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The map label for this gene is mrdB [H]

Identifier: 77461190

GI number: 77461190

Start: 5596958

End: 5598100

Strand: Reverse

Name: mrdB [H]

Synonym: Pfl01_4969

Alternate gene names: 77461190

Gene position: 5598100-5596958 (Counterclockwise)

Preceding gene: 77461191

Following gene: 77461189

Centisome position: 86.95

GC content: 59.76

Gene sequence:

>1143_bases
ATGAATAATTTCGATCGCATGCTCTCCAGCGAGGATGTGATGCGTCGCCGGGCGACGCTGTTGCAACGTCTGCATATCGA
CGGCCCGTTGCTGGTGCTGTTGTTGATTCTCGCGGCCGGCAGCCTGTTCGTGCTGTATTCGGCCAGCGGCAAGAGCTGGG
ACTTGCTGGCCAAACAGGCCACATCGTTTGGCATCGGTCTGGTGTCGATGATCGTCATCGCCCAGTTCGAGCCAAGGTTC
ATGGCGCGCTGGGTGCCGCTCGGCTACGTGATCGGCGTGGTGTTGCTGATGGTGGTGGACATCATGGGCCACAACGCAAT
GGGTGCGACCCGCTGGATCAACATCCCCGGGGTGATTCGCTTCCAGCCCTCGGAATTCATGAAGATCCTGATGCCGGCGA
CCATCGCCTGGTACCTGTCCAAACGTACGCTGCCGCCGCAGCTCAAACACGTCGGTATCAGTCTGCTGCTGATCGGTGTG
CCGTTCGCCCTGATCGTGCGTCAGCCGGATCTCGGCACTTCGCTGCTGATTCTGGCCGGCGGCGCCTTCGTGCTGTTCAT
GGGTGGATTGCGCTGGCGCTGGATTCTCAGCGTGCTGGCGGCGGCGATTCCGGTGTCGGTTGCGATGTGGTTCTTCATCA
TGCACGACTACCAGAAACAGCGGATCCTGACGTTCCTCGACCCGGAAAGCGATCCGTTGGGCACCGGCTGGAACATCATC
CAGTCGAAAGCCGCCATCGGTTCCGGCGGCGTGTTCGGCAAGGGCTGGCTGCTGGGAACCCAGTCGCACCTGGACTTCCT
GCCGGAAAGCCACACCGACTTCATCATCGCCGTGCTCGGCGAAGAGTTCGGCCTGGTGGGTATCTGCGCGCTGTTGCTGA
TCTATCTGTTGCTGATCGGTCGTGGCCTGGTGATTACCGCCCAGGCGCAAACGCTGTTCGGCAAACTGTTGGCTGGCGCA
CTGACCATGACGTTTTTTGTTTATGTTTTCGTCAACATCGGTATGGTCAGTGGCCTGTTGCCGGTGGTGGGGGTGCCGTT
GCCGTTCATTAGCTACGGCGGAACTTCGCTGGTGACGCTGCTGTCAGCGTTTGGGGTTTTGATGTCGATCCATACCCATC
GCAAGTGGATCGCACAGGTTTGA

Upstream 100 bases:

>100_bases
CCGGTGGTGCGGCAGGTCATGGATGCCTGGCTGCTGGATCAGGACGGACGGTTGAAGGCCGAATACGCCAGCCCTATCAG
TGCGGAGGCTACGGCCCGTG

Downstream 100 bases:

>100_bases
ATAAGGTGAAGAGTTCAATGCAAGTAATGCGTGACTGGGCGACACGATACGCACCGTGGCTCGGCCTGGTAGGCATCCTT
GGCAGCGTGCAGGAAGCGTT

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MNNFDRMLSSEDVMRRRATLLQRLHIDGPLLVLLLILAAGSLFVLYSASGKSWDLLAKQATSFGIGLVSMIVIAQFEPRF
MARWVPLGYVIGVVLLMVVDIMGHNAMGATRWINIPGVIRFQPSEFMKILMPATIAWYLSKRTLPPQLKHVGISLLLIGV
PFALIVRQPDLGTSLLILAGGAFVLFMGGLRWRWILSVLAAAIPVSVAMWFFIMHDYQKQRILTFLDPESDPLGTGWNII
QSKAAIGSGGVFGKGWLLGTQSHLDFLPESHTDFIIAVLGEEFGLVGICALLLIYLLLIGRGLVITAQAQTLFGKLLAGA
LTMTFFVYVFVNIGMVSGLLPVVGVPLPFISYGGTSLVTLLSAFGVLMSIHTHRKWIAQV

