Click here to switch to the map view.

The map label for this gene is glcB [H]

Identifier: 77461404

GI number: 77461404

Start: 5829193

End: 5831370

Strand: Direct

Name: glcB [H]

Synonym: Pfl01_5183

Alternate gene names: 77461404

Gene position: 5829193-5831370 (Clockwise)

Preceding gene: 77461402

Following gene: 77461406

Centisome position: 90.54

GC content: 62.26

Gene sequence:

>2178_bases
ATGACTGAACACGTTCAAGTCGGTGGCCTGCAGGTCGCCAAAGTCCTGTTCGACTTCGTGAACAACGAAGCCATTCCCGG
TACCGGCCTCACCGCCGACAAATTCTGGGAAGGTGCCGACAAGGTCATTCACGACCTGGCGCCGAAGAACAAAGCCCTAC
TCGCCAAACGCGATGACTTCCAGGCTCGTATCGATGGCTGGCACCAGAGCCGTGCCGGTCAGCCCCACGACGCCGTGGCC
TATAAAGCCTTCCTGCAAGAGATCGGTTATCTGCTGCCAGAAGCGGCTGATTTCCAGGCAACGACGCAAAACGTCGATGA
CGAAATCGCCCGTACCGCCGGCCCGCAACTCGTGGTCCCGGTGATGAACGCCCGCTTCGCCCTCAACGCCTCGAACGCCC
GCTGGGGTTCGCTGTACGACGCCCTGTATGGCACCGACGCCATCAGCGAAGCCGGCGGCGCGGAAAAAGGCAAAGGCTAC
AACAAGGTGCGTGGCGACAAAGTCATCGCCTTCGCCCGTGCGTTCCTCGACGAAGCCGCGCCATTGGCGACCGGCTCCCA
CGTCGATTCCACCGGCTACAAGATCGCTGACGGCAAACTGGTCGTCACCCTCAAGGGCGGCAGCACCAGCGGCCTGCGCA
ACGACGCACAGCTGATCGGCTTCCAGGGCGATGCCAATGCGCCGATTGCGATCCTGCTGAAGAACAACGGCCTGCATTTC
GAAATCCAGATCGACGCCAGCACCCCGGTCGGCCAGACCGATGCCGCCGGCGTCAAAGACATCCTGATGGAAGCGGCGCT
GACCACCATCATGGACTGCGAAGACTCCGTCGCTGCCGTCGATGCCGACGACAAAGTGGTGATCTACCGCAACTGGCTCG
GCCTGATGAAGGGCGATCTGGCGGAATCCGTGTCCAAGGGCGGCCAGACCTTTACCCGCACCATGAACCCGGACCGCACC
TACACCAAGGTCGACGGCAGCGAACTGACCCTGCACGGCCGTTCGCTGTTGTTCGTGCGTAACGTCGGTCACCTGATGAC
CATCGACGCGATCCTCGACAAGCATGGCAACGAAGTGCCGGAAGGCATCCTCGATGGTCTGGTGACTTGCCTCGCGGCGA
TGCACAACCTGAGCGGCAACACTTCGCGCAAGAACACCCGCACCGGTTCCGTGTACATCGTTAAACCGAAAATGCACGGC
CCTGAAGAAGCGGCGTTCACCAACGAGCTGTTCGGTCGCATCGAAGACGTGTTGGGCCTCAAGCGCAACACCCTGAAAGT
CGGGATCATGGACGAGGAACGCCGCACCACGGTCAACCTCAAGGCCTGCATCCAGGCGGCCAGCGAGCGCGTGGTGTTCA
TCAACACCGGTTTCCTCGACCGCACCGGCGACGAAATCCACACCTCCATGGAAGCCGGCCCGATGGTGCGCAAGGCTGAC
ATGAAGGCCGAGAAATGGATCGGCGCCTACGAGAACTGGAACGTCGATATCGGTCTGAGCACCGGCCTGCAGGGTCGTGC
GCAAATCGGTAAAGGCATGTGGGCGATGCCCGACCTGATGGCAGCGATGCTCGAACAGAAAATCGCTCACCCGCTGGCCG
GCGCCAACACTGCCTGGGTTCCGTCGCCGACCGCCGCTGCGCTGCACGCGCTGCACTACCACAAGGTCGACGTGTTCGCC
CGTCAGGCCGAGCTGGCCAAGCGTGCCCGCGCTTCGGTCGATGACATCCTGACCATCCCGCTGGCGGTCAACCCGAACTG
GACCCCGGAGCAGATCAAGAACGAACTGGACAACAATGCCCAGGGCATTCTCGGTTACGTGGTGCGCTGGATCGACCAGG
GCGTGGGTTGCTCGAAGGTGCCGGACATCAACGACGTCGGCCTGATGGAAGACCGTGCGACGCTGCGTATCTCCAGCCAG
CACATCGCCAACTGGCTGCGCCACGGTGTCGTCACCGAAGCGCAAGTGATGGAAAGCCTCAAGCGCATGGCGCCGGTGGT
GGACCGTCAGAATGCCAACGACCCGCTGTACCGTCCGCTGGCCCCGAACTTCGACAGCAACATCGCCTTCCAGGCGGCGG
TCGAACTGGTGATCGAGGGCACCAAACAGCCGAACGGCTACACCGAGCCGGTCCTGCACCGTCGTCGTCGCGAGTTCAAG
GCTGCCAACGGCCTTTAA

