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The map label for this gene is nahR [H]

Identifier: 77459604

GI number: 77459604

Start: 3856616

End: 3857503

Strand: Direct

Name: nahR [H]

Synonym: Pfl01_3382

Alternate gene names: 77459604

Gene position: 3856616-3857503 (Clockwise)

Preceding gene: 77459602

Following gene: 77459606

Centisome position: 59.9

GC content: 66.78

Gene sequence:

>888_bases
ATGAATGCACCGGATCTGAACCTGTTGATCACCCTCGACGTGCTCCTGAGCGAAGGCAGCGTCGCCCGCGCCGCCGAACG
CCTGCGTCTGAGCCCTTCCGCCATGAGCCGCGCATTGGCCCGGCTGCGGGAAACCACCGGCGATCCGCTGCTGGTGCGTG
CCGGTCGTGGGCTGGTGCCGACCCCGCGTGCGCTGGAGCTGCGCGACCGGGTCAGTTATCTGGTGCAGGAAGCCGAAGCG
GTTTTGCGCCCGGCAGAAGTGCTCGATCCCGGCCAGTTGCGGCGCACCTTCACCCTGCGCAACACCGACGGGTTCGTCGA
AACCTTCGCCGCCGCCCTGCTCGCCCGCATCGCCGAAGAGGCCCCCGGCGTGCGCCTGCGCTTTGTGCAAAAGGCTGACA
AGGACAGCACGCTGCTGCGCGTAGGCCGGGTGGATCTGGAAACCGGCGTGGTCGACGACAGCACCGACCCGACGCTGCAC
AGTCGCATCCTGTTCCGCGATCAGTGGATCGGAGTGGTGCGTGAAGGACATCCGCTGAGCAGCGGCAAGGTCAGCGCCAA
ACGCTTTGCTGCAGGCCAGCACATTCTGGTGTCACGGCGCGGGCGCAGCAGCGGACCGGTGGACGAGGCATTGCTCGCCT
TCGGGCTGACGCGGGATATCGTCACCTCGTTCGGCGGATTTTCGGCGGCGCTGACGCTGGTCCGTGAATCGGACCTGATC
GCCACCGTTCCGGAACGTCACACCAGCAAACTGCGCACGGGCCTGCACAGCTTCGCCCTGCCCTTGCGCATGCCGGATAT
CAGCGTGTCGATGCTTTGGCACCCGCGCATGGACGCCGACCCGGCGCATCGCTGGTTGCGCAATTGCGTGCGCGAAGTCT
GCGCCTAA

Upstream 100 bases:

>100_bases
GGGCTCACAGGGCAAAGGTCATGCGACATAGCCTGAGCCTCGACAATACAAGGCGCAAGACGCATGCTTTGCACTTGATA
CCTGCATGGAACGCCATGTC

Downstream 100 bases:

>100_bases
CGCGCATCCCCGCCCGCGGGTTTGTAGAACAGGAATTTCCTGGTCTCGGCGGTTTTTCTGTATTCCTTGGCCCAGCTCGG
ATGTACGTTGCGGTCGTGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNAPDLNLLITLDVLLSEGSVARAAERLRLSPSAMSRALARLRETTGDPLLVRAGRGLVPTPRALELRDRVSYLVQEAEA
VLRPAEVLDPGQLRRTFTLRNTDGFVETFAAALLARIAEEAPGVRLRFVQKADKDSTLLRVGRVDLETGVVDDSTDPTLH
SRILFRDQWIGVVREGHPLSSGKVSAKRFAAGQHILVSRRGRSSGPVDEALLAFGLTRDIVTSFGGFSAALTLVRESDLI
ATVPERHTSKLRTGLHSFALPLRMPDISVSMLWHPRMDADPAHRWLRNCVREVCA

Sequences:

>Translated_295_residues
MNAPDLNLLITLDVLLSEGSVARAAERLRLSPSAMSRALARLRETTGDPLLVRAGRGLVPTPRALELRDRVSYLVQEAEA
VLRPAEVLDPGQLRRTFTLRNTDGFVETFAAALLARIAEEAPGVRLRFVQKADKDSTLLRVGRVDLETGVVDDSTDPTLH
SRILFRDQWIGVVREGHPLSSGKVSAKRFAAGQHILVSRRGRSSGPVDEALLAFGLTRDIVTSFGGFSAALTLVRESDLI
ATVPERHTSKLRTGLHSFALPLRMPDISVSMLWHPRMDADPAHRWLRNCVREVCA
>Mature_295_residues
MNAPDLNLLITLDVLLSEGSVARAAERLRLSPSAMSRALARLRETTGDPLLVRAGRGLVPTPRALELRDRVSYLVQEAEA
VLRPAEVLDPGQLRRTFTLRNTDGFVETFAAALLARIAEEAPGVRLRFVQKADKDSTLLRVGRVDLETGVVDDSTDPTLH
SRILFRDQWIGVVREGHPLSSGKVSAKRFAAGQHILVSRRGRSSGPVDEALLAFGLTRDIVTSFGGFSAALTLVRESDLI
ATVPERHTSKLRTGLHSFALPLRMPDISVSMLWHPRMDADPAHRWLRNCVREVCA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=299, Percent_Identity=26.4214046822742, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790147, Length=303, Percent_Identity=25.4125412541254, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87081766, Length=245, Percent_Identity=27.3469387755102, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786820, Length=95, Percent_Identity=32.6315789473684, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32460; Mature: 32460

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPDLNLLITLDVLLSEGSVARAAERLRLSPSAMSRALARLRETTGDPLLVRAGRGLVP
CCCCCCEEEEEEEHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCC
TPRALELRDRVSYLVQEAEAVLRPAEVLDPGQLRRTFTLRNTDGFVETFAAALLARIAEE
CCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHEEEEEECCCCHHHHHHHHHHHHHHHHH
APGVRLRFVQKADKDSTLLRVGRVDLETGVVDDSTDPTLHSRILFRDQWIGVVREGHPLS
CCCCEEEEEHHCCCCCCEEEECCEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
SGKVSAKRFAAGQHILVSRRGRSSGPVDEALLAFGLTRDIVTSFGGFSAALTLVRESDLI
CCCCHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCE
ATVPERHTSKLRTGLHSFALPLRMPDISVSMLWHPRMDADPAHRWLRNCVREVCA
EECCHHHHHHHHHHHHHHHCCEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAPDLNLLITLDVLLSEGSVARAAERLRLSPSAMSRALARLRETTGDPLLVRAGRGLVP
CCCCCCEEEEEEEHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCC
TPRALELRDRVSYLVQEAEAVLRPAEVLDPGQLRRTFTLRNTDGFVETFAAALLARIAEE
CCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHEEEEEECCCCHHHHHHHHHHHHHHHHH
APGVRLRFVQKADKDSTLLRVGRVDLETGVVDDSTDPTLHSRILFRDQWIGVVREGHPLS
CCCCEEEEEHHCCCCCCEEEECCEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
SGKVSAKRFAAGQHILVSRRGRSSGPVDEALLAFGLTRDIVTSFGGFSAALTLVRESDLI
CCCCHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCE
ATVPERHTSKLRTGLHSFALPLRMPDISVSMLWHPRMDADPAHRWLRNCVREVCA
EECCHHHHHHHHHHHHHHHCCEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]