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The map label for this gene is fabA [H]

Identifier: 77460433

GI number: 77460433

Start: 4754686

End: 4755201

Strand: Direct

Name: fabA [H]

Synonym: Pfl01_4212

Alternate gene names: 77460433

Gene position: 4754686-4755201 (Clockwise)

Preceding gene: 77460432

Following gene: 77460434

Centisome position: 73.85

GC content: 60.27

Gene sequence:

>516_bases
ATGACCAAACAAAACGCCTTTACTCGGGAAGACCTGCTGCGCTGCAGTCGCGGTGAGCTGTTCGGCCCAGGTAACGCGCA
ACTGCCCGCCCCGAACATGCTGATGGTGGATCGCATCACCCTGATCAGCGAAGAAGGCGGCAAGTACGGCAAAGGTGAAT
TGGTCGCCGAGCTGGATATCAACCCTGACCTGTGGTTCTTCGCGTGCCACTTCGAAGGCGATCCGGTGATGCCGGGCTGC
CTGGGTCTGGACGCCATGTGGCAACTGGTCGGTTTCTTCCTGGGCTGGCAAGGCCTGCCGGGCCGTGGCCGTGCGCTGGG
TTCGGGCGAAGTGAAATTCTTCGGCCAGGTCCTGCCGACCGCCAAGAAAGTCACCTACAACATTCATATCAAGCGCGTCC
TCAAGGGCAAGCTGAACCTGGCCATCGCCGACGGTTCGGTGACTGTCGACGGTCGCGAAATCTACACCGCCGAAGGCCTT
CGCGTCGGCGTGTTCACCTCCACTGACAACTTCTAA

Upstream 100 bases:

>100_bases
CGCAATAGTCTATGAGTAGGCTGCCGGTTCGAGGCATGAACGCGTCGATCGGCCGGGAAGATTTGCCCCACCTGCCGCAT
GGGATTATTGAGGAGCTCGC

Downstream 100 bases:

>100_bases
GGGTTATTCGCATGCGCCGCGTCGTTATCACTGGTCTGGGCATCGTTTCGTGCCTGGGCAATGACAAAGAGACCGTCTCC
GCTAACCTGCGTGCAAGCCG

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MTKQNAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITLISEEGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGC
LGLDAMWQLVGFFLGWQGLPGRGRALGSGEVKFFGQVLPTAKKVTYNIHIKRVLKGKLNLAIADGSVTVDGREIYTAEGL
RVGVFTSTDNF

Sequences:

>Translated_171_residues
MTKQNAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITLISEEGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGC
LGLDAMWQLVGFFLGWQGLPGRGRALGSGEVKFFGQVLPTAKKVTYNIHIKRVLKGKLNLAIADGSVTVDGREIYTAEGL
RVGVFTSTDNF
>Mature_170_residues
TKQNAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITLISEEGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGCL
GLDAMWQLVGFFLGWQGLPGRGRALGSGEVKFFGQVLPTAKKVTYNIHIKRVLKGKLNLAIADGSVTVDGREIYTAEGLR
VGVFTSTDNF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=169, Percent_Identity=66.8639053254438, Blast_Score=237, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 18712; Mature: 18581

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQNAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITLISEEGGKYGKGELVAELDI
CCCCCCCCHHHHHHCCCCCEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCEEEEEEC
NPDLWFFACHFEGDPVMPGCLGLDAMWQLVGFFLGWQGLPGRGRALGSGEVKFFGQVLPT
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCC
AKKVTYNIHIKRVLKGKLNLAIADGSVTVDGREIYTAEGLRVGVFTSTDNF
CEEEEEEEEEEEEECCEEEEEEECCEEEECCCEEEEECCEEEEEEECCCCC
>Mature Secondary Structure 
TKQNAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITLISEEGGKYGKGELVAELDI
CCCCCCCHHHHHHCCCCCEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCEEEEEEC
NPDLWFFACHFEGDPVMPGCLGLDAMWQLVGFFLGWQGLPGRGRALGSGEVKFFGQVLPT
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCC
AKKVTYNIHIKRVLKGKLNLAIADGSVTVDGREIYTAEGLRVGVFTSTDNF
CEEEEEEEEEEEEECCEEEEEEECCEEEECCCEEEEECCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA