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The map label for this gene is 77461014

Identifier: 77461014

GI number: 77461014

Start: 5409193

End: 5410749

Strand: Direct

Name: 77461014

Synonym: Pfl01_4793

Alternate gene names: NA

Gene position: 5409193-5410749 (Clockwise)

Preceding gene: 77461010

Following gene: 77461015

Centisome position: 84.01

GC content: 60.5

Gene sequence:

>1557_bases
GTGAGCCAGTCCCTGATCGCTGCCCTGCAAAACCCGGCCCTCTACCCGCATCCCGTCGAAGGGTTCCAGGTCATCGAAAC
CCATATCTCGTGGGTACTGCTCACCGGTCCCTACGCCTATAAAGTGAAGAAACCGGTGAACTTCGGTTTCCTCGACTTCA
CCAGCCTCGAATCCCGTGAGCACTTCTGCGGTGAAGAGCTGCGCCTGAACCAGCGCCTGACCGAAGATTTGTATCTGGAA
GTGATTCCAGTGACCGGCAGCGCCGAAGCCCCGCAACTGGGTGGCGACGGCCCGGCCATCGAGTACGTGCTGAAAATGCG
TCAGTTCCCGCAGTCCGGCCTGCTCAGCACCCTGCAAGCCAACGGCGAGCTGACCACCGCGCACATCGACGCGATGGCCG
AGCAAATCGCCCGCTTCCACCTCAACGCGCCGAAAGTCCCGGCCGAGCACGATGCCGGCACGCCTGAAAGCGTGATGGCG
CCGGTACGCCAGAACTTCGAACAGATCCTGCCGTTCCTCAGCGACAAGAACGATCTGCTGCAACTCGACGCTCTGCAAGC
ATGGGCTGAAAGCAGCTTCGATCGCCTCAAGCCGCTGTTCGCCCAACGCAAGACCGACGGTTTCACTCGCGAATGCCACG
GTGACATTCACCTGGGCAACGCCACGCTGATCGACGGCAAGGTCGTGATCTTCGACTGCATCGAATTCAACGAACCGTTC
CGCTTCACCGACGTATGGGCCGACACCGGCTTCCTGGCGATGGACCTTGAAGACCGTGGCCTGAAATCCCTGGCCCGTCG
TTTCATCAGCCAATACCTGGAACTGACCGGCGACTATCAAGGCCTGGAAGTGCTGAACTTCTACAAAGCGTACCGTGCGC
TGGTGCGTGCGAAAGTCGCACTGTTCAGCATGCCGGCCGACGCGACACCGGTGCAGCGCGCCACCACCCTGCGCCAGTAC
CGCAACTACGCCAACCTGGCGGAAAGCTACAGCACCATTCCTTCGCGCTTCATGGCGATCACCCATGGCGTTTCCGCTGT
CGGTAAAAGCCATGTGGCCATGCGTCTGGTCGAAGCACTGGGCGCGATCCGCCTGCGTTCCGATGTCGAGCGCAAACGTC
TGTTCGGTGAGCAAACCGTTGCCAATGATGTTCAGGCCGGGATCTACAGCACCGACGCCAGCACTGCAACCTATGCGCGT
CTGCATGAAATTGCCGAAGTGATTTTGCACGCCGGTTTCCCGGTGGTGATCGATGCCACTTACCTCAAGCGCGAACAACG
CGACAACGCCGCCAAAGTCGCTGAAGCCACTGGCACGCCTTTCCTGATCCTTGACTGCAACGCTCCGCAGGCAGTGATCG
AGAGCTGGCTGGCGATTCGTCAGGCAGACAAAAAGGATCCGTCCGACGCGACCCTTGCCGTGATCGAAGCACAACAGGCC
AACCGCGAAGCCCTGACGCCGGAAGAAATCCTGCGCAGCAAACGCGTGCAGACCAATGAGTCCGGCACCCTGGACACCGT
TGTGGCGCAGATCCGCCAGCGCCTGCCAGGTCTGTAA

Upstream 100 bases:

>100_bases
CTTTATTCATACTCAACAGGAGCGCTCCGAGGTTTGCGTCGGGCTGGCGAGCGGCCATAATGAGCGCCTTGAACTTCCCC
CAGTCTCTGAAGGATCGTCC

Downstream 100 bases:

>100_bases
GAAACTATTTCGGCCGTGAAGCCCTCGCCCGCTTCACGGCCGTCAAATAGTGGCACTATACTGGCGTCATAAAACCAACA
GGTGATTTGACATGAGCCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MSQSLIAALQNPALYPHPVEGFQVIETHISWVLLTGPYAYKVKKPVNFGFLDFTSLESREHFCGEELRLNQRLTEDLYLE
VIPVTGSAEAPQLGGDGPAIEYVLKMRQFPQSGLLSTLQANGELTTAHIDAMAEQIARFHLNAPKVPAEHDAGTPESVMA
PVRQNFEQILPFLSDKNDLLQLDALQAWAESSFDRLKPLFAQRKTDGFTRECHGDIHLGNATLIDGKVVIFDCIEFNEPF
RFTDVWADTGFLAMDLEDRGLKSLARRFISQYLELTGDYQGLEVLNFYKAYRALVRAKVALFSMPADATPVQRATTLRQY
RNYANLAESYSTIPSRFMAITHGVSAVGKSHVAMRLVEALGAIRLRSDVERKRLFGEQTVANDVQAGIYSTDASTATYAR
LHEIAEVILHAGFPVVIDATYLKREQRDNAAKVAEATGTPFLILDCNAPQAVIESWLAIRQADKKDPSDATLAVIEAQQA
NREALTPEEILRSKRVQTNESGTLDTVVAQIRQRLPGL

Sequences:

>Translated_518_residues
MSQSLIAALQNPALYPHPVEGFQVIETHISWVLLTGPYAYKVKKPVNFGFLDFTSLESREHFCGEELRLNQRLTEDLYLE
VIPVTGSAEAPQLGGDGPAIEYVLKMRQFPQSGLLSTLQANGELTTAHIDAMAEQIARFHLNAPKVPAEHDAGTPESVMA
PVRQNFEQILPFLSDKNDLLQLDALQAWAESSFDRLKPLFAQRKTDGFTRECHGDIHLGNATLIDGKVVIFDCIEFNEPF
RFTDVWADTGFLAMDLEDRGLKSLARRFISQYLELTGDYQGLEVLNFYKAYRALVRAKVALFSMPADATPVQRATTLRQY
RNYANLAESYSTIPSRFMAITHGVSAVGKSHVAMRLVEALGAIRLRSDVERKRLFGEQTVANDVQAGIYSTDASTATYAR
LHEIAEVILHAGFPVVIDATYLKREQRDNAAKVAEATGTPFLILDCNAPQAVIESWLAIRQADKKDPSDATLAVIEAQQA
NREALTPEEILRSKRVQTNESGTLDTVVAQIRQRLPGL
>Mature_517_residues
SQSLIAALQNPALYPHPVEGFQVIETHISWVLLTGPYAYKVKKPVNFGFLDFTSLESREHFCGEELRLNQRLTEDLYLEV
IPVTGSAEAPQLGGDGPAIEYVLKMRQFPQSGLLSTLQANGELTTAHIDAMAEQIARFHLNAPKVPAEHDAGTPESVMAP
VRQNFEQILPFLSDKNDLLQLDALQAWAESSFDRLKPLFAQRKTDGFTRECHGDIHLGNATLIDGKVVIFDCIEFNEPFR
FTDVWADTGFLAMDLEDRGLKSLARRFISQYLELTGDYQGLEVLNFYKAYRALVRAKVALFSMPADATPVQRATTLRQYR
NYANLAESYSTIPSRFMAITHGVSAVGKSHVAMRLVEALGAIRLRSDVERKRLFGEQTVANDVQAGIYSTDASTATYARL
HEIAEVILHAGFPVVIDATYLKREQRDNAAKVAEATGTPFLILDCNAPQAVIESWLAIRQADKKDPSDATLAVIEAQQAN
REALTPEEILRSKRVQTNESGTLDTVVAQIRQRLPGL

