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The map label for this gene is ompR [H]

Identifier: 77460466

GI number: 77460466

Start: 4787329

End: 4788051

Strand: Reverse

Name: ompR [H]

Synonym: Pfl01_4245

Alternate gene names: 77460466

Gene position: 4788051-4787329 (Counterclockwise)

Preceding gene: 77460468

Following gene: 77460465

Centisome position: 74.37

GC content: 64.45

Gene sequence:

>723_bases
GTGGAGCAAGAAGCCTGGCAGGTATTGATAGTCGAGGACGACCAGCGTCTGGCCGAACTGACCCGTGAATACCTGCAAGC
CAACGGATTGCGCGTGGAGATCGAAGGCAACGGTGCGCTGGCGGCGGCGCGGATCATCAAGGAGCAGCCGGACCTGGTGA
TCCTCGACCTGATGCTCCCCGGCGAAGACGGCCTGAGCATTTGCCGCAAGGTTCGCGATCGCTACGACGGGCCGATCCTG
ATGCTCACCGCGCGCACCGATGATGCCGACCAGATCCTCGGCCTCGACCTCGGCGCCGACGACTATGTCTGCAAACCGGT
GCGCCCACGGCTGCTGCTGGCGCGTATCCAGGCGCTGCTGCGACGCAGTGACACACTGGAGGCGCCAGCGGGCAATCCGC
GTCGGCTGCAATTCGGCCCGCTGGTGGTGGACAACGCCTTGCGTGAAGCCTGGCTCAGCGACAGTGGCATCGAGCTGACC
AGCGCCGAATTCGATCTGCTCTGGCTGCTGGTGTCCAACGCTGGACGGATCCTGTCCCGGGAAGAAATATTCACCGCACT
GCGCGGCATCGGTTACGACGGCCAGGACCGCTCGATCGATGTGCGCATCTCGCGCATCCGCCCGAAAATCGGCGACGACC
CCGATCACCCGCGCCTGATCAAGACCGTGCGCAGCAAAGGCTACCTGTTCGTGCCGGAAGCCTGCGCAGAACTGCCGCTG
TGA

Upstream 100 bases:

>100_bases
ACAATCGGCCCATGCGCACGCATTCTTATCCTCCTTAAAGATGACAAAAAGACGGGAGGATCCTTCCTTTATAGGCAGCA
TCGGCAAGCAGAGGTCACCC

Downstream 100 bases:

>100_bases
ACTCGATCTTCCTGCGCATCTATGGCGGCATGTGCGCGGCGCTGATTCTGGTGGCGGTGCTCGGTGTGCTGGCGCTGCAC
CTGCTCAACCAGGTGCGCAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MEQEAWQVLIVEDDQRLAELTREYLQANGLRVEIEGNGALAAARIIKEQPDLVILDLMLPGEDGLSICRKVRDRYDGPIL
MLTARTDDADQILGLDLGADDYVCKPVRPRLLLARIQALLRRSDTLEAPAGNPRRLQFGPLVVDNALREAWLSDSGIELT
SAEFDLLWLLVSNAGRILSREEIFTALRGIGYDGQDRSIDVRISRIRPKIGDDPDHPRLIKTVRSKGYLFVPEACAELPL

Sequences:

>Translated_240_residues
MEQEAWQVLIVEDDQRLAELTREYLQANGLRVEIEGNGALAAARIIKEQPDLVILDLMLPGEDGLSICRKVRDRYDGPIL
MLTARTDDADQILGLDLGADDYVCKPVRPRLLLARIQALLRRSDTLEAPAGNPRRLQFGPLVVDNALREAWLSDSGIELT
SAEFDLLWLLVSNAGRILSREEIFTALRGIGYDGQDRSIDVRISRIRPKIGDDPDHPRLIKTVRSKGYLFVPEACAELPL
>Mature_240_residues
MEQEAWQVLIVEDDQRLAELTREYLQANGLRVEIEGNGALAAARIIKEQPDLVILDLMLPGEDGLSICRKVRDRYDGPIL
MLTARTDDADQILGLDLGADDYVCKPVRPRLLLARIQALLRRSDTLEAPAGNPRRLQFGPLVVDNALREAWLSDSGIELT
SAEFDLLWLLVSNAGRILSREEIFTALRGIGYDGQDRSIDVRISRIRPKIGDDPDHPRLIKTVRSKGYLFVPEACAELPL

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=43.6440677966102, Blast_Score=188, Evalue=2e-49,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=43.2203389830509, Blast_Score=186, Evalue=8e-49,
Organism=Escherichia coli, GI1788394, Length=239, Percent_Identity=35.5648535564854, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=37.3333333333333, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=37.719298245614, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=33.4782608695652, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=37.3913043478261, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=35.9307359307359, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=35.5263157894737, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=32.6271186440678, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=35.3982300884956, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=32.3275862068966, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=35.8744394618834, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=34.070796460177, Blast_Score=108, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26877; Mature: 26877

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQEAWQVLIVEDDQRLAELTREYLQANGLRVEIEGNGALAAARIIKEQPDLVILDLMLP
CCCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEEEEEEC
GEDGLSICRKVRDRYDGPILMLTARTDDADQILGLDLGADDYVCKPVRPRLLLARIQALL
CCHHHHHHHHHHHHCCCCEEEEEECCCCCHHEEEEECCCCCCEECCCCHHHHHHHHHHHH
RRSDTLEAPAGNPRRLQFGPLVVDNALREAWLSDSGIELTSAEFDLLWLLVSNAGRILSR
HCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCEEECCCHHEEEEEECCCCCCCHH
EEIFTALRGIGYDGQDRSIDVRISRIRPKIGDDPDHPRLIKTVRSKGYLFVPEACAELPL
HHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCEECCHHHHCCCC
>Mature Secondary Structure
MEQEAWQVLIVEDDQRLAELTREYLQANGLRVEIEGNGALAAARIIKEQPDLVILDLMLP
CCCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEEEEEEC
GEDGLSICRKVRDRYDGPILMLTARTDDADQILGLDLGADDYVCKPVRPRLLLARIQALL
CCHHHHHHHHHHHHCCCCEEEEEECCCCCHHEEEEECCCCCCEECCCCHHHHHHHHHHHH
RRSDTLEAPAGNPRRLQFGPLVVDNALREAWLSDSGIELTSAEFDLLWLLVSNAGRILSR
HCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCEEECCCHHEEEEEECCCCCCCHH
EEIFTALRGIGYDGQDRSIDVRISRIRPKIGDDPDHPRLIKTVRSKGYLFVPEACAELPL
HHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCEECCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]