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The map label for this gene is ttuB [H]

Identifier: 77459448

GI number: 77459448

Start: 3706341

End: 3707663

Strand: Reverse

Name: ttuB [H]

Synonym: Pfl01_3226

Alternate gene names: 77459448

Gene position: 3707663-3706341 (Counterclockwise)

Preceding gene: 77459451

Following gene: 77459447

Centisome position: 57.59

GC content: 62.21

Gene sequence:

>1323_bases
ATGAGCCAGGAACTGCGGCTTGTCCGGCGCATCACGCTGAAACTGATTCCCTTCCTGATCCTGCTGTACCTGATCGCCTA
TGTGGATCGCTCCGCCGTCGGCTTCGCCAAGCTGCACATGGGCGCCGACATCGGCATCGGCGATGCCGCCTACGGCCTTG
GCGCCGGGCTGTTTTTCATCGGCTACTTTCTGTTTGAAATCCCTAGCAACCTGATGCTCGAACGCTTCGGCGCGCGGCGC
TGGTTCGCGCGGATCATGATCACCTGGGGCGCGATCACCATCGGCATGGCGTTCGTCCAGGGCCCGCACAGTTTCTACGT
GATGCGGTTTCTGCTCGGTGCGGCGGAGGCGGGGTTCTTTCCCGGCGTTCTGTACTACATCACTCAGTGGTTCCCGGTGC
GTCATCGCGGCAAGATCCTCGGGCTGTTCATCCTGTCCCAACCCATCGCGATGATGATCACCGGCCCTGTCTCGGGAGGC
CTGCTGGGCATGGACGGCATCCTCGGCCTGCACGGCTGGCAATGGCTGTTCATCGTCATCGGCACCCCGGCGATCTTGCT
GACCTGGCCGGTATTGCGCTGGCTGCCGGACGGCCCGCAGCAAGTGAAATGGATGGACCAGGCCGAGAAGGACTGGTTGA
CCGGCGAGCTGAAAAAGGACCTGCAGGAATACGGCCAGACCCGTCACGGCAATCCGCTGCATGCGTTGAAAGACAAACGT
GTGTTGCTGCTGGCGCTGTTCTATCTGCCGGTGACCCTGAGCATTTATGGCCTGGGCCTGTGGCTGCCGACCCTGATCAA
ACAGTTCGGCGGCAGCGATCTGGTGACCGGTTTCGTGTCATCGGTGCCGTACATCTTCGGGATCATCGGCCTGCTGATCA
TTCCGCGCAGTTCCGACCGTTTGAACGACCGCTACGGCCATCTGGCGGTGCTCTATGTGCTGGGTGCCATGGGCCTGTTC
CTCAGTGCCTGGCTGTCGTTGCCGGTGGCGCAACTGGCAGCGTTGTGTCTGGTGGCGTTCGCGCTGTTTTCCTGCACAGC
GGTGTTCTGGACTTTGCCGGGACGGTTCTTTGCCGGTGCCAGTGCGGCGGCCGGGATTGCCTTGATCAACTCGGTGGGCA
ACCTCGGCGGCTACATCGGCCCGTTCGTGATCGGCGCCTTGAAGGAATACACCGGCAACCTTGCTTCGGGCCTGTACTTC
CTGTCCGGGGTGATGGTGTGCGGGCTGATTCTGACGGGCGTCGTCTATCGCTTGCTCGAGCGCAAGCATGTGCTGCCAGT
CGAGCAATTTGCAGCGAGCGCGCGCGGCGCGACGCGCACCTGA

Upstream 100 bases:

>100_bases
ATTACTATATAGTCGATTTCGACGGAGGGATGGCCCTGGCGGTTTTCTGCGAGAGGCGTCCCCCGAGGTTCCATAAAAAC
AACAATCGGAGACCGATCTC

Downstream 100 bases:

>100_bases
TTTCGATCCGGGATTTGTTTTAACAGGAGAACATCATGCATCTGGTTCAATTCGAATTGAGTAGCGGCGAGCGCCGTGTC
GGGGTGGTCGAGGGCGGTCT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSQELRLVRRITLKLIPFLILLYLIAYVDRSAVGFAKLHMGADIGIGDAAYGLGAGLFFIGYFLFEIPSNLMLERFGARR
WFARIMITWGAITIGMAFVQGPHSFYVMRFLLGAAEAGFFPGVLYYITQWFPVRHRGKILGLFILSQPIAMMITGPVSGG
LLGMDGILGLHGWQWLFIVIGTPAILLTWPVLRWLPDGPQQVKWMDQAEKDWLTGELKKDLQEYGQTRHGNPLHALKDKR
VLLLALFYLPVTLSIYGLGLWLPTLIKQFGGSDLVTGFVSSVPYIFGIIGLLIIPRSSDRLNDRYGHLAVLYVLGAMGLF
LSAWLSLPVAQLAALCLVAFALFSCTAVFWTLPGRFFAGASAAAGIALINSVGNLGGYIGPFVIGALKEYTGNLASGLYF
LSGVMVCGLILTGVVYRLLERKHVLPVEQFAASARGATRT

Sequences:

>Translated_440_residues
MSQELRLVRRITLKLIPFLILLYLIAYVDRSAVGFAKLHMGADIGIGDAAYGLGAGLFFIGYFLFEIPSNLMLERFGARR
WFARIMITWGAITIGMAFVQGPHSFYVMRFLLGAAEAGFFPGVLYYITQWFPVRHRGKILGLFILSQPIAMMITGPVSGG
LLGMDGILGLHGWQWLFIVIGTPAILLTWPVLRWLPDGPQQVKWMDQAEKDWLTGELKKDLQEYGQTRHGNPLHALKDKR
VLLLALFYLPVTLSIYGLGLWLPTLIKQFGGSDLVTGFVSSVPYIFGIIGLLIIPRSSDRLNDRYGHLAVLYVLGAMGLF
LSAWLSLPVAQLAALCLVAFALFSCTAVFWTLPGRFFAGASAAAGIALINSVGNLGGYIGPFVIGALKEYTGNLASGLYF
LSGVMVCGLILTGVVYRLLERKHVLPVEQFAASARGATRT
>Mature_439_residues
SQELRLVRRITLKLIPFLILLYLIAYVDRSAVGFAKLHMGADIGIGDAAYGLGAGLFFIGYFLFEIPSNLMLERFGARRW
FARIMITWGAITIGMAFVQGPHSFYVMRFLLGAAEAGFFPGVLYYITQWFPVRHRGKILGLFILSQPIAMMITGPVSGGL
LGMDGILGLHGWQWLFIVIGTPAILLTWPVLRWLPDGPQQVKWMDQAEKDWLTGELKKDLQEYGQTRHGNPLHALKDKRV
LLLALFYLPVTLSIYGLGLWLPTLIKQFGGSDLVTGFVSSVPYIFGIIGLLIIPRSSDRLNDRYGHLAVLYVLGAMGLFL
SAWLSLPVAQLAALCLVAFALFSCTAVFWTLPGRFFAGASAAAGIALINSVGNLGGYIGPFVIGALKEYTGNLASGLYFL
SGVMVCGLILTGVVYRLLERKHVLPVEQFAASARGATRT

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=422, Percent_Identity=36.0189573459716, Blast_Score=281, Evalue=6e-77,
Organism=Escherichia coli, GI1789152, Length=427, Percent_Identity=24.3559718969555, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082320, Length=439, Percent_Identity=26.4236902050114, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789515, Length=449, Percent_Identity=24.7216035634744, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI2367379, Length=436, Percent_Identity=22.0183486238532, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322025, Length=183, Percent_Identity=27.8688524590164, Blast_Score=83, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6321698, Length=305, Percent_Identity=22.6229508196721, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322612, Length=285, Percent_Identity=21.7543859649123, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319876, Length=177, Percent_Identity=29.3785310734463, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322973, Length=381, Percent_Identity=21.7847769028871, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48287; Mature: 48156

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQELRLVRRITLKLIPFLILLYLIAYVDRSAVGFAKLHMGADIGIGDAAYGLGAGLFFI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
GYFLFEIPSNLMLERFGARRWFARIMITWGAITIGMAFVQGPHSFYVMRFLLGAAEAGFF
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
PGVLYYITQWFPVRHRGKILGLFILSQPIAMMITGPVSGGLLGMDGILGLHGWQWLFIVI
HHHHHHHHHHCCCCCCCCEEEHHHHHCCHHEEEECCCCCCCCCCCHHHHCCCHHEEEEEE
GTPAILLTWPVLRWLPDGPQQVKWMDQAEKDWLTGELKKDLQEYGQTRHGNPLHALKDKR
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCH
VLLLALFYLPVTLSIYGLGLWLPTLIKQFGGSDLVTGFVSSVPYIFGIIGLLIIPRSSDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LNDRYGHLAVLYVLGAMGLFLSAWLSLPVAQLAALCLVAFALFSCTAVFWTLPGRFFAGA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
SAAAGIALINSVGNLGGYIGPFVIGALKEYTGNLASGLYFLSGVMVCGLILTGVVYRLLE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKHVLPVEQFAASARGATRT
HCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
SQELRLVRRITLKLIPFLILLYLIAYVDRSAVGFAKLHMGADIGIGDAAYGLGAGLFFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
GYFLFEIPSNLMLERFGARRWFARIMITWGAITIGMAFVQGPHSFYVMRFLLGAAEAGFF
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
PGVLYYITQWFPVRHRGKILGLFILSQPIAMMITGPVSGGLLGMDGILGLHGWQWLFIVI
HHHHHHHHHHCCCCCCCCEEEHHHHHCCHHEEEECCCCCCCCCCCHHHHCCCHHEEEEEE
GTPAILLTWPVLRWLPDGPQQVKWMDQAEKDWLTGELKKDLQEYGQTRHGNPLHALKDKR
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCH
VLLLALFYLPVTLSIYGLGLWLPTLIKQFGGSDLVTGFVSSVPYIFGIIGLLIIPRSSDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LNDRYGHLAVLYVLGAMGLFLSAWLSLPVAQLAALCLVAFALFSCTAVFWTLPGRFFAGA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
SAAAGIALINSVGNLGGYIGPFVIGALKEYTGNLASGLYFLSGVMVCGLILTGVVYRLLE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKHVLPVEQFAASARGATRT
HCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]