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The map label for this gene is glnA [H]

Identifier: 77460480

GI number: 77460480

Start: 4804994

End: 4806337

Strand: Reverse

Name: glnA [H]

Synonym: Pfl01_4259

Alternate gene names: 77460480

Gene position: 4806337-4804994 (Counterclockwise)

Preceding gene: 77460481

Following gene: 77460479

Centisome position: 74.65

GC content: 61.09

Gene sequence:

>1344_bases
ATGACAACCGATGGCCAGCGTTCACTCGCGCAGCGATTGACGGGCATTGATGAGATTGAATGTGTCACGCCGGATTTGAA
CGGTGTGCCACGGGGCAAGGTAATGACCGCCGAGGGCTTCCTCGAAGGGCGGCGTTTGCAGTTGGCCCGAGGGGTGCTGC
TGCAATGCATCATGGGCGGCTATCCCGCCGCCAAATTCTATGGCAGCGATGACGGCGATCTGGCGCTGGTGGCCGATCCT
GCGCAGATTCACCCATTGCCATGGAGTGAAGAGCCACGGGCCTTGGCAATCTGTGATGCCGACGAGCTGACCGGCGAGAG
CTCCAACCTGTCGACCCGTGGTCAGCTCAAGAAGGTCATTGCCCGCTACGCAGCCCTCGGTCTGGCGCCGGTGGTGGCGA
CCGAACTTGAATTCTTTGTATTCGCCCCGAACACCGACCCGACCCAACCGTTCCAGCCGCCAGTCGGTCTCGACGGTCGT
CGCGAGGACGGTCATTCGGCGTTCAGCGTCAGTTCCAACAACGGTCTGCGACCGTTCTTCAGTGAAGTCTATAAATGCAT
GGCCGCCCTCGGTCTGCCGCGCGATACTTTCATGCACGAAATGGGCGTCAGCCAGTTCGAGATCAACTTGCTGCACGGTG
ATCCGCTGTTGCTGGCCGACCAGACCTTCCTGTTCAAGCACCTGCTCAAGGAAGTCGCGCTCAAGCACGGCCTGACCGTG
GTGTGCATGGCCAAGCCGCTGGCGCACACACCGGGCAGTTCGATGCACATTCACCAGAGCATCGTCGAAATCGGCAGCGG
CAAAAATGTGTTCAGCGACGCGGATGGCCAGCCGACCGCGATGTTCCGCCACTTCATCGGCGGGCAGCAGGCAGGCATGG
CTGATTTCACCGCGCTGTTTGCACCAAACGTCAATTCGTACCAGCGCCTGTGCCATCCGTTCGCGTCACCGAACAATGCC
TGCTGGTCCCACGACAACCGCGCCGCCGGCCTGCGCATTCCGGCCAGTTCGCCGGTCGCACGCCGTGTCGAGAACCGTTT
GCCGGGCGCCGATGCCAACCCGTATCTGGCCATCGCTGCGAGCCTGGCTGCCGGCTTGTACGGCATCGAGCATGAGCTGG
AACCAAGCGAAGCGATTCAGGGCGAGTTCGACGTGCCGGACCATCTTTCGCTGCCGTGTACCTTGCACGCGGCGCTCGAA
CGTCTGAAGCGCAGCCAGCTTGCAAAGGAACTGTTCGGCACGGAGTTCATCGAAGGCTACATCGCTTCGAAGACCATGGA
GTTGACCAGCTTCTTTGATGAAATCACTCCCTGGGAACGCCGTGTTCTAGCAGCCCAGGCCTGA

Upstream 100 bases:

>100_bases
CGGAATTCTTTTTGTTGGCTGCTGCTTGATATTCCGAACAGCCGAAGCCTATTTTGTCCGGGTCGCCGTTCGCGGCTCGC
ACAATAACAAGGATTGCGTC

Downstream 100 bases:

>100_bases
CGAAATGTCGCCGTCGGGCTATCGTTTGATAGCCCGATACTTACTGCAAGGAGCCGCTCGGAACGCCGATGCGCCAAATC
TGGAAATCCTTTCGAGCGCT

Product: L-glutamine synthetase

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTTDGQRSLAQRLTGIDEIECVTPDLNGVPRGKVMTAEGFLEGRRLQLARGVLLQCIMGGYPAAKFYGSDDGDLALVADP
AQIHPLPWSEEPRALAICDADELTGESSNLSTRGQLKKVIARYAALGLAPVVATELEFFVFAPNTDPTQPFQPPVGLDGR
REDGHSAFSVSSNNGLRPFFSEVYKCMAALGLPRDTFMHEMGVSQFEINLLHGDPLLLADQTFLFKHLLKEVALKHGLTV
VCMAKPLAHTPGSSMHIHQSIVEIGSGKNVFSDADGQPTAMFRHFIGGQQAGMADFTALFAPNVNSYQRLCHPFASPNNA
CWSHDNRAAGLRIPASSPVARRVENRLPGADANPYLAIAASLAAGLYGIEHELEPSEAIQGEFDVPDHLSLPCTLHAALE
RLKRSQLAKELFGTEFIEGYIASKTMELTSFFDEITPWERRVLAAQA

Sequences:

>Translated_447_residues
MTTDGQRSLAQRLTGIDEIECVTPDLNGVPRGKVMTAEGFLEGRRLQLARGVLLQCIMGGYPAAKFYGSDDGDLALVADP
AQIHPLPWSEEPRALAICDADELTGESSNLSTRGQLKKVIARYAALGLAPVVATELEFFVFAPNTDPTQPFQPPVGLDGR
REDGHSAFSVSSNNGLRPFFSEVYKCMAALGLPRDTFMHEMGVSQFEINLLHGDPLLLADQTFLFKHLLKEVALKHGLTV
VCMAKPLAHTPGSSMHIHQSIVEIGSGKNVFSDADGQPTAMFRHFIGGQQAGMADFTALFAPNVNSYQRLCHPFASPNNA
CWSHDNRAAGLRIPASSPVARRVENRLPGADANPYLAIAASLAAGLYGIEHELEPSEAIQGEFDVPDHLSLPCTLHAALE
RLKRSQLAKELFGTEFIEGYIASKTMELTSFFDEITPWERRVLAAQA
>Mature_446_residues
TTDGQRSLAQRLTGIDEIECVTPDLNGVPRGKVMTAEGFLEGRRLQLARGVLLQCIMGGYPAAKFYGSDDGDLALVADPA
QIHPLPWSEEPRALAICDADELTGESSNLSTRGQLKKVIARYAALGLAPVVATELEFFVFAPNTDPTQPFQPPVGLDGRR
EDGHSAFSVSSNNGLRPFFSEVYKCMAALGLPRDTFMHEMGVSQFEINLLHGDPLLLADQTFLFKHLLKEVALKHGLTVV
CMAKPLAHTPGSSMHIHQSIVEIGSGKNVFSDADGQPTAMFRHFIGGQQAGMADFTALFAPNVNSYQRLCHPFASPNNAC
WSHDNRAAGLRIPASSPVARRVENRLPGADANPYLAIAASLAAGLYGIEHELEPSEAIQGEFDVPDHLSLPCTLHAALER
LKRSQLAKELFGTEFIEGYIASKTMELTSFFDEITPWERRVLAAQA

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=432, Percent_Identity=25.6944444444444, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI87081870, Length=447, Percent_Identity=31.3199105145414, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1790301, Length=259, Percent_Identity=33.5907335907336, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 48579; Mature: 48448

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDGQRSLAQRLTGIDEIECVTPDLNGVPRGKVMTAEGFLEGRRLQLARGVLLQCIMGG
CCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHCC
YPAAKFYGSDDGDLALVADPAQIHPLPWSEEPRALAICDADELTGESSNLSTRGQLKKVI
CCCCEECCCCCCCEEEEECCHHCCCCCCCCCCCEEEEECHHHHCCCCCCCCHHHHHHHHH
ARYAALGLAPVVATELEFFVFAPNTDPTQPFQPPVGLDGRREDGHSAFSVSSNNGLRPFF
HHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHH
SEVYKCMAALGLPRDTFMHEMGVSQFEINLLHGDPLLLADQTFLFKHLLKEVALKHGLTV
HHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECCEEEEECHHHHHHHHHHHHHHHCCCEE
VCMAKPLAHTPGSSMHIHQSIVEIGSGKNVFSDADGQPTAMFRHFIGGQQAGMADFTALF
EEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
APNVNSYQRLCHPFASPNNACWSHDNRAAGLRIPASSPVARRVENRLPGADANPYLAIAA
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHCCCCCCCCCHHHHHH
SLAAGLYGIEHELEPSEAIQGEFDVPDHLSLPCTLHAALERLKRSQLAKELFGTEFIEGY
HHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASKTMELTSFFDEITPWERRVLAAQA
HHHHHHHHHHHHHHCCHHHHHHHHCCC
>Mature Secondary Structure 
TTDGQRSLAQRLTGIDEIECVTPDLNGVPRGKVMTAEGFLEGRRLQLARGVLLQCIMGG
CCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHCC
YPAAKFYGSDDGDLALVADPAQIHPLPWSEEPRALAICDADELTGESSNLSTRGQLKKVI
CCCCEECCCCCCCEEEEECCHHCCCCCCCCCCCEEEEECHHHHCCCCCCCCHHHHHHHHH
ARYAALGLAPVVATELEFFVFAPNTDPTQPFQPPVGLDGRREDGHSAFSVSSNNGLRPFF
HHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHH
SEVYKCMAALGLPRDTFMHEMGVSQFEINLLHGDPLLLADQTFLFKHLLKEVALKHGLTV
HHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECCEEEEECHHHHHHHHHHHHHHHCCCEE
VCMAKPLAHTPGSSMHIHQSIVEIGSGKNVFSDADGQPTAMFRHFIGGQQAGMADFTALF
EEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
APNVNSYQRLCHPFASPNNACWSHDNRAAGLRIPASSPVARRVENRLPGADANPYLAIAA
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHCCCCCCCCCHHHHHH
SLAAGLYGIEHELEPSEAIQGEFDVPDHLSLPCTLHAALERLKRSQLAKELFGTEFIEGY
HHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASKTMELTSFFDEITPWERRVLAAQA
HHHHHHHHHHHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]