Click here to switch to the map view.

The map label for this gene is ttuB [H]

Identifier: 77459506

GI number: 77459506

Start: 3769769

End: 3771136

Strand: Reverse

Name: ttuB [H]

Synonym: Pfl01_3284

Alternate gene names: 77459506

Gene position: 3771136-3769769 (Counterclockwise)

Preceding gene: 77459508

Following gene: 77459505

Centisome position: 58.57

GC content: 61.26

Gene sequence:

>1368_bases
TTGAAAAACCTCCAGAGTTCGCCGGACATCACGGTACTCGCCCGCGCTGCCGCCAAGGTCAAGCGCCATGTGCTGCCGTT
GTTCGTGGTGATGTTCATCGTCAACTACATCGACCGGGTCAACATCGGTTTCGTGCGCAGTCATCTGGAAACCGATCTGG
GTATCGGTGCTGCCGCCTATGGCCTTGGCGCCGGTCTGTTTTTCATCGGTTACGCCTTGTTTGAAGTGCCGTCCAACATG
CTTCTGCAACGCTACGGCGCCCGCGCCTGGCTGACGCGGATCATGTTCACCTGGGGCGCAGCGGCGATGGCCATGGCGTT
CGTCAAAGGCGAAACCAGTTTCTACGTGCTGCGCTTCATCCTGGGCGCTGCCGAAGCCGGCTTCTTCCCGGGGATCATTT
ATTACTTCACCCAATGGCTGCCGGCTTCTGAACGCGGCAAGACCATGGCGGTATTTCTCAGCGGGTCGGCGATTGCTTCG
GTGATATCCGGTCCGGTGTCCGGCGCGTTGTTGCATATCAGCGGCCTGGGCATGCACGGCTGGCAGTGGATGTTCCTGAT
CGAAGGCGCTGCGTCGGTGGTGCTCTGCGGGTTTGTCTGGTTCTGGCTGCAATCCCATCCGCGCCAGGCCAAGTGGCTGA
CCGAAGAGGAGCGTGAAGCGCTGGTGACGGCAATCGCCGAGGAACAACGTGCCCGCGAAGCGACCCGCGTCGCCAAACCA
TCGATGTTCAAACTGTTGGCGGATCGGCAGATCGCATTGTTCTGCTTCATCTACTTCTCCATCGCCCTGACCATCTACGG
CGCCACCTTCTGGCTGCCGAGCATGATCAAGAAAATGGGCAACCTCGGCGACTTCCAGGTCGGGCTGCTCAACTCGGTGC
CGTGGATCATTTCCATCGTCGCGATGTACGGCTTTGCGGCGCTGGCGGGCAAGTGGAAATTCCAGCAGGCCTGGGTCGCA
CTGACCCTGGTGATCGCCGCATTCGGCATGTTCATGTCCACCACCGGCGGGCCGATTTTCGCCTTCGTCGCGATCTGTTT
TGCGGCCATCGGTTTCAAGGCGGCTTCGGCACTGTTCTGGCCGATTCCGCAGAGCTATCTGGATGCGCGCATCGCGGCGG
CAGTCATTGCTCTGATCAACTCCATCGGCAACCTCGGCGGCTTCGTTGCGCCGACCGCGTTCGGTTTTCTGGAACAGACC
ACCGGCTCTATCGAGGGCGGTCTGTATGGCCTGGCCGCGACTTCGCTGATAGCGGCGGTGGTGATCTTCTTCGCCCGCAT
GGCGCCCGGCGCCAAAGGCAACACCCCGGCAAAGCCTGAACCCGAAACCGCCGTTGCGCCGACGGCCAACCCGCTGGCGA
GCCACTGA

Upstream 100 bases:

>100_bases
CGAATGCCAGGTTAGATTAGACGGGATCAATTGCCCCGTCCATGATCGCTCTACGCCTGAACAGGCCTTCCCTACAAAAA
CAAAGATCGGGAGTCGCCCC

Downstream 100 bases:

>100_bases
TTCCGACTCAACAGGAGCGTCATTTTGAAAATCACTCGCGTAACCGTCACTCCGATTGCCTTCCGTGATCCGCCGCTGCT
CAACGCCAGTGGCATCCACG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MKNLQSSPDITVLARAAAKVKRHVLPLFVVMFIVNYIDRVNIGFVRSHLETDLGIGAAAYGLGAGLFFIGYALFEVPSNM
LLQRYGARAWLTRIMFTWGAAAMAMAFVKGETSFYVLRFILGAAEAGFFPGIIYYFTQWLPASERGKTMAVFLSGSAIAS
VISGPVSGALLHISGLGMHGWQWMFLIEGAASVVLCGFVWFWLQSHPRQAKWLTEEEREALVTAIAEEQRAREATRVAKP
SMFKLLADRQIALFCFIYFSIALTIYGATFWLPSMIKKMGNLGDFQVGLLNSVPWIISIVAMYGFAALAGKWKFQQAWVA
LTLVIAAFGMFMSTTGGPIFAFVAICFAAIGFKAASALFWPIPQSYLDARIAAAVIALINSIGNLGGFVAPTAFGFLEQT
TGSIEGGLYGLAATSLIAAVVIFFARMAPGAKGNTPAKPEPETAVAPTANPLASH

Sequences:

>Translated_455_residues
MKNLQSSPDITVLARAAAKVKRHVLPLFVVMFIVNYIDRVNIGFVRSHLETDLGIGAAAYGLGAGLFFIGYALFEVPSNM
LLQRYGARAWLTRIMFTWGAAAMAMAFVKGETSFYVLRFILGAAEAGFFPGIIYYFTQWLPASERGKTMAVFLSGSAIAS
VISGPVSGALLHISGLGMHGWQWMFLIEGAASVVLCGFVWFWLQSHPRQAKWLTEEEREALVTAIAEEQRAREATRVAKP
SMFKLLADRQIALFCFIYFSIALTIYGATFWLPSMIKKMGNLGDFQVGLLNSVPWIISIVAMYGFAALAGKWKFQQAWVA
LTLVIAAFGMFMSTTGGPIFAFVAICFAAIGFKAASALFWPIPQSYLDARIAAAVIALINSIGNLGGFVAPTAFGFLEQT
TGSIEGGLYGLAATSLIAAVVIFFARMAPGAKGNTPAKPEPETAVAPTANPLASH
>Mature_455_residues
MKNLQSSPDITVLARAAAKVKRHVLPLFVVMFIVNYIDRVNIGFVRSHLETDLGIGAAAYGLGAGLFFIGYALFEVPSNM
LLQRYGARAWLTRIMFTWGAAAMAMAFVKGETSFYVLRFILGAAEAGFFPGIIYYFTQWLPASERGKTMAVFLSGSAIAS
VISGPVSGALLHISGLGMHGWQWMFLIEGAASVVLCGFVWFWLQSHPRQAKWLTEEEREALVTAIAEEQRAREATRVAKP
SMFKLLADRQIALFCFIYFSIALTIYGATFWLPSMIKKMGNLGDFQVGLLNSVPWIISIVAMYGFAALAGKWKFQQAWVA
LTLVIAAFGMFMSTTGGPIFAFVAICFAAIGFKAASALFWPIPQSYLDARIAAAVIALINSIGNLGGFVAPTAFGFLEQT
TGSIEGGLYGLAATSLIAAVVIFFARMAPGAKGNTPAKPEPETAVAPTANPLASH

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=398, Percent_Identity=22.3618090452261, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI9966811, Length=391, Percent_Identity=24.2966751918159, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI154350196, Length=382, Percent_Identity=21.2041884816754, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87082071, Length=420, Percent_Identity=35, Blast_Score=265, Evalue=4e-72,
Organism=Escherichia coli, GI1789152, Length=443, Percent_Identity=26.6365688487585, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082320, Length=437, Percent_Identity=24.2562929061785, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789515, Length=445, Percent_Identity=23.5955056179775, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI2367379, Length=422, Percent_Identity=24.1706161137441, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI2367193, Length=236, Percent_Identity=24.5762711864407, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321698, Length=275, Percent_Identity=23.6363636363636, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319876, Length=190, Percent_Identity=26.8421052631579, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322612, Length=241, Percent_Identity=21.5767634854772, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322025, Length=253, Percent_Identity=22.5296442687747, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323032, Length=241, Percent_Identity=22.8215767634855, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322973, Length=249, Percent_Identity=22.4899598393574, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324410, Length=146, Percent_Identity=26.7123287671233, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24639764, Length=368, Percent_Identity=25, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24583789, Length=401, Percent_Identity=23.6907730673317, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28573708, Length=362, Percent_Identity=23.4806629834254, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573707, Length=362, Percent_Identity=23.4806629834254, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20130167, Length=362, Percent_Identity=21.5469613259669, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550460, Length=195, Percent_Identity=29.7435897435897, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24655255, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641682, Length=385, Percent_Identity=24.1558441558442, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24658696, Length=410, Percent_Identity=21.9512195121951, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20130135, Length=364, Percent_Identity=20.0549450549451, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24655271, Length=416, Percent_Identity=19.7115384615385, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49131; Mature: 49131

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLQSSPDITVLARAAAKVKRHVLPLFVVMFIVNYIDRVNIGFVRSHLETDLGIGAAAY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHH
GLGAGLFFIGYALFEVPSNMLLQRYGARAWLTRIMFTWGAAAMAMAFVKGETSFYVLRFI
HHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LGAAEAGFFPGIIYYFTQWLPASERGKTMAVFLSGSAIASVISGPVSGALLHISGLGMHG
HHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCC
WQWMFLIEGAASVVLCGFVWFWLQSHPRQAKWLTEEEREALVTAIAEEQRAREATRVAKP
EEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
SMFKLLADRQIALFCFIYFSIALTIYGATFWLPSMIKKMGNLGDFQVGLLNSVPWIISIV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCHHHHHHHH
AMYGFAALAGKWKFQQAWVALTLVIAAFGMFMSTTGGPIFAFVAICFAAIGFKAASALFW
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
PIPQSYLDARIAAAVIALINSIGNLGGFVAPTAFGFLEQTTGSIEGGLYGLAATSLIAAV
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VIFFARMAPGAKGNTPAKPEPETAVAPTANPLASH
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNLQSSPDITVLARAAAKVKRHVLPLFVVMFIVNYIDRVNIGFVRSHLETDLGIGAAAY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHH
GLGAGLFFIGYALFEVPSNMLLQRYGARAWLTRIMFTWGAAAMAMAFVKGETSFYVLRFI
HHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LGAAEAGFFPGIIYYFTQWLPASERGKTMAVFLSGSAIASVISGPVSGALLHISGLGMHG
HHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCC
WQWMFLIEGAASVVLCGFVWFWLQSHPRQAKWLTEEEREALVTAIAEEQRAREATRVAKP
EEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
SMFKLLADRQIALFCFIYFSIALTIYGATFWLPSMIKKMGNLGDFQVGLLNSVPWIISIV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCHHHHHHHH
AMYGFAALAGKWKFQQAWVALTLVIAAFGMFMSTTGGPIFAFVAICFAAIGFKAASALFW
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
PIPQSYLDARIAAAVIALINSIGNLGGFVAPTAFGFLEQTTGSIEGGLYGLAATSLIAAV
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VIFFARMAPGAKGNTPAKPEPETAVAPTANPLASH
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]