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The map label for this gene is aer [H]

Identifier: 77460879

GI number: 77460879

Start: 5255023

End: 5256612

Strand: Reverse

Name: aer [H]

Synonym: Pfl01_4658

Alternate gene names: 77460879

Gene position: 5256612-5255023 (Counterclockwise)

Preceding gene: 77460880

Following gene: 77460873

Centisome position: 81.64

GC content: 64.97

Gene sequence:

>1590_bases
ATGAAGATCAATCTCCCGGTGACCGGGCGCAATGTCGATGTTGCGCCGGATGCGAACATTCTCTCGACCACCGATCTGAC
CAGCGCGATCACCTACGCCAACGACGACTTCATCAGGATCAGCGGTTACAGCCGCGACGAGCTGCTGGGTGCGCCGCACA
ATTTGCTGCGTCATCCGGACATGCCCGCGCAGGCGTTTGCCCATATGTGGCAGACGCTCAAGGGTGGGCGGTCGTGGATG
GGGCTGGTCAAGAATCGTTGCAAGAACGGTGATCACTACTGGGTCAGTGCTTATGTCACGCCGGTCACGCAGAACGGTGC
GGCGGTGGAGTATCAGTCGGTGCGCACGCGGCCGGATACGCGGCAGATTGCGGCAGCGGAGCGGGCGTATGCGCAGTTGC
GCGAGGGGCGGGTGGCGCGGTGGCCGCGGCTGCCGAGCCTGAGTTTGCGGGCGAAGATCATGGCGTTGACCAGTTCGTTG
CTGGCGCTGGTGCTGGGGATGGAAGCCTGGCTGCGGCCGGAGTCCATGGGCATCGAAGCCGCTGCGCTGGTGGCCGGCAG
TGGCGCGTGTGCGCTGGGCGTGGGTTGGTTATTGCGGCCGCTGGAGCATTTGACCGAGCGTGCCCGGCTGATTGCCGATA
ACCCGTTGAGCCAGGGCATTTATACCGGGCGGCGGGATCAGTTCGGGCAGATCGAGTTTGCCTTGCAGATGCTTGAAGCG
CAGGTCGGCGCGGTGGTGGGGCGGATCGGTGATGCATCGCAGCGGCTGGCCGGGCATGCGGCGCAATTGGTGGATCATCT
GCACAGCAGTCACACCAGCACGTTGGCGCAGCAGGCGGAAACCGATCAGGTGGCGGCGGCGATTCATCAGATGGCGGCCA
GTGTGGCCGAGGTGGCCAGCCATGCGCAGCAGGCGTCGGTGGCGGCGGACATGGCGGGTACGGAAACCCGTGAAGGTCAT
CTGCTGGTGGGCGAGAGTCGCAGTGCAGTGTTGCGGCTGGCCGAGGAGTTGGGGCGGGCGACCGAGGTGATTCATCAGCT
CGAAGGCCACAGCATCGAGATTTCCGGGGTGCTGGAGGTGATTCGCAGCATCGCTGAGCAGACCAACCTGCTGGCGCTCA
ACGCGGCGATCGAAGCGGCGCGGGCCGGGGATGCCGGGCGTGGGTTTGCGGTGGTCGCCGATGAGGTGCGTGGTCTGGCT
CAGCGTACTCAGCAGTCGACCAACGAGATTCAACGGATGATCAGCACCCTGCAAAACGGCGCGCGGGATGCGGTGCTGGT
GATGCAGCAGAGCAGTGAGCATGTGGATAACAGCGTCGAACAGGCCCAGCGTGCGGCCCGGGCCCTGGACGGGATCAGCG
GCCGGGTCGAGCAGATCACCGAGATGAGTCTGCAGATTGCGGCGGCGGTTGAAGAACAGAGCGCGGTGAGCGAGGACATC
AACCGCAACATCGTCAGTATTCGCACGGCCTGTGAACTGACGGTGGATGAGGGGCGCCAGAGCCAGCTCAACTCACAGGA
TGTGGCGGGGCTGGCGGGGGATTTGCGTTCGCTGGCGCGGGAGTTCTGGGGGCGGCGGCAGGGCGCTTAG

