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The map label for this gene is argE [H]

Identifier: 77459491

GI number: 77459491

Start: 3750639

End: 3751787

Strand: Direct

Name: argE [H]

Synonym: Pfl01_3269

Alternate gene names: 77459491

Gene position: 3750639-3751787 (Clockwise)

Preceding gene: 77459490

Following gene: 77459492

Centisome position: 58.25

GC content: 63.45

Gene sequence:

>1149_bases
ATGAGCGACAGCGTCGCGTTGCTCAAGACGCTGGTGGAGTTCGACACCACCAGCCGCGAGTCCAACCTGCAATTGATCGA
CTTCGTGCGCAGCTACCTCGAAGGTTTCGATGTGCCGTGCGAGTTGATCTACAACGATGAGCGCAGCAAGGCCAATCTGT
TCGCCACGATCGGCCCGGCCGATCAACCGGGCATCGTGTTGTCGGGGCACACCGATGTGGTGCCCGCCGATGGCCAGCCG
TGGACGCTGCCGCCGTTCGAACTCAGCGAGCGCGACGGCAAGCTTTACGGTCGTGGCACCGCAGACATGAAAGGCTACAT
CGCCTGCGTGCTGGCGCTGGTGCCGTCGTTGATCGAAGCACCGCTGCGCCTGCCGGTGCACATTGCCCTGTCGTACGACG
AAGAAGTCGGCTGCCTCGGTGTGCGCTCGCTGCTCAAGGTGCTGGAGCAACGTCCGGTCAAACCGCTGCTGTGCATCATC
GGCGAGCCGACCGAGCTCAAACCGGTACTCGGGCACAAAGGCAAACTGGCGATGCGCTGCGATGTCCAGGGTCACGCCTG
TCACTCGGCTTACGCGCCGCTCGGAGTGAACGCCATCGAATGCGCCGCCGAGCTGATCGGCGAGCTCGGACGTATCGGCC
GGCAGCTCAAGGACGAACACGTCGATCCGCGTTTCGACCCGCCGTATTCCACGGTGCAAACCGGCGTAATCGGCGGTGGC
AAGGCGTTGAACATCGTCCCCGCCGATTGCCGTTTCGACTTCGAAATCCGCGCCCTGCCCTCGCAGGATCCGGCGGTCGT
TGCGCGGCAACTCAAGGCCTACGCCGAGCAGCAAATGCTACCGCGCATGCGGGCGGTCAGCGAGCAGAGCGATATCCGTT
TCAGTGAATTGTCGGCCTATCCGGGGCTGGCCACCGATGCCCGAAGCCAGGCTGCGCAATTGATCGCCACGTTCTGCGGT
TCGGACGATTTCGGCACTGTTGCGTTTGGGACCGAAGGCGGCTTGTTCGACGCAGTGGGGATTCCCACGGTGGTGTGCGG
TCCCGGCAGCATGGATCAGGGGCACAAGCCGGACGAGTTCGTCAGCATCGATCAGCTCACGGCCTGCGATGCGATGCTGC
AACGGATGCTGGCGTCGATCCGCCTCTGA

Upstream 100 bases:

>100_bases
AAAAACTCTGGGACGCCTATTGCCCGCAGCTTCAGGACTACATCGACCGCGCCCTCGATCCGGCCAAGGCGCCGGGCTAC
GGAGTTGCCGGAGACGACCG

Downstream 100 bases:

>100_bases
AAAAACGGCCTGGCTGCTGGATTCAGGTCTGCATCCGAGCCGCAATAACACCGACAGACAGCTGCTCCGATGGAGGTCAG
CTGCGTTGTCGTTCATGGTG

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSDSVALLKTLVEFDTTSRESNLQLIDFVRSYLEGFDVPCELIYNDERSKANLFATIGPADQPGIVLSGHTDVVPADGQP
WTLPPFELSERDGKLYGRGTADMKGYIACVLALVPSLIEAPLRLPVHIALSYDEEVGCLGVRSLLKVLEQRPVKPLLCII
GEPTELKPVLGHKGKLAMRCDVQGHACHSAYAPLGVNAIECAAELIGELGRIGRQLKDEHVDPRFDPPYSTVQTGVIGGG
KALNIVPADCRFDFEIRALPSQDPAVVARQLKAYAEQQMLPRMRAVSEQSDIRFSELSAYPGLATDARSQAAQLIATFCG
SDDFGTVAFGTEGGLFDAVGIPTVVCGPGSMDQGHKPDEFVSIDQLTACDAMLQRMLASIRL

