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The map label for this gene is groES

Identifier: 77460723

GI number: 77460723

Start: 5078560

End: 5078853

Strand: Reverse

Name: groES

Synonym: Pfl01_4502

Alternate gene names: 77460723

Gene position: 5078853-5078560 (Counterclockwise)

Preceding gene: 77460724

Following gene: 77460722

Centisome position: 78.88

GC content: 57.14

Gene sequence:

>294_bases
ATGAAGCTTCGTCCTCTGCATGACCGCGTCGTCATCCGTCGCAGCGAAGAAGAAAAGAAAACCGCTGGCGGTATCGTCCT
GCCAGGTTCGGCTGCTGAAAAAGCCAACCACGGTGAGATTCTGGCTGTAGGCCCGGGCAAGGCACTGGAAAGCGGTGAAG
TGCGCGCACTGTCCGTGAAGGTAGGCGACAAGGTTGTGTTCGGTCCGTACTCCGGCAGCAACACTGTGAAAGTCGACGGC
GAAGACCTGCTGGTAATGAGCGAGAACGAAATCCTCGCCGTTATCGAAGGCTGA

Upstream 100 bases:

>100_bases
CCGCGGTTCGCTCGACGAGCCGCAACCGGCGCAGGCCGGATTCGTTAAACCCGCCGGGACTACACCGGCCGATGAAAACC
ACAATTAGGAGAGATCGACA

Downstream 100 bases:

>100_bases
TTACCCCCGTTCATTTTCCCGCTACTACAAAGTATTTAAGGAATATCGATCATGGCTGCTAAAGAAGTTAAATTCGGCGA
TTCCGCCCGCAAGAAAATGC

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 97; Mature: 97

Protein sequence:

>97_residues
MKLRPLHDRVVIRRSEEEKKTAGGIVLPGSAAEKANHGEILAVGPGKALESGEVRALSVKVGDKVVFGPYSGSNTVKVDG
EDLLVMSENEILAVIEG

Sequences:

>Translated_97_residues
MKLRPLHDRVVIRRSEEEKKTAGGIVLPGSAAEKANHGEILAVGPGKALESGEVRALSVKVGDKVVFGPYSGSNTVKVDG
EDLLVMSENEILAVIEG
>Mature_97_residues
MKLRPLHDRVVIRRSEEEKKTAGGIVLPGSAAEKANHGEILAVGPGKALESGEVRALSVKVGDKVVFGPYSGSNTVKVDG
EDLLVMSENEILAVIEG

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=57.2916666666667, Blast_Score=113, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=36.5591397849462, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324594, Length=92, Percent_Identity=41.304347826087, Blast_Score=66, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=39.1752577319588, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_PSEPF (Q3K7L5)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_350230.1
- ProteinModelPortal:   Q3K7L5
- SMR:   Q3K7L5
- STRING:   Q3K7L5
- World-2DPAGE:   0008:Q3K7L5
- GeneID:   3717761
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_4502
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   SEKIDGE
- ProtClustDB:   PRK00364
- BioCyc:   PFLU205922:PFL_4502-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10221; Mature: 10221

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRPLHDRVVIRRSEEEKKTAGGIVLPGSAAEKANHGEILAVGPGKALESGEVRALSVK
CCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEE
VGDKVVFGPYSGSNTVKVDGEDLLVMSENEILAVIEG
ECCEEEECCCCCCCEEEECCCEEEEECCCCEEEEEEC
>Mature Secondary Structure
MKLRPLHDRVVIRRSEEEKKTAGGIVLPGSAAEKANHGEILAVGPGKALESGEVRALSVK
CCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEE
VGDKVVFGPYSGSNTVKVDGEDLLVMSENEILAVIEG
ECCEEEECCCCCCCEEEECCCEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA