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The map label for this gene is lspA [H]

Identifier: 77461072

GI number: 77461072

Start: 5469594

End: 5470106

Strand: Reverse

Name: lspA [H]

Synonym: Pfl01_4851

Alternate gene names: 77461072

Gene position: 5470106-5469594 (Counterclockwise)

Preceding gene: 77461073

Following gene: 77461071

Centisome position: 84.96

GC content: 59.26

Gene sequence:

>513_bases
ATGCCTAATGCCGTTGGCCGTTTCGGACGGCTGAGCTGGCTCTGGTTGAGCTTGCTGGTTCTGGTCATCGACCAGGCCAG
CAAGTTCTACTTCGAAGGCAAGCTCGAGATGTTCCAGCAGATCGTGGTCATTCCCGATCTGTTCAGCTGGACGCTGGCCT
ACAACACCGGCGCTGCCTTCAGCTTCCTCGCGGACAGCTCCGGCTGGCAGCGCTGGCTGTTTGCCCTGATCGCGATTGCG
GTCAGTGCGGTGCTGGTGGTCTGGCTCAAACGCCTGGGTCGCAACGAAACCTGGCTGGCCATTGCGCTGGCGCTGGTGCT
GGGCGGCGCACTGGGCAACCTTTATGACCGCATTGCCCTCGGCCATGTGATCGATTTCATTCTGGTGCACTGGCAGAACC
GCTGGTACTTCCCGGCGTTCAATTTCGCCGACAGCGCCATCACCGTTGGCGCGGTGATGCTGGCACTGGACATGTTCAAA
AGTAAAAAAACCGGAGAAGCCGTTCATGACTGA

Upstream 100 bases:

>100_bases
TGCTGGCACTGCCGCGAAGACGTCGGCGTGAACCCGGAGCATCCGGAGATCTGCGGCCGTTGCGTGGACAACATCGATGG
CGCCGGTGAGGTTCGTCACT

Downstream 100 bases:

>100_bases
ACAGGTATTGGCTGAGCAACGCATCGGCCAGAACACGGAAGTCACCTTGCACTTTGCATTGCGCCTGGAGAACGGCGACA
CGGTCGACAGTACTTTCGAC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MPNAVGRFGRLSWLWLSLLVLVIDQASKFYFEGKLEMFQQIVVIPDLFSWTLAYNTGAAFSFLADSSGWQRWLFALIAIA
VSAVLVVWLKRLGRNETWLAIALALVLGGALGNLYDRIALGHVIDFILVHWQNRWYFPAFNFADSAITVGAVMLALDMFK
SKKTGEAVHD

Sequences:

>Translated_170_residues
MPNAVGRFGRLSWLWLSLLVLVIDQASKFYFEGKLEMFQQIVVIPDLFSWTLAYNTGAAFSFLADSSGWQRWLFALIAIA
VSAVLVVWLKRLGRNETWLAIALALVLGGALGNLYDRIALGHVIDFILVHWQNRWYFPAFNFADSAITVGAVMLALDMFK
SKKTGEAVHD
>Mature_169_residues
PNAVGRFGRLSWLWLSLLVLVIDQASKFYFEGKLEMFQQIVVIPDLFSWTLAYNTGAAFSFLADSSGWQRWLFALIAIAV
SAVLVVWLKRLGRNETWLAIALALVLGGALGNLYDRIALGHVIDFILVHWQNRWYFPAFNFADSAITVGAVMLALDMFKS
KKTGEAVHD

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=156, Percent_Identity=44.2307692307692, Blast_Score=120, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 19114; Mature: 18982

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNAVGRFGRLSWLWLSLLVLVIDQASKFYFEGKLEMFQQIVVIPDLFSWTLAYNTGAAF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SFLADSSGWQRWLFALIAIAVSAVLVVWLKRLGRNETWLAIALALVLGGALGNLYDRIAL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GHVIDFILVHWQNRWYFPAFNFADSAITVGAVMLALDMFKSKKTGEAVHD
HHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PNAVGRFGRLSWLWLSLLVLVIDQASKFYFEGKLEMFQQIVVIPDLFSWTLAYNTGAAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SFLADSSGWQRWLFALIAIAVSAVLVVWLKRLGRNETWLAIALALVLGGALGNLYDRIAL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GHVIDFILVHWQNRWYFPAFNFADSAITVGAVMLALDMFKSKKTGEAVHD
HHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA