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The map label for this gene is yjiA [H]

Identifier: 77459654

GI number: 77459654

Start: 3913238

End: 3914281

Strand: Direct

Name: yjiA [H]

Synonym: Pfl01_3432

Alternate gene names: 77459654

Gene position: 3913238-3914281 (Clockwise)

Preceding gene: 77459653

Following gene: 77459655

Centisome position: 60.78

GC content: 62.26

Gene sequence:

>1044_bases
ATGAACACGCCCTTCAACGCCCCGACCCCGAACACCAAAATCCCGGTCACCATCCTCACCGGGTTCCTCGGTGCCGGCAA
AACCACCCTGCTCAATTACATCCTCAAGGAGAACCACGGCCGCAAGATCGCGGTAATCGAAAACGAGTTCGGTGAAGTCG
GCATCGACGGCGATCTGGTGCTCAGCTCCGAGACCGAAGAGATCTACGAAATGGTCAACGGCTGCGTCTGCTGCACCGCC
GAAGTCCGCGAAGATCTGGTGCGCATCGTCCGCGAACTGGTGGCGCGTCCGGTACGGCTCGACCACATCCTGATCGAGAC
CAGCGGCCTCGCCGACCCGTACCCGGTGGCCCAGAGCTTTTTCATCAACGACCCGATTGCCGAGGAAGTCGAACTCGACG
CGATCGTGACCATGGTCGATGCCAAGCACATCGCCCAGCACCTGGAAGACCTGCAACTGGACGGCGTCGACAATCAGGCG
GTGGATCAGATCGTCTGCGCCGACCGCATCGTCATCAACAAGGTCGATCTGGTCAGCGCTGAAGAGGTGGAAACCCTGCG
CGGCAAAATCCGTGGATTGAACGCCACGGCGGATCTGGTGACCTCGACCCACGCACAAATCGACCTGTCGAAAATCCTCG
GCATCGGCGCCTTCGAATGCACGCAGAAGCTGATGGAGATCGGCGCGGATCAGCACGATCACCACGACCATGGCCACCAA
ACTGAAGAGCCCGACCACGAGCACGACCCAAGCGTTTCGTCCGTTGGCATCGCCGTGGACGGCGCCGTCAACCTGATGGC
GTTCCACCGCTGGATCAGCGAGTTGCGCAGTTCCCAGGCCGACAACCTGTACCGCATGAAAGGCGTGCTGGCGGTGGCCA
ATGAAGACCAGCGCTACGTGCTGCAAGGCGTGCACAGCCTGGTGGAGTTCCGCGCCTCGACCGCGTGGGGCAGCGAGCCG
CGCTCGAGCAAGATCGTGTTCATCGGCCGCGACCTGGATCGGGCGGCGCTGAACCAGGGCTTCGCCGCCTGCCTGGCCAG
CTGA

Upstream 100 bases:

>100_bases
CCGGCGTCGCGCTGCGCTGGGGTGAAACCCCGGCCCCGAGCCAAATCCAGCCTCACTCCCCTTCATCGTGCACCGGTCTA
TCAATACCAAGGAGCCTCAC

Downstream 100 bases:

>100_bases
AACCCGGCATCGGAGCCGGTGGATGGCGGTTCCGGGCACACAGAACGAATACCCCTCTGTACCGAATAACAACAGCTAGA
GGTGATTCCCCATGTCGTCA

Product: cobalamin synthesis protein/P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MNTPFNAPTPNTKIPVTILTGFLGAGKTTLLNYILKENHGRKIAVIENEFGEVGIDGDLVLSSETEEIYEMVNGCVCCTA
EVREDLVRIVRELVARPVRLDHILIETSGLADPYPVAQSFFINDPIAEEVELDAIVTMVDAKHIAQHLEDLQLDGVDNQA
VDQIVCADRIVINKVDLVSAEEVETLRGKIRGLNATADLVTSTHAQIDLSKILGIGAFECTQKLMEIGADQHDHHDHGHQ
TEEPDHEHDPSVSSVGIAVDGAVNLMAFHRWISELRSSQADNLYRMKGVLAVANEDQRYVLQGVHSLVEFRASTAWGSEP
RSSKIVFIGRDLDRAALNQGFAACLAS

Sequences:

>Translated_347_residues
MNTPFNAPTPNTKIPVTILTGFLGAGKTTLLNYILKENHGRKIAVIENEFGEVGIDGDLVLSSETEEIYEMVNGCVCCTA
EVREDLVRIVRELVARPVRLDHILIETSGLADPYPVAQSFFINDPIAEEVELDAIVTMVDAKHIAQHLEDLQLDGVDNQA
VDQIVCADRIVINKVDLVSAEEVETLRGKIRGLNATADLVTSTHAQIDLSKILGIGAFECTQKLMEIGADQHDHHDHGHQ
TEEPDHEHDPSVSSVGIAVDGAVNLMAFHRWISELRSSQADNLYRMKGVLAVANEDQRYVLQGVHSLVEFRASTAWGSEP
RSSKIVFIGRDLDRAALNQGFAACLAS
>Mature_347_residues
MNTPFNAPTPNTKIPVTILTGFLGAGKTTLLNYILKENHGRKIAVIENEFGEVGIDGDLVLSSETEEIYEMVNGCVCCTA
EVREDLVRIVRELVARPVRLDHILIETSGLADPYPVAQSFFINDPIAEEVELDAIVTMVDAKHIAQHLEDLQLDGVDNQA
VDQIVCADRIVINKVDLVSAEEVETLRGKIRGLNATADLVTSTHAQIDLSKILGIGAFECTQKLMEIGADQHDHHDHGHQ
TEEPDHEHDPSVSSVGIAVDGAVNLMAFHRWISELRSSQADNLYRMKGVLAVANEDQRYVLQGVHSLVEFRASTAWGSEP
RSSKIVFIGRDLDRAALNQGFAACLAS

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=348, Percent_Identity=35.632183908046, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI126722884, Length=348, Percent_Identity=35.632183908046, Blast_Score=215, Evalue=4e-56,
Organism=Homo sapiens, GI148727351, Length=348, Percent_Identity=35.632183908046, Blast_Score=211, Evalue=8e-55,
Organism=Homo sapiens, GI146231952, Length=348, Percent_Identity=35.3448275862069, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI223941779, Length=348, Percent_Identity=33.6206896551724, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI223941776, Length=337, Percent_Identity=34.1246290801187, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI119120938, Length=344, Percent_Identity=32.5581395348837, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI310124603, Length=238, Percent_Identity=27.3109243697479, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI310124599, Length=203, Percent_Identity=29.064039408867, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI169184311, Length=180, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI87082430, Length=332, Percent_Identity=34.6385542168675, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1788499, Length=290, Percent_Identity=27.2413793103448, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324356, Length=244, Percent_Identity=33.1967213114754, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 38018; Mature: 38018

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPFNAPTPNTKIPVTILTGFLGAGKTTLLNYILKENHGRKIAVIENEFGEVGIDGDLV
CCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEE
LSSETEEIYEMVNGCVCCTAEVREDLVRIVRELVARPVRLDHILIETSGLADPYPVAQSF
ECCCHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHH
FINDPIAEEVELDAIVTMVDAKHIAQHLEDLQLDGVDNQAVDQIVCADRIVINKVDLVSA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHEEEEECCCCH
EEVETLRGKIRGLNATADLVTSTHAQIDLSKILGIGAFECTQKLMEIGADQHDHHDHGHQ
HHHHHHHHHHCCCCCHHHHHHHHHHHEEHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCC
TEEPDHEHDPSVSSVGIAVDGAVNLMAFHRWISELRSSQADNLYRMKGVLAVANEDQRYV
CCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHCEEEECCCCHHHH
LQGVHSLVEFRASTAWGSEPRSSKIVFIGRDLDRAALNQGFAACLAS
HHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTPFNAPTPNTKIPVTILTGFLGAGKTTLLNYILKENHGRKIAVIENEFGEVGIDGDLV
CCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEE
LSSETEEIYEMVNGCVCCTAEVREDLVRIVRELVARPVRLDHILIETSGLADPYPVAQSF
ECCCHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHH
FINDPIAEEVELDAIVTMVDAKHIAQHLEDLQLDGVDNQAVDQIVCADRIVINKVDLVSA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHEEEEECCCCH
EEVETLRGKIRGLNATADLVTSTHAQIDLSKILGIGAFECTQKLMEIGADQHDHHDHGHQ
HHHHHHHHHHCCCCCHHHHHHHHHHHEEHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCC
TEEPDHEHDPSVSSVGIAVDGAVNLMAFHRWISELRSSQADNLYRMKGVLAVANEDQRYV
CCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHCEEEECCCCHHHH
LQGVHSLVEFRASTAWGSEPRSSKIVFIGRDLDRAALNQGFAACLAS
HHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]