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The map label for this gene is ipk [H]

Identifier: 77460973

GI number: 77460973

Start: 5356029

End: 5356880

Strand: Direct

Name: ipk [H]

Synonym: Pfl01_4752

Alternate gene names: 77460973

Gene position: 5356029-5356880 (Clockwise)

Preceding gene: 77460972

Following gene: 77460974

Centisome position: 83.19

GC content: 56.1

Gene sequence:

>852_bases
ATGACCGCTCCACGCCTCACTTTGCCTTCACCGGCCAAACTCAACCTGATGTTGCACATTCTCGGTCGCCGTGAAGACGG
TTATCACGAATTGCAGACGCTTTTTCAGTTCCTCGACTACGGCGACGAAATCACCTTCGCCGTCCGTGACGACGGCGTGA
TTCGCCTGCACACCGAATTCGACGGAGTGCCCCACGACAGCAACCTGATCGTGCGCGCGGCGAAAAAACTGCAGGAACAA
TCCGCCTGCTCGCTCGGCATCGACATCTGGATCGACAAGATCCTGCCGATGGGCGGCGGCATCGGGGGCGGCAGCTCGAA
TGCGGCCACCACCCTGCTTGGCCTCAATCATTTGTGGCGACTGGGTTGGGATGAAGATCGCCTGGCTGCACTGGGCCTGA
CGCTGGGCGCCGACGTGCCGGTGTTCGTGCGTGGTCATGCGGCTTTTGCCGAAGGTGTCGGTGAGAAACTGACCCCGGTC
GAGCCCGCCGAACCGTGGTACGTCGTGCTCGTTCCGCAAGTCTCTGTTAGTACGGCAGAAATTTTTTCAGATCCTTTGTT
GACACGTAACACGCCGCCCATTAAAGTGCGCCCCGTTCCCGAGGGAAACAGTCGAAATGACTGCTTGCCGGTGGTCTCGA
GGCGTTATCCAGAAGTACGTAACGCATTGAATTTGTTAGGTAATTTTACCGAAGCAAAACTTACCGGAACTGGAAGTTGT
GTGTTTGGGGGCTTCCCAAGCAAAGCTGAAGCTGATAAAGTCTCGGCCCTTCTGACAGAGACCCTTACAGGGTTTGTAGC
GAAAGGAAGCAACGTTTCGATGTTGCATCGCAAGCTGCAAAGTCTGCTCTAA

Upstream 100 bases:

>100_bases
CGGTTACTGGCTGCCCGAGCGGATCAAGCTGCACGGCAGCGATCTGGACGTGACGCTGGTGATCAAGACCTGGCAACCGC
GCAAACTGGGGCAATAACGC

Downstream 100 bases:

>100_bases
AGGAACCAAGTGCCCGGCACTTGCAAGCAACAGATACAGGGGCGTCGCCAAGCGGTAAGGCAGCAGGTTTTGATCCTGCC
ATGCGTTGGTTCGAATCCAG

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTAPRLTLPSPAKLNLMLHILGRREDGYHELQTLFQFLDYGDEITFAVRDDGVIRLHTEFDGVPHDSNLIVRAAKKLQEQ
SACSLGIDIWIDKILPMGGGIGGGSSNAATTLLGLNHLWRLGWDEDRLAALGLTLGADVPVFVRGHAAFAEGVGEKLTPV
EPAEPWYVVLVPQVSVSTAEIFSDPLLTRNTPPIKVRPVPEGNSRNDCLPVVSRRYPEVRNALNLLGNFTEAKLTGTGSC
VFGGFPSKAEADKVSALLTETLTGFVAKGSNVSMLHRKLQSLL

Sequences:

>Translated_283_residues
MTAPRLTLPSPAKLNLMLHILGRREDGYHELQTLFQFLDYGDEITFAVRDDGVIRLHTEFDGVPHDSNLIVRAAKKLQEQ
SACSLGIDIWIDKILPMGGGIGGGSSNAATTLLGLNHLWRLGWDEDRLAALGLTLGADVPVFVRGHAAFAEGVGEKLTPV
EPAEPWYVVLVPQVSVSTAEIFSDPLLTRNTPPIKVRPVPEGNSRNDCLPVVSRRYPEVRNALNLLGNFTEAKLTGTGSC
VFGGFPSKAEADKVSALLTETLTGFVAKGSNVSMLHRKLQSLL
>Mature_282_residues
TAPRLTLPSPAKLNLMLHILGRREDGYHELQTLFQFLDYGDEITFAVRDDGVIRLHTEFDGVPHDSNLIVRAAKKLQEQS
ACSLGIDIWIDKILPMGGGIGGGSSNAATTLLGLNHLWRLGWDEDRLAALGLTLGADVPVFVRGHAAFAEGVGEKLTPVE
PAEPWYVVLVPQVSVSTAEIFSDPLLTRNTPPIKVRPVPEGNSRNDCLPVVSRRYPEVRNALNLLGNFTEAKLTGTGSCV
FGGFPSKAEADKVSALLTETLTGFVAKGSNVSMLHRKLQSLL

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=281, Percent_Identity=56.9395017793594, Blast_Score=288, Evalue=3e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 30645; Mature: 30513

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPRLTLPSPAKLNLMLHILGRREDGYHELQTLFQFLDYGDEITFAVRDDGVIRLHTEF
CCCCCCCCCCCCHHEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECC
DGVPHDSNLIVRAAKKLQEQSACSLGIDIWIDKILPMGGGIGGGSSNAATTLLGLNHLWR
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
LGWDEDRLAALGLTLGADVPVFVRGHAAFAEGVGEKLTPVEPAEPWYVVLVPQVSVSTAE
CCCCCCHHEEEEEEECCCCCEEEECCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHH
IFSDPLLTRNTPPIKVRPVPEGNSRNDCLPVVSRRYPEVRNALNLLGNFTEAKLTGTGSC
HHCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCE
VFGGFPSKAEADKVSALLTETLTGFVAKGSNVSMLHRKLQSLL
EECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
TAPRLTLPSPAKLNLMLHILGRREDGYHELQTLFQFLDYGDEITFAVRDDGVIRLHTEF
CCCCCCCCCCCHHEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECC
DGVPHDSNLIVRAAKKLQEQSACSLGIDIWIDKILPMGGGIGGGSSNAATTLLGLNHLWR
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
LGWDEDRLAALGLTLGADVPVFVRGHAAFAEGVGEKLTPVEPAEPWYVVLVPQVSVSTAE
CCCCCCHHEEEEEEECCCCCEEEECCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHH
IFSDPLLTRNTPPIKVRPVPEGNSRNDCLPVVSRRYPEVRNALNLLGNFTEAKLTGTGSC
HHCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCE
VFGGFPSKAEADKVSALLTETLTGFVAKGSNVSMLHRKLQSLL
EECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA