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The map label for this gene is gltK [H]

Identifier: 77460758

GI number: 77460758

Start: 5111991

End: 5112662

Strand: Direct

Name: gltK [H]

Synonym: Pfl01_4537

Alternate gene names: 77460758

Gene position: 5111991-5112662 (Clockwise)

Preceding gene: 77460757

Following gene: 77460759

Centisome position: 79.4

GC content: 61.16

Gene sequence:

>672_bases
ATGGAATTCGATTTCAGTGGCATCGTTCCGGCCATTCCCGGCCTGTGGAACGGCATGCTGATGACCCTCAAGCTGATGGC
GCTGGGCGTGGTCGGCGGGATCATCCTCGGCACCCTCCTCGCGCTGATGCGTCTGTCCCACAGCAAACTGCTGTCGAGCA
TCGCCGGCGCGTACGTCAACTATTTCCGTTCGATCCCGCTGCTGCTGGTGATCACCTGGTTCTACCTGGCAGTGCCGTTC
GTGCTGCGCTGGATTACCGGCGAAGACACCCCGATCGGTGCGTTCACCTCGTGCATCGTGGCCTTCATGATGTTCGAAGC
GGCCTACTTCTGCGAAATCGTCCGGGCCGGCGTGCAGTCGATCCCGAAAGGCCAGATGGGCGCGGCGCAGGCACTGGGCA
TGACCTACGGCCAGATGATGCGCCTGATCATCCTGCCCCAGGCGTTCCGCAAGATGACCCCGCTGCTGCTGCAGCAGAGC
ATCATCCTGTTCCAGGACACCTCGCTGGTCTACACCGTGGGCCTGGTGGACTTCCTCAACGCCTCGCGCGCCAGTGGCGA
CATCATTGGCCGCTCGAATGAGTTCCTGATCTTCGCAGGTCTCGTGTACTTCACCATCAGCTTTGCCGCCTCGGTGCTGG
TCAAGCGTCTGCAAAAAAGGTTCGCCGTATGA

Upstream 100 bases:

>100_bases
CCCTGATCTATTTCACCCTCAACATGAGCCTGATGCTGCTGATGCGCATGGTCGAGAAGAAAGTCGCCGTGCCCGGCCTG
ATCTCCGTGGGGGGTAAATA

Downstream 100 bases:

>100_bases
TCTCTATCAAGAACATCAACAAGTGGTATGGGGACTTCCAGGTGCTGACCGATTGCAGCACCGAGGTCAAAAAGGGTGAA
GTGATCGTGGTCTGCGGTCC

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MEFDFSGIVPAIPGLWNGMLMTLKLMALGVVGGIILGTLLALMRLSHSKLLSSIAGAYVNYFRSIPLLLVITWFYLAVPF
VLRWITGEDTPIGAFTSCIVAFMMFEAAYFCEIVRAGVQSIPKGQMGAAQALGMTYGQMMRLIILPQAFRKMTPLLLQQS
IILFQDTSLVYTVGLVDFLNASRASGDIIGRSNEFLIFAGLVYFTISFAASVLVKRLQKRFAV

Sequences:

>Translated_223_residues
MEFDFSGIVPAIPGLWNGMLMTLKLMALGVVGGIILGTLLALMRLSHSKLLSSIAGAYVNYFRSIPLLLVITWFYLAVPF
VLRWITGEDTPIGAFTSCIVAFMMFEAAYFCEIVRAGVQSIPKGQMGAAQALGMTYGQMMRLIILPQAFRKMTPLLLQQS
IILFQDTSLVYTVGLVDFLNASRASGDIIGRSNEFLIFAGLVYFTISFAASVLVKRLQKRFAV
>Mature_223_residues
MEFDFSGIVPAIPGLWNGMLMTLKLMALGVVGGIILGTLLALMRLSHSKLLSSIAGAYVNYFRSIPLLLVITWFYLAVPF
VLRWITGEDTPIGAFTSCIVAFMMFEAAYFCEIVRAGVQSIPKGQMGAAQALGMTYGQMMRLIILPQAFRKMTPLLLQQS
IILFQDTSLVYTVGLVDFLNASRASGDIIGRSNEFLIFAGLVYFTISFAASVLVKRLQKRFAV

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=222, Percent_Identity=54.0540540540541, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI87082239, Length=209, Percent_Identity=35.4066985645933, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI1787030, Length=226, Percent_Identity=33.1858407079646, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786874, Length=169, Percent_Identity=32.5443786982249, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788226, Length=224, Percent_Identity=33.4821428571429, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788646, Length=227, Percent_Identity=26.8722466960352, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788645, Length=222, Percent_Identity=31.0810810810811, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI48994930, Length=135, Percent_Identity=30.3703703703704, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787087, Length=220, Percent_Identity=22.7272727272727, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1787086, Length=217, Percent_Identity=22.1198156682028, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24529; Mature: 24529

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFDFSGIVPAIPGLWNGMLMTLKLMALGVVGGIILGTLLALMRLSHSKLLSSIAGAYVN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFRSIPLLLVITWFYLAVPFVLRWITGEDTPIGAFTSCIVAFMMFEAAYFCEIVRAGVQS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPKGQMGAAQALGMTYGQMMRLIILPQAFRKMTPLLLQQSIILFQDTSLVYTVGLVDFLN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHH
ASRASGDIIGRSNEFLIFAGLVYFTISFAASVLVKRLQKRFAV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFDFSGIVPAIPGLWNGMLMTLKLMALGVVGGIILGTLLALMRLSHSKLLSSIAGAYVN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFRSIPLLLVITWFYLAVPFVLRWITGEDTPIGAFTSCIVAFMMFEAAYFCEIVRAGVQS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPKGQMGAAQALGMTYGQMMRLIILPQAFRKMTPLLLQQSIILFQDTSLVYTVGLVDFLN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHH
ASRASGDIIGRSNEFLIFAGLVYFTISFAASVLVKRLQKRFAV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]