Upstream 100 bases:

>100_bases
CTAATTGCTCAGTTCCTGAGCCAGATCAACGTTTCACCAGTGAGTGCGCTTAGAGTCAGCAGCCCTGCCGACTCTTTCCA
ATAAAACGAGCGCGCTTTCC

Downstream 100 bases:

>100_bases
GCTGCTCGCAACGAGATGAACGCGTAGGTCTGCGGCGGTTCGGACACCACGTGTGCCCCGGCCGCCCGTACTTGCCCGGC
GATGTCGTCGCCGGAGACAT

Product: Pas/Pac sensor-containing chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MKINLPVTGRNVDVAPDANILSTTDLTSAITYANDDFIRISGYSRDELLGAPHNLLRHPDMPAQAFAHMWQTLKGGRSWM
GLVKNRCKNGDHYWVSAYVTPVTQNGAAVEYQSVRTRPDTRQIAAAERAYAQLREGRVARWPRLPSLSLRAKIMALTSSL
LALVLGMEAWLRPESMGIEAAALVAGSGACALGVGWLLRPLEHLTERARLIADNPLSQGIYTGRRDQFGQIEFALQMLEA
QVGAVVGRIGDASQRLAGHAAQLVDHLHSSHTSTLAQQAETDQVAAAIHQMAASVAEVASHAQQASVAADMAGTETREGH
LLVGESRSAVLRLAEELGRATEVIHQLEGHSIEISGVLEVIRSIAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLA
QRTQQSTNEIQRMISTLQNGARDAVLVMQQSSEHVDNSVEQAQRAARALDGISGRVEQITEMSLQIAAAVEEQSAVSEDI
NRNIVSIRTACELTVDEGRQSQLNSQDVAGLAGDLRSLAREFWGRRQGA

Sequences:

>Translated_529_residues
MKINLPVTGRNVDVAPDANILSTTDLTSAITYANDDFIRISGYSRDELLGAPHNLLRHPDMPAQAFAHMWQTLKGGRSWM
GLVKNRCKNGDHYWVSAYVTPVTQNGAAVEYQSVRTRPDTRQIAAAERAYAQLREGRVARWPRLPSLSLRAKIMALTSSL
LALVLGMEAWLRPESMGIEAAALVAGSGACALGVGWLLRPLEHLTERARLIADNPLSQGIYTGRRDQFGQIEFALQMLEA
QVGAVVGRIGDASQRLAGHAAQLVDHLHSSHTSTLAQQAETDQVAAAIHQMAASVAEVASHAQQASVAADMAGTETREGH
LLVGESRSAVLRLAEELGRATEVIHQLEGHSIEISGVLEVIRSIAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLA
QRTQQSTNEIQRMISTLQNGARDAVLVMQQSSEHVDNSVEQAQRAARALDGISGRVEQITEMSLQIAAAVEEQSAVSEDI
NRNIVSIRTACELTVDEGRQSQLNSQDVAGLAGDLRSLAREFWGRRQGA
>Mature_529_residues
MKINLPVTGRNVDVAPDANILSTTDLTSAITYANDDFIRISGYSRDELLGAPHNLLRHPDMPAQAFAHMWQTLKGGRSWM
GLVKNRCKNGDHYWVSAYVTPVTQNGAAVEYQSVRTRPDTRQIAAAERAYAQLREGRVARWPRLPSLSLRAKIMALTSSL
LALVLGMEAWLRPESMGIEAAALVAGSGACALGVGWLLRPLEHLTERARLIADNPLSQGIYTGRRDQFGQIEFALQMLEA
QVGAVVGRIGDASQRLAGHAAQLVDHLHSSHTSTLAQQAETDQVAAAIHQMAASVAEVASHAQQASVAADMAGTETREGH
LLVGESRSAVLRLAEELGRATEVIHQLEGHSIEISGVLEVIRSIAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLA
QRTQQSTNEIQRMISTLQNGARDAVLVMQQSSEHVDNSVEQAQRAARALDGISGRVEQITEMSLQIAAAVEEQSAVSEDI
NRNIVSIRTACELTVDEGRQSQLNSQDVAGLAGDLRSLAREFWGRRQGA

