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The map label for this gene is yxlA [H]

Identifier: 77459492

GI number: 77459492

Start: 3752077

End: 3753492

Strand: Direct

Name: yxlA [H]

Synonym: Pfl01_3270

Alternate gene names: 77459492

Gene position: 3752077-3753492 (Clockwise)

Preceding gene: 77459491

Following gene: 77459494

Centisome position: 58.28

GC content: 62.5

Gene sequence:

>1416_bases
ATGGCCACCTCTGCAACAACGTCCGCACCGCTCATTGAGAAACACACGATCGGCTATGTGCCGCCCGAAGATCGCCACGG
AAAGGTTCGGGATCTGTTCACCCTCTGGTTCGGCGGCAATATCGCGCCGTTGCCCATCGTCACCGGCGCCCTCGGCGTGC
AGCTGTTTCACCTGAATCTGGTGTGGGGCATCGTCGCCATTCTGGTTGGCCATCTGGTCGGCGGTGTGCTGATGGCGCTG
CACTCGGCGCAGGGCCCGCAGATGGGCATTCCGCAGATGATCCAGAGCCGCGCACAATTCGGCTCCCTCGGCGCACTGCT
GGTGGTGTTGATCGCCGGCGTCATGTACATCGGCTTCTTCGCCTCCAACATCGTGCTCGCCGGCAAGTCCCTGCATGGAT
TGGTCGACAGCGTTCCGGTGCCGGTCGGCATCGTCATCGGCGCGCTGGGTTCGGGGATCATCGGGATCATCGGGTACCGC
TTCATCCACGTGCTCAACCGCATCGGCACCTGGGTCTTGGGGATCGGCATCGTGGTCGGCTTCGGCTACATCCTCACCCA
CATCCAGACCGATGATTTCCTCACACGCGGCAGCTTCAACCTCTCGGGCTGGCTGGCAACTGTGTCGCTGGCAGCGCTGT
GGCAGATCGCGTTTGCGCCGTACGTCTCGGACTACTCGCGTTACCTGCCGGCGAATGTGCCGGTGGCAGCGACCTTCTGG
ACAACCTATCTGGGATCGGCGCTGGGCTCGAGCCTGTCGTTCGTATTCGGCGCCGTCGCCGTGCTGGCAACCCCGGTGGG
TATGGACACCATGGACGCGGTGAAACTCGCCACCGGCGCCATCGGCCCGCTGATGCTGGTGCTGTTTCTGCTCAGCGTCA
TCAGCCACAACGCCCTCAACCTGTACGGCGCGGTGCTGTCGCTGATCACCCTGGTGCAGACCTTTGCCTACCGCTGGATT
CCAACCGCCAAGAGCCGCGCGGTGATTTCGATCATCGTCCTGCTGGCCTGCTGTTTCGCTGCGGTCGGCGCCTCGGCAGA
CTTCATCGGCCACTTCGTCGACATGGTGCTGGTGTTGTTGGTCGTACTGGTGCCGTGGACCGCGATCAACCTGATCGACT
TCTACGCCATCCACAAAGGCCAGTACGACATCGGCTCGATCTTCCAGGTCGACGGCGGCATCTACGGCCGTTACAACCCG
CAGGCCTTGCTGGCTTACGCGATCGGTATCGCGGTGCAGATTCCGTTCATGAACACGCCGCTGTACGTCGGGCCGGTGTC
GGCGCACATCAACGGCGCGGACCTGTCGTGGCTGGTTGGCTTGCTGGTGACCTCGCCGCTGTATTTCTGGCTGGCGACTC
GTGACAGTGCTTATCGTCGGCGGCTGACTTCCGGAAAACTGGCGAACAATCTGTAA

Upstream 100 bases:

>100_bases
CCCTTTCCTTGCCCATGATCAACCCCAACAAGAAATGCGCCGTCCGTGCCGGCGCTCACTGAAGTACGTCCACGTACTCG
TCCTTGCCTTGGAGTTCGTC

Downstream 100 bases:

