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The map label for this gene is acoR [H]

Identifier: 77459201

GI number: 77459201

Start: 3415294

End: 3417174

Strand: Reverse

Name: acoR [H]

Synonym: Pfl01_2976

Alternate gene names: 77459201

Gene position: 3417174-3415294 (Counterclockwise)

Preceding gene: 77459202

Following gene: 77459200

Centisome position: 53.07

GC content: 52.37

Gene sequence:

>1881_bases
ATGCTATGTAATCATATGCGGCTGGTCATTATTAATGATAAAAACATACAAGAATGTGGAAAGGTAATGAGTGGTCAGCA
AATGAATATAAGAGACATGCATGGCCTTGATGAGGTTCGGCGTCGCTTTCTGGATGGGCACTCTTTGCCGGCGGATCTGC
TGCCTACTGCAGTAGCCAATTCTTGGGAGCGGTCCAGGAAAGCAGGGCTCTCACCTTGGGATAAGCGACTGACTGGACGT
TGGCGCACCCATGAATTAAGTAGTTCGGATTCGCGTTTGGCTGCATGCGCTCAACCTGAGCTCGACAGGCTGTGGGGAAT
ATTCGGAGGGCAAGACTGGGCCCTGTTTTGCGTCAACCTCGAAGGCGTGATCGTTTATGCCAAGCACGCGTCCCAGCCCG
ACCTTGTGGACCCACTGAAAGTGGGAAAGCGCGTCAATGAAGTGGATATCGGAACCACTGCGCCCAGTTGCACACTCCAT
GAGCAGCAGCCGTTTATCGTCTGCGGCGGTATGCATTACTTAAAAGAATTTGAAAATTTTTTCTGCGTATCCGTTCCTGT
TTTCGGTGTGCGTGGGGAGTTGGTGGGTGCAATCGACATAACCGGTATCGGCCAGCGCAATGCGACTGCTGTTCTGGAGC
AGCTAAAGATCGCGTCCATGGCCATCGAAAGCAGGTTGTATTCGGGGTTGGTGGATTGCCAGATCGTAGCACTTCAGTTT
GACGCGAGATTGATCGGAACACCTTTCCAGGGATTGGTCGCTTTCGATCAGAATGGAAGGTTCTGTGCCGCCAATAAAGT
AGCGAAGAAGATATTGGGCATCGATGCTTCTTCGCCAGTCGAGTCCTCATTGGACTGGGATAGTTTTTTTGAGCGTGGGC
CACAGTCCATAGTCGTGAACTCACCCAGTCTGATAGCGCTGAACGACGGGTCTTCGGTTTATGCCCAGTCGTTATCGTTG
CCTGGCGGCGCTCAGCCTGCTGCTCGTTTGTGTCATACATCCCCTGGGGTCGGACACGATCCTGCGCTCAATCAGCAATT
CAACATGGCCTCGAAAGCCTTCGCAGCTAGCATTCCCATCATCTTGCAAGGCGAAACGGGTACGGGAAAAGAGGTATTCG
CCAGGGCACTTCACGACTCGTTGAATCCTGGCGCTCCGTTCATAGCCATTAACTGTTCTGCCATACCTGAGAATTTGATT
GAATCGGAGTTGTTTGGCTACGTTGAAGGAACATTTACAGGGGCACGTCGAGGCGGTGCGAAAGGTCGTATCGAAGAAGC
GCATGGCGGGACATTATTGCTCGATGAGATTGGCGATATGCCGTTCAACCTTCAGACCAGGCTGCTTCGGGTACTGCAAG
AGAGGGAAGTGACCCGTCTTGGCAGCTCAGAACGACATCCAGTCAATATTAGGGTTATCAGCGCGACCCATTGCGATATC
CATAAGCTTATTGAGGAGCATCGTTTCAGAGAGGATCTTTTTTATCGCCTCAATGGCATGCAGGTTGGTATTCCGGCGCT
CCGTCAGCGGCAGGATATGGAAGATATCATCACCAAATTGACCCAGCGCTATCAGGGAGGCGCGATTCATCCCGCCGCGT
TGGAGCTGCTGAAGAACCAGGAGTGGCGCGGAAATATCAGGCAACTGGAGCAGGTGATCCGGCTGGCTGTGGCTTTGGCT
GGCGCAGGGCTCGTGATCCTGCCGGAACACTTTCCAGGGTTGGAGCAGCCTGAAGAGAAGCGTGATGAGAAATCGTTAAA
GGAATTTGAAAGGAAGAAGATTCAAGACGCGCTGGATGCTAATCGCGGCAACGTGAAAGCGACTGCGCAGCAGCTCGGCG
TTGCGCGTGGCACTATCTATCGTAAGCTGAGAATGGAATAG

Upstream 100 bases:

>100_bases
ATCAAGGATGAGGCCACGCCTTATGCCCTGTAAGGCACTGCATCGAACATAACTGCAAGATCTTGAAGAAAAAGCGCCCG
TTCTGAACGGGCGCTTTTTT

Downstream 100 bases:

>100_bases
ATTGTTATGCCATTCGGATTGAAGGGGGGTGGTAATGCCTGGCCCCCTCTTGGTGTGACGGTATTGGTTGCATTCATCAG
TGTTTGTATCCGAACGGCGC

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MLCNHMRLVIINDKNIQECGKVMSGQQMNIRDMHGLDEVRRRFLDGHSLPADLLPTAVANSWERSRKAGLSPWDKRLTGR
WRTHELSSSDSRLAACAQPELDRLWGIFGGQDWALFCVNLEGVIVYAKHASQPDLVDPLKVGKRVNEVDIGTTAPSCTLH
EQQPFIVCGGMHYLKEFENFFCVSVPVFGVRGELVGAIDITGIGQRNATAVLEQLKIASMAIESRLYSGLVDCQIVALQF
DARLIGTPFQGLVAFDQNGRFCAANKVAKKILGIDASSPVESSLDWDSFFERGPQSIVVNSPSLIALNDGSSVYAQSLSL
PGGAQPAARLCHTSPGVGHDPALNQQFNMASKAFAASIPIILQGETGTGKEVFARALHDSLNPGAPFIAINCSAIPENLI
ESELFGYVEGTFTGARRGGAKGRIEEAHGGTLLLDEIGDMPFNLQTRLLRVLQEREVTRLGSSERHPVNIRVISATHCDI
HKLIEEHRFREDLFYRLNGMQVGIPALRQRQDMEDIITKLTQRYQGGAIHPAALELLKNQEWRGNIRQLEQVIRLAVALA
GAGLVILPEHFPGLEQPEEKRDEKSLKEFERKKIQDALDANRGNVKATAQQLGVARGTIYRKLRME

Sequences:

>Translated_626_residues
MLCNHMRLVIINDKNIQECGKVMSGQQMNIRDMHGLDEVRRRFLDGHSLPADLLPTAVANSWERSRKAGLSPWDKRLTGR
WRTHELSSSDSRLAACAQPELDRLWGIFGGQDWALFCVNLEGVIVYAKHASQPDLVDPLKVGKRVNEVDIGTTAPSCTLH
EQQPFIVCGGMHYLKEFENFFCVSVPVFGVRGELVGAIDITGIGQRNATAVLEQLKIASMAIESRLYSGLVDCQIVALQF
DARLIGTPFQGLVAFDQNGRFCAANKVAKKILGIDASSPVESSLDWDSFFERGPQSIVVNSPSLIALNDGSSVYAQSLSL
PGGAQPAARLCHTSPGVGHDPALNQQFNMASKAFAASIPIILQGETGTGKEVFARALHDSLNPGAPFIAINCSAIPENLI
ESELFGYVEGTFTGARRGGAKGRIEEAHGGTLLLDEIGDMPFNLQTRLLRVLQEREVTRLGSSERHPVNIRVISATHCDI
HKLIEEHRFREDLFYRLNGMQVGIPALRQRQDMEDIITKLTQRYQGGAIHPAALELLKNQEWRGNIRQLEQVIRLAVALA
GAGLVILPEHFPGLEQPEEKRDEKSLKEFERKKIQDALDANRGNVKATAQQLGVARGTIYRKLRME
>Mature_626_residues
MLCNHMRLVIINDKNIQECGKVMSGQQMNIRDMHGLDEVRRRFLDGHSLPADLLPTAVANSWERSRKAGLSPWDKRLTGR
WRTHELSSSDSRLAACAQPELDRLWGIFGGQDWALFCVNLEGVIVYAKHASQPDLVDPLKVGKRVNEVDIGTTAPSCTLH
EQQPFIVCGGMHYLKEFENFFCVSVPVFGVRGELVGAIDITGIGQRNATAVLEQLKIASMAIESRLYSGLVDCQIVALQF
DARLIGTPFQGLVAFDQNGRFCAANKVAKKILGIDASSPVESSLDWDSFFERGPQSIVVNSPSLIALNDGSSVYAQSLSL
PGGAQPAARLCHTSPGVGHDPALNQQFNMASKAFAASIPIILQGETGTGKEVFARALHDSLNPGAPFIAINCSAIPENLI
ESELFGYVEGTFTGARRGGAKGRIEEAHGGTLLLDEIGDMPFNLQTRLLRVLQEREVTRLGSSERHPVNIRVISATHCDI
HKLIEEHRFREDLFYRLNGMQVGIPALRQRQDMEDIITKLTQRYQGGAIHPAALELLKNQEWRGNIRQLEQVIRLAVALA
GAGLVILPEHFPGLEQPEEKRDEKSLKEFERKKIQDALDANRGNVKATAQQLGVARGTIYRKLRME

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=432, Percent_Identity=34.7222222222222, Blast_Score=212, Evalue=6e-56,
Organism=Escherichia coli, GI1786524, Length=312, Percent_Identity=41.025641025641, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1788550, Length=308, Percent_Identity=37.987012987013, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI1790437, Length=301, Percent_Identity=39.5348837209302, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1790299, Length=333, Percent_Identity=37.8378378378378, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI87082117, Length=309, Percent_Identity=40.7766990291262, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1788905, Length=299, Percent_Identity=39.7993311036789, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI87082152, Length=329, Percent_Identity=34.9544072948328, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1789087, Length=306, Percent_Identity=36.6013071895425, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1787583, Length=305, Percent_Identity=36.0655737704918, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI87081872, Length=283, Percent_Identity=36.0424028268551, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081858, Length=617, Percent_Identity=24.1491085899514, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1789828, Length=294, Percent_Identity=28.9115646258503, Blast_Score=116, Evalue=5e-27,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 69070; Mature: 69070

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4 ; PS00134 TRYPSIN_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCNHMRLVIINDKNIQECGKVMSGQQMNIRDMHGLDEVRRRFLDGHSLPADLLPTAVAN
CCCCCEEEEEECCCCHHHHHHHHCCCCCCHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHH
SWERSRKAGLSPWDKRLTGRWRTHELSSSDSRLAACAQPELDRLWGIFGGQDWALFCVNL
HHHHHHHCCCCHHHHHHCCCCEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEE
EGVIVYAKHASQPDLVDPLKVGKRVNEVDIGTTAPSCTLHEQQPFIVCGGMHYLKEFENF
CEEEEEEECCCCCCCCCHHHHCCCCCEEECCCCCCCCEEECCCCEEEECCHHHHHHHCCE
FCVSVPVFGVRGELVGAIDITGIGQRNATAVLEQLKIASMAIESRLYSGLVDCQIVALQF
EEEEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
DARLIGTPFQGLVAFDQNGRFCAANKVAKKILGIDASSPVESSLDWDSFFERGPQSIVVN
CCEEECCCCCCEEEECCCCCEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEC
SPSLIALNDGSSVYAQSLSLPGGAQPAARLCHTSPGVGHDPALNQQFNMASKAFAASIPI
CCCEEEECCCCHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCE
ILQGETGTGKEVFARALHDSLNPGAPFIAINCSAIPENLIESELFGYVEGTFTGARRGGA
EEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCC
KGRIEEAHGGTLLLDEIGDMPFNLQTRLLRVLQEREVTRLGSSERHPVNIRVISATHCDI
CCCEECCCCCEEEEHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHH
HKLIEEHRFREDLFYRLNGMQVGIPALRQRQDMEDIITKLTQRYQGGAIHPAALELLKNQ
HHHHHHHHHHHHHHHHHCCEEECCHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHCC
EWRGNIRQLEQVIRLAVALAGAGLVILPEHFPGLEQPEEKRDEKSLKEFERKKIQDALDA
CCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
NRGNVKATAQQLGVARGTIYRKLRME
CCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLCNHMRLVIINDKNIQECGKVMSGQQMNIRDMHGLDEVRRRFLDGHSLPADLLPTAVAN
CCCCCEEEEEECCCCHHHHHHHHCCCCCCHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHH
SWERSRKAGLSPWDKRLTGRWRTHELSSSDSRLAACAQPELDRLWGIFGGQDWALFCVNL
HHHHHHHCCCCHHHHHHCCCCEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEE
EGVIVYAKHASQPDLVDPLKVGKRVNEVDIGTTAPSCTLHEQQPFIVCGGMHYLKEFENF
CEEEEEEECCCCCCCCCHHHHCCCCCEEECCCCCCCCEEECCCCEEEECCHHHHHHHCCE
FCVSVPVFGVRGELVGAIDITGIGQRNATAVLEQLKIASMAIESRLYSGLVDCQIVALQF
EEEEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
DARLIGTPFQGLVAFDQNGRFCAANKVAKKILGIDASSPVESSLDWDSFFERGPQSIVVN
CCEEECCCCCCEEEECCCCCEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEC
SPSLIALNDGSSVYAQSLSLPGGAQPAARLCHTSPGVGHDPALNQQFNMASKAFAASIPI
CCCEEEECCCCHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCE
ILQGETGTGKEVFARALHDSLNPGAPFIAINCSAIPENLIESELFGYVEGTFTGARRGGA
EEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCC
KGRIEEAHGGTLLLDEIGDMPFNLQTRLLRVLQEREVTRLGSSERHPVNIRVISATHCDI
CCCEECCCCCEEEEHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHH
HKLIEEHRFREDLFYRLNGMQVGIPALRQRQDMEDIITKLTQRYQGGAIHPAALELLKNQ
HHHHHHHHHHHHHHHHHCCEEECCHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHCC
EWRGNIRQLEQVIRLAVALAGAGLVILPEHFPGLEQPEEKRDEKSLKEFERKKIQDALDA
CCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
NRGNVKATAQQLGVARGTIYRKLRME
CCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]