Click here to switch to the map view.

The map label for this gene is galE [H]

Identifier: 77460056

GI number: 77460056

Start: 4336139

End: 4337167

Strand: Reverse

Name: galE [H]

Synonym: Pfl01_3834

Alternate gene names: 77460056

Gene position: 4337167-4336139 (Counterclockwise)

Preceding gene: 77460058

Following gene: 77460055

Centisome position: 67.36

GC content: 62.78

Gene sequence:

>1029_bases
ATGGACCGCGCTATGAAGATTCTGGTAACGGGTGGCGCCGGCTATATCGGCTCGCACACCACACTTGCACTACTTGAAGC
AGGTTATGAAGTTGTAGTTCTGGATAATCTTTGCAACAGCAGCGACGCCGCCTTGCACGCGGTGGAAGCCATTTGCGGCA
AAAGTGCGCTGATGATTCGCGGGGATGTCTGTGACCGGGCCCTGCTGGACCGGATTTTCCAGCAGCACGCCATCGATGCC
GTGCTGCACTTCGCCGGGCTCAAGGCTGTCGGCGAGAGCGTGCGCAAGCCGCTCGAGTACTACGAAACCAACGTCAGCGG
CAGCATCACGCTGTGCCAGGCAATGGCAGCGGCGGGGGTGTTCCGGCTGGTGTTCAGCTCGTCCGCCACGGTCTACGGCG
AGCCGGCGCAGATGCCGATCCGCGAGGATTTCCCGACCGGCACTCCGACCAATCCCTACGGCCAGTCCAAGCTGATCGTC
GAGAACGTGCTGCGCGACCTGTGCCAGTCCGAACCGCGCTGGAGCATCGCGCTGCTGCGCTACTTCAACCCGATCGGCGC
GCATCACAGCGGCCAGATGGGCGAAGACCCCAACGGCATTCCGAACAATCTGGTGCCTTACATCAGCCAGGTGGCGGTCG
GCAGCCTCAAGGAGTTGTCGATCTTCGGCGACGATTACCCGACGGTCGACGGCACCGGCGTACGTGATTACATCCACGTC
GTCGACCTGGCGGACGGGCACCTGAAAGCCCTGCAAGCCATCGCCGACCGTACCGGCATTCATACCTGGAACCTCGGCAC
CGGCGACGGCTACAGCGTGTTGCAGGTACTGCGGGCTTTCGAACAGGCCTGTGGGCAGCCGGTGCCTTACCGGGTGATGC
CACGGCGTTCCGGGGATATTGCCGAGAGCTGGGCCGACGCCTCCAAGGCGGCGAAGGAGCTCGGCTGGAAAGCCACGCGC
AACTTGCAGGACATGGTCACCGACACCTGGCGCTGGCAATCGAATCATCCCCGGGGTTATCAGGGATGA

Upstream 100 bases:

>100_bases
TGAACTGTTTTTGTTTCTGGTTGTTGTCGCGCTGTTTGTGTGAATCAAGACACACATTAAACAAACAGCGCTTGACACGC
GAGTTGGCACTTTTCCCACT

Downstream 100 bases:

>100_bases
TGGCGTTTTAGTGCAATGTTAGTTTCAGTCAGGTTGTTAGATATCGTCGGGAAATTAGACTGGCAATGCCTTTTGCAAGT
CCGTAGATATAAACCTGCCG

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MDRAMKILVTGGAGYIGSHTTLALLEAGYEVVVLDNLCNSSDAALHAVEAICGKSALMIRGDVCDRALLDRIFQQHAIDA
VLHFAGLKAVGESVRKPLEYYETNVSGSITLCQAMAAAGVFRLVFSSSATVYGEPAQMPIREDFPTGTPTNPYGQSKLIV
ENVLRDLCQSEPRWSIALLRYFNPIGAHHSGQMGEDPNGIPNNLVPYISQVAVGSLKELSIFGDDYPTVDGTGVRDYIHV
VDLADGHLKALQAIADRTGIHTWNLGTGDGYSVLQVLRAFEQACGQPVPYRVMPRRSGDIAESWADASKAAKELGWKATR
NLQDMVTDTWRWQSNHPRGYQG

Sequences:

>Translated_342_residues
MDRAMKILVTGGAGYIGSHTTLALLEAGYEVVVLDNLCNSSDAALHAVEAICGKSALMIRGDVCDRALLDRIFQQHAIDA
VLHFAGLKAVGESVRKPLEYYETNVSGSITLCQAMAAAGVFRLVFSSSATVYGEPAQMPIREDFPTGTPTNPYGQSKLIV
ENVLRDLCQSEPRWSIALLRYFNPIGAHHSGQMGEDPNGIPNNLVPYISQVAVGSLKELSIFGDDYPTVDGTGVRDYIHV
VDLADGHLKALQAIADRTGIHTWNLGTGDGYSVLQVLRAFEQACGQPVPYRVMPRRSGDIAESWADASKAAKELGWKATR
NLQDMVTDTWRWQSNHPRGYQG
>Mature_342_residues
MDRAMKILVTGGAGYIGSHTTLALLEAGYEVVVLDNLCNSSDAALHAVEAICGKSALMIRGDVCDRALLDRIFQQHAIDA
VLHFAGLKAVGESVRKPLEYYETNVSGSITLCQAMAAAGVFRLVFSSSATVYGEPAQMPIREDFPTGTPTNPYGQSKLIV
ENVLRDLCQSEPRWSIALLRYFNPIGAHHSGQMGEDPNGIPNNLVPYISQVAVGSLKELSIFGDDYPTVDGTGVRDYIHV
VDLADGHLKALQAIADRTGIHTWNLGTGDGYSVLQVLRAFEQACGQPVPYRVMPRRSGDIAESWADASKAAKELGWKATR
NLQDMVTDTWRWQSNHPRGYQG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=55.3935860058309, Blast_Score=398, Evalue=1e-111,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=55.3935860058309, Blast_Score=398, Evalue=1e-111,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=55.3935860058309, Blast_Score=398, Evalue=1e-111,
Organism=Homo sapiens, GI7657641, Length=349, Percent_Identity=26.647564469914, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=60.7142857142857, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI48994969, Length=354, Percent_Identity=28.5310734463277, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788353, Length=365, Percent_Identity=26.3013698630137, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=49.8550724637681, Blast_Score=353, Evalue=6e-98,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=48.9913544668588, Blast_Score=353, Evalue=9e-98,
Organism=Caenorhabditis elegans, GI17568069, Length=339, Percent_Identity=23.0088495575221, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115532424, Length=334, Percent_Identity=23.9520958083832, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=50.2906976744186, Blast_Score=351, Evalue=8e-98,
Organism=Drosophila melanogaster, GI19923002, Length=342, Percent_Identity=56.4327485380117, Blast_Score=412, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37207; Mature: 37207

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRAMKILVTGGAGYIGSHTTLALLEAGYEVVVLDNLCNSSDAALHAVEAICGKSALMIR
CCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEE
GDVCDRALLDRIFQQHAIDAVLHFAGLKAVGESVRKPLEYYETNVSGSITLCQAMAAAGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FRLVFSSSATVYGEPAQMPIREDFPTGTPTNPYGQSKLIVENVLRDLCQSEPRWSIALLR
HHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
YFNPIGAHHSGQMGEDPNGIPNNLVPYISQVAVGSLKELSIFGDDYPTVDGTGVRDYIHV
HHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHEEECCCCCCCCCCCHHHHHHE
VDLADGHLKALQAIADRTGIHTWNLGTGDGYSVLQVLRAFEQACGQPVPYRVMPRRSGDI
EECCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCH
AESWADASKAAKELGWKATRNLQDMVTDTWRWQSNHPRGYQG
HHHHHHHHHHHHHHCCHHHCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDRAMKILVTGGAGYIGSHTTLALLEAGYEVVVLDNLCNSSDAALHAVEAICGKSALMIR
CCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEE
GDVCDRALLDRIFQQHAIDAVLHFAGLKAVGESVRKPLEYYETNVSGSITLCQAMAAAGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FRLVFSSSATVYGEPAQMPIREDFPTGTPTNPYGQSKLIVENVLRDLCQSEPRWSIALLR
HHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
YFNPIGAHHSGQMGEDPNGIPNNLVPYISQVAVGSLKELSIFGDDYPTVDGTGVRDYIHV
HHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHEEECCCCCCCCCCCHHHHHHE
VDLADGHLKALQAIADRTGIHTWNLGTGDGYSVLQVLRAFEQACGQPVPYRVMPRRSGDI
EECCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCH
AESWADASKAAKELGWKATRNLQDMVTDTWRWQSNHPRGYQG
HHHHHHHHHHHHHHCCHHHCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3022232; 8905232; 9278503; 2134186; 8564363; 6301942; 1579570; 8611559; 8931134; 9174344; 9271499; 9708982 [H]