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=491, Percent_Identity=35.4378818737271, Blast_Score=258, Evalue=8e-70,
Organism=Escherichia coli, GI1787690, Length=278, Percent_Identity=32.0143884892086, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI2367378, Length=278, Percent_Identity=30.5755395683453, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788194, Length=277, Percent_Identity=32.129963898917, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788195, Length=278, Percent_Identity=29.4964028776978, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57030; Mature: 57030

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINLPVTGRNVDVAPDANILSTTDLTSAITYANDDFIRISGYSRDELLGAPHNLLRHPD
CEEECCCCCCCEECCCCCCCEEHHHHHHHHHCCCCCEEEECCCCHHHHCCCCHHHHCCCC
MPAQAFAHMWQTLKGGRSWMGLVKNRCKNGDHYWVSAYVTPVTQNGAAVEYQSVRTRPDT
CCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCEEEHHHHCCCCCH
RQIAAAERAYAQLREGRVARWPRLPSLSLRAKIMALTSSLLALVLGMEAWLRPESMGIEA
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCH
AALVAGSGACALGVGWLLRPLEHLTERARLIADNPLSQGIYTGRRDQFGQIEFALQMLEA
HHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHH
QVGAVVGRIGDASQRLAGHAAQLVDHLHSSHTSTLAQQAETDQVAAAIHQMAASVAEVAS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAQQASVAADMAGTETREGHLLVGESRSAVLRLAEELGRATEVIHQLEGHSIEISGVLEV
HHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHH
IRSIAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLAQRTQQSTNEIQRMISTLQNG
HHHHHHHCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ARDAVLVMQQSSEHVDNSVEQAQRAARALDGISGRVEQITEMSLQIAAAVEEQSAVSEDI
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRNIVSIRTACELTVDEGRQSQLNSQDVAGLAGDLRSLAREFWGRRQGA
CCCHHEEHHHHEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKINLPVTGRNVDVAPDANILSTTDLTSAITYANDDFIRISGYSRDELLGAPHNLLRHPD
CEEECCCCCCCEECCCCCCCEEHHHHHHHHHCCCCCEEEECCCCHHHHCCCCHHHHCCCC
MPAQAFAHMWQTLKGGRSWMGLVKNRCKNGDHYWVSAYVTPVTQNGAAVEYQSVRTRPDT
CCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCEEEHHHHCCCCCH
RQIAAAERAYAQLREGRVARWPRLPSLSLRAKIMALTSSLLALVLGMEAWLRPESMGIEA
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCH
AALVAGSGACALGVGWLLRPLEHLTERARLIADNPLSQGIYTGRRDQFGQIEFALQMLEA
HHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHH
QVGAVVGRIGDASQRLAGHAAQLVDHLHSSHTSTLAQQAETDQVAAAIHQMAASVAEVAS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAQQASVAADMAGTETREGHLLVGESRSAVLRLAEELGRATEVIHQLEGHSIEISGVLEV
HHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHH
IRSIAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLAQRTQQSTNEIQRMISTLQNG
HHHHHHHCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ARDAVLVMQQSSEHVDNSVEQAQRAARALDGISGRVEQITEMSLQIAAAVEEQSAVSEDI
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRNIVSIRTACELTVDEGRQSQLNSQDVAGLAGDLRSLAREFWGRRQGA
CCCHHEEHHHHEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]