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The map label for this gene is zraS [C]

Identifier: 77459305

GI number: 77459305

Start: 3531893

End: 3534430

Strand: Direct

Name: zraS [C]

Synonym: Pfl01_3083

Alternate gene names: 77459305

Gene position: 3531893-3534430 (Clockwise)

Preceding gene: 77459302

Following gene: 77459306

Centisome position: 54.86

GC content: 62.17

Gene sequence:

>2538_bases
ATGAACGCTGTACCGAACACCAACGACGCCCAGACATTGATCGCCCGAACCGACTGGAGCCGCAGCCCGCTGGGCGCCGC
CGGCACCTGGCCTCAGAGCCTGCGCACCGCGGTGGACATCGTGCTTCACTCGCCGATGCCGATGCTGCTGTTGTGGGGCC
CGCAATTGACCCAGATCTACAACGACGGCTTCGCGCTGCTGGCCGGCAACAAGCATCCGCACGCTTTCGGACAACCAGCG
CACCAGATATGGCCGGAACTTCGAGACTTTACCGACCCTATTTACAGCGCCGTCCTACAGGGCCAGGTGCGAACCTACAG
CGAACGACGCTTCACCCTGCAACGGGACGGCCAGGAGTCCGACTTCTGGCTTGACCTGACCTACAGCCCGATCCGTGACG
AAAGCGCGCAGGTGGCCGGAATTTTGGTCACCGCCATCGAAACCAACGAACGTCGGCGCATTGCCCTGGAACTGCAACAG
CGCTCCGAAAACAGCCTCAAGGCCCAGCGCGAAAGCGAAGAGCGCCTGCAACTGGCGCTGGCAGCCACCGATGCGGTCGG
CACCTGGGATTGGGACATCGGCGAAGACCGCTTCATTGCCGACGCGCATTTCGCCCAGTTGCACGGTGTCGATCCGGCGC
TGGCCGGTCAGTTGCCGATCAGCGAGTATCTGCACGGCGTGCACCCCGAAGACCGCGCAATGATCGCCCGCAGTATCAAG
CATTGCATTACCCACGGCACCGAATACGCCGAGGAATACCGCCTGCTGCAGGCCAACGGCGAACTGCGCTGGGTGTTCGC
CCGCGGGCGTTGCTACAAGGATCATCATGGTCGGCCGACGCGCTTTCTCGGCGCTGCGCTGGATCTGACCGAACGCAAGC
ACACCGAACAGGCATTGCGGCAAAGTCAGACCGAGCTGCAACTGATCATCAACGCCATGCCGATCCTGATCAGTTATGTC
GACCACGAGGAACGCTTTCGCCTGAACAACGCCGCGTACCTCGACTGGTACGGGCTCACGCCGCAGGAGCTGTACGGTCG
CACGATCCGCGAGGTGATCGGCGAAGAGGCCTATTTCCTGCGGGCACCTTACATCGCCGAAGCACTCGCCGGTCGCCCCT
GCTCGTTCAGCCTGTACACGCCGCACCGCGACGGCAGCCAGCGGCATGCCTTGATGAATTACCTGCCGCGCCACGGTGCG
GACGGTGCAGTGAACGGTTTCTACATCTTCGTGATCGACGAAACCGAACGCAAAAAGACCGAAGAAGCCCTGCGCAACCT
CAATGAAACCCTTGAGGAGCGTGTGAGTGCGCGCACCGAACAACTGGCCCAGGCCAACCAGCGTTTGCAGAACGAAATGT
TCGAACGCGAGCGCGCCGAAGACGCTCTGCGTCACGCACAGAAAATGGAAGCGGTCGGCCAGCTCACCGGCGGCATCGCC
CACGACTTCAACAACATGCTGACCGGCATCATCGGCAGCCTCGACCTGATGCAACGCTACATCGCCAGTGGCCGCGCCGA
TGAGATCGGCCGTTTCACCGACGCGGCGGTGTCTTCGGCCAACCGCGCGGCGGCATTGACCCACCGTCTGCTGGCGTTCT
CCCGGCGTCAGTCGCTGGATCGCAAGACTATCGACGTCAATGAACTGATCCACTCGCTGGAAGACCTGATCCGCCGCACT
AAAGGTGATCCGATCGAGCTCAAGTTGCGCCTGGCCGACAATGTATGGCCGGTCAGCACCGATGTCAGCCAACTGGAAAA
CGCCCTGCTCAACCTGGTGATCAACGCCCGCGATGCCATGCCGGACGGCGGTGAACTACTGATCGAAACGGCCAACGTCT
ACCTCGACGGCAACGACATCACTACCCTCGAACCGGTCAAGGCCGGTGATTACCTGATGCTGGCGGTGAGCGACAACGGC
ACCGGCATGACGCCTTCAGTACGTTCCAAAGCGTTCGATCCGTTCTTTACGACCAAACCCATCGGGCAAGGCACCGGGCT
CGGCTTGTCGATGATTTATGGCTTTGCCCAGCAATCGGGAGGGCACGTCAGCCTCGACAGCCTGCCGGGCCAGGGCACCT
GCGTGCGCCTGTACTTGCCGCGTTTGTATGCACTGGAAGCGGAGCAGCCGGCAATCGAAGCGGTTGCCGAGGCTCCGGCT
GTCGCCACTGGCGAAACCGTGGTGGTGGTCGAGGACGATCCGGCAGTGCGCATGCTGGTCATGGACCTGCTCAAGGAGCT
GGGTTATCGCGCCCATGAGGCCGAAGACGCCAAGGGTGCCTTGCCGCTACTGGAATCCGACCTGCGGGTGGACTTGCTGG
TGACCGACGTCGGCCTGCCGGGCATGAACGGCCGGCAAATGGCGGAGATCGCCCGCCAACATCGTCCGGGGCTCAAAGTG
TTGTTCATGACCGGGTACGCGCAGAAAGCCGCCGAACGTCAGGGCTTCCTCGAGGACGGGATGGACATGGTCGCCAAGCC
GTTTTCCATCGAACAACTGGCCGGCAAGATCCGCACGATGATCAGCCAAAACCCGTGA

Upstream 100 bases:

>100_bases
TGGACTTAAGACCGTGCGTCGTGACGCGACGGGCCTTACAGCGTCTACCGCTCTAGCATAATAGACGCCGCCTCACCGAC
CGACGCCCAGGATTGATGTG

Downstream 100 bases:

>100_bases
CTTGAGGCATAATCCGCGCCCGCCGTCACCCCGCTACAGGTATTGCACGATGAAAGCCCAAGCCCGCCACATTCTGGTGA
AAACCGCCGAAGAGGCTGAA

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 845; Mature: 845

Protein sequence:

>845_residues
MNAVPNTNDAQTLIARTDWSRSPLGAAGTWPQSLRTAVDIVLHSPMPMLLLWGPQLTQIYNDGFALLAGNKHPHAFGQPA
HQIWPELRDFTDPIYSAVLQGQVRTYSERRFTLQRDGQESDFWLDLTYSPIRDESAQVAGILVTAIETNERRRIALELQQ
RSENSLKAQRESEERLQLALAATDAVGTWDWDIGEDRFIADAHFAQLHGVDPALAGQLPISEYLHGVHPEDRAMIARSIK
HCITHGTEYAEEYRLLQANGELRWVFARGRCYKDHHGRPTRFLGAALDLTERKHTEQALRQSQTELQLIINAMPILISYV
DHEERFRLNNAAYLDWYGLTPQELYGRTIREVIGEEAYFLRAPYIAEALAGRPCSFSLYTPHRDGSQRHALMNYLPRHGA
DGAVNGFYIFVIDETERKKTEEALRNLNETLEERVSARTEQLAQANQRLQNEMFERERAEDALRHAQKMEAVGQLTGGIA
HDFNNMLTGIIGSLDLMQRYIASGRADEIGRFTDAAVSSANRAAALTHRLLAFSRRQSLDRKTIDVNELIHSLEDLIRRT
KGDPIELKLRLADNVWPVSTDVSQLENALLNLVINARDAMPDGGELLIETANVYLDGNDITTLEPVKAGDYLMLAVSDNG
TGMTPSVRSKAFDPFFTTKPIGQGTGLGLSMIYGFAQQSGGHVSLDSLPGQGTCVRLYLPRLYALEAEQPAIEAVAEAPA
VATGETVVVVEDDPAVRMLVMDLLKELGYRAHEAEDAKGALPLLESDLRVDLLVTDVGLPGMNGRQMAEIARQHRPGLKV
LFMTGYAQKAAERQGFLEDGMDMVAKPFSIEQLAGKIRTMISQNP

Sequences:

>Translated_845_residues
MNAVPNTNDAQTLIARTDWSRSPLGAAGTWPQSLRTAVDIVLHSPMPMLLLWGPQLTQIYNDGFALLAGNKHPHAFGQPA
HQIWPELRDFTDPIYSAVLQGQVRTYSERRFTLQRDGQESDFWLDLTYSPIRDESAQVAGILVTAIETNERRRIALELQQ
RSENSLKAQRESEERLQLALAATDAVGTWDWDIGEDRFIADAHFAQLHGVDPALAGQLPISEYLHGVHPEDRAMIARSIK
HCITHGTEYAEEYRLLQANGELRWVFARGRCYKDHHGRPTRFLGAALDLTERKHTEQALRQSQTELQLIINAMPILISYV
DHEERFRLNNAAYLDWYGLTPQELYGRTIREVIGEEAYFLRAPYIAEALAGRPCSFSLYTPHRDGSQRHALMNYLPRHGA
DGAVNGFYIFVIDETERKKTEEALRNLNETLEERVSARTEQLAQANQRLQNEMFERERAEDALRHAQKMEAVGQLTGGIA
HDFNNMLTGIIGSLDLMQRYIASGRADEIGRFTDAAVSSANRAAALTHRLLAFSRRQSLDRKTIDVNELIHSLEDLIRRT
KGDPIELKLRLADNVWPVSTDVSQLENALLNLVINARDAMPDGGELLIETANVYLDGNDITTLEPVKAGDYLMLAVSDNG
TGMTPSVRSKAFDPFFTTKPIGQGTGLGLSMIYGFAQQSGGHVSLDSLPGQGTCVRLYLPRLYALEAEQPAIEAVAEAPA
VATGETVVVVEDDPAVRMLVMDLLKELGYRAHEAEDAKGALPLLESDLRVDLLVTDVGLPGMNGRQMAEIARQHRPGLKV
LFMTGYAQKAAERQGFLEDGMDMVAKPFSIEQLAGKIRTMISQNP
>Mature_845_residues
MNAVPNTNDAQTLIARTDWSRSPLGAAGTWPQSLRTAVDIVLHSPMPMLLLWGPQLTQIYNDGFALLAGNKHPHAFGQPA
HQIWPELRDFTDPIYSAVLQGQVRTYSERRFTLQRDGQESDFWLDLTYSPIRDESAQVAGILVTAIETNERRRIALELQQ
RSENSLKAQRESEERLQLALAATDAVGTWDWDIGEDRFIADAHFAQLHGVDPALAGQLPISEYLHGVHPEDRAMIARSIK
HCITHGTEYAEEYRLLQANGELRWVFARGRCYKDHHGRPTRFLGAALDLTERKHTEQALRQSQTELQLIINAMPILISYV
DHEERFRLNNAAYLDWYGLTPQELYGRTIREVIGEEAYFLRAPYIAEALAGRPCSFSLYTPHRDGSQRHALMNYLPRHGA
DGAVNGFYIFVIDETERKKTEEALRNLNETLEERVSARTEQLAQANQRLQNEMFERERAEDALRHAQKMEAVGQLTGGIA
HDFNNMLTGIIGSLDLMQRYIASGRADEIGRFTDAAVSSANRAAALTHRLLAFSRRQSLDRKTIDVNELIHSLEDLIRRT
KGDPIELKLRLADNVWPVSTDVSQLENALLNLVINARDAMPDGGELLIETANVYLDGNDITTLEPVKAGDYLMLAVSDNG
TGMTPSVRSKAFDPFFTTKPIGQGTGLGLSMIYGFAQQSGGHVSLDSLPGQGTCVRLYLPRLYALEAEQPAIEAVAEAPA
VATGETVVVVEDDPAVRMLVMDLLKELGYRAHEAEDAKGALPLLESDLRVDLLVTDVGLPGMNGRQMAEIARQHRPGLKV
LFMTGYAQKAAERQGFLEDGMDMVAKPFSIEQLAGKIRTMISQNP

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=27.5303643724696, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788549, Length=252, Percent_Identity=28.1746031746032, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI87081816, Length=420, Percent_Identity=24.5238095238095, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788713, Length=270, Percent_Identity=28.8888888888889, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790300, Length=281, Percent_Identity=28.1138790035587, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI48994928, Length=405, Percent_Identity=24.4444444444444, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788381, Length=340, Percent_Identity=20.8823529411765, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI145693157, Length=138, Percent_Identity=34.0579710144928, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 94289; Mature: 94289

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVPNTNDAQTLIARTDWSRSPLGAAGTWPQSLRTAVDIVLHSPMPMLLLWGPQLTQIY
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
NDGFALLAGNKHPHAFGQPAHQIWPELRDFTDPIYSAVLQGQVRTYSERRFTLQRDGQES
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCC
DFWLDLTYSPIRDESAQVAGILVTAIETNERRRIALELQQRSENSLKAQRESEERLQLAL
CEEEEEECCCCCCCCCCEEEEEEEEEECCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHHE
AATDAVGTWDWDIGEDRFIADAHFAQLHGVDPALAGQLPISEYLHGVHPEDRAMIARSIK
EECCCCCCCCCCCCCCCEEECHHHHHHCCCCHHHCCCCCHHHHHCCCCCCHHHHHHHHHH
HCITHGTEYAEEYRLLQANGELRWVFARGRCYKDHHGRPTRFLGAALDLTERKHTEQALR
HHHHCCHHHHHHHEEEECCCCEEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
QSQTELQLIINAMPILISYVDHEERFRLNNAAYLDWYGLTPQELYGRTIREVIGEEAYFL
HHHHHHHHHHHHHHHHHHHCCCHHHEEECCCEEEEEECCCHHHHHHHHHHHHHCCCCEEE
RAPYIAEALAGRPCSFSLYTPHRDGSQRHALMNYLPRHGADGAVNGFYIFVIDETERKKT
ECCHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCHHHHH
EEALRNLNETLEERVSARTEQLAQANQRLQNEMFERERAEDALRHAQKMEAVGQLTGGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
HDFNNMLTGIIGSLDLMQRYIASGRADEIGRFTDAAVSSANRAAALTHRLLAFSRRQSLD
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
RKTIDVNELIHSLEDLIRRTKGDPIELKLRLADNVWPVSTDVSQLENALLNLVINARDAM
CCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCC
PDGGELLIETANVYLDGNDITTLEPVKAGDYLMLAVSDNGTGMTPSVRSKAFDPFFTTKP
CCCCEEEEEEEEEEECCCCCEEECCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCC
IGQGTGLGLSMIYGFAQQSGGHVSLDSLPGQGTCVRLYLPRLYALEAEQPAIEAVAEAPA
CCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECHHHEECCCCHHHHHHHHCCC
VATGETVVVVEDDPAVRMLVMDLLKELGYRAHEAEDAKGALPLLESDLRVDLLVTDVGLP
EECCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCEEEEEEEECCCC
GMNGRQMAEIARQHRPGLKVLFMTGYAQKAAERQGFLEDGMDMVAKPFSIEQLAGKIRTM
CCCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCHHHCCHHHHCCCCCHHHHHHHHHHH
ISQNP
HCCCC
>Mature Secondary Structure
MNAVPNTNDAQTLIARTDWSRSPLGAAGTWPQSLRTAVDIVLHSPMPMLLLWGPQLTQIY
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
NDGFALLAGNKHPHAFGQPAHQIWPELRDFTDPIYSAVLQGQVRTYSERRFTLQRDGQES
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCC
DFWLDLTYSPIRDESAQVAGILVTAIETNERRRIALELQQRSENSLKAQRESEERLQLAL
CEEEEEECCCCCCCCCCEEEEEEEEEECCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHHE
AATDAVGTWDWDIGEDRFIADAHFAQLHGVDPALAGQLPISEYLHGVHPEDRAMIARSIK
EECCCCCCCCCCCCCCCEEECHHHHHHCCCCHHHCCCCCHHHHHCCCCCCHHHHHHHHHH
HCITHGTEYAEEYRLLQANGELRWVFARGRCYKDHHGRPTRFLGAALDLTERKHTEQALR
HHHHCCHHHHHHHEEEECCCCEEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
QSQTELQLIINAMPILISYVDHEERFRLNNAAYLDWYGLTPQELYGRTIREVIGEEAYFL
HHHHHHHHHHHHHHHHHHHCCCHHHEEECCCEEEEEECCCHHHHHHHHHHHHHCCCCEEE
RAPYIAEALAGRPCSFSLYTPHRDGSQRHALMNYLPRHGADGAVNGFYIFVIDETERKKT
ECCHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCHHHHH
EEALRNLNETLEERVSARTEQLAQANQRLQNEMFERERAEDALRHAQKMEAVGQLTGGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
HDFNNMLTGIIGSLDLMQRYIASGRADEIGRFTDAAVSSANRAAALTHRLLAFSRRQSLD
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
RKTIDVNELIHSLEDLIRRTKGDPIELKLRLADNVWPVSTDVSQLENALLNLVINARDAM
CCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCC
PDGGELLIETANVYLDGNDITTLEPVKAGDYLMLAVSDNGTGMTPSVRSKAFDPFFTTKP
CCCCEEEEEEEEEEECCCCCEEECCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCC
IGQGTGLGLSMIYGFAQQSGGHVSLDSLPGQGTCVRLYLPRLYALEAEQPAIEAVAEAPA
CCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECHHHEECCCCHHHHHHHHCCC
VATGETVVVVEDDPAVRMLVMDLLKELGYRAHEAEDAKGALPLLESDLRVDLLVTDVGLP
EECCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCEEEEEEEECCCC
GMNGRQMAEIARQHRPGLKVLFMTGYAQKAAERQGFLEDGMDMVAKPFSIEQLAGKIRTM
CCCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCHHHCCHHHHCCCCCHHHHHHHHHHH
ISQNP
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA