Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 77460772

GI number: 77460772

Start: 5131154

End: 5133427

Strand: Direct

Name: yciR [C]

Synonym: Pfl01_4551

Alternate gene names: 77460772

Gene position: 5131154-5133427 (Clockwise)

Preceding gene: 77460767

Following gene: 77460773

Centisome position: 79.7

GC content: 62.14

Gene sequence:

>2274_bases
ATGAGTGCGCAACCCGGCCCTATCAACCGTCGTGTGCTGATCGTCGACGATACCGCGTCGATCCATGAGGATTTCGCGAA
AATCCTCAAGTCGGCCACAGTTACAGACGACAGTCTGGACGAAACCGAAAACCTGCTGTTCGGCGATCCGACCTCCGCTC
CCGCCGCCCCCAGGGATCCTTTCGAGCTGGACTCGGCCTATCAGGGCCGCGAAGCGCTGGACAAGGTCGAAGCCGCACTG
GCCGCGGGGCGTCCCTACGCCATGGCCTTCATCGACATGCGCATGCCGCCGGGCTGGGATGGCCTGGAAACCATCGAGCG
ACTGTGGCAGGTCGACCCCAAGCTGCAAGTGGCCCTGTGTACCGCTTATTCCGATTACTCCTGGGAGGACATTGACCAGC
GGCTGGCCCTGACCGATCGCCTGCTGATCCTGAAAAAACCCTTCGATGCGATCGAGATCCGGCAGCTGGCCAGTGCCCTG
ACGGTCAAGTGGCAGATGACCGAAGACGCCGCCATGAAGATGAACCTGCTGGAGCAGGCGGTTCAGGCGCGTACCCGGGA
ACTGTCCGACGCCAACATCATCGTGCAGAACAGCCCGACCATCCTGTACCGGCTGCGCGGCGAGCCGTCGTTTCCGTTGA
TGTACATCTCCCACAACATCACCCGATACGGGCATGTCGCGGCTGATCTGGTGGGTTCGGCCAACTGGGCGCAGACGCTG
ATTCACCCGGACGATCAGCCCAGTGTCGATGCCGCCATGGGCCGGGTGCTCGATCGCCATGCAGAGGGCGCCTCCATCGA
GTTTCGCCTGCGTACCGGCGCAGGTGACTGGCGCTGGGTGGAAAACCGCTACATCCCGGTGCGCGATCACGACGGCCGAC
TGCTGGAAGTCGAGGGGATCATTCTCGATATCACTGAACGCCGTCTGGCCGAAGAAAAGATGAACCTGCTGGCCCGCACC
GACGGTCTCACCGGGCTGGCCAATCGCGCCACCCTGATCGAGCGCCTGCATCAGGCCTTCGCCGCCGCGCGTCGGGGTGC
GGCGCCTTTTGCGGTGTTTTATCTGGATCTGGACCATTTCAAGCGGATCAACGACACCCTCGGCCATCCGGTCGGCGATT
TGCTTTTGCAGGAAGTGGCGCAGCGGATCAAATCGAATGTGCGGGAAAACGACGTAGTCGCACGGCTGGGCGGTGACGAA
TTCGCGATCCTGCAGTTGGATGTCAGCGACCCGACCCAGTCCGCCACCGTCGCCACCAAGATCCGCGATGCACTGTCGCA
GCCTTACCACTTGACGGGCAATGCCTTGCACACCTCCGTCAGTATCGGCATCTGCCTCTACCGGTCCACAAGTCTGGATG
CCGACAGCCTGCTGGCCGGCGCCGACATGGCGCTGTACCGCGCCAAGGAAACCGGGCGCAATCAGTACCAGTTCTACTCC
GAGCAAATCACCCGGGAAGTGGCCGAGCGCATTACCCTTGCCGAAGAGTTGACGACAGCGCTCATTCAGGGAGGGCTGAA
GCTCGATTACACGCCGGAAGTGGACATGCACAGCGGCAGGATTCTCGGCATGGCCGCGCAGGTCAAATGGCAACATCCCA
GGCTGGGTCTGCTGCCGGCGTCGGCCTTTGTACCGGCAGCGGAAAAGACCGGTGCAATCATCCCGCTCGGTCGCTGGATA
CTGGATCACGCCTGCTGGCAGATGCGCCAATGGCAAAACGAGGGAGTGGCGCCTCCGGTGATGGCGATCAGGATTTCCCT
GGCGCAACTCAAGAGCGGGCCCGAGCTCATCTATGACGTGCTGCGCACCACCGCCCGTTGGGAGCTGGCACCGTGGGATC
TGCGTTTCGATGTCACCGAAGCGACCCTGGCCCAGACCAAATGGACTCACAACGATGTGCTGCCGCGCCTGAGTGAGCTA
GGGGTGAAGATCGCCATCGACGATTTCGGCACCGAATACTCATCGTTCGATTACCTGAAAACCTACCGGGTCAATCACCT
CAAACTCTCCCAATCCCTGATCGACAGTGCGGCCCAGGATGAAGGCAGCGCCAATACCCTGCGCGCGATCGTCAATTTCG
CCCGGGATCTGGCGATCGACATCAGCGCCGAAGGCGTCCGGCCCACAGATCGGGATGACGCCCTGGCCTCGTCGGCACCG
CTGAAAAACGTGCAAGGCGTTTGCTTCAGGGAAGCGATCAGCCCCGAACAAGCGGCGCGTCTGCTGAAGGGCGGGAACGC
GACTGCCCCGCTGCCCAGGGAGGATGAGGGATGA

