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The map label for this gene is btuB [H]

Identifier: 77459343

GI number: 77459343

Start: 3580943

End: 3583597

Strand: Reverse

Name: btuB [H]

Synonym: Pfl01_3121

Alternate gene names: 77459343

Gene position: 3583597-3580943 (Counterclockwise)

Preceding gene: 77459344

Following gene: 77459342

Centisome position: 55.66

GC content: 61.36

Gene sequence:

>2655_bases
ATGATCCATTTTTCACCCGTTAAATCCCCTTTGAGCCTGGCCTTGCTGCTGGCGATCAACACATTGCCGGCGATTGCTGC
CGACAGCAGTGCGACAGAACCGACCACCCAGTTGCAACGGATCGAAGTCACCGGCACCGCGATTCGCCGGGTCGATGCCG
AAACGGCAGTGCCGGTGACCATCCTTCGGGTGGAAGAACTGCAGAAGCAAGGTGTGACAACGACTGAAGAGCTGGTCAGC
CGTATCTCTGCCAACCAGTCGTCCGTAGGCTCCGGGCGTTCGGTGGGTTCTTCCAGCGGCGGCGCGTCTTATGCGGACTT
GCGTGGCATCGGCCCGAACAAGACTTTGGTGCTGCTCAACGGTCGGCGTCTGAGCAACAACGCGACCAATGCGATCAATG
GCTCTGGCGTCGACCTCAACACCATCCCGTTCGCCGCCATCGACCGGGTGGAGGTGCTGCGCGACGGCGCCTCGGCGTTG
TATGGCACCGATGCCATCGGTGGGGTGATCAACTTCATCACCAAGACCAGCCTCACCGAAGGCCAGATCAGCACCAATTA
CGATACGCCGACCCATTCCGGTGGCGGTGAAAGCCGCAACTTCAGCGGCAGCTGGGGTTTTGGTGATTTGCAGGACGATC
GCTTCAACGTTTTCGGCGTGGTGAGCTACGACAAGCAGAATCGCCTGGCGGCCGACGATCGCGGCTACACCTATAACTAC
CAGCCGGGACGCGGACTCGATTACACCTCCGGCACGGCATCGCCCGCCAACTGGAGCCAGGGCAGTAACGCCACCAACCC
GCTGGCCGGTTCCGGTTGCAATGCGCCGGGGCTGTTGTCACGCAACGGCATCTGCCGCCAGAGCCTGTGGAATTACCTGG
ATCTGGTGCCGGAAACCGAAAAGACCTCCGCGTTCGCCAAGGCCACCGGCAAGCTGTCGGATGATCACAACGTCAGCCTC
GAATACTTCTGGGCGCGCAACGAAAACCGGACGCAGATCGGCCCCGGCACTTTGATGGGCAATCAGGTCAATCCTGGCAC
GGCGTTCTATCCGGGTAACGGCATTACGCCCGGCCCGAGCGGTTTCGCCCTCGACCCGACGCAACCGGTGGACGTGAATT
GGCGTGAAACTGCCGTCGGTGCCCGGCAGCATGAAGATGACAACACGGGTCAGCGCCTGCTGTTGAGCTTCGATGGCACG
CTGGTGGGGTGGGATTACAACCTCGGCGCGTCGTACAACCAGAACAAGGTGGTCAACACGATTCGCAGCGGTTACGTGAA
CGACCGTGCCGTCAGCCAGGGCATCGCCAACGGTGTGATCAACCCGTTCGGTCCGCAGACGGCTGCCGGTTCAGCATTGT
TAGCGGACAATGAGGTAGACGGCGATTACGCAACGGCAGTGGGCCGGGTCAAGGCGATTGACGGGCGCATCAGCCGCGAG
ATCGGCGACTGGTTCGGTGCAGGGCCTTCGGCGCTGGCGCTGGGCGGTGAATACCGCAAGGAAGATTTCCACCAGGATTT
CGCCGCGTTTGCCGGCGACGTGCAGAGCCTGGGTGTTGATCCCAATGGCAGCGTAAAAGGGGATCGCAGCGTCTCGGCCC
AGTACGCCGAGGTCAACGTGCCGGTGTTCGACAGCCTTGAATTATCCGCCGCCGTGCGCCACGACAAATACAGCGACTTT
GGCAGCACCACCAACCCGAAATACTCGTTCCGCTTCCAGCCGTTCAAGGAGCTGGTGGTGCGTGGTGCCTACAGTGAAGG
CTTCCGTGCGCCGTCGCTTTATGAGTTGTACAACCCGACGTTTACCTCGTTCACCAATGCCAACTACAACGACCCGCGCC
TGTGCGCCGGTGGCAACCCGAGCAACGGCGGGATCGCCAACCGCGACTGCGCCCAGCAGTTCAATCGCACCTCCGGCGGC
AACACCGACCTGAGCCCGGAAACCGCACGCAACGTCACCCTCGGTTTCGTTTATCAGCCGTTTGATCGACTGACCACCGG
GCTGGATTTCTGGTGGATTGACATCGCCAACCAGATCGCCGAATTCCCCGAATCGGCGGTGTTCGAGAACCCGGAGCTGT
ACCCGGAGCGCCTGATCCGCAAGCCTGATGGCTCCATCGATCACATCGTCACCGGCCTGGCCAACCTCGGCAAGATCAAG
ACCAACGGCGTCGACGTGAGCTTCGACTATCGCCTGCCGAGCACACCGTACGGCGATTTCGGCATCGGTCTGCAAGGCAC
TTACGTCACCCGTTACGACTATCAGCAGCAGCTCAAGGGCGACTACATCGACAAGCTCGGCGATTTTCGTGGCGGCGACT
TTGCCTCGGCCGGCGCCGTGGCCCGTTGGCGTCACAGCCTGACCGGCAGCTGGAACTACGGTCCGTTCGGTGCCAGCCTG
ACCAACCGCTACACCAGCGGTTACCACGACTCGGATCGCGAGACTCACGATTACGTCGGCTCGTACAACGTCTGGGACGT
GGCCGGCACCTACACCTGGCGTAAGACCCTGGCGGTGACCCTCGGGGTGAAAAACCTGTTCGACCGCGAGCCGCCATTCA
GCAACCAGACCTACACGTTCCAGAGCGGCTACGACCCGAAATACGGCGACCCGTTTGGCCGCACGCTGTACACGCGGATC
AATTACAAGTTCTGA

Upstream 100 bases:

>100_bases
TTTGCATAACCTCAGCACCCAACGGTCTAAATCGCGCCCTATAAATCGTCATCCGCCATCGCACATCCCTGCATAAACCA
AAACGCAGGGATGGCTGTTC

Downstream 100 bases:

>100_bases
GAAAGATAGGTCGGGGCGGGTTTTAGTAACACATCGTTCTAACCCCCGCCCTATAAAAAGGCCCGGCCTGTTGCACTTCA
CCATCAGGCAGGCACGTGGT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 884; Mature: 884

Protein sequence:

>884_residues
MIHFSPVKSPLSLALLLAINTLPAIAADSSATEPTTQLQRIEVTGTAIRRVDAETAVPVTILRVEELQKQGVTTTEELVS
RISANQSSVGSGRSVGSSSGGASYADLRGIGPNKTLVLLNGRRLSNNATNAINGSGVDLNTIPFAAIDRVEVLRDGASAL
YGTDAIGGVINFITKTSLTEGQISTNYDTPTHSGGGESRNFSGSWGFGDLQDDRFNVFGVVSYDKQNRLAADDRGYTYNY
QPGRGLDYTSGTASPANWSQGSNATNPLAGSGCNAPGLLSRNGICRQSLWNYLDLVPETEKTSAFAKATGKLSDDHNVSL
EYFWARNENRTQIGPGTLMGNQVNPGTAFYPGNGITPGPSGFALDPTQPVDVNWRETAVGARQHEDDNTGQRLLLSFDGT
LVGWDYNLGASYNQNKVVNTIRSGYVNDRAVSQGIANGVINPFGPQTAAGSALLADNEVDGDYATAVGRVKAIDGRISRE
IGDWFGAGPSALALGGEYRKEDFHQDFAAFAGDVQSLGVDPNGSVKGDRSVSAQYAEVNVPVFDSLELSAAVRHDKYSDF
GSTTNPKYSFRFQPFKELVVRGAYSEGFRAPSLYELYNPTFTSFTNANYNDPRLCAGGNPSNGGIANRDCAQQFNRTSGG
NTDLSPETARNVTLGFVYQPFDRLTTGLDFWWIDIANQIAEFPESAVFENPELYPERLIRKPDGSIDHIVTGLANLGKIK
TNGVDVSFDYRLPSTPYGDFGIGLQGTYVTRYDYQQQLKGDYIDKLGDFRGGDFASAGAVARWRHSLTGSWNYGPFGASL
TNRYTSGYHDSDRETHDYVGSYNVWDVAGTYTWRKTLAVTLGVKNLFDREPPFSNQTYTFQSGYDPKYGDPFGRTLYTRI
NYKF

Sequences:

>Translated_884_residues
MIHFSPVKSPLSLALLLAINTLPAIAADSSATEPTTQLQRIEVTGTAIRRVDAETAVPVTILRVEELQKQGVTTTEELVS
RISANQSSVGSGRSVGSSSGGASYADLRGIGPNKTLVLLNGRRLSNNATNAINGSGVDLNTIPFAAIDRVEVLRDGASAL
YGTDAIGGVINFITKTSLTEGQISTNYDTPTHSGGGESRNFSGSWGFGDLQDDRFNVFGVVSYDKQNRLAADDRGYTYNY
QPGRGLDYTSGTASPANWSQGSNATNPLAGSGCNAPGLLSRNGICRQSLWNYLDLVPETEKTSAFAKATGKLSDDHNVSL
EYFWARNENRTQIGPGTLMGNQVNPGTAFYPGNGITPGPSGFALDPTQPVDVNWRETAVGARQHEDDNTGQRLLLSFDGT
LVGWDYNLGASYNQNKVVNTIRSGYVNDRAVSQGIANGVINPFGPQTAAGSALLADNEVDGDYATAVGRVKAIDGRISRE
IGDWFGAGPSALALGGEYRKEDFHQDFAAFAGDVQSLGVDPNGSVKGDRSVSAQYAEVNVPVFDSLELSAAVRHDKYSDF
GSTTNPKYSFRFQPFKELVVRGAYSEGFRAPSLYELYNPTFTSFTNANYNDPRLCAGGNPSNGGIANRDCAQQFNRTSGG
NTDLSPETARNVTLGFVYQPFDRLTTGLDFWWIDIANQIAEFPESAVFENPELYPERLIRKPDGSIDHIVTGLANLGKIK
TNGVDVSFDYRLPSTPYGDFGIGLQGTYVTRYDYQQQLKGDYIDKLGDFRGGDFASAGAVARWRHSLTGSWNYGPFGASL
TNRYTSGYHDSDRETHDYVGSYNVWDVAGTYTWRKTLAVTLGVKNLFDREPPFSNQTYTFQSGYDPKYGDPFGRTLYTRI
NYKF
>Mature_884_residues
MIHFSPVKSPLSLALLLAINTLPAIAADSSATEPTTQLQRIEVTGTAIRRVDAETAVPVTILRVEELQKQGVTTTEELVS
RISANQSSVGSGRSVGSSSGGASYADLRGIGPNKTLVLLNGRRLSNNATNAINGSGVDLNTIPFAAIDRVEVLRDGASAL
YGTDAIGGVINFITKTSLTEGQISTNYDTPTHSGGGESRNFSGSWGFGDLQDDRFNVFGVVSYDKQNRLAADDRGYTYNY
QPGRGLDYTSGTASPANWSQGSNATNPLAGSGCNAPGLLSRNGICRQSLWNYLDLVPETEKTSAFAKATGKLSDDHNVSL
EYFWARNENRTQIGPGTLMGNQVNPGTAFYPGNGITPGPSGFALDPTQPVDVNWRETAVGARQHEDDNTGQRLLLSFDGT
LVGWDYNLGASYNQNKVVNTIRSGYVNDRAVSQGIANGVINPFGPQTAAGSALLADNEVDGDYATAVGRVKAIDGRISRE
IGDWFGAGPSALALGGEYRKEDFHQDFAAFAGDVQSLGVDPNGSVKGDRSVSAQYAEVNVPVFDSLELSAAVRHDKYSDF
GSTTNPKYSFRFQPFKELVVRGAYSEGFRAPSLYELYNPTFTSFTNANYNDPRLCAGGNPSNGGIANRDCAQQFNRTSGG
NTDLSPETARNVTLGFVYQPFDRLTTGLDFWWIDIANQIAEFPESAVFENPELYPERLIRKPDGSIDHIVTGLANLGKIK
TNGVDVSFDYRLPSTPYGDFGIGLQGTYVTRYDYQQQLKGDYIDKLGDFRGGDFASAGAVARWRHSLTGSWNYGPFGASL
TNRYTSGYHDSDRETHDYVGSYNVWDVAGTYTWRKTLAVTLGVKNLFDREPPFSNQTYTFQSGYDPKYGDPFGRTLYTRI
NYKF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=177, Percent_Identity=28.8135593220339, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786798, Length=213, Percent_Identity=30.5164319248826, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790405, Length=195, Percent_Identity=28.7179487179487, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 95846; Mature: 95846

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHFSPVKSPLSLALLLAINTLPAIAADSSATEPTTQLQRIEVTGTAIRRVDAETAVPVT
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEEEECCHHHHHCCCCCCCCEE
ILRVEELQKQGVTTTEELVSRISANQSSVGSGRSVGSSSGGASYADLRGIGPNKTLVLLN
EEEHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEE
GRRLSNNATNAINGSGVDLNTIPFAAIDRVEVLRDGASALYGTDAIGGVINFITKTSLTE
CEEECCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHCCCCC
GQISTNYDTPTHSGGGESRNFSGSWGFGDLQDDRFNVFGVVSYDKQNRLAADDRGYTYNY
CCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEC
QPGRGLDYTSGTASPANWSQGSNATNPLAGSGCNAPGLLSRNGICRQSLWNYLDLVPETE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCH
KTSAFAKATGKLSDDHNVSLEYFWARNENRTQIGPGTLMGNQVNPGTAFYPGNGITPGPS
HHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEECCCCEECCCCCCCCEEECCCCCCCCCC
GFALDPTQPVDVNWRETAVGARQHEDDNTGQRLLLSFDGTLVGWDYNLGASYNQNKVVNT
CCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCHHHHHH
IRSGYVNDRAVSQGIANGVINPFGPQTAAGSALLADNEVDGDYATAVGRVKAIDGRISRE
HHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHEEECCCHHHHH
IGDWFGAGPSALALGGEYRKEDFHQDFAAFAGDVQSLGVDPNGSVKGDRSVSAQYAEVNV
HHHHHCCCCCCEECCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCEEEEEECC
PVFDSLELSAAVRHDKYSDFGSTTNPKYSFRFQPFKELVVRGAYSEGFRAPSLYELYNPT
CCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHCCHHCCCCCCCHHHHCCCC
FTSFTNANYNDPRLCAGGNPSNGGIANRDCAQQFNRTSGGNTDLSPETARNVTLGFVYQP
CCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHCCEEEEEEECC
FDRLTTGLDFWWIDIANQIAEFPESAVFENPELYPERLIRKPDGSIDHIVTGLANLGKIK
HHHHHCCCCEEEHHHHHHHHHCCHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCEE
TNGVDVSFDYRLPSTPYGDFGIGLQGTYVTRYDYQQQLKGDYIDKLGDFRGGDFASAGAV
ECCEEEEEECCCCCCCCCCCCCCCCCEEEEECCHHHHHCHHHHHHHHCCCCCCCCCCCHH
ARWRHSLTGSWNYGPFGASLTNRYTSGYHDSDRETHDYVGSYNVWDVAGTYTWRKTLAVT
HHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHCCCCCEEECCCCEEEHEEEEEE
LGVKNLFDREPPFSNQTYTFQSGYDPKYGDPFGRTLYTRINYKF
ECHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MIHFSPVKSPLSLALLLAINTLPAIAADSSATEPTTQLQRIEVTGTAIRRVDAETAVPVT
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEEEECCHHHHHCCCCCCCCEE
ILRVEELQKQGVTTTEELVSRISANQSSVGSGRSVGSSSGGASYADLRGIGPNKTLVLLN
EEEHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEE
GRRLSNNATNAINGSGVDLNTIPFAAIDRVEVLRDGASALYGTDAIGGVINFITKTSLTE
CEEECCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHCCCCC
GQISTNYDTPTHSGGGESRNFSGSWGFGDLQDDRFNVFGVVSYDKQNRLAADDRGYTYNY
CCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEC
QPGRGLDYTSGTASPANWSQGSNATNPLAGSGCNAPGLLSRNGICRQSLWNYLDLVPETE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCH
KTSAFAKATGKLSDDHNVSLEYFWARNENRTQIGPGTLMGNQVNPGTAFYPGNGITPGPS
HHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEECCCCEECCCCCCCCEEECCCCCCCCCC
GFALDPTQPVDVNWRETAVGARQHEDDNTGQRLLLSFDGTLVGWDYNLGASYNQNKVVNT
CCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCHHHHHH
IRSGYVNDRAVSQGIANGVINPFGPQTAAGSALLADNEVDGDYATAVGRVKAIDGRISRE
HHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHEEECCCHHHHH
IGDWFGAGPSALALGGEYRKEDFHQDFAAFAGDVQSLGVDPNGSVKGDRSVSAQYAEVNV
HHHHHCCCCCCEECCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCEEEEEECC
PVFDSLELSAAVRHDKYSDFGSTTNPKYSFRFQPFKELVVRGAYSEGFRAPSLYELYNPT
CCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHCCHHCCCCCCCHHHHCCCC
FTSFTNANYNDPRLCAGGNPSNGGIANRDCAQQFNRTSGGNTDLSPETARNVTLGFVYQP
CCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHCCEEEEEEECC
FDRLTTGLDFWWIDIANQIAEFPESAVFENPELYPERLIRKPDGSIDHIVTGLANLGKIK
HHHHHCCCCEEEHHHHHHHHHCCHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCEE
TNGVDVSFDYRLPSTPYGDFGIGLQGTYVTRYDYQQQLKGDYIDKLGDFRGGDFASAGAV
ECCEEEEEECCCCCCCCCCCCCCCCCEEEEECCHHHHHCHHHHHHHHCCCCCCCCCCCHH
ARWRHSLTGSWNYGPFGASLTNRYTSGYHDSDRETHDYVGSYNVWDVAGTYTWRKTLAVT
HHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHCCCCCEEECCCCEEEHEEEEEE
LGVKNLFDREPPFSNQTYTFQSGYDPKYGDPFGRTLYTRINYKF
ECHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11598060 [H]