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The map label for this gene is ygfU [H]

Identifier: 77459655

GI number: 77459655

Start: 3914373

End: 3915728

Strand: Direct

Name: ygfU [H]

Synonym: Pfl01_3433

Alternate gene names: 77459655

Gene position: 3914373-3915728 (Clockwise)

Preceding gene: 77459654

Following gene: 77459656

Centisome position: 60.8

GC content: 64.09

Gene sequence:

>1356_bases
ATGTCGTCAGCCAGTTCCTCCTCCACCGTCCACCCTGTCGACCGCGTCCTGCCGGTGCGACAGATGCTCACCCTCGGCCT
GCAGCACATGGCCGTCTCGTACATCGGCGCCATCGCAGTGCCGTTGATTGTTGCCAGTGCCCTGAAGATGTCCCACGCCG
ACACGGTGGTGCTGATCAGCACCACGCTGTTCTGCTCCGGCATCGCCACCCTGTTGCAGACCGTCGGTTTCTGGAGGTTC
GGCGTGCGCCTGCCGATCCTGCAAGGCGTGGCGTTCAGCAGCGTCGGGCCGGTGATCGCCATCGGCAGCAACCCGGAGGT
GGGATTCGCCGGGGTCTGCGGGGCGGTGATCGGCGCGGGAATTTTCACCATGCTGATCGCACCGTTCGTGGGCCGCTTGC
GACGGTTTTTCCCACCGGTGGTGACCGGCTGTATCGTCACGGTGATCGGTTTGCAGCTGTTCCCGATTGCCTATGAATGG
GTCGGTGGCGGGCGCAACGCGAGCAATTTCGGCGCCCCGGCGTTTCTCGCCGTGGCGGTGGTGGTGTTGCTGACCATCCT
GCTGGTCAACCGCTATGGCAGCCCGCTGCTGCGCAACATGGCGGTGCTGGTGGGGATGCTGGTCGGCGCCGGTCTGGCTT
ACGGCCTGGGCATGGGCAACTTTCACAGCGTCGAGGACGCGCCGTGGCTGACCGTGCCCTACCCGTTCTATTTCGGCTTG
CCGACTTTCAGCCTGATCCCCATCGCCACCATGGTCGTGGTGATGATCGTGCAGATGGTCGAGTCCATGGGGCTGTTCGT
GGCCATTGGAGACATTGTCGACAAACCGGTGGAAGACAAACAGGTCATCAATGGCCTGCGCGCCAACGGCCTGGCCAGCA
CCATCGCCGGGATGTTCGCCGCGTTTCCGTTCATTGCCTTCATGGAGAACGTCGGGCTGGTGATCCTGACCGGCGTGCGC
AGCCGTTGGGTGGTGGCGATCAGCGGACTGTTGATGTGCTCGATTGCGCTGGTGCCGAAGGCCGGGGCGATCATCGCTTC
GATGCCAACTGCTGCGCTGGGCGGTGCCGGTATCGCGATGTTCGGCGTGGTCGCGGCAGCGGGCATCCAGACCCTGGCCA
AGGTCGATTACGAGCGCAATCGCTACAACGTGCTGATCGTCGGTTTCACCATCGCCGCCGCCCTGGTGCCGGTGCTCGCC
CCGACCCTGTTCAAACAACTGCCCGAGTGGTCACAGCCGTTCCTGCACAGCAGCGTGGTCATCGCCTGCCTGGTGTCGGT
ACTGCTCAACGCGGCGCTCAACGGCGTCAGCATGCCAGAAACCACAGCCGGCAAATCCGCCTCGCACATCCTCTGA

Upstream 100 bases:

>100_bases
GCCAGCTGAAACCCGGCATCGGAGCCGGTGGATGGCGGTTCCGGGCACACAGAACGAATACCCCTCTGTACCGAATAACA
ACAGCTAGAGGTGATTCCCC

Downstream 100 bases:

>100_bases
CGGGAGCTGCCCATGACTCAACTTCAAAACATCCTGATCAAGCACCCGGTCGCGGTGATGACCGGCCTGCGCGGCCCCCG
TGCCCGGGCCGGTGCCGTGG

Product: xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MSSASSSSTVHPVDRVLPVRQMLTLGLQHMAVSYIGAIAVPLIVASALKMSHADTVVLISTTLFCSGIATLLQTVGFWRF
GVRLPILQGVAFSSVGPVIAIGSNPEVGFAGVCGAVIGAGIFTMLIAPFVGRLRRFFPPVVTGCIVTVIGLQLFPIAYEW
VGGGRNASNFGAPAFLAVAVVVLLTILLVNRYGSPLLRNMAVLVGMLVGAGLAYGLGMGNFHSVEDAPWLTVPYPFYFGL
PTFSLIPIATMVVVMIVQMVESMGLFVAIGDIVDKPVEDKQVINGLRANGLASTIAGMFAAFPFIAFMENVGLVILTGVR
SRWVVAISGLLMCSIALVPKAGAIIASMPTAALGGAGIAMFGVVAAAGIQTLAKVDYERNRYNVLIVGFTIAAALVPVLA
PTLFKQLPEWSQPFLHSSVVIACLVSVLLNAALNGVSMPETTAGKSASHIL

Sequences:

>Translated_451_residues
MSSASSSSTVHPVDRVLPVRQMLTLGLQHMAVSYIGAIAVPLIVASALKMSHADTVVLISTTLFCSGIATLLQTVGFWRF
GVRLPILQGVAFSSVGPVIAIGSNPEVGFAGVCGAVIGAGIFTMLIAPFVGRLRRFFPPVVTGCIVTVIGLQLFPIAYEW
VGGGRNASNFGAPAFLAVAVVVLLTILLVNRYGSPLLRNMAVLVGMLVGAGLAYGLGMGNFHSVEDAPWLTVPYPFYFGL
PTFSLIPIATMVVVMIVQMVESMGLFVAIGDIVDKPVEDKQVINGLRANGLASTIAGMFAAFPFIAFMENVGLVILTGVR
SRWVVAISGLLMCSIALVPKAGAIIASMPTAALGGAGIAMFGVVAAAGIQTLAKVDYERNRYNVLIVGFTIAAALVPVLA
PTLFKQLPEWSQPFLHSSVVIACLVSVLLNAALNGVSMPETTAGKSASHIL
>Mature_450_residues
SSASSSSTVHPVDRVLPVRQMLTLGLQHMAVSYIGAIAVPLIVASALKMSHADTVVLISTTLFCSGIATLLQTVGFWRFG
VRLPILQGVAFSSVGPVIAIGSNPEVGFAGVCGAVIGAGIFTMLIAPFVGRLRRFFPPVVTGCIVTVIGLQLFPIAYEWV
GGGRNASNFGAPAFLAVAVVVLLTILLVNRYGSPLLRNMAVLVGMLVGAGLAYGLGMGNFHSVEDAPWLTVPYPFYFGLP
TFSLIPIATMVVVMIVQMVESMGLFVAIGDIVDKPVEDKQVINGLRANGLASTIAGMFAAFPFIAFMENVGLVILTGVRS
RWVVAISGLLMCSIALVPKAGAIIASMPTAALGGAGIAMFGVVAAAGIQTLAKVDYERNRYNVLIVGFTIAAALVPVLAP
TLFKQLPEWSQPFLHSSVVIACLVSVLLNAALNGVSMPETTAGKSASHIL

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=466, Percent_Identity=27.0386266094421, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI40316845, Length=466, Percent_Identity=27.0386266094421, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI44680145, Length=444, Percent_Identity=26.8018018018018, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI44680143, Length=448, Percent_Identity=26.5625, Blast_Score=111, Evalue=2e-24,
Organism=Escherichia coli, GI87082181, Length=449, Percent_Identity=41.4253897550111, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI1790087, Length=444, Percent_Identity=30.4054054054054, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI87082178, Length=447, Percent_Identity=29.3064876957494, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI87081818, Length=411, Percent_Identity=29.4403892944039, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788843, Length=384, Percent_Identity=28.125, Blast_Score=115, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17558856, Length=478, Percent_Identity=25.3138075313808, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71993493, Length=470, Percent_Identity=23.4042553191489, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21356175, Length=424, Percent_Identity=27.122641509434, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47028; Mature: 46897

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSASSSSTVHPVDRVLPVRQMLTLGLQHMAVSYIGAIAVPLIVASALKMSHADTVVLIS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHH
TTLFCSGIATLLQTVGFWRFGVRLPILQGVAFSSVGPVIAIGSNPEVGFAGVCGAVIGAG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHCCCCEEEECCCCCCCHHHHHHHHHHHH
IFTMLIAPFVGRLRRFFPPVVTGCIVTVIGLQLFPIAYEWVGGGRNASNFGAPAFLAVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
VVLLTILLVNRYGSPLLRNMAVLVGMLVGAGLAYGLGMGNFHSVEDAPWLTVPYPFYFGL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHCC
PTFSLIPIATMVVVMIVQMVESMGLFVAIGDIVDKPVEDKQVINGLRANGLASTIAGMFA
CHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHH
AFPFIAFMENVGLVILTGVRSRWVVAISGLLMCSIALVPKAGAIIASMPTAALGGAGIAM
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHCCCHHHH
FGVVAAAGIQTLAKVDYERNRYNVLIVGFTIAAALVPVLAPTLFKQLPEWSQPFLHSSVV
HHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
IACLVSVLLNAALNGVSMPETTAGKSASHIL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]