Specific function: Some isolated peptides of this protein are able to bind to human U937 monocytoblastic and A549 epithelial cell lines [H]

COG id: COG2187

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR010488 [H]

Pfam domain/function: PF06414 Zeta_toxin [H]

EC number: NA

Molecular weight: Translated: 57593; Mature: 57462

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSLIAALQNPALYPHPVEGFQVIETHISWVLLTGPYAYKVKKPVNFGFLDFTSLESRE
CCCHHHHHHHCCCCCCCCCCHHHHHHHHHCEEEEECCEEEEEECCCCCCCEECCCCCCHH
HFCGEELRLNQRLTEDLYLEVIPVTGSAEAPQLGGDGPAIEYVLKMRQFPQSGLLSTLQA
HHCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHC
NGELTTAHIDAMAEQIARFHLNAPKVPAEHDAGTPESVMAPVRQNFEQILPFLSDKNDLL
CCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
QLDALQAWAESSFDRLKPLFAQRKTDGFTRECHGDIHLGNATLIDGKVVIFDCIEFNEPF
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHCCCCEEECCEEEECCCEEEEEEECCCCCC
RFTDVWADTGFLAMDLEDRGLKSLARRFISQYLELTGDYQGLEVLNFYKAYRALVRAKVA
EEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LFSMPADATPVQRATTLRQYRNYANLAESYSTIPSRFMAITHGVSAVGKSHVAMRLVEAL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIRLRSDVERKRLFGEQTVANDVQAGIYSTDASTATYARLHEIAEVILHAGFPVVIDAT
HHHHHHHHHHHHHHHCHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEHH
YLKREQRDNAAKVAEATGTPFLILDCNAPQAVIESWLAIRQADKKDPSDATLAVIEAQQA
HHHHHHCCCHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHC
NREALTPEEILRSKRVQTNESGTLDTVVAQIRQRLPGL
CCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQSLIAALQNPALYPHPVEGFQVIETHISWVLLTGPYAYKVKKPVNFGFLDFTSLESRE
CCHHHHHHHCCCCCCCCCCHHHHHHHHHCEEEEECCEEEEEECCCCCCCEECCCCCCHH
HFCGEELRLNQRLTEDLYLEVIPVTGSAEAPQLGGDGPAIEYVLKMRQFPQSGLLSTLQA
HHCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHC
NGELTTAHIDAMAEQIARFHLNAPKVPAEHDAGTPESVMAPVRQNFEQILPFLSDKNDLL
CCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
QLDALQAWAESSFDRLKPLFAQRKTDGFTRECHGDIHLGNATLIDGKVVIFDCIEFNEPF
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHCCCCEEECCEEEECCCEEEEEEECCCCCC
RFTDVWADTGFLAMDLEDRGLKSLARRFISQYLELTGDYQGLEVLNFYKAYRALVRAKVA
EEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LFSMPADATPVQRATTLRQYRNYANLAESYSTIPSRFMAITHGVSAVGKSHVAMRLVEAL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIRLRSDVERKRLFGEQTVANDVQAGIYSTDASTATYARLHEIAEVILHAGFPVVIDAT
HHHHHHHHHHHHHHHCHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEHH
YLKREQRDNAAKVAEATGTPFLILDCNAPQAVIESWLAIRQADKKDPSDATLAVIEAQQA
HHHHHHCCCHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHC
NREALTPEEILRSKRVQTNESGTLDTVVAQIRQRLPGL
CCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]