>100_bases
GTCATCCGTTTTGCGCTGACACGCGAAGGCCCTCGCAAATGAGGGCCTTTTTTTGTTTTGGATGGAGCCGTCTATTTAGC
TTTGAACGCCTCACGCCGCG

Product: cytosine/purines, uracil, thiamine, allantoin permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MATSATTSAPLIEKHTIGYVPPEDRHGKVRDLFTLWFGGNIAPLPIVTGALGVQLFHLNLVWGIVAILVGHLVGGVLMAL
HSAQGPQMGIPQMIQSRAQFGSLGALLVVLIAGVMYIGFFASNIVLAGKSLHGLVDSVPVPVGIVIGALGSGIIGIIGYR
FIHVLNRIGTWVLGIGIVVGFGYILTHIQTDDFLTRGSFNLSGWLATVSLAALWQIAFAPYVSDYSRYLPANVPVAATFW
TTYLGSALGSSLSFVFGAVAVLATPVGMDTMDAVKLATGAIGPLMLVLFLLSVISHNALNLYGAVLSLITLVQTFAYRWI
PTAKSRAVISIIVLLACCFAAVGASADFIGHFVDMVLVLLVVLVPWTAINLIDFYAIHKGQYDIGSIFQVDGGIYGRYNP
QALLAYAIGIAVQIPFMNTPLYVGPVSAHINGADLSWLVGLLVTSPLYFWLATRDSAYRRRLTSGKLANNL

Sequences:

>Translated_471_residues
MATSATTSAPLIEKHTIGYVPPEDRHGKVRDLFTLWFGGNIAPLPIVTGALGVQLFHLNLVWGIVAILVGHLVGGVLMAL
HSAQGPQMGIPQMIQSRAQFGSLGALLVVLIAGVMYIGFFASNIVLAGKSLHGLVDSVPVPVGIVIGALGSGIIGIIGYR
FIHVLNRIGTWVLGIGIVVGFGYILTHIQTDDFLTRGSFNLSGWLATVSLAALWQIAFAPYVSDYSRYLPANVPVAATFW
TTYLGSALGSSLSFVFGAVAVLATPVGMDTMDAVKLATGAIGPLMLVLFLLSVISHNALNLYGAVLSLITLVQTFAYRWI
PTAKSRAVISIIVLLACCFAAVGASADFIGHFVDMVLVLLVVLVPWTAINLIDFYAIHKGQYDIGSIFQVDGGIYGRYNP
QALLAYAIGIAVQIPFMNTPLYVGPVSAHINGADLSWLVGLLVTSPLYFWLATRDSAYRRRLTSGKLANNL
>Mature_470_residues
ATSATTSAPLIEKHTIGYVPPEDRHGKVRDLFTLWFGGNIAPLPIVTGALGVQLFHLNLVWGIVAILVGHLVGGVLMALH
SAQGPQMGIPQMIQSRAQFGSLGALLVVLIAGVMYIGFFASNIVLAGKSLHGLVDSVPVPVGIVIGALGSGIIGIIGYRF
IHVLNRIGTWVLGIGIVVGFGYILTHIQTDDFLTRGSFNLSGWLATVSLAALWQIAFAPYVSDYSRYLPANVPVAATFWT
TYLGSALGSSLSFVFGAVAVLATPVGMDTMDAVKLATGAIGPLMLVLFLLSVISHNALNLYGAVLSLITLVQTFAYRWIP
TAKSRAVISIIVLLACCFAAVGASADFIGHFVDMVLVLLVVLVPWTAINLIDFYAIHKGQYDIGSIFQVDGGIYGRYNPQ
ALLAYAIGIAVQIPFMNTPLYVGPVSAHINGADLSWLVGLLVTSPLYFWLATRDSAYRRRLTSGKLANNL

Specific function: Unknown

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320903, Length=353, Percent_Identity=24.3626062322946, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320897, Length=346, Percent_Identity=23.4104046242775, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320902, Length=372, Percent_Identity=24.1935483870968, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 50123; Mature: 49992

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEECCCCCCCCCHHHHHHHHHHHCCHHEEEECCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ATSATTSAPLIEKHTIGYVPPEDRHGKVRDLFTLWFGGNIAPLPIVTGALGVQLFHLNL
CCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH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EEEECCCCCCCCCHHHHHHHHHHHCCHHEEEECCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]