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The map label for this gene is blh [H]

Identifier: 77459682

GI number: 77459682

Start: 3944804

End: 3945667

Strand: Direct

Name: blh [H]

Synonym: Pfl01_3460

Alternate gene names: 77459682

Gene position: 3944804-3945667 (Clockwise)

Preceding gene: 77459678

Following gene: 77459683

Centisome position: 61.27

GC content: 60.88

Gene sequence:

>864_bases
ATGCCCGCGCTGATTGAAGCTTTCCTCGACCCCGCCTCTTCGACCTACAGCTATGTGGTCTACGAGGCCGATGGCGGGCA
ATGCGCAATCGTCGATCCGGTGCTCGATTACGACGGGGCCGCCGGCCGCACCTGCACGGCTCAGGCCGACAGGATCATCG
CCTTCGTGCATGCCCATCACTTGCAAGTGCAATGGCTGCTGGAAACCCATGCCCACGCCGACCACCTGTCCGCCGCGCCC
TACCTGCGCCGGGAACTGGGCGGGAAAATCGCCATTGGCGAATCGATCAGCAAAGTGCAGAACGTGTTCAAGGCGCTGTT
CAACCTGGAACCGGAATTTCGCGTCGACGGCTCGCAGTTCGATCATCTGTTCGCGCCGAACGAGTCGTTCCGGATCGGCA
ATCTCAAGGCCACCGCCCTGCATGTCCCCGGCCACACCCCGGCGGACATGGCCTACTTGATCGACGGCGAACAGATCCTG
GTCGGCGACACGCTGTTCATGCCCGACGTCGGCACCGCCCGTTGCGACTTCCCAGGTGGCAACGCCCATCAGTTGTTCAA
TTCGATTCACAAGCTGCTGGCCTTCCCTGCCAGCGTGAAGCTCTATGTCTGCCACGACTATCCGCCGCAAGGCCGCGACT
CGCAGTGCCAGACCACCGTGGGTGAACAGCGCAAAAGCAATATCCATGTGCATGACGGCGTCGATGAGGCCGCGTTTGTC
GAGATGCGTACCAAACGGGATGCCGGACTTGGAATGCCGACACTGTTGTTGCCGGCGATTCAGGTGAATGTGCGGGCGGG
AAATCTGCCACCGGCGGAAGGCAATGGCGTTGTTTACCTGAAGATCCCTATCAACTCCGTGTAA

Upstream 100 bases:

>100_bases
ATTTGCAGGATGCCTTCAACGTCACTTAAGCTGCGGACATTATGTGTTTACATAAAGTGTTGCAACTCTGACTTTCCACC
TTCTGCACAGGACCGTGTCC

Downstream 100 bases:

>100_bases
GAAAAAATCATTGAGGGAACTCAAAACAAGAGTATTCGTACCTGTCACGTCGAATGCCATGAGCTGGGCGTAATCTCCGC
GGGCAGGCAGACTTCATTGG

Product: beta-lactamase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MPALIEAFLDPASSTYSYVVYEADGGQCAIVDPVLDYDGAAGRTCTAQADRIIAFVHAHHLQVQWLLETHAHADHLSAAP
YLRRELGGKIAIGESISKVQNVFKALFNLEPEFRVDGSQFDHLFAPNESFRIGNLKATALHVPGHTPADMAYLIDGEQIL
VGDTLFMPDVGTARCDFPGGNAHQLFNSIHKLLAFPASVKLYVCHDYPPQGRDSQCQTTVGEQRKSNIHVHDGVDEAAFV
EMRTKRDAGLGMPTLLLPAIQVNVRAGNLPPAEGNGVVYLKIPINSV

Sequences:

>Translated_287_residues
MPALIEAFLDPASSTYSYVVYEADGGQCAIVDPVLDYDGAAGRTCTAQADRIIAFVHAHHLQVQWLLETHAHADHLSAAP
YLRRELGGKIAIGESISKVQNVFKALFNLEPEFRVDGSQFDHLFAPNESFRIGNLKATALHVPGHTPADMAYLIDGEQIL
VGDTLFMPDVGTARCDFPGGNAHQLFNSIHKLLAFPASVKLYVCHDYPPQGRDSQCQTTVGEQRKSNIHVHDGVDEAAFV
EMRTKRDAGLGMPTLLLPAIQVNVRAGNLPPAEGNGVVYLKIPINSV
>Mature_286_residues
PALIEAFLDPASSTYSYVVYEADGGQCAIVDPVLDYDGAAGRTCTAQADRIIAFVHAHHLQVQWLLETHAHADHLSAAPY
LRRELGGKIAIGESISKVQNVFKALFNLEPEFRVDGSQFDHLFAPNESFRIGNLKATALHVPGHTPADMAYLIDGEQILV
GDTLFMPDVGTARCDFPGGNAHQLFNSIHKLLAFPASVKLYVCHDYPPQGRDSQCQTTVGEQRKSNIHVHDGVDEAAFVE
MRTKRDAGLGMPTLLLPAIQVNVRAGNLPPAEGNGVVYLKIPINSV

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=273, Percent_Identity=26.007326007326, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538952, Length=266, Percent_Identity=26.3157894736842, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI221330176, Length=241, Percent_Identity=27.8008298755187, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 31205; Mature: 31074

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALIEAFLDPASSTYSYVVYEADGGQCAIVDPVLDYDGAAGRTCTAQADRIIAFVHAHH
CCHHHHHHHCCCCCCEEEEEEECCCCEEEEECCEECCCCCCCCEEECCCCCEEEEEEHHE
LQVQWLLETHAHADHLSAAPYLRRELGGKIAIGESISKVQNVFKALFNLEPEFRVDGSQF
EEEEEEEHHCCCHHHCCCCHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCCCEEECCCCC
DHLFAPNESFRIGNLKATALHVPGHTPADMAYLIDGEQILVGDTLFMPDVGTARCDFPGG
CEEECCCCCEEECCEEEEEEECCCCCCCCEEEEECCCEEEEECEEECCCCCCCEECCCCC
NAHQLFNSIHKLLAFPASVKLYVCHDYPPQGRDSQCQTTVGEQRKSNIHVHDGVDEAAFV
CHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCEEEECCCCCHHEE
EMRTKRDAGLGMPTLLLPAIQVNVRAGNLPPAEGNGVVYLKIPINSV
EEHHCCCCCCCCHHHEEEEEEEEEEECCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
PALIEAFLDPASSTYSYVVYEADGGQCAIVDPVLDYDGAAGRTCTAQADRIIAFVHAHH
CHHHHHHHCCCCCCEEEEEEECCCCEEEEECCEECCCCCCCCEEECCCCCEEEEEEHHE
LQVQWLLETHAHADHLSAAPYLRRELGGKIAIGESISKVQNVFKALFNLEPEFRVDGSQF
EEEEEEEHHCCCHHHCCCCHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCCCEEECCCCC
DHLFAPNESFRIGNLKATALHVPGHTPADMAYLIDGEQILVGDTLFMPDVGTARCDFPGG
CEEECCCCCEEECCEEEEEEECCCCCCCCEEEEECCCEEEEECEEECCCCCCCEECCCCC
NAHQLFNSIHKLLAFPASVKLYVCHDYPPQGRDSQCQTTVGEQRKSNIHVHDGVDEAAFV
CHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCEEEECCCCCHHEE
EMRTKRDAGLGMPTLLLPAIQVNVRAGNLPPAEGNGVVYLKIPINSV
EEHHCCCCCCCCHHHEEEEEEEEEEECCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]