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The map label for this gene is hpuB [H]

Identifier: 77460600

GI number: 77460600

Start: 4934209

End: 4936794

Strand: Direct

Name: hpuB [H]

Synonym: Pfl01_4379

Alternate gene names: 77460600

Gene position: 4934209-4936794 (Clockwise)

Preceding gene: 77460599

Following gene: 77460601

Centisome position: 76.64

GC content: 62.1

Gene sequence:

>2586_bases
ATGTCCTCTCGCCTTACCCGCCAGACTTCTTCCCCTTCCCGCGTGCTGTCGCTGCTGACCGCCGCCATTCTGATGGCCGG
CACCGCGCCGCTGATGGCCGCCACCGAACAGCCGACGCGCAACATGGGCGACTACTCGTTCGCCATTCCCCAGCAGCCGC
TGGTGTCGGCGCTCAATGCGTTCACCGCGGTCACCGGCTGGCAGGTCGGTTTGCCGGCGGAACTGGGTCAGGATGTGTCG
TCGCCGGGCGTGCGCGGTTCGCTGCCACCGGAAAAAGCCCTGGAGCGCCTGTTGGTGGGGACCAACCTGAGCTTCCGCAA
ACTGAGCAACAACAACGTCGTGCTGGAAAAACGCGCCAGCAGCGGCGCACTCAATCTTGATCAGGTGACCATCAGCGCCA
CCCGTCAGGAACAGTCGATCAACAGCGTGCCGGCCACCGTCACCGTACAGACCCGTCAGGATCTGGACCGCAACAACGTC
AACACCATCAAGGATCTGGTGCGCTACGAGCCGGGCGTGTCCGTCGGCGGCGCCGGCCAGCGCGGCGGGATCAGCGGCTA
CAACATTCGCGGCATCGACGGCGACCGCATCCTGACTCAGGTCGACGGCGTCGAAGTGCCGGACGGTTTCTTCAATGGCC
CTTACGCCAAGACCCAGCGCAATTACGTTGACCCGGAAATCGTCAAGCGCGTCGAAATCCTCCGTGGCCCAGCCTCGGTG
CTGTACGGCAGCAACGCCATCGGCGGCGCGGTCAGCTACTACACCCTCGACCCGGACGACATCATCAAGCCCGGCAAAGA
CGTCGGCGCCCGCCTGAAAACCGGCTACAGCTCTGCCGACGAGAGCTGGCTGAAATCCGCCACCGTCGCCGGTCGCGCCG
ACCAGTTCGACGGCTTGCTGCACTACAGCCAGCGCGACGGTCATGAAACCGATTCCTACGGCAGCAACAACGGCACGGGC
CTGGAACGCACCGCCGCCAACCCGGAAGACGTGAAAGCCACTAACGTGCTGGCCAAGATCGGCTGGAACTACAACGAAGG
TTCGCGCCTGGGCCTGACCTACGAAAAGTACAAGGATGATCGCGACACCGATCAGAAAAGCGCCTACGGCGGCCCGTACT
TCAACGGTGCTCCGACGATCCCGAACAGCGTGCTGCCCGGCGGCATGTACCAGTGGCGCACCGGCAACGACACCATCACC
CGCGAGCGTTTCGGCCTGGAGCACAGCTTCGAGCTCGACAGCCTGCTGGCGGACAACGTGAAGTGGAGCCTCAACCACCA
GACCGCCAAGACCGACCAGAGCACCGACGAGTTCTATTACCCGATCACTCGTAAAGTCCTGCGCACCCGCGACACGATCT
ACGAAGAAAAACAGTGGGTCTTCGACGCGCAACTGGACAAGGCATTCGCCATCGGTGACACCGATCACGTGCTGACCTAC
GGCACCACGATCAAGCAGCAGAAAGTCACCGGCTCGCGCAGCGGCGACGGCAAGTGCCTGGCGGTCGGTCGCGGCTGCAC
CGCCATCGGCGCTACCAGCGCAGCCGACGTGCTGAAAAAGTCCAGCGACTTCCCGGACCCGACCATCAACACCTACAGCC
TGTTCGCCCAGGATCAGATCAGCTGGAACAACTGGACCTTCCTGCCGGGCCTGCGCTACGACTACACCCAGCTCAAGCCG
CACATCACCCAGGAATTCCTCAACACCGTGGCCGCCGACGGTAATGGCACGGTCAGTGATTCGAACAAGACATGGCATAA
AGTCTCGCCGAAATTCGGCCTGACCTACGCCCTGACCGAAAACTACACCTGGTACGGTCAGTACGCCGAAGGCTTCCGCA
CCCCGACCGCGAAAGCCCTGTACGGCCGCTTCGAGAACAGCACCACCGGCTACAACGTGGCACCGAACCCGGACCTGGAG
CCGGAAAAGAGCAAAAGCTATGAAACCGGCCTGCGCGGCAACTTCGAGCAAGGCTCGTTCGACGTGGCGGTGTTCTATAA
CAAGTACCGCGACTTCATCAACGAAGACGCCGTCACCCCTGGCTACGACGAGCTGACCTTCCAGTCGAGCAACATCAAGC
ACGCCACCATCAAGGGTGCCGAAGTCAAAGGTCGTCTGAACCTCGATTCCTTCGGCGCGCCGCAAGGCCTGTATACCCAG
GGTTCGATCTCCTACGCCTACGGACGCAACAACGACAACGGCGAGCCGTTGAACAGCGTCAACCCGCTGACCGGCGTGTT
CGGCCTCGGTTACGACCAGGACAACTACGGCGGCCTGCTGAGCTGGACCGTGGTCAAGAAGAAGGATCGCGTCGACGACA
GCAACTTCAAATCGCCGGACGGGGTCAGCAGTCAGTTCAAGACTCCGGGCTTCGGCATTCTCGATCTGGCCGGTTATTAC
AAGGTCACCGACGACGTCACCGTCAGCGGCGGCATCTACAACCTGACCGACAAGAAATACTGGCTGTGGGATGACGTGCG
CGGTTACGACAGCGTCGGCGAAGCGTCGGTGACACAACCGGCCAACCTCGATCGCCTGACCCAGCCGGGTCGCAACTTCG
CGATCAATCTGGTCTGGGATATCTGA

Upstream 100 bases:

>100_bases
AGCCAAAGCTCGTTCGTCTCGTTATAGCCAATGCAATTGATTCGCATCTCGCGAGATCAATCAGCACCTATAAAGATTCG
TGCGACACGGAGCGCTATCG

Downstream 100 bases:

>100_bases
TCCGGATGACCTCACGGCGCGCGCATGGCCGCGCCGTGAGGTTTTTTTACTGTCCGGCGCTTGCCCGTACGTCTCGTTAT
CAAGCGCCTCTTCTTTTCAA

Product: TonB-dependent hemoglobin/transferrin/lactoferrin receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 861; Mature: 860

Protein sequence:

>861_residues
MSSRLTRQTSSPSRVLSLLTAAILMAGTAPLMAATEQPTRNMGDYSFAIPQQPLVSALNAFTAVTGWQVGLPAELGQDVS
SPGVRGSLPPEKALERLLVGTNLSFRKLSNNNVVLEKRASSGALNLDQVTISATRQEQSINSVPATVTVQTRQDLDRNNV
NTIKDLVRYEPGVSVGGAGQRGGISGYNIRGIDGDRILTQVDGVEVPDGFFNGPYAKTQRNYVDPEIVKRVEILRGPASV
LYGSNAIGGAVSYYTLDPDDIIKPGKDVGARLKTGYSSADESWLKSATVAGRADQFDGLLHYSQRDGHETDSYGSNNGTG
LERTAANPEDVKATNVLAKIGWNYNEGSRLGLTYEKYKDDRDTDQKSAYGGPYFNGAPTIPNSVLPGGMYQWRTGNDTIT
RERFGLEHSFELDSLLADNVKWSLNHQTAKTDQSTDEFYYPITRKVLRTRDTIYEEKQWVFDAQLDKAFAIGDTDHVLTY
GTTIKQQKVTGSRSGDGKCLAVGRGCTAIGATSAADVLKKSSDFPDPTINTYSLFAQDQISWNNWTFLPGLRYDYTQLKP
HITQEFLNTVAADGNGTVSDSNKTWHKVSPKFGLTYALTENYTWYGQYAEGFRTPTAKALYGRFENSTTGYNVAPNPDLE
PEKSKSYETGLRGNFEQGSFDVAVFYNKYRDFINEDAVTPGYDELTFQSSNIKHATIKGAEVKGRLNLDSFGAPQGLYTQ
GSISYAYGRNNDNGEPLNSVNPLTGVFGLGYDQDNYGGLLSWTVVKKKDRVDDSNFKSPDGVSSQFKTPGFGILDLAGYY
KVTDDVTVSGGIYNLTDKKYWLWDDVRGYDSVGEASVTQPANLDRLTQPGRNFAINLVWDI

Sequences:

>Translated_861_residues
MSSRLTRQTSSPSRVLSLLTAAILMAGTAPLMAATEQPTRNMGDYSFAIPQQPLVSALNAFTAVTGWQVGLPAELGQDVS
SPGVRGSLPPEKALERLLVGTNLSFRKLSNNNVVLEKRASSGALNLDQVTISATRQEQSINSVPATVTVQTRQDLDRNNV
NTIKDLVRYEPGVSVGGAGQRGGISGYNIRGIDGDRILTQVDGVEVPDGFFNGPYAKTQRNYVDPEIVKRVEILRGPASV
LYGSNAIGGAVSYYTLDPDDIIKPGKDVGARLKTGYSSADESWLKSATVAGRADQFDGLLHYSQRDGHETDSYGSNNGTG
LERTAANPEDVKATNVLAKIGWNYNEGSRLGLTYEKYKDDRDTDQKSAYGGPYFNGAPTIPNSVLPGGMYQWRTGNDTIT
RERFGLEHSFELDSLLADNVKWSLNHQTAKTDQSTDEFYYPITRKVLRTRDTIYEEKQWVFDAQLDKAFAIGDTDHVLTY
GTTIKQQKVTGSRSGDGKCLAVGRGCTAIGATSAADVLKKSSDFPDPTINTYSLFAQDQISWNNWTFLPGLRYDYTQLKP
HITQEFLNTVAADGNGTVSDSNKTWHKVSPKFGLTYALTENYTWYGQYAEGFRTPTAKALYGRFENSTTGYNVAPNPDLE
PEKSKSYETGLRGNFEQGSFDVAVFYNKYRDFINEDAVTPGYDELTFQSSNIKHATIKGAEVKGRLNLDSFGAPQGLYTQ
GSISYAYGRNNDNGEPLNSVNPLTGVFGLGYDQDNYGGLLSWTVVKKKDRVDDSNFKSPDGVSSQFKTPGFGILDLAGYY
KVTDDVTVSGGIYNLTDKKYWLWDDVRGYDSVGEASVTQPANLDRLTQPGRNFAINLVWDI
>Mature_860_residues
SSRLTRQTSSPSRVLSLLTAAILMAGTAPLMAATEQPTRNMGDYSFAIPQQPLVSALNAFTAVTGWQVGLPAELGQDVSS
PGVRGSLPPEKALERLLVGTNLSFRKLSNNNVVLEKRASSGALNLDQVTISATRQEQSINSVPATVTVQTRQDLDRNNVN
TIKDLVRYEPGVSVGGAGQRGGISGYNIRGIDGDRILTQVDGVEVPDGFFNGPYAKTQRNYVDPEIVKRVEILRGPASVL
YGSNAIGGAVSYYTLDPDDIIKPGKDVGARLKTGYSSADESWLKSATVAGRADQFDGLLHYSQRDGHETDSYGSNNGTGL
ERTAANPEDVKATNVLAKIGWNYNEGSRLGLTYEKYKDDRDTDQKSAYGGPYFNGAPTIPNSVLPGGMYQWRTGNDTITR
ERFGLEHSFELDSLLADNVKWSLNHQTAKTDQSTDEFYYPITRKVLRTRDTIYEEKQWVFDAQLDKAFAIGDTDHVLTYG
TTIKQQKVTGSRSGDGKCLAVGRGCTAIGATSAADVLKKSSDFPDPTINTYSLFAQDQISWNNWTFLPGLRYDYTQLKPH
ITQEFLNTVAADGNGTVSDSNKTWHKVSPKFGLTYALTENYTWYGQYAEGFRTPTAKALYGRFENSTTGYNVAPNPDLEP
EKSKSYETGLRGNFEQGSFDVAVFYNKYRDFINEDAVTPGYDELTFQSSNIKHATIKGAEVKGRLNLDSFGAPQGLYTQG
SISYAYGRNNDNGEPLNSVNPLTGVFGLGYDQDNYGGLLSWTVVKKKDRVDDSNFKSPDGVSSQFKTPGFGILDLAGYYK
VTDDVTVSGGIYNLTDKKYWLWDDVRGYDSVGEASVTQPANLDRLTQPGRNFAINLVWDI

Specific function: Acts as a receptor for hemoglobin or the hemoglobin/haptoglobin complex and is required for heme uptake [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786798, Length=779, Percent_Identity=22.4646983311938, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790405, Length=144, Percent_Identity=36.1111111111111, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1790743, Length=814, Percent_Identity=21.3759213759214, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788478, Length=130, Percent_Identity=34.6153846153846, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1786344, Length=551, Percent_Identity=21.2341197822142, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010949
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 94452; Mature: 94321

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRLTRQTSSPSRVLSLLTAAILMAGTAPLMAATEQPTRNMGDYSFAIPQQPLVSALNA
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCEEEECCCHHHHHHHHH
FTAVTGWQVGLPAELGQDVSSPGVRGSLPPEKALERLLVGTNLSFRKLSNNNVVLEKRAS
HHHHCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEECCC
SGALNLDQVTISATRQEQSINSVPATVTVQTRQDLDRNNVNTIKDLVRYEPGVSVGGAGQ
CCCCEEEEEEEEEHHHHHHHCCCCCEEEEEEHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
RGGISGYNIRGIDGDRILTQVDGVEVPDGFFNGPYAKTQRNYVDPEIVKRVEILRGPASV
CCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHH
LYGSNAIGGAVSYYTLDPDDIIKPGKDVGARLKTGYSSADESWLKSATVAGRADQFDGLL
EECCCCCCCEEEEEEECHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHE
HYSQRDGHETDSYGSNNGTGLERTAANPEDVKATNVLAKIGWNYNEGSRLGLTYEKYKDD
EECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEECEEHHHHCCC
RDTDQKSAYGGPYFNGAPTIPNSVLPGGMYQWRTGNDTITRERFGLEHSFELDSLLADNV
CCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEHHHHCCCCCCCHHHHHHCCC
KWSLNHQTAKTDQSTDEFYYPITRKVLRTRDTIYEEKQWVFDAQLDKAFAIGDTDHVLTY
EEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCCEEEE
GTTIKQQKVTGSRSGDGKCLAVGRGCTAIGATSAADVLKKSSDFPDPTINTYSLFAQDQI
CCEEEHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEEECCC
SWNNWTFLPGLRYDYTQLKPHITQEFLNTVAADGNGTVSDSNKTWHKVSPKFGLTYALTE
CCCCEEECCCCCCCHHHHCHHHHHHHHHHHHCCCCCEECCCCCCEEECCCCCCEEEEEEC
NYTWYGQYAEGFRTPTAKALYGRFENSTTGYNVAPNPDLEPEKSKSYETGLRGNFEQGSF
CEEEEECHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
DVAVFYNKYRDFINEDAVTPGYDELTFQSSNIKHATIKGAEVKGRLNLDSFGAPQGLYTQ
EEEEHHHHHHHHHHHCCCCCCCHHEEEECCCCEEEEEECCEEEEEECCCCCCCCCCCEEC
GSISYAYGRNNDNGEPLNSVNPLTGVFGLGYDQDNYGGLLSWTVVKKKDRVDDSNFKSPD
CCEEEEECCCCCCCCCCCCCCCCHHHEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCC
GVSSQFKTPGFGILDLAGYYKVTDDVTVSGGIYNLTDKKYWLWDDVRGYDSVGEASVTQP
CCCCCCCCCCCCEEEECCEEEECCCEEECCCEEECCCCEEEEECCCCCCCCCCCCCCCCC
ANLDRLTQPGRNFAINLVWDI
CCCHHHCCCCCCEEEEEEEEC
>Mature Secondary Structure 
SSRLTRQTSSPSRVLSLLTAAILMAGTAPLMAATEQPTRNMGDYSFAIPQQPLVSALNA
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCEEEECCCHHHHHHHHH
FTAVTGWQVGLPAELGQDVSSPGVRGSLPPEKALERLLVGTNLSFRKLSNNNVVLEKRAS
HHHHCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEECCC
SGALNLDQVTISATRQEQSINSVPATVTVQTRQDLDRNNVNTIKDLVRYEPGVSVGGAGQ
CCCCEEEEEEEEEHHHHHHHCCCCCEEEEEEHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
RGGISGYNIRGIDGDRILTQVDGVEVPDGFFNGPYAKTQRNYVDPEIVKRVEILRGPASV
CCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHH
LYGSNAIGGAVSYYTLDPDDIIKPGKDVGARLKTGYSSADESWLKSATVAGRADQFDGLL
EECCCCCCCEEEEEEECHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHE
HYSQRDGHETDSYGSNNGTGLERTAANPEDVKATNVLAKIGWNYNEGSRLGLTYEKYKDD
EECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEECEEHHHHCCC
RDTDQKSAYGGPYFNGAPTIPNSVLPGGMYQWRTGNDTITRERFGLEHSFELDSLLADNV
CCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEHHHHCCCCCCCHHHHHHCCC
KWSLNHQTAKTDQSTDEFYYPITRKVLRTRDTIYEEKQWVFDAQLDKAFAIGDTDHVLTY
EEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCCEEEE
GTTIKQQKVTGSRSGDGKCLAVGRGCTAIGATSAADVLKKSSDFPDPTINTYSLFAQDQI
CCEEEHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEEECCC
SWNNWTFLPGLRYDYTQLKPHITQEFLNTVAADGNGTVSDSNKTWHKVSPKFGLTYALTE
CCCCEEECCCCCCCHHHHCHHHHHHHHHHHHCCCCCEECCCCCCEEECCCCCCEEEEEEC
NYTWYGQYAEGFRTPTAKALYGRFENSTTGYNVAPNPDLEPEKSKSYETGLRGNFEQGSF
CEEEEECHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
DVAVFYNKYRDFINEDAVTPGYDELTFQSSNIKHATIKGAEVKGRLNLDSFGAPQGLYTQ
EEEEHHHHHHHHHHHCCCCCCCHHEEEECCCCEEEEEECCEEEEEECCCCCCCCCCCEEC
GSISYAYGRNNDNGEPLNSVNPLTGVFGLGYDQDNYGGLLSWTVVKKKDRVDDSNFKSPD
CCEEEEECCCCCCCCCCCCCCCCHHHEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCC
GVSSQFKTPGFGILDLAGYYKVTDDVTVSGGIYNLTDKKYWLWDDVRGYDSVGEASVTQP
CCCCCCCCCCCCEEEECCEEEECCCEEECCCEEECCCCEEEEECCCCCCCCCCCCCCCCC
ANLDRLTQPGRNFAINLVWDI
CCCHHHCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]