Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 77459525

GI number: 77459525

Start: 3784858

End: 3785595

Strand: Direct

Name: ompR [H]

Synonym: Pfl01_3303

Alternate gene names: 77459525

Gene position: 3784858-3785595 (Clockwise)

Preceding gene: 77459524

Following gene: 77459526

Centisome position: 58.79

GC content: 63.96

Gene sequence:

>738_bases
ATGGATCACATCAACCACATCCTGATCGTCGACGATGACCGCGAGATCCGCGAACTGGTCGGCAATTACCTGACCAAGAA
CGGCCTGCGCAGCACCGTGGTCGCCGATGGCCGGCAGATGCGCAGTTTTCTGGAAGCCAACACGGTCGACCTGATCGTGC
TCGACATCATGCTCCCCGGCGATGACGGGCTGGTGCTGTGCCGCGAATTGCGCGCCGGCAAACACAAGGCGATCCCGATC
CTGATGCTCACCGCCCGCGACGACCAGACCGACCGCATCCTCGGCCTGGAAATGGGCGCCGACGACTACCTGACCAAACC
CTTCGCCGCCCGCGAACTGCTGGCGCGGATCAACGCCGTGCTGCGCCGTACACGAATGCTGCCGCCCAATCTGCTGATCA
GCGAAACCGGGCGCCTGCTCGCGTTCGGCCGCTGGCGCCTGGACACCACCGCCCGCCACCTGCTCGATGAAGACGACACC
ATGGTTGCCCTCAGCGGCGCCGAGTATCGCCTGCTCCGGGTGTTTCTCGACCATCCGCAACGGGTGCTCAGCCGCGACCA
GTTGCTCAATCTGACTCAGGGTCGCGACGCCGACCTGTTCGACCGCTCCATCGATTTGCTGGTCAGTCGCCTGCGCCAGC
GTCTGCTGGACGACTCCCGCGAGCCGACTTACATCAAGACCGTGCGCAACGAGGGTTATGTGTTCTCCTTCGCCGTGGAG
ATGCTCGCCGAATCCTGA

Upstream 100 bases:

>100_bases
GGCGCGGCGTATGTGCCGTGCTACCGCGTGGTGTCCTGACCCGAAGTGACAAGTGCCCGGAGCGCAACGCTTCGGGCACT
CCCTATAAAAAGAGCGAACC

Downstream 100 bases:

>100_bases
CGGATTTGTATCGCTCTGTATAAATTCGCCGCGCAGATACGTAACCCGTGTTTTCGCGCCGCATCACCACATATCAGCGA
TACACCCTCGCGTTTGAATG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MDHINHILIVDDDREIRELVGNYLTKNGLRSTVVADGRQMRSFLEANTVDLIVLDIMLPGDDGLVLCRELRAGKHKAIPI
LMLTARDDQTDRILGLEMGADDYLTKPFAARELLARINAVLRRTRMLPPNLLISETGRLLAFGRWRLDTTARHLLDEDDT
MVALSGAEYRLLRVFLDHPQRVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDSREPTYIKTVRNEGYVFSFAVE
MLAES

Sequences:

>Translated_245_residues
MDHINHILIVDDDREIRELVGNYLTKNGLRSTVVADGRQMRSFLEANTVDLIVLDIMLPGDDGLVLCRELRAGKHKAIPI
LMLTARDDQTDRILGLEMGADDYLTKPFAARELLARINAVLRRTRMLPPNLLISETGRLLAFGRWRLDTTARHLLDEDDT
MVALSGAEYRLLRVFLDHPQRVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDSREPTYIKTVRNEGYVFSFAVE
MLAES
>Mature_245_residues
MDHINHILIVDDDREIRELVGNYLTKNGLRSTVVADGRQMRSFLEANTVDLIVLDIMLPGDDGLVLCRELRAGKHKAIPI
LMLTARDDQTDRILGLEMGADDYLTKPFAARELLARINAVLRRTRMLPPNLLISETGRLLAFGRWRLDTTARHLLDEDDT
MVALSGAEYRLLRVFLDHPQRVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDSREPTYIKTVRNEGYVFSFAVE
MLAES

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=45.531914893617, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=38.5281385281385, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1790863, Length=238, Percent_Identity=36.1344537815126, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788394, Length=239, Percent_Identity=36.8200836820084, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI145693140, Length=245, Percent_Identity=37.1428571428571, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI1787229, Length=236, Percent_Identity=36.4406779661017, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=34.3612334801762, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI2367329, Length=241, Percent_Identity=36.5145228215768, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786911, Length=235, Percent_Identity=35.3191489361702, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=34.061135371179, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=36.2445414847162, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=30.4721030042918, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=33.9130434782609, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=34.7826086956522, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1790299, Length=109, Percent_Identity=33.9449541284404, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=32.520325203252, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=30.0884955752212, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28039; Mature: 28039

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHINHILIVDDDREIRELVGNYLTKNGLRSTVVADGRQMRSFLEANTVDLIVLDIMLPG
CCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHCCCEEEEEEEEEECC
DDGLVLCRELRAGKHKAIPILMLTARDDQTDRILGLEMGADDYLTKPFAARELLARINAV
CCCHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCHHHCCCHHHHHHHHHHHHH
LRRTRMLPPNLLISETGRLLAFGRWRLDTTARHLLDEDDTMVALSGAEYRLLRVFLDHPQ
HHHHHCCCCCCEECCCCCEEEEEEEEHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCHH
RVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDSREPTYIKTVRNEGYVFSFAVE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHHHH
MLAES
HHHCC
>Mature Secondary Structure
MDHINHILIVDDDREIRELVGNYLTKNGLRSTVVADGRQMRSFLEANTVDLIVLDIMLPG
CCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHCCCEEEEEEEEEECC
DDGLVLCRELRAGKHKAIPILMLTARDDQTDRILGLEMGADDYLTKPFAARELLARINAV
CCCHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCHHHCCCHHHHHHHHHHHHH
LRRTRMLPPNLLISETGRLLAFGRWRLDTTARHLLDEDDTMVALSGAEYRLLRVFLDHPQ
HHHHHCCCCCCEECCCCCEEEEEEEEHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCHH
RVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDSREPTYIKTVRNEGYVFSFAVE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHHHH
MLAES
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]