Click here to switch to the map view.

The map label for this gene is ttuB [H]

Identifier: 77459135

GI number: 77459135

Start: 3355567

End: 3356877

Strand: Direct

Name: ttuB [H]

Synonym: Pfl01_2910

Alternate gene names: 77459135

Gene position: 3355567-3356877 (Clockwise)

Preceding gene: 77459131

Following gene: 77459139

Centisome position: 52.12

GC content: 61.17

Gene sequence:

>1311_bases
ATGTCGCAGAGCGCCGCTGCCGCCCAGACCATCGTTGACGATAAAAATGCCGTCTACAAACGCATCACCCTGCGTTTGAT
CCCCTTCATCTTCATCTGCTACCTGTTCAACTACCTCGACCGGGTCAACGTTGGATTCGCCAAACTGCAGATGCTCGACG
CGCTGAAATTCAGCGAAACCGTGTACGGCCTCGGTGCCGGGATCTTCTTCATCGGCTACGTGCTGTGCGGCGTACCGAGC
AACCTGGCGCTGACCAAATTCGGCCCACGGCGCTGGATTGCGCTGATGATGATCACCTGGGGCACACTGTCTACCTGCCT
GCTGTTCGTCACCACGCCGACCGAGTTCTACACCCTGCGCCTGTTCACCGGCGCCGCCGAAGCCGGATTCTTCCCAGGTG
TTGTGCTGTATCTCTCGCAGTGGTTCCCGACCTTCCGCCGTGGCCGGATCATGGCGTTGTTCATGTCGGCGATTCCGGTG
TCGGGCCTGCTCGGCAGCCCGTTTTCCGGCTGGATCCTCAATCACCTCGCCGCCGGCCAGGGTGGTCTGGCCGGTTGGCA
GTGGATGTTCCTGCTGCAAGGCATTCCAACCGTGGTGCTGGGCGCACTCGCCTACTTCCTGTTGAGCGACAACTTCGCCG
CTGCCAAATGGCTGACCCCGCACGAGCGTTCGGTGCTGGAAGCCGATCAGGCAGAGGACCTGGCGAACAAACCGAAAACC
ACTTCCGATTCGCTGATTGCCGTATTCAAGAACCCGGCCATCTGGGCCTTCGGCCTGATCTACTTCTGCATCCAGAGCGG
CGTGTACGCGATCAACTTCTGGCTGCCGTCGATCATCAAGAACCTCGGCTTCAGCGACAACCTGGTGATTGGCTGGTTGA
GTGCGATTCCGTATCTGCTGGCGGCGGTGTTCATGCTGGTAGTTGGTCGCTCGGCGGACTTGCGCAAAGAGCGTCGCTGG
CATCTGGTGGTGCCAATGTTGATGGGCGCTGTCGGCCTGCTGATCGCGGTGAACTTCGCAGCGAATCCCGCGATTGCGAT
CCTCGGCCTGACCATCGCGACCATGGGCGCGTTGACCGGTCTGCCGATGTTCTGGCCGGTGCCGACTGCCATGCTCAGTG
CAGGTGCTGCGGCGGGCGGGTTGGCGTTGATCAACTCGATGGGGCAGATGGCCGGGTTCCTCAGCCCTTACCTTGTGGGT
TGGGTGAAGGACAGCACCGGGTCGACCGACGCGGCGTTGTATCTGCTGGCGGGTGTGATTGTTGGCGGGAGTCTGCTGGC
GTTGCGGATGACGCGGACGTTGCGGGCTTAA

Upstream 100 bases:

>100_bases
CTCAGGCACAAAGACAATCCGGCCAAAGGTGGCCGAGACTCTCAGGGCGATCAACGTTACCCTTTGCATCGCAAAAAATC
ATAATAAAGAGAGAGCCGCC

Downstream 100 bases:

>100_bases
GCCTTAGTCGAAATACAGAAACGGCCCTTTTCGGGCCGTTTTTCTTTTGGATCTAGCTACAGCGGTGCTTCAGTCTTGAG
TTCCAGATTATCCAGCGCCC

Product: general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSQSAAAAQTIVDDKNAVYKRITLRLIPFIFICYLFNYLDRVNVGFAKLQMLDALKFSETVYGLGAGIFFIGYVLCGVPS
NLALTKFGPRRWIALMMITWGTLSTCLLFVTTPTEFYTLRLFTGAAEAGFFPGVVLYLSQWFPTFRRGRIMALFMSAIPV
SGLLGSPFSGWILNHLAAGQGGLAGWQWMFLLQGIPTVVLGALAYFLLSDNFAAAKWLTPHERSVLEADQAEDLANKPKT
TSDSLIAVFKNPAIWAFGLIYFCIQSGVYAINFWLPSIIKNLGFSDNLVIGWLSAIPYLLAAVFMLVVGRSADLRKERRW
HLVVPMLMGAVGLLIAVNFAANPAIAILGLTIATMGALTGLPMFWPVPTAMLSAGAAAGGLALINSMGQMAGFLSPYLVG
WVKDSTGSTDAALYLLAGVIVGGSLLALRMTRTLRA

Sequences:

