
CEEEECCCCCCCEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRFLSAPWVGILENDAWLKYARHANHCAQLLAELVSDIPGVELMFPVQANGVFLQLSEPA
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCC
IAALTARGWRFYTFIGKGGARFMCSWDTEEERVRELARDIREVMSA
EEHHCCCCEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDKSQQFASDNYSGICPEAWAAMEQANHGHQRAYGDDEWTARASDDFRKLFETDCEVFF
CCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEE
AFNGTAANSLALSSLCQSYHSVICSETAHVETDECGAPEFFSNGSKLLIAGTENGKITPA
EECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCHH
SIREVALKRQDIHYPKPRVVTLTQATEVGSVYTPEEVRAISDTCKELGLNLHMDGARFSN
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCC
ACAFLGCSPADLTWKAGVDVLCFGGTKNGMAVGEAILFFNHKLAEDFDYRCKQAGQLASK
CEEEECCCCCCCEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRFLSAPWVGILENDAWLKYARHANHCAQLLAELVSDIPGVELMFPVQANGVFLQLSEPA
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCC
IAALTARGWRFYTFIGKGGARFMCSWDTEEERVRELARDIREVMSA
EEHHCCCCEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]