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The map label for this gene is yafC [C]

Identifier: 77461122

GI number: 77461122

Start: 5524373

End: 5525284

Strand: Direct

Name: yafC [C]

Synonym: Pfl01_4901

Alternate gene names: 77461122

Gene position: 5524373-5525284 (Clockwise)

Preceding gene: 77461119

Following gene: 77461123

Centisome position: 85.8

GC content: 62.83

Gene sequence:

>912_bases
ATGCAGAGACACTTCGACGATCTTCAGCTGGGCAGCATCGAGCTGTTTTGCCTGGCCGCCGAGTGCGGCAGTTTCACCGG
CGCGGCGCAGGCGGCTTCGGTGACGCCGGCAGCGGTGAGCCGCTCGGTATCCCGCATGGAGGAACGCCTGGGCGTGCGGC
TGTTCGCGCGTACCACCCGCAGCGTGAAACTGACCGACAGCGGCCGGCGCTATTACGAAGAATGCAGTCAGGCGCTGGCA
CAACTGGTCGAGGCGCAGCGGGAAGTCATGGGCCAGCAGCAGGAACCGTCCGGCACCCTGCGTATCAGTATTCCTACGAC
CTACGCCCATCACCGAATCCTGCCGCTGCTGCCGGCCTTTCGCGCGCGCTTCCCGCAGGTGAAGGTGGACATGCACATCA
GCAACCGCAACATCGACTTCGTCGGCGAGGGCTACGACATGGCGATCCGCGTGCGGGCGATTCCCGATTCCGGCCTGATC
GCCCGCCACTTGGAAGATGCGGCGCTGGTGATGGTTGCCAGCCCCGATTACCTCAAACGCGCCGGCACGCCGCAGACCCT
CGAAGACCTCGAACAGCACGAGTGCATCCAGTACGAATTACCCAGCAACGGGCGGCGGATCACCTGGCTGTTTTACGACG
AAGAGACGCCACGGGAAATCCTCGCCGAGGGCAATTTCTGCTGCTCGGACGATGTGCTCGGTGGCGTGACCCTGGCCAGG
CACGGTGCCGGATTGTTCCAGACCTATCGCTTCATTGTCGAAAAAGAACTGGCCGACGGCTCGCTGATAGAAGTGCTCAA
ACCCTACAGCGGACGCTCGCGGCCGTTCACCTTGTTGTACCCGCAGAATCGCCACATGCCGCTGCGTGTCAGGGCTTTCA
TCGATTTTCTGGTGGAGCAGTTGCCGCACTGA

Upstream 100 bases:

>100_bases
TGCGGGAGCCGCAAAAGCCGCGCGCAAAATGGTAAGCAGTTCTTTCGCAGCGGCCACGCATTTGCTACATACGAAGACTC
ATTCCCCGGCGTAATCAATC

Downstream 100 bases:

>100_bases
ATTGCATCAGTGTGCGATCACCGCCCACAAAACCGGGTCGTCGATGCAGGGCAATTGATTAAAGTAACCATCTAGTACAA
TTTAACTCCACAGGTCGAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MQRHFDDLQLGSIELFCLAAECGSFTGAAQAASVTPAAVSRSVSRMEERLGVRLFARTTRSVKLTDSGRRYYEECSQALA
QLVEAQREVMGQQQEPSGTLRISIPTTYAHHRILPLLPAFRARFPQVKVDMHISNRNIDFVGEGYDMAIRVRAIPDSGLI
ARHLEDAALVMVASPDYLKRAGTPQTLEDLEQHECIQYELPSNGRRITWLFYDEETPREILAEGNFCCSDDVLGGVTLAR
HGAGLFQTYRFIVEKELADGSLIEVLKPYSGRSRPFTLLYPQNRHMPLRVRAFIDFLVEQLPH

Sequences:

>Translated_303_residues
MQRHFDDLQLGSIELFCLAAECGSFTGAAQAASVTPAAVSRSVSRMEERLGVRLFARTTRSVKLTDSGRRYYEECSQALA
QLVEAQREVMGQQQEPSGTLRISIPTTYAHHRILPLLPAFRARFPQVKVDMHISNRNIDFVGEGYDMAIRVRAIPDSGLI
ARHLEDAALVMVASPDYLKRAGTPQTLEDLEQHECIQYELPSNGRRITWLFYDEETPREILAEGNFCCSDDVLGGVTLAR
HGAGLFQTYRFIVEKELADGSLIEVLKPYSGRSRPFTLLYPQNRHMPLRVRAFIDFLVEQLPH
>Mature_303_residues
MQRHFDDLQLGSIELFCLAAECGSFTGAAQAASVTPAAVSRSVSRMEERLGVRLFARTTRSVKLTDSGRRYYEECSQALA
QLVEAQREVMGQQQEPSGTLRISIPTTYAHHRILPLLPAFRARFPQVKVDMHISNRNIDFVGEGYDMAIRVRAIPDSGLI
ARHLEDAALVMVASPDYLKRAGTPQTLEDLEQHECIQYELPSNGRRITWLFYDEETPREILAEGNFCCSDDVLGGVTLAR
HGAGLFQTYRFIVEKELADGSLIEVLKPYSGRSRPFTLLYPQNRHMPLRVRAFIDFLVEQLPH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=33.7931034482759, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=32.8719723183391, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=30.1694915254237, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=29.8969072164948, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=29.8969072164948, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789440, Length=281, Percent_Identity=27.7580071174377, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=27.681660899654, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788706, Length=190, Percent_Identity=32.1052631578947, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789173, Length=257, Percent_Identity=29.1828793774319, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI157672245, Length=119, Percent_Identity=36.9747899159664, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788481, Length=296, Percent_Identity=26.3513513513513, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786448, Length=295, Percent_Identity=24.406779661017, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788297, Length=168, Percent_Identity=30.3571428571429, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786508, Length=231, Percent_Identity=26.4069264069264, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082132, Length=272, Percent_Identity=26.1029411764706, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI145693105, Length=123, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790262, Length=183, Percent_Identity=30.6010928961749, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=122, Percent_Identity=29.5081967213115, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790208, Length=170, Percent_Identity=31.1764705882353, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34199; Mature: 34199

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRHFDDLQLGSIELFCLAAECGSFTGAAQAASVTPAAVSRSVSRMEERLGVRLFARTTR
CCCCCCCCCCCCEEEEEEEECCCCCCCCCHHCCCCHHHHHHHHHHHHHHHCEEEEEECCC
SVKLTDSGRRYYEECSQALAQLVEAQREVMGQQQEPSGTLRISIPTTYAHHRILPLLPAF
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
RARFPQVKVDMHISNRNIDFVGEGYDMAIRVRAIPDSGLIARHLEDAALVMVASPDYLKR
HCCCCCEEEEEEECCCCEEEEECCCEEEEEEEECCCCCHHHHHCCCEEEEEEECCHHHHH
AGTPQTLEDLEQHECIQYELPSNGRRITWLFYDEETPREILAEGNFCCSDDVLGGVTLAR
CCCCHHHHHHHHCCCEEEECCCCCCEEEEEEECCCCCHHHHHCCCCEECCCCCCCCHHHH
HGAGLFQTYRFIVEKELADGSLIEVLKPYSGRSRPFTLLYPQNRHMPLRVRAFIDFLVEQ
CCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHH
LPH
CCC
>Mature Secondary Structure
MQRHFDDLQLGSIELFCLAAECGSFTGAAQAASVTPAAVSRSVSRMEERLGVRLFARTTR
CCCCCCCCCCCCEEEEEEEECCCCCCCCCHHCCCCHHHHHHHHHHHHHHHCEEEEEECCC
SVKLTDSGRRYYEECSQALAQLVEAQREVMGQQQEPSGTLRISIPTTYAHHRILPLLPAF
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
RARFPQVKVDMHISNRNIDFVGEGYDMAIRVRAIPDSGLIARHLEDAALVMVASPDYLKR
HCCCCCEEEEEEECCCCEEEEECCCEEEEEEEECCCCCHHHHHCCCEEEEEEECCHHHHH
AGTPQTLEDLEQHECIQYELPSNGRRITWLFYDEETPREILAEGNFCCSDDVLGGVTLAR
CCCCHHHHHHHHCCCEEEECCCCCCEEEEEEECCCCCHHHHHCCCCEECCCCCCCCHHHH
HGAGLFQTYRFIVEKELADGSLIEVLKPYSGRSRPFTLLYPQNRHMPLRVRAFIDFLVEQ
CCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHH
LPH
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]