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The map label for this gene is mmgC [H]

Identifier: 77460917

GI number: 77460917

Start: 5297802

End: 5298938

Strand: Reverse

Name: mmgC [H]

Synonym: Pfl01_4696

Alternate gene names: 77460917

Gene position: 5298938-5297802 (Counterclockwise)

Preceding gene: 77460919

Following gene: 77460915

Centisome position: 82.3

GC content: 59.37

Gene sequence:

>1137_bases
ATGATTCCCAGAACCTTGTTCAGCTCCGAGCACGAATTGTTCCGCGACAGCGTACGAACCTTCCTCGAAAAAGAGGCCGT
GCCGTTCCATGGGCAATGGGAAAAACAAGGCTACATCGACCGCAAACTGTGGAACAAGGCAGGGGAGGCGGGGATGCTCT
GCTCGAACCTGCCGGAGGAATACGGCGGGTTGGGGGCGGACTTTCTTTACAGCGCGGTCGTGATCGAAGAAGTCGGGCGG
CTGGGTTTGACCGGTATCGGTTTTTCACTGCATTCGGACATCGTCGCGCCGTACATCCTGCATTACGGCAGCGAAGCGCT
GAAGCAGAAATACCTGCCGAAACTGGTGTCTGGCGAGATGGTTACCGCGATCGCCATGACCGAGCCCGGCGCCGGTTCCG
ACCTGCAAGGGGTCAAGACCACGGCGGTACTGGATGGCGACGAATATGTGATCAACGGTTCGAAAACCTTTATCACCAAC
GGCTTCCTGGCGGATCTGGTGATTGTCGTGGCCAAGACCGATCCCAAGGCCGGTGCCAAGGGTACCAGCCTGTTTCTGGT
GGAGGCGAACACACCGGGCTTCGACAAGGGCAAACGCCTGGATAAGGTCGGAATGAAGGCTCAGGACACGTCGGAATTGT
TCTTCCAGGACGTGCGCGTGCCGAAAGAAAACCTCTTGGGTCAGGCCGGGGCGGGATTTGCCTATCTGATGCAGGAACTG
CCGCAGGAGCGTCTGACTGTGGCGATTGGCGGTCTGGCTTCAGCCGAGGCGGCGCTGCAATGGACGCTGGATTACACCCG
CGAGCGCAAGGCGTTCGGCAAGTCGATTGCCGACTTCCAGAATACCCGCTTCAAACTGGCGGAAATGGCCACCGAGATTC
AGATCGGCCGGGTGTTCGTCGACCGCTGCCTTGAGCTGCATCTGCAAGGCAAGCTGGATGTGCCGACGGCGGCGATGGCC
AAGTACTGGGGCACCGACCTGCAATGCAAGGTGCTCGACGAGTGCGTGCAACTGCATGGCGGTTACGGTTTCATGTGGGA
ATACCCGGTGGCCCGGGCCTGGGCGGATGCGCGGGTGCAGCGCATCTATGCCGGCACCAATGAAATCATGAAGGAGATCA
TTGCGCGGTCGCTTTGA

Upstream 100 bases:

>100_bases
ATCGTCTTATTTTTTGTCGGATGTGTCCAGTGTCCTGTATCGGAAGCGAGGCTTAGTCTCTGAAGGTCTGATCCCTCCAA
CAATAAATAAAAGGTGCCGC

Downstream 100 bases:

