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The map label for this gene is gdhA [H]

Identifier: 77460798

GI number: 77460798

Start: 5171230

End: 5173641

Strand: Direct

Name: gdhA [H]

Synonym: Pfl01_4577

Alternate gene names: 77460798

Gene position: 5171230-5173641 (Clockwise)

Preceding gene: 77460797

Following gene: 77460799

Centisome position: 80.32

GC content: 64.26

Gene sequence:

>2412_bases
ATGAGCACTGAAGGTGCTTCGAGTCGAAGCCGTCTTCTGCCGAACCTGCTCGGCATTCTGCTTCTGCTGATGGGCCTGGC
CATGCTGGCCGGGGGAATCAAGCTGAGTACGCTCGGCGGCTCGCTGTATTACCTGCTGGCCGGTATCGGCATCACGCTGA
CCGGCATTCTGATGCTGATGCGCCGTCGCGCAGCATTGGGCCTGTACGCCATCGTGCTGTTCGCCAGCACTGTCTGGGCG
CTGTGGGAAGTTGGTCTGGACTGGTGGCAACTGGTGCCGCGTCTGGCGCTGTGGTTTGTCCTCGGTTTCGTGATGCTGCT
GCCGTGGTTCCGTCGTCCGCTGCTGCTCGCAGGCCCTGCGCCGATGGGCACCGGCGGTTTGACCGTGGCTGTGATTCTGG
CCGGCGTCACTGCCCTGGCCAGCCTGTTCACCCACCCGGGCGAAACCTTCGGCGAACTGGGTCGCGACACCGCCGACACC
ACCAGCACCGCCCCGCAAATGCCGGACGGCGACTGGCAGGCCTACGGCCGCACCGAATTCGGTGACCGCTACTCGCCACT
GAAACAGATCACCCCGGCCAACGTCGGCAAGCTGCAAGAAGCCTGGCGCATCCAGACCGGCGACCTGCCGACTGCCGACG
ACCCGGTCGAGCTGACCAACGAAAACACCCCGCTGAAAGCCAACGGCATGCTTTACGCCTGCACTGCGCACAGCAAAGTG
CTGGCACTGGACCCGGACACCGGCAAGGAACTATGGCGCTTCGATCCGCAGATCAAAAGCCCGGAAGGCTTCAAGGGCTT
CGCCCACATGACCTGCCGTGGCGTGTCGTACTACGACGAAGCCGCGTACGCCAAGTCTGAAAACGCGGCGTCCACCGTGA
TCTCCGAGGCCGGCAAAGCCGTCGCCCAGGCCTGCCCGCGTCGCCTGTACCTGCCTACCGCCGATGCCCGCCTGATCGCA
CTGAACGCCGACACCGGCAAGATCTGCGAAGGCTTCGGCACCAACGGTGTGGTTGACCTGACCCAGGGCATCGGCCCGTT
CACCGCTGGCGGTTACTACTCCACCTCTCCTGCCGCGATCACCCGTGATCTGGTGATCATGGGCGGTCACGTCACCGACA
ACGAATCGACCAACGAGCCGTCCGGCGTGATCCGCGCCTACGACGTGCGCGACGGCCATCTGGTCTGGAACTGGGACAGC
AACAACCCGGACGCCACCGAACCCTTGGCCCCGGGCCAGACCTACAGCCGCAACTCGGCCAACATGTGGTCGCTGGCCAG
CGTCGATGAAAAACTCGGCATGGTCTATCTGCCATTGGGCAACCAGACGCCTGACCAGTGGGGCGGCGATCGCACCCCCG
GTGCCGAGAAATTCAGCGCCGGCCTGGTCGCGCTGGACCTGGCGACCGGCAAGGTGCGCTGGAACTACCAGTTCACCCAC
CACGACCTGTGGGACATGGACGTCGGCAGCCAGCCAACCCTGCTGGACATGAAAACCGCCGACGGCATCAAGCCTGCGCT
GATCGCCCCGACCAAGCAGGGCAGCCTGTACGTCCTCGACCGTCGTGACGGCACGCCGATCATCCCGATCCGCGAGATCC
CGGTGCCGCAAGGCGCCGTGAAAGGCGACCACACCGCCCCGACCCAGGCCCGTTCGGACCTGAACCTGCTGGCCCCGGAA
CTGACCGAAAAAGCCATGTGGGGCGCCAGCCCGTTCGACCAGATGTTGTGCCGCATCCAGTTCAAGGAACTGCGCTACGA
AGGCCAATACACGCCTCCGTCGGAACAGGGCAGCCTGATCTACCCGGGTAACGTCGGCGTGTTCAACTGGGGCGGTGTTT
CTGTCGACCCGGTTCGCCAGATGCTGTTCACCAGCCCGAACTACATGGCTTTCGTCTCCAAGATGATCCCACGTGCCGAC
GTACCCGCCGACAGCAAGCGCGAAAGCGAAACTTCCGGCATCCAGAAAAACACCGGTGCGCCGTATGCCGTGACCATGCA
CCCGTTCATGTCGCCACTGGGCGTACCTTGCCAGGCCCCGGCCTGGGGCTACGTCGCCGGTATCGACCTGACCACCGGCA
AAGTCGTCTGGAAACGCAAAAACGGTACCAGCCGCGACAGCTCGCCAATCCCGATCGGCTTCACCCTGGGCGTGCCAAGC
ATGGGCGGCTCGATCGTCACTGCCGGCGGCGTCGGCTTCCTCAGCGGCACGCTGGACCAGTACCTGCGCGCCTACGACGT
GAACACCGGTAAAGAACTGTGGAAATCGCGTCTGCCGGCCGGCGGCCAGGCGACCCCAATGACCTACACCGGCAAGGACG
GCAAGCAATACGTCCTGCTCGTGGTGGGTGGTCACGGCTCGCTGGGCACCAAGATGGGTGACTATGTGATTGCCTACAAA
CTGCCGGAATAA