Upstream 100 bases:

>100_bases
CAAGTGGCGGGACGACACCATCGGCCTGCGCGCAGGCATGGGATGAGGGGAAAGGGATGCTCCCGATGACGAATGTGCGT
GTACAGGCGGGTATTGCGTC

Downstream 100 bases:

>100_bases
AAACACCTTTTCCCCAGACCAACCGGCGCATTCTGATCGTCGATGACACCCCGGCGATCCATGCCGACTTTCGCAAGATC
CTCACCCCGGACACCCACGG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 757; Mature: 756

Protein sequence:

>757_residues
MSAQPGPINRRVLIVDDTASIHEDFAKILKSATVTDDSLDETENLLFGDPTSAPAAPRDPFELDSAYQGREALDKVEAAL
AAGRPYAMAFIDMRMPPGWDGLETIERLWQVDPKLQVALCTAYSDYSWEDIDQRLALTDRLLILKKPFDAIEIRQLASAL
TVKWQMTEDAAMKMNLLEQAVQARTRELSDANIIVQNSPTILYRLRGEPSFPLMYISHNITRYGHVAADLVGSANWAQTL
IHPDDQPSVDAAMGRVLDRHAEGASIEFRLRTGAGDWRWVENRYIPVRDHDGRLLEVEGIILDITERRLAEEKMNLLART
DGLTGLANRATLIERLHQAFAAARRGAAPFAVFYLDLDHFKRINDTLGHPVGDLLLQEVAQRIKSNVRENDVVARLGGDE
FAILQLDVSDPTQSATVATKIRDALSQPYHLTGNALHTSVSIGICLYRSTSLDADSLLAGADMALYRAKETGRNQYQFYS
EQITREVAERITLAEELTTALIQGGLKLDYTPEVDMHSGRILGMAAQVKWQHPRLGLLPASAFVPAAEKTGAIIPLGRWI
LDHACWQMRQWQNEGVAPPVMAIRISLAQLKSGPELIYDVLRTTARWELAPWDLRFDVTEATLAQTKWTHNDVLPRLSEL
GVKIAIDDFGTEYSSFDYLKTYRVNHLKLSQSLIDSAAQDEGSANTLRAIVNFARDLAIDISAEGVRPTDRDDALASSAP
LKNVQGVCFREAISPEQAARLLKGGNATAPLPREDEG

Sequences:

