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The map label for this gene is tadA [H]

Identifier: 77460805

GI number: 77460805

Start: 5180610

End: 5181107

Strand: Reverse

Name: tadA [H]

Synonym: Pfl01_4584

Alternate gene names: 77460805

Gene position: 5181107-5180610 (Counterclockwise)

Preceding gene: 77460806

Following gene: 77460796

Centisome position: 80.47

GC content: 65.26

Gene sequence:

>498_bases
ATGCGCCAGATTCGCCCCGCGGCGATCATCGACCGCAGCCGTGACCGCGACTTCATGCGCGAGGCGCTGGAGTTGGCAGC
CCAAGGCGCGGCCCTCGGCGAAGTGCCGGTGGGCGCGGTGCTGGTGCAGGATGGCGAGATCATTGGCCGTGGTTTCAACT
GCCCGATCAGCACCAGTGATCCCAGCGCGCACGCAGAAATGGTCGCGATCCGCGCTGCCGCGCAAGCGGTGGATAACTAT
CGACTGCCGGGCAGTACGCTCTACGTGACGCTCGAGCCGTGCAGCATGTGCGCCGGGCTGATCGTGCATTCGCGGGTTTC
GCGGGTGGTGTTCGGCGCGCTGGAGCCCAAGGCCGGGATTGTGCAGAGCCAGGGGCAGTTCTTCACTCAGGGCTTTCTCA
ACCATCGAGTGTTGTATGAAGGTGGGGTGTTGGCGGAGGAGTGTGGGGCGGTGTTGACCGAGTTCTTCAGGGCGCGGCGG
GCAAAACCCGCAGACTGA

Upstream 100 bases:

>100_bases
AAGTGGCGCTGGTGGCGGATAACCCCGGGGTGTGGATGTTCCACTGCCATGTGATCGACCACATGGAAACCGGCCTGATG
GCCGCCATCGAGGTGAAGTG

Downstream 100 bases:

>100_bases
AGAACAACACAAACCCTGTGGGAGCTGGCTTGCCGGCGATGGCGTCGGCACATCAAGCATTGATGTCGACTGATCCACCG
TTATCGCTGGCAAGCCAGCT

Product: tRNA-adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MRQIRPAAIIDRSRDRDFMREALELAAQGAALGEVPVGAVLVQDGEIIGRGFNCPISTSDPSAHAEMVAIRAAAQAVDNY
RLPGSTLYVTLEPCSMCAGLIVHSRVSRVVFGALEPKAGIVQSQGQFFTQGFLNHRVLYEGGVLAEECGAVLTEFFRARR
AKPAD

Sequences:

>Translated_165_residues
MRQIRPAAIIDRSRDRDFMREALELAAQGAALGEVPVGAVLVQDGEIIGRGFNCPISTSDPSAHAEMVAIRAAAQAVDNY
RLPGSTLYVTLEPCSMCAGLIVHSRVSRVVFGALEPKAGIVQSQGQFFTQGFLNHRVLYEGGVLAEECGAVLTEFFRARR
AKPAD
>Mature_165_residues
MRQIRPAAIIDRSRDRDFMREALELAAQGAALGEVPVGAVLVQDGEIIGRGFNCPISTSDPSAHAEMVAIRAAAQAVDNY
RLPGSTLYVTLEPCSMCAGLIVHSRVSRVVFGALEPKAGIVQSQGQFFTQGFLNHRVLYEGGVLAEECGAVLTEFFRARR
AKPAD

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=122, Percent_Identity=33.6065573770492, Blast_Score=70, Evalue=8e-13,
Organism=Escherichia coli, GI145693172, Length=143, Percent_Identity=51.7482517482517, Blast_Score=153, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17554608, Length=106, Percent_Identity=43.3962264150943, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=36.4864864864865, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17555996, Length=114, Percent_Identity=34.2105263157895, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=31.5068493150685, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17760; Mature: 17760

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQIRPAAIIDRSRDRDFMREALELAAQGAALGEVPVGAVLVQDGEIIGRGFNCPISTSD
CCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCC
PSAHAEMVAIRAAAQAVDNYRLPGSTLYVTLEPCSMCAGLIVHSRVSRVVFGALEPKAGI
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VQSQGQFFTQGFLNHRVLYEGGVLAEECGAVLTEFFRARRAKPAD
CCCCCHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRQIRPAAIIDRSRDRDFMREALELAAQGAALGEVPVGAVLVQDGEIIGRGFNCPISTSD
CCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCC
PSAHAEMVAIRAAAQAVDNYRLPGSTLYVTLEPCSMCAGLIVHSRVSRVVFGALEPKAGI
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VQSQGQFFTQGFLNHRVLYEGGVLAEECGAVLTEFFRARRAKPAD
CCCCCHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]