>100_bases
GTTTTGCAGTGAGTTGACTGGCCCCTTCGCGAGCAGGCTCGCTCCCACAATCATCACGCTGTACCTGTGGGAGCGAGCCT
GGTCGCGAAGCTTTTAGCGG

Product: acyl-CoA dehydrogenase-like protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MIPRTLFSSEHELFRDSVRTFLEKEAVPFHGQWEKQGYIDRKLWNKAGEAGMLCSNLPEEYGGLGADFLYSAVVIEEVGR
LGLTGIGFSLHSDIVAPYILHYGSEALKQKYLPKLVSGEMVTAIAMTEPGAGSDLQGVKTTAVLDGDEYVINGSKTFITN
GFLADLVIVVAKTDPKAGAKGTSLFLVEANTPGFDKGKRLDKVGMKAQDTSELFFQDVRVPKENLLGQAGAGFAYLMQEL
PQERLTVAIGGLASAEAALQWTLDYTRERKAFGKSIADFQNTRFKLAEMATEIQIGRVFVDRCLELHLQGKLDVPTAAMA
KYWGTDLQCKVLDECVQLHGGYGFMWEYPVARAWADARVQRIYAGTNEIMKEIIARSL

Sequences:

>Translated_378_residues
MIPRTLFSSEHELFRDSVRTFLEKEAVPFHGQWEKQGYIDRKLWNKAGEAGMLCSNLPEEYGGLGADFLYSAVVIEEVGR
LGLTGIGFSLHSDIVAPYILHYGSEALKQKYLPKLVSGEMVTAIAMTEPGAGSDLQGVKTTAVLDGDEYVINGSKTFITN
GFLADLVIVVAKTDPKAGAKGTSLFLVEANTPGFDKGKRLDKVGMKAQDTSELFFQDVRVPKENLLGQAGAGFAYLMQEL
PQERLTVAIGGLASAEAALQWTLDYTRERKAFGKSIADFQNTRFKLAEMATEIQIGRVFVDRCLELHLQGKLDVPTAAMA
KYWGTDLQCKVLDECVQLHGGYGFMWEYPVARAWADARVQRIYAGTNEIMKEIIARSL
>Mature_378_residues
MIPRTLFSSEHELFRDSVRTFLEKEAVPFHGQWEKQGYIDRKLWNKAGEAGMLCSNLPEEYGGLGADFLYSAVVIEEVGR
LGLTGIGFSLHSDIVAPYILHYGSEALKQKYLPKLVSGEMVTAIAMTEPGAGSDLQGVKTTAVLDGDEYVINGSKTFITN
GFLADLVIVVAKTDPKAGAKGTSLFLVEANTPGFDKGKRLDKVGMKAQDTSELFFQDVRVPKENLLGQAGAGFAYLMQEL
PQERLTVAIGGLASAEAALQWTLDYTRERKAFGKSIADFQNTRFKLAEMATEIQIGRVFVDRCLELHLQGKLDVPTAAMA
KYWGTDLQCKVLDECVQLHGGYGFMWEYPVARAWADARVQRIYAGTNEIMKEIIARSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=52.7851458885942, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI4557233, Length=369, Percent_Identity=36.5853658536585, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=35.5437665782493, Blast_Score=242, Evalue=5e-64,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=37.2434017595308, Blast_Score=234, Evalue=8e-62,
Organism=Homo sapiens, GI4557231, Length=374, Percent_Identity=35.5614973262032, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI187960098, Length=374, Percent_Identity=35.5614973262032, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI4501859, Length=377, Percent_Identity=32.8912466843501, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI7656849, Length=377, Percent_Identity=31.8302387267904, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI76496475, Length=347, Percent_Identity=37.7521613832853, Blast_Score=202, Evalue=6e-52,
Organism=Homo sapiens, GI4557235, Length=347, Percent_Identity=37.7521613832853, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI21361497, Length=362, Percent_Identity=33.7016574585635, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI4503943, Length=382, Percent_Identity=29.8429319371728, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI7669494, Length=356, Percent_Identity=30.3370786516854, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI48976061, Length=290, Percent_Identity=31.0344827586207, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI211971008, Length=290, Percent_Identity=31.0344827586207, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI38505218, Length=377, Percent_Identity=29.4429708222812, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI218563752, Length=324, Percent_Identity=25, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87081958, Length=379, Percent_Identity=31.1345646437995, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1786223, Length=374, Percent_Identity=27.5401069518717, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI87081702, Length=355, Percent_Identity=23.943661971831, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=36.8, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17570075, Length=377, Percent_Identity=35.5437665782493, Blast_Score=238, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI17551932, Length=380, Percent_Identity=34.7368421052632, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17533517, Length=365, Percent_Identity=35.8904109589041, Blast_Score=225, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17508101, Length=375, Percent_Identity=33.3333333333333, Blast_Score=224, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI17534899, Length=377, Percent_Identity=35.5437665782493, Blast_Score=224, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI17569725, Length=377, Percent_Identity=35.2785145888594, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=33.2446808510638, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17506239, Length=379, Percent_Identity=32.4538258575198, Blast_Score=214, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI71990804, Length=284, Percent_Identity=37.6760563380282, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71985184, Length=350, Percent_Identity=34.2857142857143, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI71982178, Length=281, Percent_Identity=30.2491103202847, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=35.6521739130435, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71985192, Length=309, Percent_Identity=34.6278317152104, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17534353, Length=367, Percent_Identity=29.4277929155313, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=30.1255230125523, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17562446, Length=333, Percent_Identity=29.1291291291291, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17531913, Length=176, Percent_Identity=27.8409090909091, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=34.9333333333333, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI24660351, Length=370, Percent_Identity=37.2972972972973, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI24666513, Length=377, Percent_Identity=32.6259946949602, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24646207, Length=373, Percent_Identity=34.3163538873995, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI21355753, Length=374, Percent_Identity=35.8288770053476, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI281363737, Length=350, Percent_Identity=34, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI19920834, Length=380, Percent_Identity=30, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41699; Mature: 41699

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPRTLFSSEHELFRDSVRTFLEKEAVPFHGQWEKQGYIDRKLWNKAGEAGMLCSNLPEE
CCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHCCCHH
YGGLGADFLYSAVVIEEVGRLGLTGIGFSLHSDIVAPYILHYGSEALKQKYLPKLVSGEM
HCCCCHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCE
VTAIAMTEPGAGSDLQGVKTTAVLDGDEYVINGSKTFITNGFLADLVIVVAKTDPKAGAK
EEEEEEECCCCCCCCCCCEEEEEECCCEEEECCCCEEEECCHHHHEEEEEECCCCCCCCC
GTSLFLVEANTPGFDKGKRLDKVGMKAQDTSELFFQDVRVPKENLLGQAGAGFAYLMQEL
CCEEEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHC
PQERLTVAIGGLASAEAALQWTLDYTRERKAFGKSIADFQNTRFKLAEMATEIQIGRVFV
CHHHHEEEECCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRCLELHLQGKLDVPTAAMAKYWGTDLQCKVLDECVQLHGGYGFMWEYPVARAWADARVQ
HHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHH
RIYAGTNEIMKEIIARSL
HHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIPRTLFSSEHELFRDSVRTFLEKEAVPFHGQWEKQGYIDRKLWNKAGEAGMLCSNLPEE
CCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHCCCHH
YGGLGADFLYSAVVIEEVGRLGLTGIGFSLHSDIVAPYILHYGSEALKQKYLPKLVSGEM
HCCCCHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCE
VTAIAMTEPGAGSDLQGVKTTAVLDGDEYVINGSKTFITNGFLADLVIVVAKTDPKAGAK
EEEEEEECCCCCCCCCCCEEEEEECCCEEEECCCCEEEECCHHHHEEEEEECCCCCCCCC
GTSLFLVEANTPGFDKGKRLDKVGMKAQDTSELFFQDVRVPKENLLGQAGAGFAYLMQEL
CCEEEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHC
PQERLTVAIGGLASAEAALQWTLDYTRERKAFGKSIADFQNTRFKLAEMATEIQIGRVFV
CHHHHEEEECCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRCLELHLQGKLDVPTAAMAKYWGTDLQCKVLDECVQLHGGYGFMWEYPVARAWADARVQ
HHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHH
RIYAGTNEIMKEIIARSL
HHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]