Sequences:

>Translated_380_residues
MNNFDRMLSSEDVMRRRATLLQRLHIDGPLLVLLLILAAGSLFVLYSASGKSWDLLAKQATSFGIGLVSMIVIAQFEPRF
MARWVPLGYVIGVVLLMVVDIMGHNAMGATRWINIPGVIRFQPSEFMKILMPATIAWYLSKRTLPPQLKHVGISLLLIGV
PFALIVRQPDLGTSLLILAGGAFVLFMGGLRWRWILSVLAAAIPVSVAMWFFIMHDYQKQRILTFLDPESDPLGTGWNII
QSKAAIGSGGVFGKGWLLGTQSHLDFLPESHTDFIIAVLGEEFGLVGICALLLIYLLLIGRGLVITAQAQTLFGKLLAGA
LTMTFFVYVFVNIGMVSGLLPVVGVPLPFISYGGTSLVTLLSAFGVLMSIHTHRKWIAQV
>Mature_380_residues
MNNFDRMLSSEDVMRRRATLLQRLHIDGPLLVLLLILAAGSLFVLYSASGKSWDLLAKQATSFGIGLVSMIVIAQFEPRF
MARWVPLGYVIGVVLLMVVDIMGHNAMGATRWINIPGVIRFQPSEFMKILMPATIAWYLSKRTLPPQLKHVGISLLLIGV
PFALIVRQPDLGTSLLILAGGAFVLFMGGLRWRWILSVLAAAIPVSVAMWFFIMHDYQKQRILTFLDPESDPLGTGWNII
QSKAAIGSGGVFGKGWLLGTQSHLDFLPESHTDFIIAVLGEEFGLVGICALLLIYLLLIGRGLVITAQAQTLFGKLLAGA
LTMTFFVYVFVNIGMVSGLLPVVGVPLPFISYGGTSLVTLLSAFGVLMSIHTHRKWIAQV

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=367, Percent_Identity=53.4059945504087, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1786277, Length=293, Percent_Identity=33.7883959044369, Blast_Score=150, Evalue=9e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41606; Mature: 41606

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFDRMLSSEDVMRRRATLLQRLHIDGPLLVLLLILAAGSLFVLYSASGKSWDLLAKQA
CCCHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
TSFGIGLVSMIVIAQFEPRFMARWVPLGYVIGVVLLMVVDIMGHNAMGATRWINIPGVIR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEE
FQPSEFMKILMPATIAWYLSKRTLPPQLKHVGISLLLIGVPFALIVRQPDLGTSLLILAG
ECHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHEEEECCCCCCEEHHHHC
GAFVLFMGGLRWRWILSVLAAAIPVSVAMWFFIMHDYQKQRILTFLDPESDPLGTGWNII
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHH
QSKAAIGSGGVFGKGWLLGTQSHLDFLPESHTDFIIAVLGEEFGLVGICALLLIYLLLIG
HHHHCCCCCCCCCCCEEEECHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHC
RGLVITAQAQTLFGKLLAGALTMTFFVYVFVNIGMVSGLLPVVGVPLPFISYGGTSLVTL
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHH
LSAFGVLMSIHTHRKWIAQV
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNFDRMLSSEDVMRRRATLLQRLHIDGPLLVLLLILAAGSLFVLYSASGKSWDLLAKQA
CCCHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
TSFGIGLVSMIVIAQFEPRFMARWVPLGYVIGVVLLMVVDIMGHNAMGATRWINIPGVIR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEE
FQPSEFMKILMPATIAWYLSKRTLPPQLKHVGISLLLIGVPFALIVRQPDLGTSLLILAG
ECHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHEEEECCCCCCEEHHHHC
GAFVLFMGGLRWRWILSVLAAAIPVSVAMWFFIMHDYQKQRILTFLDPESDPLGTGWNII
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHH
QSKAAIGSGGVFGKGWLLGTQSHLDFLPESHTDFIIAVLGEEFGLVGICALLLIYLLLIG
HHHHCCCCCCCCCCCEEEECHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHC
RGLVITAQAQTLFGKLLAGALTMTFFVYVFVNIGMVSGLLPVVGVPLPFISYGGTSLVTL
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHH
LSAFGVLMSIHTHRKWIAQV
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]