>Translated_757_residues
MSAQPGPINRRVLIVDDTASIHEDFAKILKSATVTDDSLDETENLLFGDPTSAPAAPRDPFELDSAYQGREALDKVEAAL
AAGRPYAMAFIDMRMPPGWDGLETIERLWQVDPKLQVALCTAYSDYSWEDIDQRLALTDRLLILKKPFDAIEIRQLASAL
TVKWQMTEDAAMKMNLLEQAVQARTRELSDANIIVQNSPTILYRLRGEPSFPLMYISHNITRYGHVAADLVGSANWAQTL
IHPDDQPSVDAAMGRVLDRHAEGASIEFRLRTGAGDWRWVENRYIPVRDHDGRLLEVEGIILDITERRLAEEKMNLLART
DGLTGLANRATLIERLHQAFAAARRGAAPFAVFYLDLDHFKRINDTLGHPVGDLLLQEVAQRIKSNVRENDVVARLGGDE
FAILQLDVSDPTQSATVATKIRDALSQPYHLTGNALHTSVSIGICLYRSTSLDADSLLAGADMALYRAKETGRNQYQFYS
EQITREVAERITLAEELTTALIQGGLKLDYTPEVDMHSGRILGMAAQVKWQHPRLGLLPASAFVPAAEKTGAIIPLGRWI
LDHACWQMRQWQNEGVAPPVMAIRISLAQLKSGPELIYDVLRTTARWELAPWDLRFDVTEATLAQTKWTHNDVLPRLSEL
GVKIAIDDFGTEYSSFDYLKTYRVNHLKLSQSLIDSAAQDEGSANTLRAIVNFARDLAIDISAEGVRPTDRDDALASSAP
LKNVQGVCFREAISPEQAARLLKGGNATAPLPREDEG
>Mature_756_residues
SAQPGPINRRVLIVDDTASIHEDFAKILKSATVTDDSLDETENLLFGDPTSAPAAPRDPFELDSAYQGREALDKVEAALA
AGRPYAMAFIDMRMPPGWDGLETIERLWQVDPKLQVALCTAYSDYSWEDIDQRLALTDRLLILKKPFDAIEIRQLASALT
VKWQMTEDAAMKMNLLEQAVQARTRELSDANIIVQNSPTILYRLRGEPSFPLMYISHNITRYGHVAADLVGSANWAQTLI
HPDDQPSVDAAMGRVLDRHAEGASIEFRLRTGAGDWRWVENRYIPVRDHDGRLLEVEGIILDITERRLAEEKMNLLARTD
GLTGLANRATLIERLHQAFAAARRGAAPFAVFYLDLDHFKRINDTLGHPVGDLLLQEVAQRIKSNVRENDVVARLGGDEF
AILQLDVSDPTQSATVATKIRDALSQPYHLTGNALHTSVSIGICLYRSTSLDADSLLAGADMALYRAKETGRNQYQFYSE
QITREVAERITLAEELTTALIQGGLKLDYTPEVDMHSGRILGMAAQVKWQHPRLGLLPASAFVPAAEKTGAIIPLGRWIL
DHACWQMRQWQNEGVAPPVMAIRISLAQLKSGPELIYDVLRTTARWELAPWDLRFDVTEATLAQTKWTHNDVLPRLSELG
VKIAIDDFGTEYSSFDYLKTYRVNHLKLSQSLIDSAAQDEGSANTLRAIVNFARDLAIDISAEGVRPTDRDDALASSAPL
KNVQGVCFREAISPEQAARLLKGGNATAPLPREDEG

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=432, Percent_Identity=34.2592592592593, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI87081921, Length=436, Percent_Identity=26.8348623853211, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI226510982, Length=444, Percent_Identity=24.3243243243243, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=36.3636363636364, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1788381, Length=212, Percent_Identity=34.4339622641509, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI87081977, Length=166, Percent_Identity=36.144578313253, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI87081845, Length=250, Percent_Identity=27.6, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI145693134, Length=175, Percent_Identity=36.5714285714286, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI87082007, Length=158, Percent_Identity=37.9746835443038, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1786584, Length=176, Percent_Identity=32.3863636363636, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1787802, Length=169, Percent_Identity=35.5029585798817, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081881, Length=210, Percent_Identity=31.4285714285714, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790496, Length=242, Percent_Identity=26.0330578512397, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081743, Length=234, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787816, Length=180, Percent_Identity=31.6666666666667, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1788502, Length=268, Percent_Identity=23.8805970149254, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87081974, Length=108, Percent_Identity=38.8888888888889, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788956, Length=203, Percent_Identity=31.5270935960591, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1787055, Length=249, Percent_Identity=23.6947791164659, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788849, Length=236, Percent_Identity=25, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788085, Length=203, Percent_Identity=28.0788177339901, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 84054; Mature: 83923

