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The map label for this gene is lnt [H]

Identifier: 77461175

GI number: 77461175

Start: 5581292

End: 5582815

Strand: Direct

Name: lnt [H]

Synonym: Pfl01_4954

Alternate gene names: 77461175

Gene position: 5581292-5582815 (Clockwise)

Preceding gene: 77461174

Following gene: 77461178

Centisome position: 86.69

GC content: 64.3

Gene sequence:

>1524_bases
ATGCGCTGGACAACCCGTCCCGGCTGGCCCGGTAACCTGCTGGCCGTGGCGGCCGGTGCAATCACCACCTTCGCGCTGGC
ACCGTTCGATCTCTGGCCGCTGGCCTTGCTGGCAGTCGGCCTGTTCTATGCAGGCCTGCGCGAGCTGAGCCCGCGTCAGG
CCTTGGGTCGTGGCTGGTGCTTCGGCTTCGGCCTGTTCGGCGCCGGCACCAGCTGGATCTATTACAGCATCCACCATTTC
GGCGGCGCTTCGGTGCTGCTGGCCGGTTTCCTGATGCTGATCTTCACGGCGGCGATTGCCTGGTTCTTCGCCCTGCCCGC
CTGGCTGTGGGCACGCTGGTTGCGGCGTAACGACGCGCCGGTGGCTGACGCACTGGCGTTTGCGGCGCTGTGGGTCGGCC
AGGAAGCTTTCCGTGGCTGGTTCCTCACCGGTTTCCCGTGGCTGTATTCCGGGTACAGCCAGCTTGACGGCCCACTGGCC
GGACTCGCGCCAGTGGGCGGGATGTGGCTGGTGTCGTTCGTTCTCGCGCTGACCGCTGCACTGATCTACAACGCACCGCG
CCTGCTGCAAACCCGCCGCAAAGCCTTCATCGCTGCCGGCCTGGTATTGCTGATCGGTCCATGGGCGGCAGGCATTGCGC
TCAAGGGCCATGCCTGGACCAGCCCGGCCGGCGCGCCTCTCACCGTTGCCGCCATCCAGGGCAACGTCGCGCAAAGCATG
AAATGGGACCCGGCCGAGCTCAACGCGCAACTGGCGCTGTACCGCGACCTGAGTTTCCGCTCCAAACCGGTGGACCTGCT
GATCTGGCCGGAAACCGCAGTCCCGGTGCTCAAGGAGTCCGCCGAGGGCTACCTGACCATGATGGGCAACTTCGCCGCCG
AGCGTAAATCGGCGCTGATTACCGGCGTGCCGATCCGCGAAATGGTCCGTCACGAAAAACGCTTCTTCAACGGCATCACC
GTGGTCGGCGAAGGCGATGGCACTTATCTGAAACAGAAGCTGGTGCCATTCGGCGAGTACGTACCCTTGCAGGACATCCT
GCGCGGGCTGATCGCGTTCTTCGACCTGCCAATGTCCGACTTCGCCCGCGGCCCTGCCGATCAGGCCCTGTTGCAGGCCA
AGGGATATCAGATCGCGCCGTTCATCTGCTACGAAGTGGTGTATCCGGAATTCGCCGCAGGCCTGGCGGCACGCAGCGAT
CTGCTGCTGACGATCAGCAACGACACCTGGTTCGGTACGTCGATCGGCCCGCTGCAACACCTGCAAATGGCGCAGATGCG
CGCGCTTGAAGCCGGACGCTGGATGATTCGCGCGACCAACAACGGCGTGACCGGGCTGATCAACCCGTTTGGCCAGATCA
CCGAGCGAATTCCGCAGTTCGAGCAGGGCGTGCTCTACGGCGAAGTGGTGCCGATGCACAACCTGACGCCGTATCTGCAA
TGGCGCTCGTGGCCGCTGATCATCCTGTGTGTGGTGCTGTTCGGCTGGGCGCTGATGACCAACCGGATGTCCAAGACGCT
CTGA

Upstream 100 bases:

>100_bases
AAATCGGCGCCTATCGTTTCCGCATCCTGAACGCCGACAGCCGTCGGATTCATTTGCTGCGACTGACCCCAATCGCCCGG
TAAAAAATCTAAGGATTGAA

Downstream 100 bases:

>100_bases
AAACCCGCTCACTCCCGCGTTCTGCGCGGGAGTGATCAATCGGCGCTGTCACCCCCTCGGTAGAACAGTGAATAGCCGAT
CTGCCCCACCGCCTCGTTCA

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MRWTTRPGWPGNLLAVAAGAITTFALAPFDLWPLALLAVGLFYAGLRELSPRQALGRGWCFGFGLFGAGTSWIYYSIHHF
GGASVLLAGFLMLIFTAAIAWFFALPAWLWARWLRRNDAPVADALAFAALWVGQEAFRGWFLTGFPWLYSGYSQLDGPLA
GLAPVGGMWLVSFVLALTAALIYNAPRLLQTRRKAFIAAGLVLLIGPWAAGIALKGHAWTSPAGAPLTVAAIQGNVAQSM
KWDPAELNAQLALYRDLSFRSKPVDLLIWPETAVPVLKESAEGYLTMMGNFAAERKSALITGVPIREMVRHEKRFFNGIT
VVGEGDGTYLKQKLVPFGEYVPLQDILRGLIAFFDLPMSDFARGPADQALLQAKGYQIAPFICYEVVYPEFAAGLAARSD
LLLTISNDTWFGTSIGPLQHLQMAQMRALEAGRWMIRATNNGVTGLINPFGQITERIPQFEQGVLYGEVVPMHNLTPYLQ
WRSWPLIILCVVLFGWALMTNRMSKTL

Sequences:

>Translated_507_residues
MRWTTRPGWPGNLLAVAAGAITTFALAPFDLWPLALLAVGLFYAGLRELSPRQALGRGWCFGFGLFGAGTSWIYYSIHHF
GGASVLLAGFLMLIFTAAIAWFFALPAWLWARWLRRNDAPVADALAFAALWVGQEAFRGWFLTGFPWLYSGYSQLDGPLA
GLAPVGGMWLVSFVLALTAALIYNAPRLLQTRRKAFIAAGLVLLIGPWAAGIALKGHAWTSPAGAPLTVAAIQGNVAQSM
KWDPAELNAQLALYRDLSFRSKPVDLLIWPETAVPVLKESAEGYLTMMGNFAAERKSALITGVPIREMVRHEKRFFNGIT
VVGEGDGTYLKQKLVPFGEYVPLQDILRGLIAFFDLPMSDFARGPADQALLQAKGYQIAPFICYEVVYPEFAAGLAARSD
LLLTISNDTWFGTSIGPLQHLQMAQMRALEAGRWMIRATNNGVTGLINPFGQITERIPQFEQGVLYGEVVPMHNLTPYLQ
WRSWPLIILCVVLFGWALMTNRMSKTL
>Mature_507_residues
MRWTTRPGWPGNLLAVAAGAITTFALAPFDLWPLALLAVGLFYAGLRELSPRQALGRGWCFGFGLFGAGTSWIYYSIHHF
GGASVLLAGFLMLIFTAAIAWFFALPAWLWARWLRRNDAPVADALAFAALWVGQEAFRGWFLTGFPWLYSGYSQLDGPLA
GLAPVGGMWLVSFVLALTAALIYNAPRLLQTRRKAFIAAGLVLLIGPWAAGIALKGHAWTSPAGAPLTVAAIQGNVAQSM
KWDPAELNAQLALYRDLSFRSKPVDLLIWPETAVPVLKESAEGYLTMMGNFAAERKSALITGVPIREMVRHEKRFFNGIT
VVGEGDGTYLKQKLVPFGEYVPLQDILRGLIAFFDLPMSDFARGPADQALLQAKGYQIAPFICYEVVYPEFAAGLAARSD
LLLTISNDTWFGTSIGPLQHLQMAQMRALEAGRWMIRATNNGVTGLINPFGQITERIPQFEQGVLYGEVVPMHNLTPYLQ
WRSWPLIILCVVLFGWALMTNRMSKTL

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=516, Percent_Identity=39.5348837209302, Blast_Score=322, Evalue=4e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 55835; Mature: 55835

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWTTRPGWPGNLLAVAAGAITTFALAPFDLWPLALLAVGLFYAGLRELSPRQALGRGWC
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHH
FGFGLFGAGTSWIYYSIHHFGGASVLLAGFLMLIFTAAIAWFFALPAWLWARWLRRNDAP
HHHHHHCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VADALAFAALWVGQEAFRGWFLTGFPWLYSGYSQLDGPLAGLAPVGGMWLVSFVLALTAA
HHHHHHHHHHHHCHHHHCCEEHCCCHHHHCCHHHCCCCHHCCCCCCHHHHHHHHHHHHHH
LIYNAPRLLQTRRKAFIAAGLVLLIGPWAAGIALKGHAWTSPAGAPLTVAAIQGNVAQSM
HHHCCHHHHHHHHHHHHHHHHHHHCCCHHHCEEEECCCCCCCCCCCEEEEEECCCHHHCC
KWDPAELNAQLALYRDLSFRSKPVDLLIWPETAVPVLKESAEGYLTMMGNFAAERKSALI
CCCHHHCCCEEEEEECCCCCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHCCEE
TGVPIREMVRHEKRFFNGITVVGEGDGTYLKQKLVPFGEYVPLQDILRGLIAFFDLPMSD
ECCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHH
FARGPADQALLQAKGYQIAPFICYEVVYPEFAAGLAARSDLLLTISNDTWFGTSIGPLQH
HCCCCHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEECCCCCHHHH
LQMAQMRALEAGRWMIRATNNGVTGLINPFGQITERIPQFEQGVLYGEVVPMHNLTPYLQ
HHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHCCHHHCCCEEECEECCCCCCHHHH
WRSWPLIILCVVLFGWALMTNRMSKTL
CCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRWTTRPGWPGNLLAVAAGAITTFALAPFDLWPLALLAVGLFYAGLRELSPRQALGRGWC
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHH
FGFGLFGAGTSWIYYSIHHFGGASVLLAGFLMLIFTAAIAWFFALPAWLWARWLRRNDAP
HHHHHHCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VADALAFAALWVGQEAFRGWFLTGFPWLYSGYSQLDGPLAGLAPVGGMWLVSFVLALTAA
HHHHHHHHHHHHCHHHHCCEEHCCCHHHHCCHHHCCCCHHCCCCCCHHHHHHHHHHHHHH
LIYNAPRLLQTRRKAFIAAGLVLLIGPWAAGIALKGHAWTSPAGAPLTVAAIQGNVAQSM
HHHCCHHHHHHHHHHHHHHHHHHHCCCHHHCEEEECCCCCCCCCCCEEEEEECCCHHHCC
KWDPAELNAQLALYRDLSFRSKPVDLLIWPETAVPVLKESAEGYLTMMGNFAAERKSALI
CCCHHHCCCEEEEEECCCCCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHCCEE
TGVPIREMVRHEKRFFNGITVVGEGDGTYLKQKLVPFGEYVPLQDILRGLIAFFDLPMSD
ECCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHH
FARGPADQALLQAKGYQIAPFICYEVVYPEFAAGLAARSDLLLTISNDTWFGTSIGPLQH
HCCCCHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEECCCCCHHHH
LQMAQMRALEAGRWMIRATNNGVTGLINPFGQITERIPQFEQGVLYGEVVPMHNLTPYLQ
HHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHCCHHHCCCEEECEECCCCCCHHHH
WRSWPLIILCVVLFGWALMTNRMSKTL
CCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]