Upstream 100 bases:

>100_bases
GATAGCAAGACAAGTTTTTATCTGAACCCTGCCCGCGCCAAATCGTCATCTAAAGTGACTACAGCGCGGGACTACTTGAA
ACGTCACGGAGAACCACACT

Downstream 100 bases:

>100_bases
GCTTTAGCGGCGGTAAGGAAAAAGGCGATGCCCTGTGAGGGGTGTCGCCTTTTTTTGTGGACTGCGGTTTCTAAACGAGG
TGTTTATGTCCTACAGAAGG

Product: quinoprotein glucose dehydrogenase

Products: NA

Alternate protein names: GDH-A; Glucose dehydrogenase A [pyrroloquinoline-quinone]; Quinoprotein glucose DH [H]

Number of amino acids: Translated: 803; Mature: 802

Protein sequence:

>803_residues
MSTEGASSRSRLLPNLLGILLLLMGLAMLAGGIKLSTLGGSLYYLLAGIGITLTGILMLMRRRAALGLYAIVLFASTVWA
LWEVGLDWWQLVPRLALWFVLGFVMLLPWFRRPLLLAGPAPMGTGGLTVAVILAGVTALASLFTHPGETFGELGRDTADT
TSTAPQMPDGDWQAYGRTEFGDRYSPLKQITPANVGKLQEAWRIQTGDLPTADDPVELTNENTPLKANGMLYACTAHSKV
LALDPDTGKELWRFDPQIKSPEGFKGFAHMTCRGVSYYDEAAYAKSENAASTVISEAGKAVAQACPRRLYLPTADARLIA
LNADTGKICEGFGTNGVVDLTQGIGPFTAGGYYSTSPAAITRDLVIMGGHVTDNESTNEPSGVIRAYDVRDGHLVWNWDS
NNPDATEPLAPGQTYSRNSANMWSLASVDEKLGMVYLPLGNQTPDQWGGDRTPGAEKFSAGLVALDLATGKVRWNYQFTH
HDLWDMDVGSQPTLLDMKTADGIKPALIAPTKQGSLYVLDRRDGTPIIPIREIPVPQGAVKGDHTAPTQARSDLNLLAPE
LTEKAMWGASPFDQMLCRIQFKELRYEGQYTPPSEQGSLIYPGNVGVFNWGGVSVDPVRQMLFTSPNYMAFVSKMIPRAD
VPADSKRESETSGIQKNTGAPYAVTMHPFMSPLGVPCQAPAWGYVAGIDLTTGKVVWKRKNGTSRDSSPIPIGFTLGVPS
MGGSIVTAGGVGFLSGTLDQYLRAYDVNTGKELWKSRLPAGGQATPMTYTGKDGKQYVLLVVGGHGSLGTKMGDYVIAYK
LPE

Sequences:

>Translated_803_residues
MSTEGASSRSRLLPNLLGILLLLMGLAMLAGGIKLSTLGGSLYYLLAGIGITLTGILMLMRRRAALGLYAIVLFASTVWA
LWEVGLDWWQLVPRLALWFVLGFVMLLPWFRRPLLLAGPAPMGTGGLTVAVILAGVTALASLFTHPGETFGELGRDTADT
TSTAPQMPDGDWQAYGRTEFGDRYSPLKQITPANVGKLQEAWRIQTGDLPTADDPVELTNENTPLKANGMLYACTAHSKV
LALDPDTGKELWRFDPQIKSPEGFKGFAHMTCRGVSYYDEAAYAKSENAASTVISEAGKAVAQACPRRLYLPTADARLIA
LNADTGKICEGFGTNGVVDLTQGIGPFTAGGYYSTSPAAITRDLVIMGGHVTDNESTNEPSGVIRAYDVRDGHLVWNWDS
NNPDATEPLAPGQTYSRNSANMWSLASVDEKLGMVYLPLGNQTPDQWGGDRTPGAEKFSAGLVALDLATGKVRWNYQFTH
HDLWDMDVGSQPTLLDMKTADGIKPALIAPTKQGSLYVLDRRDGTPIIPIREIPVPQGAVKGDHTAPTQARSDLNLLAPE
LTEKAMWGASPFDQMLCRIQFKELRYEGQYTPPSEQGSLIYPGNVGVFNWGGVSVDPVRQMLFTSPNYMAFVSKMIPRAD
VPADSKRESETSGIQKNTGAPYAVTMHPFMSPLGVPCQAPAWGYVAGIDLTTGKVVWKRKNGTSRDSSPIPIGFTLGVPS
MGGSIVTAGGVGFLSGTLDQYLRAYDVNTGKELWKSRLPAGGQATPMTYTGKDGKQYVLLVVGGHGSLGTKMGDYVIAYK
LPE
>Mature_802_residues
STEGASSRSRLLPNLLGILLLLMGLAMLAGGIKLSTLGGSLYYLLAGIGITLTGILMLMRRRAALGLYAIVLFASTVWAL
WEVGLDWWQLVPRLALWFVLGFVMLLPWFRRPLLLAGPAPMGTGGLTVAVILAGVTALASLFTHPGETFGELGRDTADTT
STAPQMPDGDWQAYGRTEFGDRYSPLKQITPANVGKLQEAWRIQTGDLPTADDPVELTNENTPLKANGMLYACTAHSKVL
ALDPDTGKELWRFDPQIKSPEGFKGFAHMTCRGVSYYDEAAYAKSENAASTVISEAGKAVAQACPRRLYLPTADARLIAL
NADTGKICEGFGTNGVVDLTQGIGPFTAGGYYSTSPAAITRDLVIMGGHVTDNESTNEPSGVIRAYDVRDGHLVWNWDSN
NPDATEPLAPGQTYSRNSANMWSLASVDEKLGMVYLPLGNQTPDQWGGDRTPGAEKFSAGLVALDLATGKVRWNYQFTHH
DLWDMDVGSQPTLLDMKTADGIKPALIAPTKQGSLYVLDRRDGTPIIPIREIPVPQGAVKGDHTAPTQARSDLNLLAPEL
TEKAMWGASPFDQMLCRIQFKELRYEGQYTPPSEQGSLIYPGNVGVFNWGGVSVDPVRQMLFTSPNYMAFVSKMIPRADV
PADSKRESETSGIQKNTGAPYAVTMHPFMSPLGVPCQAPAWGYVAGIDLTTGKVVWKRKNGTSRDSSPIPIGFTLGVPSM
GGSIVTAGGVGFLSGTLDQYLRAYDVNTGKELWKSRLPAGGQATPMTYTGKDGKQYVLLVVGGHGSLGTKMGDYVIAYKL
PE

Specific function: Catalyzes an exceptionally high rate of oxidation of a wide range of aldose sugars, including D-glucose, galactose, arabinose and xylose, and also the disaccharides lactose, cellobiose and maltose [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=813, Percent_Identity=46.4944649446494, Blast_Score=711, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017511
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.99.35 [H]

Molecular weight: Translated: 86446; Mature: 86315

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEGASSRSRLLPNLLGILLLLMGLAMLAGGIKLSTLGGSLYYLLAGIGITLTGILMLM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
RRRAALGLYAIVLFASTVWALWEVGLDWWQLVPRLALWFVLGFVMLLPWFRRPLLLAGPA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
PMGTGGLTVAVILAGVTALASLFTHPGETFGELGRDTADTTSTAPQMPDGDWQAYGRTEF
CCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
GDRYSPLKQITPANVGKLQEAWRIQTGDLPTADDPVELTNENTPLKANGMLYACTAHSKV
CCCCCHHHHCCCCCHHHHHHHHEEECCCCCCCCCCCEECCCCCCEEECCEEEEEECCCEE
LALDPDTGKELWRFDPQIKSPEGFKGFAHMTCRGVSYYDEAAYAKSENAASTVISEAGKA
EEECCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHH
VAQACPRRLYLPTADARLIALNADTGKICEGFGTNGVVDLTQGIGPFTAGGYYSTSPAAI
HHHHCCCEEECCCCCCEEEEEECCCCHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCHHH
TRDLVIMGGHVTDNESTNEPSGVIRAYDVRDGHLVWNWDSNNPDATEPLAPGQTYSRNSA
EEEEEEECCEECCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
NMWSLASVDEKLGMVYLPLGNQTPDQWGGDRTPGAEKFSAGLVALDLATGKVRWNYQFTH
CEEEHHHHHHHCCEEEEECCCCCCHHCCCCCCCCHHHHCCCEEEEEEECCEEEEEEEECC
HDLWDMDVGSQPTLLDMKTADGIKPALIAPTKQGSLYVLDRRDGTPIIPIREIPVPQGAV
CCCCCCCCCCCCCEEEECCCCCCCCEEEECCCCCCEEEEECCCCCCEEEEECCCCCCCCC
KGDHTAPTQARSDLNLLAPELTEKAMWGASPFDQMLCRIQFKELRYEGQYTPPSEQGSLI
CCCCCCCCHHHCCHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
YPGNVGVFNWGGVSVDPVRQMLFTSPNYMAFVSKMIPRADVPADSKRESETSGIQKNTGA
ECCCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCC
PYAVTMHPFMSPLGVPCQAPAWGYVAGIDLTTGKVVWKRKNGTSRDSSPIPIGFTLGVPS
CEEEEECCCCCCCCCCCCCCCCCEEEEEEEECCEEEEEECCCCCCCCCCCEEEEEECCCC
MGGSIVTAGGVGFLSGTLDQYLRAYDVNTGKELWKSRLPAGGQATPMTYTGKDGKQYVLL
CCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEECCCCCEEEEE
VVGGHGSLGTKMGDYVIAYKLPE
EECCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
STEGASSRSRLLPNLLGILLLLMGLAMLAGGIKLSTLGGSLYYLLAGIGITLTGILMLM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
RRRAALGLYAIVLFASTVWALWEVGLDWWQLVPRLALWFVLGFVMLLPWFRRPLLLAGPA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
PMGTGGLTVAVILAGVTALASLFTHPGETFGELGRDTADTTSTAPQMPDGDWQAYGRTEF
CCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
GDRYSPLKQITPANVGKLQEAWRIQTGDLPTADDPVELTNENTPLKANGMLYACTAHSKV
CCCCCHHHHCCCCCHHHHHHHHEEECCCCCCCCCCCEECCCCCCEEECCEEEEEECCCEE
LALDPDTGKELWRFDPQIKSPEGFKGFAHMTCRGVSYYDEAAYAKSENAASTVISEAGKA
EEECCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHH
VAQACPRRLYLPTADARLIALNADTGKICEGFGTNGVVDLTQGIGPFTAGGYYSTSPAAI
HHHHCCCEEECCCCCCEEEEEECCCCHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCHHH
TRDLVIMGGHVTDNESTNEPSGVIRAYDVRDGHLVWNWDSNNPDATEPLAPGQTYSRNSA
EEEEEEECCEECCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
NMWSLASVDEKLGMVYLPLGNQTPDQWGGDRTPGAEKFSAGLVALDLATGKVRWNYQFTH
CEEEHHHHHHHCCEEEEECCCCCCHHCCCCCCCCHHHHCCCEEEEEEECCEEEEEEEECC
HDLWDMDVGSQPTLLDMKTADGIKPALIAPTKQGSLYVLDRRDGTPIIPIREIPVPQGAV
CCCCCCCCCCCCCEEEECCCCCCCCEEEECCCCCCEEEEECCCCCCEEEEECCCCCCCCC
KGDHTAPTQARSDLNLLAPELTEKAMWGASPFDQMLCRIQFKELRYEGQYTPPSEQGSLI
CCCCCCCCHHHCCHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
YPGNVGVFNWGGVSVDPVRQMLFTSPNYMAFVSKMIPRADVPADSKRESETSGIQKNTGA
ECCCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCC
PYAVTMHPFMSPLGVPCQAPAWGYVAGIDLTTGKVVWKRKNGTSRDSSPIPIGFTLGVPS
CEEEEECCCCCCCCCCCCCCCCCEEEEEEEECCEEEEEECCCCCCCCCCCEEEEEECCCC
MGGSIVTAGGVGFLSGTLDQYLRAYDVNTGKELWKSRLPAGGQATPMTYTGKDGKQYVLL
CCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEECCCCCEEEEE
VVGGHGSLGTKMGDYVIAYKLPE
EECCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3399393 [H]