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The map label for this gene is uppP2

Identifier: 77460048

GI number: 77460048

Start: 4325785

End: 4326618

Strand: Reverse

Name: uppP2

Synonym: Pfl01_3826

Alternate gene names: 77460048

Gene position: 4326618-4325785 (Counterclockwise)

Preceding gene: 77460052

Following gene: 77460038

Centisome position: 67.2

GC content: 58.03

Gene sequence:

>834_bases
ATGGATTTACTGACCTTGTTCAAGGTGCTGATTCTTGGGGCGGTAGAAGGCTTGACCGAGTTCCTGCCCATTTCCAGTAC
GGGCCACCAGATTATTGTTGCCGACTTGCTGGAATTTGGTGGGGAACGTGCCATGGCGTTCAATATCATCATTCAACTGG
GCGCCATTCTGGCGGTGGTCTGGGAGTTTCGCCCGAAAATCTTCGAGATCGTCAAAGGCCTGCCGACCCAGAGCAATGCA
CAGCGTTTTACCCGTAATCTACTGATCGCTTTTTTCCCGGCGGTGATTCTCGGCGTGTTATTCGCCGACACGATTCATGA
ATACCTGTTCAACCCGATCACCGTTGCCGTCGCATTGGTCGTGGGCGGCATCGTGATGTTGTGGGCCGAGCAGCGCGATC
ATGTAGTGAGTGTCGACCATGTGGACGACATGAAGTGGGCCGACGCGCTGAAGATCGGTTGCGTCCAGTGCCTGGCGATG
ATTCCGGGCACGTCGCGCTCCGGTTCCACCATCATCGGCGGTCTGCTGTTCGGCCTGTCACGCAAGGCCGCCACGGAGTT
CTCGTTCTTCCTGGCAATGCCGACCATGGTCGGTGCCGCGGTTTATTCCGGCTACAAGTACCGCGAACTGTTCCAGAGCA
GCGACCTGCCGGTCTTCGCCCTGGGCTTCGTCGTAGCGTTCATCTTCGCGATGATCGCCGTGCGCGGCCTGCTGAAGTTC
ATTGCGAACCACAGCTACGCCACCTTCGCCTGGTACCGCATCGCCTTCGGCTTGCTGATCCTTGCCACGTGGCAATTTGG
TTGGGTCAACTGGACGGCGGCCGCAGCCGCTTGA

Upstream 100 bases:

>100_bases
CGGGCAATGGGTGCGCATCTGCCAATTGTTTTACTTCAGATACTCAATGCCTGAATGCATTTAACAGGGCGCCCGCAAAG
AGCGCTCTGACGGAGGATTA

Downstream 100 bases:

>100_bases
TCACTGACTGCTGATCAGCGCAGCGACGGCGAGGTCATTCAATTCAGAGTCGGGCGAGTCCTGACGAAACCGCTGCAACG
CCGAGGTGAAATACGCGGCT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 2; Undecaprenyl pyrophosphate phosphatase 2

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MDLLTLFKVLILGAVEGLTEFLPISSTGHQIIVADLLEFGGERAMAFNIIIQLGAILAVVWEFRPKIFEIVKGLPTQSNA
QRFTRNLLIAFFPAVILGVLFADTIHEYLFNPITVAVALVVGGIVMLWAEQRDHVVSVDHVDDMKWADALKIGCVQCLAM
IPGTSRSGSTIIGGLLFGLSRKAATEFSFFLAMPTMVGAAVYSGYKYRELFQSSDLPVFALGFVVAFIFAMIAVRGLLKF
IANHSYATFAWYRIAFGLLILATWQFGWVNWTAAAAA

Sequences:

>Translated_277_residues
MDLLTLFKVLILGAVEGLTEFLPISSTGHQIIVADLLEFGGERAMAFNIIIQLGAILAVVWEFRPKIFEIVKGLPTQSNA
QRFTRNLLIAFFPAVILGVLFADTIHEYLFNPITVAVALVVGGIVMLWAEQRDHVVSVDHVDDMKWADALKIGCVQCLAM
IPGTSRSGSTIIGGLLFGLSRKAATEFSFFLAMPTMVGAAVYSGYKYRELFQSSDLPVFALGFVVAFIFAMIAVRGLLKF
IANHSYATFAWYRIAFGLLILATWQFGWVNWTAAAAA
>Mature_277_residues
MDLLTLFKVLILGAVEGLTEFLPISSTGHQIIVADLLEFGGERAMAFNIIIQLGAILAVVWEFRPKIFEIVKGLPTQSNA
QRFTRNLLIAFFPAVILGVLFADTIHEYLFNPITVAVALVVGGIVMLWAEQRDHVVSVDHVDDMKWADALKIGCVQCLAM
IPGTSRSGSTIIGGLLFGLSRKAATEFSFFLAMPTMVGAAVYSGYKYRELFQSSDLPVFALGFVVAFIFAMIAVRGLLKF
IANHSYATFAWYRIAFGLLILATWQFGWVNWTAAAAA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=260, Percent_Identity=48.4615384615385, Blast_Score=222, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP2_PSEPF (Q3K9J0)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_349555.1
- STRING:   Q3K9J0
- GeneID:   3714854
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_3826
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   ADTIHEY
- ProtClustDB:   PRK12554
- BioCyc:   PFLU205922:PFL_3826-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30394; Mature: 30394

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x136a692c)-; HASH(0x137f48a0)-; HASH(0x136a6fac)-; HASH(0x137f4930)-; HASH(0x134c1460)-; HASH(0x139c5c68)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHCH
>Mature Secondary Structure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HHCCCHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA