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The map label for this gene is tatD [H]

Identifier: 77460242

GI number: 77460242

Start: 4545899

End: 4546705

Strand: Direct

Name: tatD [H]

Synonym: Pfl01_4021

Alternate gene names: 77460242

Gene position: 4545899-4546705 (Clockwise)

Preceding gene: 77460238

Following gene: 77460243

Centisome position: 70.61

GC content: 62.58

Gene sequence:

>807_bases
ATGCAACTCATCGATATCGGCGTCAACCTGACCAACCCCAGTTTCGCCGACAAACACCAGGCCGTGCTCGACCGCGCCTA
CGCTGCCGGGGTCTGCCAACTGGTGCTGACCGGCACCAGCGTCGAGGGCAGCGAACAGGCGCTGGAGCTGTGCCAGCAAC
TGGATCCGGACGGCCAGCGACTGTTCGCCACCGCCGGCATTCACCCGCATTCCGCCAGCGACTGGAACGCCGACAGCGCA
AGGCGTCTGCGCAGTCTGTTGCAGGAATCGAACGTGGTGGCGGTGGGCGAATGCGGACTGGATTTCAACCGCGATTTCTC
GCCGCGCCCGCAGCAGGAAAAAGTCCTCGAAGAGCATCTGGCGCTGGCTGCCGAACTGCAACTGCCGGTGTTCCTGCATG
AACGTGATGCAAGCCAGCGCCTGCTGGAAATCCTCCGTGACTTCCGCGATCAGTTGCCGGCCGCCGTGGTGCATTGCTTT
ACCGGCGAACAGAAAGCGCTGTTCAGTTACCTCGACCTGGACCTGCACATCGGCATCACCGGCTGGATCTGCGACGAGCG
TCGCGGCACCCATTTGCATCCGCTGGTGAAGGAGATCAAGCGCGGTCGACTGATGCTCGAAAGCGATGCGCCATATCTGC
TGCCGCGCACACTGCGGCCAAAGCCGAAAAACGGGCGCAACGAGCCAGCGTACCTGACCGAAGTGTTGCGTGAAGTCGCG
TTGCATCGAGGCGAAACCGAAGCAGACCTGGCCGCCCACACAACCGCGTGCGCACGGGCGTTCTACGGTTTACCTATCCT
GCCCTGA

Upstream 100 bases:

>100_bases
CGCGGCCTCAACAGACAGCCATAAGCCGTTGTAGTTCTTGGCTTTTCTTATAAATCTACAGCTCTGATATGCTTTCCGGC
CTTCGGCCCGAGGTAGCACC

Downstream 100 bases:

>100_bases
AAGAGGCAGATGCATCGGTTGTTGATGCATATCAAGAACCGGACGCCTGGGTAGCGGCACAATAATGGCACCTTGCCAAA
ACTGTTTCCGCTATCAGAGA

Product: Sec-independent protein translocase TatD

Products: NA

Alternate protein names: DNase tatD [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MQLIDIGVNLTNPSFADKHQAVLDRAYAAGVCQLVLTGTSVEGSEQALELCQQLDPDGQRLFATAGIHPHSASDWNADSA
RRLRSLLQESNVVAVGECGLDFNRDFSPRPQQEKVLEEHLALAAELQLPVFLHERDASQRLLEILRDFRDQLPAAVVHCF
TGEQKALFSYLDLDLHIGITGWICDERRGTHLHPLVKEIKRGRLMLESDAPYLLPRTLRPKPKNGRNEPAYLTEVLREVA
LHRGETEADLAAHTTACARAFYGLPILP

Sequences:

>Translated_268_residues
MQLIDIGVNLTNPSFADKHQAVLDRAYAAGVCQLVLTGTSVEGSEQALELCQQLDPDGQRLFATAGIHPHSASDWNADSA
RRLRSLLQESNVVAVGECGLDFNRDFSPRPQQEKVLEEHLALAAELQLPVFLHERDASQRLLEILRDFRDQLPAAVVHCF
TGEQKALFSYLDLDLHIGITGWICDERRGTHLHPLVKEIKRGRLMLESDAPYLLPRTLRPKPKNGRNEPAYLTEVLREVA
LHRGETEADLAAHTTACARAFYGLPILP
>Mature_268_residues
MQLIDIGVNLTNPSFADKHQAVLDRAYAAGVCQLVLTGTSVEGSEQALELCQQLDPDGQRLFATAGIHPHSASDWNADSA
RRLRSLLQESNVVAVGECGLDFNRDFSPRPQQEKVLEEHLALAAELQLPVFLHERDASQRLLEILRDFRDQLPAAVVHCF
TGEQKALFSYLDLDLHIGITGWICDERRGTHLHPLVKEIKRGRLMLESDAPYLLPRTLRPKPKNGRNEPAYLTEVLREVA
LHRGETEADLAAHTTACARAFYGLPILP

Specific function: Shows DNase activity [H]

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=286, Percent_Identity=33.9160839160839, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI225903439, Length=242, Percent_Identity=33.0578512396694, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI225903424, Length=183, Percent_Identity=31.6939890710383, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI48994985, Length=262, Percent_Identity=45.4198473282443, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1787342, Length=267, Percent_Identity=29.9625468164794, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87082439, Length=213, Percent_Identity=31.924882629108, Blast_Score=91, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17559024, Length=284, Percent_Identity=37.3239436619718, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17543026, Length=171, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17565396, Length=170, Percent_Identity=32.3529411764706, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24648690, Length=286, Percent_Identity=33.5664335664336, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI221330018, Length=293, Percent_Identity=31.740614334471, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24586117, Length=262, Percent_Identity=30.9160305343511, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29879; Mature: 29879

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLIDIGVNLTNPSFADKHQAVLDRAYAAGVCQLVLTGTSVEGSEQALELCQQLDPDGQR
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCE
LFATAGIHPHSASDWNADSARRLRSLLQESNVVAVGECGLDFNRDFSPRPQQEKVLEEHL
EEEECCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHH
ALAAELQLPVFLHERDASQRLLEILRDFRDQLPAAVVHCFTGEQKALFSYLDLDLHIGIT
HHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCEEEEECEE
GWICDERRGTHLHPLVKEIKRGRLMLESDAPYLLPRTLRPKPKNGRNEPAYLTEVLREVA
EEEECCCCCCCHHHHHHHHHHCCEEEECCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHH
LHRGETEADLAAHTTACARAFYGLPILP
HHCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQLIDIGVNLTNPSFADKHQAVLDRAYAAGVCQLVLTGTSVEGSEQALELCQQLDPDGQR
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCE
LFATAGIHPHSASDWNADSARRLRSLLQESNVVAVGECGLDFNRDFSPRPQQEKVLEEHL
EEEECCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHH
ALAAELQLPVFLHERDASQRLLEILRDFRDQLPAAVVHCFTGEQKALFSYLDLDLHIGIT
HHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCEEEEECEE
GWICDERRGTHLHPLVKEIKRGRLMLESDAPYLLPRTLRPKPKNGRNEPAYLTEVLREVA
EEEECCCCCCCHHHHHHHHHHCCEEEECCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHH
LHRGETEADLAAHTTACARAFYGLPILP
HHCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584020; 9649434; 1379743; 9278503; 10747959 [H]