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The map label for this gene is corC [H]

Identifier: 77461174

GI number: 77461174

Start: 5580435

End: 5581274

Strand: Direct

Name: corC [H]

Synonym: Pfl01_4953

Alternate gene names: 77461174

Gene position: 5580435-5581274 (Clockwise)

Preceding gene: 77461173

Following gene: 77461175

Centisome position: 86.67

GC content: 60.0

Gene sequence:

>840_bases
ATGAGCGAAGATCGATCGAGCAACGGGCAAAAGTCATGGCTGGGTAAACTGACCCAGGCTTTTGCCCACGAGCCGAAGAA
CCGCCAGGAGCTGCTTGAGCTGCTGCGCGATGCACATCAGAACAAACTGCTGGACAGCGAAGCGCTGGCCATCGTCGAAG
GCGCCATCCAGGTGGCTGACCTGCAGGTTCGCGACATCATGGTGCCGCGCTCGCAGATGATCAGCATCAAGGCGACCCAG
ACACCCCGCGAATTCCTCCCCGCCGTGGTCGACTCGGCCCACTCGCGCTACCCGGTCATCGGCGAAAGCCATGACGACGT
GATGGGCGTGCTGCTGGCCAAGGATCTGCTGCCGCTGATCCTCAAGGAGAACGGCGACAGCTTCAACATCAAGGACCTGC
TGCGCCCGGCCACGTTCGTGCCGGAGTCCAAGCGTCTGAACGTGTTGCTGCGTGAATTCCGCGCCAACCACAACCACATG
GCCATCGTGATCGACGAATACGGTGGTGTGGCCGGTCTGGTGACCATCGAAGACGTGCTCGAGCAGATCGTCGGCGACAT
CGAAGACGAGCACGACGTCGAAGAAGACAGCTACATCAAGCCGCTGCCCAGCGGTGATTTCCTGATCAAGGCCCTGACGC
CGATCGAGAACTTCAACGAGTTCTTCGACAGCGAATTCTCCGACGACGAGTTCGACACCGTCGGCGGGCTGGTGATGAGC
GCGTTCGGGCACTTGCCAAAACGCAACGAAATCACTGAAATCGGCGCCTATCGTTTCCGCATCCTGAACGCCGACAGCCG
TCGGATTCATTTGCTGCGACTGACCCCAATCGCCCGGTAA

Upstream 100 bases:

>100_bases
AACGCGAGTTGCTTGCCGAATTGGGTTATCCCGATCCGTACGCGGACGACGAAACCGAAACATCCCCTACTGTTACAACA
AAGGATTCAGAGTAATCGCT

Downstream 100 bases:

>100_bases
AAAATCTAAGGATTGAAATGCGCTGGACAACCCGTCCCGGCTGGCCCGGTAACCTGCTGGCCGTGGCGGCCGGTGCAATC
ACCACCTTCGCGCTGGCACC

Product: transporter-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MSEDRSSNGQKSWLGKLTQAFAHEPKNRQELLELLRDAHQNKLLDSEALAIVEGAIQVADLQVRDIMVPRSQMISIKATQ
TPREFLPAVVDSAHSRYPVIGESHDDVMGVLLAKDLLPLILKENGDSFNIKDLLRPATFVPESKRLNVLLREFRANHNHM
AIVIDEYGGVAGLVTIEDVLEQIVGDIEDEHDVEEDSYIKPLPSGDFLIKALTPIENFNEFFDSEFSDDEFDTVGGLVMS
AFGHLPKRNEITEIGAYRFRILNADSRRIHLLRLTPIAR

Sequences:

>Translated_279_residues
MSEDRSSNGQKSWLGKLTQAFAHEPKNRQELLELLRDAHQNKLLDSEALAIVEGAIQVADLQVRDIMVPRSQMISIKATQ
TPREFLPAVVDSAHSRYPVIGESHDDVMGVLLAKDLLPLILKENGDSFNIKDLLRPATFVPESKRLNVLLREFRANHNHM
AIVIDEYGGVAGLVTIEDVLEQIVGDIEDEHDVEEDSYIKPLPSGDFLIKALTPIENFNEFFDSEFSDDEFDTVGGLVMS
AFGHLPKRNEITEIGAYRFRILNADSRRIHLLRLTPIAR
>Mature_278_residues
SEDRSSNGQKSWLGKLTQAFAHEPKNRQELLELLRDAHQNKLLDSEALAIVEGAIQVADLQVRDIMVPRSQMISIKATQT
PREFLPAVVDSAHSRYPVIGESHDDVMGVLLAKDLLPLILKENGDSFNIKDLLRPATFVPESKRLNVLLREFRANHNHMA
IVIDEYGGVAGLVTIEDVLEQIVGDIEDEHDVEEDSYIKPLPSGDFLIKALTPIENFNEFFDSEFSDDEFDTVGGLVMSA
FGHLPKRNEITEIGAYRFRILNADSRRIHLLRLTPIAR

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=209, Percent_Identity=27.7511961722488, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI40068055, Length=189, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI40068053, Length=189, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI94681046, Length=185, Percent_Identity=28.6486486486486, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1786879, Length=268, Percent_Identity=52.6119402985075, Blast_Score=266, Evalue=9e-73,
Organism=Escherichia coli, GI145693175, Length=220, Percent_Identity=29.5454545454545, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1788119, Length=228, Percent_Identity=31.5789473684211, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082033, Length=259, Percent_Identity=25.4826254826255, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1790664, Length=229, Percent_Identity=26.2008733624454, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 31421; Mature: 31290

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDRSSNGQKSWLGKLTQAFAHEPKNRQELLELLRDAHQNKLLDSEALAIVEGAIQVAD
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
LQVRDIMVPRSQMISIKATQTPREFLPAVVDSAHSRYPVIGESHDDVMGVLLAKDLLPLI
CHHHHEECCHHHEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LKENGDSFNIKDLLRPATFVPESKRLNVLLREFRANHNHMAIVIDEYGGVAGLVTIEDVL
HHCCCCCCCHHHHHCCHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEHHHHHHH
EQIVGDIEDEHDVEEDSYIKPLPSGDFLIKALTPIENFNEFFDSEFSDDEFDTVGGLVMS
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHH
AFGHLPKRNEITEIGAYRFRILNADSRRIHLLRLTPIAR
HHCCCCCCCCHHHHCCEEEEEECCCCCEEEEEEECCCCC
>Mature Secondary Structure 
SEDRSSNGQKSWLGKLTQAFAHEPKNRQELLELLRDAHQNKLLDSEALAIVEGAIQVAD
CCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
LQVRDIMVPRSQMISIKATQTPREFLPAVVDSAHSRYPVIGESHDDVMGVLLAKDLLPLI
CHHHHEECCHHHEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LKENGDSFNIKDLLRPATFVPESKRLNVLLREFRANHNHMAIVIDEYGGVAGLVTIEDVL
HHCCCCCCCHHHHHCCHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEHHHHHHH
EQIVGDIEDEHDVEEDSYIKPLPSGDFLIKALTPIENFNEFFDSEFSDDEFDTVGGLVMS
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHH
AFGHLPKRNEITEIGAYRFRILNADSRRIHLLRLTPIAR
HHCCCCCCCCHHHHCCEEEEEECCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]