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQPGPINRRVLIVDDTASIHEDFAKILKSATVTDDSLDETENLLFGDPTSAPAAPRDP
CCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHCCEEECCCCCCCCCCCCC
FELDSAYQGREALDKVEAALAAGRPYAMAFIDMRMPPGWDGLETIERLWQVDPKLQVALC
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEE
TAYSDYSWEDIDQRLALTDRLLILKKPFDAIEIRQLASALTVKWQMTEDAAMKMNLLEQA
EEECCCCHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHEEEEEECHHHHHHHHHHHHH
VQARTRELSDANIIVQNSPTILYRLRGEPSFPLMYISHNITRYGHVAADLVGSANWAQTL
HHHHHHCCCCCEEEEECCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHCCCCHHHHH
IHPDDQPSVDAAMGRVLDRHAEGASIEFRLRTGAGDWRWVENRYIPVRDHDGRLLEVEGI
CCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEECCCEEEEECCCCCEEEECCE
ILDITERRLAEEKMNLLARTDGLTGLANRATLIERLHQAFAAARRGAAPFAVFYLDLDHF
EEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHH
KRINDTLGHPVGDLLLQEVAQRIKSNVRENDVVARLGGDEFAILQLDVSDPTQSATVATK
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEECCCCCCHHHHHHH
IRDALSQPYHLTGNALHTSVSIGICLYRSTSLDADSLLAGADMALYRAKETGRNQYQFYS
HHHHHCCCEEECCCEEEEEEEEEEEEEECCCCCHHHHHHCCCHHHHHHHHCCCHHHHHHH
EQITREVAERITLAEELTTALIQGGLKLDYTPEVDMHSGRILGMAAQVKWQHPRLGLLPA
HHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEEEEEEEEEECCCCCCEECC
SAFVPAAEKTGAIIPLGRWILDHACWQMRQWQNEGVAPPVMAIRISLAQLKSGPELIYDV
HHCCCCHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHH
LRTTARWELAPWDLRFDVTEATLAQTKWTHNDVLPRLSELGVKIAIDDFGTEYSSFDYLK
HHHHHCCEECCCEEEEECHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCHHHH
TYRVNHLKLSQSLIDSAAQDEGSANTLRAIVNFARDLAIDISAEGVRPTDRDDALASSAP
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHCCCC
LKNVQGVCFREAISPEQAARLLKGGNATAPLPREDEG
CCCCCCHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAQPGPINRRVLIVDDTASIHEDFAKILKSATVTDDSLDETENLLFGDPTSAPAAPRDP
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHCCEEECCCCCCCCCCCCC
FELDSAYQGREALDKVEAALAAGRPYAMAFIDMRMPPGWDGLETIERLWQVDPKLQVALC
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEE
TAYSDYSWEDIDQRLALTDRLLILKKPFDAIEIRQLASALTVKWQMTEDAAMKMNLLEQA
EEECCCCHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHEEEEEECHHHHHHHHHHHHH
VQARTRELSDANIIVQNSPTILYRLRGEPSFPLMYISHNITRYGHVAADLVGSANWAQTL
HHHHHHCCCCCEEEEECCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHCCCCHHHHH
IHPDDQPSVDAAMGRVLDRHAEGASIEFRLRTGAGDWRWVENRYIPVRDHDGRLLEVEGI
CCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEECCCEEEEECCCCCEEEECCE
ILDITERRLAEEKMNLLARTDGLTGLANRATLIERLHQAFAAARRGAAPFAVFYLDLDHF
EEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHH
KRINDTLGHPVGDLLLQEVAQRIKSNVRENDVVARLGGDEFAILQLDVSDPTQSATVATK
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEECCCCCCHHHHHHH
IRDALSQPYHLTGNALHTSVSIGICLYRSTSLDADSLLAGADMALYRAKETGRNQYQFYS
HHHHHCCCEEECCCEEEEEEEEEEEEEECCCCCHHHHHHCCCHHHHHHHHCCCHHHHHHH
EQITREVAERITLAEELTTALIQGGLKLDYTPEVDMHSGRILGMAAQVKWQHPRLGLLPA
HHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEEEEEEEEEECCCCCCEECC
SAFVPAAEKTGAIIPLGRWILDHACWQMRQWQNEGVAPPVMAIRISLAQLKSGPELIYDV
HHCCCCHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHH
LRTTARWELAPWDLRFDVTEATLAQTKWTHNDVLPRLSELGVKIAIDDFGTEYSSFDYLK
HHHHHCCEECCCEEEEECHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCHHHH
TYRVNHLKLSQSLIDSAAQDEGSANTLRAIVNFARDLAIDISAEGVRPTDRDDALASSAP
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHCCCC
LKNVQGVCFREAISPEQAARLLKGGNATAPLPREDEG
CCCCCCHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]