Sequences:

>Translated_382_residues
MSDSVALLKTLVEFDTTSRESNLQLIDFVRSYLEGFDVPCELIYNDERSKANLFATIGPADQPGIVLSGHTDVVPADGQP
WTLPPFELSERDGKLYGRGTADMKGYIACVLALVPSLIEAPLRLPVHIALSYDEEVGCLGVRSLLKVLEQRPVKPLLCII
GEPTELKPVLGHKGKLAMRCDVQGHACHSAYAPLGVNAIECAAELIGELGRIGRQLKDEHVDPRFDPPYSTVQTGVIGGG
KALNIVPADCRFDFEIRALPSQDPAVVARQLKAYAEQQMLPRMRAVSEQSDIRFSELSAYPGLATDARSQAAQLIATFCG
SDDFGTVAFGTEGGLFDAVGIPTVVCGPGSMDQGHKPDEFVSIDQLTACDAMLQRMLASIRL
>Mature_381_residues
SDSVALLKTLVEFDTTSRESNLQLIDFVRSYLEGFDVPCELIYNDERSKANLFATIGPADQPGIVLSGHTDVVPADGQPW
TLPPFELSERDGKLYGRGTADMKGYIACVLALVPSLIEAPLRLPVHIALSYDEEVGCLGVRSLLKVLEQRPVKPLLCIIG
EPTELKPVLGHKGKLAMRCDVQGHACHSAYAPLGVNAIECAAELIGELGRIGRQLKDEHVDPRFDPPYSTVQTGVIGGGK
ALNIVPADCRFDFEIRALPSQDPAVVARQLKAYAEQQMLPRMRAVSEQSDIRFSELSAYPGLATDARSQAAQLIATFCGS
DDFGTVAFGTEGGLFDAVGIPTVVCGPGSMDQGHKPDEFVSIDQLTACDAMLQRMLASIRL

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=347, Percent_Identity=35.1585014409222, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1788816, Length=241, Percent_Identity=28.6307053941909, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789236, Length=335, Percent_Identity=23.2835820895522, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551016, Length=384, Percent_Identity=26.3020833333333, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17563146, Length=154, Percent_Identity=31.1688311688312, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 41241; Mature: 41110

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSVALLKTLVEFDTTSRESNLQLIDFVRSYLEGFDVPCELIYNDERSKANLFATIGPA
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCC
DQPGIVLSGHTDVVPADGQPWTLPPFELSERDGKLYGRGTADMKGYIACVLALVPSLIEA
CCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHC
PLRLPVHIALSYDEEVGCLGVRSLLKVLEQRPVKPLLCIIGEPTELKPVLGHKGKLAMRC
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCCCEEEEE
DVQGHACHSAYAPLGVNAIECAAELIGELGRIGRQLKDEHVDPRFDPPYSTVQTGVIGGG
CCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCC
KALNIVPADCRFDFEIRALPSQDPAVVARQLKAYAEQQMLPRMRAVSEQSDIRFSELSAY
CEEEEEECCCEECEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHCC
PGLATDARSQAAQLIATFCGSDDFGTVAFGTEGGLFDAVGIPTVVCGPGSMDQGHKPDEF
CCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEECCCCCEEEECCCCCCCCCCCCHH
VSIDQLTACDAMLQRMLASIRL
CCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDSVALLKTLVEFDTTSRESNLQLIDFVRSYLEGFDVPCELIYNDERSKANLFATIGPA
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCC
DQPGIVLSGHTDVVPADGQPWTLPPFELSERDGKLYGRGTADMKGYIACVLALVPSLIEA
CCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHC
PLRLPVHIALSYDEEVGCLGVRSLLKVLEQRPVKPLLCIIGEPTELKPVLGHKGKLAMRC
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCCCEEEEE
DVQGHACHSAYAPLGVNAIECAAELIGELGRIGRQLKDEHVDPRFDPPYSTVQTGVIGGG
CCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCC
KALNIVPADCRFDFEIRALPSQDPAVVARQLKAYAEQQMLPRMRAVSEQSDIRFSELSAY
CEEEEEECCCEECEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHCC
PGLATDARSQAAQLIATFCGSDDFGTVAFGTEGGLFDAVGIPTVVCGPGSMDQGHKPDEF
CCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEECCCCCEEEECCCCCCCCCCCCHH
VSIDQLTACDAMLQRMLASIRL
CCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]