Upstream 100 bases:

>100_bases
GCATGTACTGGTCGAGGGGTTTGTGGTTTAAATGGCCAGAGGCTTCATTGTTAAATTGAAGAGCTGAAAAGCGAAATAGC
TGAGCAGAGTGAGGCAAGCA

Downstream 100 bases:

>100_bases
CCTGCGCGGATGCCGGACACGAAAAAGCCCTGATCTTTCGATCAGGGCTTTTTTTGTTTGCGCCGGATTGGCTAGGGCTC
GATCCCCAACTCATGCCTGA

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 725; Mature: 724

Protein sequence:

>725_residues
MTEHVQVGGLQVAKVLFDFVNNEAIPGTGLTADKFWEGADKVIHDLAPKNKALLAKRDDFQARIDGWHQSRAGQPHDAVA
YKAFLQEIGYLLPEAADFQATTQNVDDEIARTAGPQLVVPVMNARFALNASNARWGSLYDALYGTDAISEAGGAEKGKGY
NKVRGDKVIAFARAFLDEAAPLATGSHVDSTGYKIADGKLVVTLKGGSTSGLRNDAQLIGFQGDANAPIAILLKNNGLHF
EIQIDASTPVGQTDAAGVKDILMEAALTTIMDCEDSVAAVDADDKVVIYRNWLGLMKGDLAESVSKGGQTFTRTMNPDRT
YTKVDGSELTLHGRSLLFVRNVGHLMTIDAILDKHGNEVPEGILDGLVTCLAAMHNLSGNTSRKNTRTGSVYIVKPKMHG
PEEAAFTNELFGRIEDVLGLKRNTLKVGIMDEERRTTVNLKACIQAASERVVFINTGFLDRTGDEIHTSMEAGPMVRKAD
MKAEKWIGAYENWNVDIGLSTGLQGRAQIGKGMWAMPDLMAAMLEQKIAHPLAGANTAWVPSPTAAALHALHYHKVDVFA
RQAELAKRARASVDDILTIPLAVNPNWTPEQIKNELDNNAQGILGYVVRWIDQGVGCSKVPDINDVGLMEDRATLRISSQ
HIANWLRHGVVTEAQVMESLKRMAPVVDRQNANDPLYRPLAPNFDSNIAFQAAVELVIEGTKQPNGYTEPVLHRRRREFK
AANGL

Sequences:

>Translated_725_residues
MTEHVQVGGLQVAKVLFDFVNNEAIPGTGLTADKFWEGADKVIHDLAPKNKALLAKRDDFQARIDGWHQSRAGQPHDAVA
YKAFLQEIGYLLPEAADFQATTQNVDDEIARTAGPQLVVPVMNARFALNASNARWGSLYDALYGTDAISEAGGAEKGKGY
NKVRGDKVIAFARAFLDEAAPLATGSHVDSTGYKIADGKLVVTLKGGSTSGLRNDAQLIGFQGDANAPIAILLKNNGLHF
EIQIDASTPVGQTDAAGVKDILMEAALTTIMDCEDSVAAVDADDKVVIYRNWLGLMKGDLAESVSKGGQTFTRTMNPDRT
YTKVDGSELTLHGRSLLFVRNVGHLMTIDAILDKHGNEVPEGILDGLVTCLAAMHNLSGNTSRKNTRTGSVYIVKPKMHG
PEEAAFTNELFGRIEDVLGLKRNTLKVGIMDEERRTTVNLKACIQAASERVVFINTGFLDRTGDEIHTSMEAGPMVRKAD
MKAEKWIGAYENWNVDIGLSTGLQGRAQIGKGMWAMPDLMAAMLEQKIAHPLAGANTAWVPSPTAAALHALHYHKVDVFA
RQAELAKRARASVDDILTIPLAVNPNWTPEQIKNELDNNAQGILGYVVRWIDQGVGCSKVPDINDVGLMEDRATLRISSQ
HIANWLRHGVVTEAQVMESLKRMAPVVDRQNANDPLYRPLAPNFDSNIAFQAAVELVIEGTKQPNGYTEPVLHRRRREFK
AANGL
>Mature_724_residues
TEHVQVGGLQVAKVLFDFVNNEAIPGTGLTADKFWEGADKVIHDLAPKNKALLAKRDDFQARIDGWHQSRAGQPHDAVAY
KAFLQEIGYLLPEAADFQATTQNVDDEIARTAGPQLVVPVMNARFALNASNARWGSLYDALYGTDAISEAGGAEKGKGYN
KVRGDKVIAFARAFLDEAAPLATGSHVDSTGYKIADGKLVVTLKGGSTSGLRNDAQLIGFQGDANAPIAILLKNNGLHFE
IQIDASTPVGQTDAAGVKDILMEAALTTIMDCEDSVAAVDADDKVVIYRNWLGLMKGDLAESVSKGGQTFTRTMNPDRTY
TKVDGSELTLHGRSLLFVRNVGHLMTIDAILDKHGNEVPEGILDGLVTCLAAMHNLSGNTSRKNTRTGSVYIVKPKMHGP
EEAAFTNELFGRIEDVLGLKRNTLKVGIMDEERRTTVNLKACIQAASERVVFINTGFLDRTGDEIHTSMEAGPMVRKADM
KAEKWIGAYENWNVDIGLSTGLQGRAQIGKGMWAMPDLMAAMLEQKIAHPLAGANTAWVPSPTAAALHALHYHKVDVFAR
QAELAKRARASVDDILTIPLAVNPNWTPEQIKNELDNNAQGILGYVVRWIDQGVGCSKVPDINDVGLMEDRATLRISSQH
IANWLRHGVVTEAQVMESLKRMAPVVDRQNANDPLYRPLAPNFDSNIAFQAAVELVIEGTKQPNGYTEPVLHRRRREFKA
ANGL

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=728, Percent_Identity=58.7912087912088, Blast_Score=892, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 78849; Mature: 78718

