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The map label for this gene is rsbS [H]

Identifier: 77459356

GI number: 77459356

Start: 3597200

End: 3597562

Strand: Direct

Name: rsbS [H]

Synonym: Pfl01_3134

Alternate gene names: 77459356

Gene position: 3597200-3597562 (Clockwise)

Preceding gene: 77459355

Following gene: 77459357

Centisome position: 55.87

GC content: 59.5

Gene sequence:

>363_bases
ATGGAACGTATCCCGATTCTTCAGATGGGTGACTTCCTGCTGGTGACCATCCAGGTCGACATGCATGACCAACTCGCCCT
CACCCTGCAAGACGACCTGTCCGAGCGCATCAGCAAGACCTCCGCGCGCGGCGTGCTGATCGACATCTCGGCGCTGGACA
TGGTCGATTCGTTCATCGGCCGTATGATCGGCACCATTTCCGGCCTGTCGAAAATCATGGACGCTGAAACCATGCTGGTC
GGTATGCAACCGGCAGTAGCGATCACGCTGGTGGAGCTCGGCCTGTACCTGCCGGGCGTCAGCACCGCGCTGAACGTCGA
GCGCGGAATGAAACTGCTGCAGGAACGAGTACGCCAGCAATGA

Upstream 100 bases:

>100_bases
CCTGGATCTGCAGGGTGTGGTCACCAAAGCCAATCTGGCCGACGCACTGAAGCTGGCCCTGACCCGTCTGGGCATCACCC
TCACCAAGACGGTCTGAACA

Downstream 100 bases:

>100_bases
CCGTGCGCAGCAGCGGTACCCAACCGATCAACATCGAGCAGGATGTGGTGCTGGCGCGGCAAACGGCGCGCAAGCTGGCC
ACCGAGTGCGGCATGCGCCT

Product: anti-sigma-factor antagonist (STAS)

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MERIPILQMGDFLLVTIQVDMHDQLALTLQDDLSERISKTSARGVLIDISALDMVDSFIGRMIGTISGLSKIMDAETMLV
GMQPAVAITLVELGLYLPGVSTALNVERGMKLLQERVRQQ

Sequences:

>Translated_120_residues
MERIPILQMGDFLLVTIQVDMHDQLALTLQDDLSERISKTSARGVLIDISALDMVDSFIGRMIGTISGLSKIMDAETMLV
GMQPAVAITLVELGLYLPGVSTALNVERGMKLLQERVRQQ
>Mature_120_residues
MERIPILQMGDFLLVTIQVDMHDQLALTLQDDLSERISKTSARGVLIDISALDMVDSFIGRMIGTISGLSKIMDAETMLV
GMQPAVAITLVELGLYLPGVSTALNVERGMKLLQERVRQQ

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 13201; Mature: 13201

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.5 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.5 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIPILQMGDFLLVTIQVDMHDQLALTLQDDLSERISKTSARGVLIDISALDMVDSFIG
CCCCCEEEECCEEEEEEEECCCCCEEEHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHH
RMIGTISGLSKIMDAETMLVGMQPAVAITLVELGLYLPGVSTALNVERGMKLLQERVRQQ
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERIPILQMGDFLLVTIQVDMHDQLALTLQDDLSERISKTSARGVLIDISALDMVDSFIG
CCCCCEEEECCEEEEEEEECCCCCEEEHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHH
RMIGTISGLSKIMDAETMLVGMQPAVAITLVELGLYLPGVSTALNVERGMKLLQERVRQQ
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]