>Translated_436_residues
MSQSAAAAQTIVDDKNAVYKRITLRLIPFIFICYLFNYLDRVNVGFAKLQMLDALKFSETVYGLGAGIFFIGYVLCGVPS
NLALTKFGPRRWIALMMITWGTLSTCLLFVTTPTEFYTLRLFTGAAEAGFFPGVVLYLSQWFPTFRRGRIMALFMSAIPV
SGLLGSPFSGWILNHLAAGQGGLAGWQWMFLLQGIPTVVLGALAYFLLSDNFAAAKWLTPHERSVLEADQAEDLANKPKT
TSDSLIAVFKNPAIWAFGLIYFCIQSGVYAINFWLPSIIKNLGFSDNLVIGWLSAIPYLLAAVFMLVVGRSADLRKERRW
HLVVPMLMGAVGLLIAVNFAANPAIAILGLTIATMGALTGLPMFWPVPTAMLSAGAAAGGLALINSMGQMAGFLSPYLVG
WVKDSTGSTDAALYLLAGVIVGGSLLALRMTRTLRA
>Mature_435_residues
SQSAAAAQTIVDDKNAVYKRITLRLIPFIFICYLFNYLDRVNVGFAKLQMLDALKFSETVYGLGAGIFFIGYVLCGVPSN
LALTKFGPRRWIALMMITWGTLSTCLLFVTTPTEFYTLRLFTGAAEAGFFPGVVLYLSQWFPTFRRGRIMALFMSAIPVS
GLLGSPFSGWILNHLAAGQGGLAGWQWMFLLQGIPTVVLGALAYFLLSDNFAAAKWLTPHERSVLEADQAEDLANKPKTT
SDSLIAVFKNPAIWAFGLIYFCIQSGVYAINFWLPSIIKNLGFSDNLVIGWLSAIPYLLAAVFMLVVGRSADLRKERRWH
LVVPMLMGAVGLLIAVNFAANPAIAILGLTIATMGALTGLPMFWPVPTAMLSAGAAAGGLALINSMGQMAGFLSPYLVGW
VKDSTGSTDAALYLLAGVIVGGSLLALRMTRTLRA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=304, Percent_Identity=23.6842105263158, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87082071, Length=427, Percent_Identity=36.768149882904, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI2367379, Length=431, Percent_Identity=24.8259860788863, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789515, Length=442, Percent_Identity=25.1131221719457, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1789152, Length=445, Percent_Identity=22.6966292134831, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082320, Length=418, Percent_Identity=22.2488038277512, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319876, Length=375, Percent_Identity=26.6666666666667, Blast_Score=93, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6322025, Length=293, Percent_Identity=23.8907849829352, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6321698, Length=346, Percent_Identity=23.121387283237, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324410, Length=148, Percent_Identity=28.3783783783784, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584153, Length=361, Percent_Identity=22.9916897506925, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI20130167, Length=426, Percent_Identity=22.5352112676056, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24583789, Length=368, Percent_Identity=23.9130434782609, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24653727, Length=407, Percent_Identity=22.8501228501229, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47219; Mature: 47087

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSAAAAQTIVDDKNAVYKRITLRLIPFIFICYLFNYLDRVNVGFAKLQMLDALKFSET
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VYGLGAGIFFIGYVLCGVPSNLALTKFGPRRWIALMMITWGTLSTCLLFVTTPTEFYTLR
HHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEE
LFTGAAEAGFFPGVVLYLSQWFPTFRRGRIMALFMSAIPVSGLLGSPFSGWILNHLAAGQ
EEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCC
GGLAGWQWMFLLQGIPTVVLGALAYFLLSDNFAAAKWLTPHERSVLEADQAEDLANKPKT
CCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
TSDSLIAVFKNPAIWAFGLIYFCIQSGVYAINFWLPSIIKNLGFSDNLVIGWLSAIPYLL
CCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AAVFMLVVGRSADLRKERRWHLVVPMLMGAVGLLIAVNFAANPAIAILGLTIATMGALTG
HHHHHHHHCCCCHHHHHCCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
LPMFWPVPTAMLSAGAAAGGLALINSMGQMAGFLSPYLVGWVKDSTGSTDAALYLLAGVI
CCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHH
VGGSLLALRMTRTLRA
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQSAAAAQTIVDDKNAVYKRITLRLIPFIFICYLFNYLDRVNVGFAKLQMLDALKFSET
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VYGLGAGIFFIGYVLCGVPSNLALTKFGPRRWIALMMITWGTLSTCLLFVTTPTEFYTLR
HHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEE
LFTGAAEAGFFPGVVLYLSQWFPTFRRGRIMALFMSAIPVSGLLGSPFSGWILNHLAAGQ
EEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCC
GGLAGWQWMFLLQGIPTVVLGALAYFLLSDNFAAAKWLTPHERSVLEADQAEDLANKPKT
CCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
TSDSLIAVFKNPAIWAFGLIYFCIQSGVYAINFWLPSIIKNLGFSDNLVIGWLSAIPYLL
CCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AAVFMLVVGRSADLRKERRWHLVVPMLMGAVGLLIAVNFAANPAIAILGLTIATMGALTG
HHHHHHHHCCCCHHHHHCCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
LPMFWPVPTAMLSAGAAAGGLALINSMGQMAGFLSPYLVGWVKDSTGSTDAALYLLAGVI
CCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHH
VGGSLLALRMTRTLRA
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]