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEHVQVGGLQVAKVLFDFVNNEAIPGTGLTADKFWEGADKVIHDLAPKNKALLAKRDDF
CCCCEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCH
QARIDGWHQSRAGQPHDAVAYKAFLQEIGYLLPEAADFQATTQNVDDEIARTAGPQLVVP
HHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHCCCEEEEE
VMNARFALNASNARWGSLYDALYGTDAISEAGGAEKGKGYNKVRGDKVIAFARAFLDEAA
ECCCEEEEECCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
PLATGSHVDSTGYKIADGKLVVTLKGGSTSGLRNDAQLIGFQGDANAPIAILLKNNGLHF
CCCCCCCCCCCCCEEECCEEEEEECCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCEEE
EIQIDASTPVGQTDAAGVKDILMEAALTTIMDCEDSVAAVDADDKVVIYRNWLGLMKGDL
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECHHHHHHHHH
AESVSKGGQTFTRTMNPDRTYTKVDGSELTLHGRSLLFVRNVGHLMTIDAILDKHGNEVP
HHHHHCCCCEEEECCCCCCCEEEECCCEEEEECCEEEEEECCCCHHHHHHHHHHCCCCCH
EGILDGLVTCLAAMHNLSGNTSRKNTRTGSVYIVKPKMHGPEEAAFTNELFGRIEDVLGL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC
KRNTLKVGIMDEERRTTVNLKACIQAASERVVFINTGFLDRTGDEIHTSMEAGPMVRKAD
CCCEEEEEEECCCCHHEEHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCCCHHHHC
MKAEKWIGAYENWNVDIGLSTGLQGRAQIGKGMWAMPDLMAAMLEQKIAHPLAGANTAWV
CCHHHHCCCCCCCCEEEEECCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
PSPTAAALHALHYHKVDVFARQAELAKRARASVDDILTIPLAVNPNWTPEQIKNELDNNA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCH
QGILGYVVRWIDQGVGCSKVPDINDVGLMEDRATLRISSQHIANWLRHGVVTEAQVMESL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHHHH
KRMAPVVDRQNANDPLYRPLAPNFDSNIAFQAAVELVIEGTKQPNGYTEPVLHRRRREFK
HHHCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AANGL
HCCCC
>Mature Secondary Structure 
TEHVQVGGLQVAKVLFDFVNNEAIPGTGLTADKFWEGADKVIHDLAPKNKALLAKRDDF
CCCEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCH
QARIDGWHQSRAGQPHDAVAYKAFLQEIGYLLPEAADFQATTQNVDDEIARTAGPQLVVP
HHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHCCCEEEEE
VMNARFALNASNARWGSLYDALYGTDAISEAGGAEKGKGYNKVRGDKVIAFARAFLDEAA
ECCCEEEEECCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
PLATGSHVDSTGYKIADGKLVVTLKGGSTSGLRNDAQLIGFQGDANAPIAILLKNNGLHF
CCCCCCCCCCCCCEEECCEEEEEECCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCEEE
EIQIDASTPVGQTDAAGVKDILMEAALTTIMDCEDSVAAVDADDKVVIYRNWLGLMKGDL
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECHHHHHHHHH
AESVSKGGQTFTRTMNPDRTYTKVDGSELTLHGRSLLFVRNVGHLMTIDAILDKHGNEVP
HHHHHCCCCEEEECCCCCCCEEEECCCEEEEECCEEEEEECCCCHHHHHHHHHHCCCCCH
EGILDGLVTCLAAMHNLSGNTSRKNTRTGSVYIVKPKMHGPEEAAFTNELFGRIEDVLGL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC
KRNTLKVGIMDEERRTTVNLKACIQAASERVVFINTGFLDRTGDEIHTSMEAGPMVRKAD
CCCEEEEEEECCCCHHEEHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCCCHHHHC
MKAEKWIGAYENWNVDIGLSTGLQGRAQIGKGMWAMPDLMAAMLEQKIAHPLAGANTAWV
CCHHHHCCCCCCCCEEEEECCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
PSPTAAALHALHYHKVDVFARQAELAKRARASVDDILTIPLAVNPNWTPEQIKNELDNNA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCH
QGILGYVVRWIDQGVGCSKVPDINDVGLMEDRATLRISSQHIANWLRHGVVTEAQVMESL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHHHH
KRMAPVVDRQNANDPLYRPLAPNFDSNIAFQAAVELVIEGTKQPNGYTEPVLHRRRREFK
HHHCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AANGL
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA