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The map label for this gene is pgsA [H]

Identifier: 77459287

GI number: 77459287

Start: 3506990

End: 3507550

Strand: Reverse

Name: pgsA [H]

Synonym: Pfl01_3065

Alternate gene names: 77459287

Gene position: 3507550-3506990 (Counterclockwise)

Preceding gene: 77459288

Following gene: 77459286

Centisome position: 54.48

GC content: 54.37

Gene sequence:

>561_bases
ATGAATATCCCTAATCTGATTACCGTTCTCCGCGTCCTGCTCATCCCGATCTTCATTCTGTTGTTCTATCTGCCTTACCA
ATGGAGCTATCTGGCCTCAAGTTCGGTATTCGCCTTTGCGGCGGCAACGGACTGGCTTGACGGCTATCTTGCGCGACGTC
TGGAGCAAAGCACGCCGTTTGGTGCGTTTCTGGATCCCGTCGCTGACAAACTGATGGTGGCTGTTGCCCTGGTGTTGCTG
GTGCAAGAACATGGCAACCTTTGGCTCACACTGCCGGCCGCTGTCATCATCGGTCGCGAGATTGTTGTCTCGGCGCTGCG
TGAGTGGATGGCCGAACTCGGTGCACGGGCCCATGTGGCCGTGTCGAATCTGGGCAAGTGGAAAACTGCTGCGCAAATGC
TTGCACTGGTGATCCTCCTGGCCAATCCCAAGGTTTTCAGTTTCTGGGTTGTCATCGGTTACGCGTTACTGATGGTGTCT
GCAGGCCTGACCTTGTGGTCGATGGTTCAATACCTTCGGGCTGCCTGGCCACATCTGAAGACTGATGTTGAAAAGAAATA
A

Upstream 100 bases:

>100_bases
TCGCCAAAGCACCGGGGATCAGCAAAAAGCTAGCAGAGTCGATTTATGCAAACCTGCATAGTGAGTAGAATGCCCATTCA
CCTCGTAGCCAGTTGTGCCG

Downstream 100 bases:

>100_bases
AACTTTTTTGAATCAAAGGGTTGACGGGGCATCTGGAATCTATAGAATGCGCCACACCAAGCGGGAATAGCTCAGTTGGT
AGAGCACGACCTTGCCAAGG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MNIPNLITVLRVLLIPIFILLFYLPYQWSYLASSSVFAFAAATDWLDGYLARRLEQSTPFGAFLDPVADKLMVAVALVLL
VQEHGNLWLTLPAAVIIGREIVVSALREWMAELGARAHVAVSNLGKWKTAAQMLALVILLANPKVFSFWVVIGYALLMVS
AGLTLWSMVQYLRAAWPHLKTDVEKK

Sequences:

>Translated_186_residues
MNIPNLITVLRVLLIPIFILLFYLPYQWSYLASSSVFAFAAATDWLDGYLARRLEQSTPFGAFLDPVADKLMVAVALVLL
VQEHGNLWLTLPAAVIIGREIVVSALREWMAELGARAHVAVSNLGKWKTAAQMLALVILLANPKVFSFWVVIGYALLMVS
AGLTLWSMVQYLRAAWPHLKTDVEKK
>Mature_186_residues
MNIPNLITVLRVLLIPIFILLFYLPYQWSYLASSSVFAFAAATDWLDGYLARRLEQSTPFGAFLDPVADKLMVAVALVLL
VQEHGNLWLTLPAAVIIGREIVVSALREWMAELGARAHVAVSNLGKWKTAAQMLALVILLANPKVFSFWVVIGYALLMVS
AGLTLWSMVQYLRAAWPHLKTDVEKK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=175, Percent_Identity=60.5714285714286, Blast_Score=202, Evalue=9e-54,
Organism=Saccharomyces cerevisiae, GI6320059, Length=157, Percent_Identity=33.7579617834395, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20739; Mature: 20739

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPNLITVLRVLLIPIFILLFYLPYQWSYLASSSVFAFAAATDWLDGYLARRLEQSTPF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCC
GAFLDPVADKLMVAVALVLLVQEHGNLWLTLPAAVIIGREIVVSALREWMAELGARAHVA
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VSNLGKWKTAAQMLALVILLANPKVFSFWVVIGYALLMVSAGLTLWSMVQYLRAAWPHLK
HHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHH
TDVEKK
CCCCCC
>Mature Secondary Structure
MNIPNLITVLRVLLIPIFILLFYLPYQWSYLASSSVFAFAAATDWLDGYLARRLEQSTPF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCC
GAFLDPVADKLMVAVALVLLVQEHGNLWLTLPAAVIIGREIVVSALREWMAELGARAHVA
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VSNLGKWKTAAQMLALVILLANPKVFSFWVVIGYALLMVSAGLTLWSMVQYLRAAWPHLK
HHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHH
TDVEKK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075420 [H]