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The map label for this gene is cefD [H]

Identifier: 77460580

GI number: 77460580

Start: 4911525

End: 4912706

Strand: Direct

Name: cefD [H]

Synonym: Pfl01_4359

Alternate gene names: 77460580

Gene position: 4911525-4912706 (Clockwise)

Preceding gene: 77460579

Following gene: 77460585

Centisome position: 76.28

GC content: 62.52

Gene sequence:

>1182_bases
ATGCCCGATAACACCCGCCGCGCCCGAGACGAAGCTTTCTGGCAAACCTTCGCCGACCGTTACGACCGCCACCCCGGCCC
GGTGAATCTGGAGAACGGCTATTTCGGGCGCATGTCGCGCACCGTGGTCGAGGAGTACCAGCGCAACATCGAGCTGATCA
ACAACAGCAACTCGATCTACGTGCGACAGCGTTTCGAGCAGCACGACAGCCTCGACATCCGCGCGCAACTGGCAGAGCTG
ATCGGCGTGCGCGCGCAAAGTGTGGCCTTCACCCACAACGCCACTGCCGGCCTGCAATCGCTGATCCGCAACTACAACCG
CCTGCAGCCTGGCGACCAGGTGCTGATCTGCGATCTGGAGTACGACACGGTCAAGGGCGCGATGCGCTGGCTGGCACAGC
ATCGCGGGGTCGAGGTGATCGAGATCGAGCACGCCCACCCCGCCAGCTTCGACAGCCTGCTGGCCACGTACCGCGAAGCC
TTCATCCGCCATCCAAAGCTCAAGCTGATGGCCCTTACTCACGTCACTCACCGTACCGGGCTGGTGATGCCGGTGCAGGC
CATTGCCGCGCTGGCCAAGGAACATGGGGTCGATATCATCCTTGATGGTGCCCATGCCCTTGGCCAGATCGAGTTCGATC
TCGAAGCGCTGGGCATCGCCTTCGCCGGGTACAACCTGCACAAGTGGATCGGCTCGCCGCTGACTCTCGGTTTTCTCTAC
ATAGCTCCACAGCGCCTGGCCGACATCGACCCGGACATGGGCGAGATGCATTTTTCGGCGGGCGATATCCGCTCACGCAC
GCCCTACAGCACGCCGAACATTCCGGCACTGATGACCCTGCCTTTGGTGTTCGAGGAACACCGCTCACTGGGTGGCGCGG
CCGCCAAGGGCGCGCGGATGAATTACCTGCGCAACCTTTGGGTGAGTGCCGTACGCAACCTGCCGGGCATTGAAGTCATG
ACCCCGGACGATCCGCGTCTGTATTGCGGCATCACCTCGATGCGTTTTACCCGGCATGCCGACCAGCAGGCGATGGTCGA
ACGCCTGCTCAACGACTACAACCTGTTCACTGTCGTGCGCAACGGCGCTGCCTGCGGGCCGTGCATCCGTGTCACGCCGT
CGCTGACCACGACGGCGGCGGAGATTCAGCAGCTGGTTCTGGCGTTGAATGAACTGCGTTAA

Upstream 100 bases:

>100_bases
TCACAACGGCCTGTCGGAACTGCTCGAACCGCTGCGCGCCAAACACGGCAAACCTGCCCCGCGCCACTGAGGCGTCACCC
TGATCCGAGTCGAGTCGACC

Downstream 100 bases:

>100_bases
ACCGTGTACTTGTCGAAGTCCTCGGGCTTGATCTGCGACGACACCGCAAAGGTGTCGATGCCGATCGTGAGGTGGCCGAA
GTACCCGTCCTCGTGTGAAT

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MPDNTRRARDEAFWQTFADRYDRHPGPVNLENGYFGRMSRTVVEEYQRNIELINNSNSIYVRQRFEQHDSLDIRAQLAEL
IGVRAQSVAFTHNATAGLQSLIRNYNRLQPGDQVLICDLEYDTVKGAMRWLAQHRGVEVIEIEHAHPASFDSLLATYREA
FIRHPKLKLMALTHVTHRTGLVMPVQAIAALAKEHGVDIILDGAHALGQIEFDLEALGIAFAGYNLHKWIGSPLTLGFLY
IAPQRLADIDPDMGEMHFSAGDIRSRTPYSTPNIPALMTLPLVFEEHRSLGGAAAKGARMNYLRNLWVSAVRNLPGIEVM
TPDDPRLYCGITSMRFTRHADQQAMVERLLNDYNLFTVVRNGAACGPCIRVTPSLTTTAAEIQQLVLALNELR

Sequences:

>Translated_393_residues
MPDNTRRARDEAFWQTFADRYDRHPGPVNLENGYFGRMSRTVVEEYQRNIELINNSNSIYVRQRFEQHDSLDIRAQLAEL
IGVRAQSVAFTHNATAGLQSLIRNYNRLQPGDQVLICDLEYDTVKGAMRWLAQHRGVEVIEIEHAHPASFDSLLATYREA
FIRHPKLKLMALTHVTHRTGLVMPVQAIAALAKEHGVDIILDGAHALGQIEFDLEALGIAFAGYNLHKWIGSPLTLGFLY
IAPQRLADIDPDMGEMHFSAGDIRSRTPYSTPNIPALMTLPLVFEEHRSLGGAAAKGARMNYLRNLWVSAVRNLPGIEVM
TPDDPRLYCGITSMRFTRHADQQAMVERLLNDYNLFTVVRNGAACGPCIRVTPSLTTTAAEIQQLVLALNELR
>Mature_392_residues
PDNTRRARDEAFWQTFADRYDRHPGPVNLENGYFGRMSRTVVEEYQRNIELINNSNSIYVRQRFEQHDSLDIRAQLAELI
GVRAQSVAFTHNATAGLQSLIRNYNRLQPGDQVLICDLEYDTVKGAMRWLAQHRGVEVIEIEHAHPASFDSLLATYREAF
IRHPKLKLMALTHVTHRTGLVMPVQAIAALAKEHGVDIILDGAHALGQIEFDLEALGIAFAGYNLHKWIGSPLTLGFLYI
APQRLADIDPDMGEMHFSAGDIRSRTPYSTPNIPALMTLPLVFEEHRSLGGAAAKGARMNYLRNLWVSAVRNLPGIEVMT
PDDPRLYCGITSMRFTRHADQQAMVERLLNDYNLFTVVRNGAACGPCIRVTPSLTTTAAEIQQLVLALNELR

Specific function: Catalyzes the reversible isomerization between isopenicillin N and penicillin N [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=353, Percent_Identity=24.0793201133144, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =5.1.1.17 [H]

Molecular weight: Translated: 44181; Mature: 44050

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDNTRRARDEAFWQTFADRYDRHPGPVNLENGYFGRMSRTVVEEYQRNIELINNSNSIY
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCEEE
VRQRFEQHDSLDIRAQLAELIGVRAQSVAFTHNATAGLQSLIRNYNRLQPGDQVLICDLE
EEEHHHCCCCHHHHHHHHHHHCCHHHHEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECC
YDTVKGAMRWLAQHRGVEVIEIEHAHPASFDSLLATYREAFIRHPKLKLMALTHVTHRTG
HHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCC
LVMPVQAIAALAKEHGVDIILDGAHALGQIEFDLEALGIAFAGYNLHKWIGSPLTLGFLY
CCHHHHHHHHHHHHCCCEEEEECCHHHCEEEECHHHHHHHHCCCCHHHHCCCCHHHHHHE
IAPQRLADIDPDMGEMHFSAGDIRSRTPYSTPNIPALMTLPLVFEEHRSLGGAAAKGARM
ECCHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCHHH
NYLRNLWVSAVRNLPGIEVMTPDDPRLYCGITSMRFTRHADQQAMVERLLNDYNLFTVVR
HHHHHHHHHHHHCCCCCEEECCCCCEEEEEEHHHHHHHCCCHHHHHHHHHCCCCEEEEEE
NGAACGPCIRVTPSLTTTAAEIQQLVLALNELR
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PDNTRRARDEAFWQTFADRYDRHPGPVNLENGYFGRMSRTVVEEYQRNIELINNSNSIY
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCEEE
VRQRFEQHDSLDIRAQLAELIGVRAQSVAFTHNATAGLQSLIRNYNRLQPGDQVLICDLE
EEEHHHCCCCHHHHHHHHHHHCCHHHHEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECC
YDTVKGAMRWLAQHRGVEVIEIEHAHPASFDSLLATYREAFIRHPKLKLMALTHVTHRTG
HHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCC
LVMPVQAIAALAKEHGVDIILDGAHALGQIEFDLEALGIAFAGYNLHKWIGSPLTLGFLY
CCHHHHHHHHHHHHCCCEEEEECCHHHCEEEECHHHHHHHHCCCCHHHHCCCCHHHHHHE
IAPQRLADIDPDMGEMHFSAGDIRSRTPYSTPNIPALMTLPLVFEEHRSLGGAAAKGARM
ECCHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCHHH
NYLRNLWVSAVRNLPGIEVMTPDDPRLYCGITSMRFTRHADQQAMVERLLNDYNLFTVVR
HHHHHHHHHHHHCCCCCEEECCCCCEEEEEEHHHHHHHCCCHHHHHHHHHCCCCEEEEEE
NGAACGPCIRVTPSLTTTAAEIQQLVLALNELR
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1694525; 2804141 [H]