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The map label for this gene is phoP [H]

Identifier: 77459117

GI number: 77459117

Start: 3331953

End: 3332654

Strand: Reverse

Name: phoP [H]

Synonym: Pfl01_2892

Alternate gene names: 77459117

Gene position: 3332654-3331953 (Counterclockwise)

Preceding gene: 77459122

Following gene: 77459116

Centisome position: 51.76

GC content: 63.53

Gene sequence:

>702_bases
ATGCCCAACATTCTTCTGGTCGAAGACGACACCGCCCTCGCCGAACTGATTTCCAGCTATCTGGAGCGCAACGGTTACTC
CGTCAGCGTGATCGGCCGTGGCGACCATGTGCGCGAACGGGCGCGGCTCAATCCGCCGGATCTGGTGATTCTCGACCTGA
TGCTGCCGGGCCTCGACGGCTTGCAGGTTTGCAGATTGCTGCGTGCCGATTCGGCAACGCTGCCGATCCTGATGCTCACC
GCCCGTGACGACAGCCACGATCAGGTACTGGGCCTGGAAATGGGCGCCGACGATTACGTCACCAAACCCTGCGAGCCACG
GGTCCTGCTGGCGCGGGTACGCACCTTGCTGCGGCGCAGCAGCCTCGGCGAGCCGATGACCGCCAACGACCGGATCCTGA
TGGGCAACCTGTGCATCGACCTGTCGGAGCGCACGGTGACCTGGCGCGAACAACCGGTGGAACTGTCCAGCGGCGAATAC
AACCTGCTGGTGGTGCTGGCCCGTCATGCCGGTGAAGTGCTGAGCCGCGACCAGATCCTGCAACGCCTGCGCGGTATCGA
GTTCAACGGCACTGACCGTTCGGTGGACGTGGCGATTTCCAAGCTGCGACGCAAGTTCGACGACCACGCCGGCGAGGCGC
GCAAGATCAAGACCGTGTGGGGCAAGGGGTATCTGTTCAGCCGTTCCGAGTGGGAATGCTGA

Upstream 100 bases:

>100_bases
TGTAAGGGTTTTGCTCAGGGACGGGCGAGGGCGTATATCCTTCAGGCCTTGAAATTTTTTGCGACATAGCAGTCGCCACC
GCCTGTTCTGGATCACCTCA

Downstream 100 bases:

>100_bases
TTCGATGTTCAGAATCCTGTTTCGCCTCTATCTGGTGACGATCGTCTCCTACAGTGCGGCGATCTATCTGGTGCCGGATC
TGGTGGTGATGGTGTTCAAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MPNILLVEDDTALAELISSYLERNGYSVSVIGRGDHVRERARLNPPDLVILDLMLPGLDGLQVCRLLRADSATLPILMLT
ARDDSHDQVLGLEMGADDYVTKPCEPRVLLARVRTLLRRSSLGEPMTANDRILMGNLCIDLSERTVTWREQPVELSSGEY
NLLVVLARHAGEVLSRDQILQRLRGIEFNGTDRSVDVAISKLRRKFDDHAGEARKIKTVWGKGYLFSRSEWEC

Sequences:

>Translated_233_residues
MPNILLVEDDTALAELISSYLERNGYSVSVIGRGDHVRERARLNPPDLVILDLMLPGLDGLQVCRLLRADSATLPILMLT
ARDDSHDQVLGLEMGADDYVTKPCEPRVLLARVRTLLRRSSLGEPMTANDRILMGNLCIDLSERTVTWREQPVELSSGEY
NLLVVLARHAGEVLSRDQILQRLRGIEFNGTDRSVDVAISKLRRKFDDHAGEARKIKTVWGKGYLFSRSEWEC
>Mature_232_residues
PNILLVEDDTALAELISSYLERNGYSVSVIGRGDHVRERARLNPPDLVILDLMLPGLDGLQVCRLLRADSATLPILMLTA
RDDSHDQVLGLEMGADDYVTKPCEPRVLLARVRTLLRRSSLGEPMTANDRILMGNLCIDLSERTVTWREQPVELSSGEYN
LLVVLARHAGEVLSRDQILQRLRGIEFNGTDRSVDVAISKLRRKFDDHAGEARKIKTVWGKGYLFSRSEWEC

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=40.9691629955947, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI145693140, Length=240, Percent_Identity=43.3333333333333, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=41.7040358744395, Blast_Score=167, Evalue=4e-43,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=38.9380530973451, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=38.2882882882883, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=37.5, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=37.9464285714286, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=38.2608695652174, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=37.5, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=37.5565610859729, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=32.6086956521739, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=34.7826086956522, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=33.1838565022422, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=33.920704845815, Blast_Score=110, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26238; Mature: 26106

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNILLVEDDTALAELISSYLERNGYSVSVIGRGDHVRERARLNPPDLVILDLMLPGLDG
CCCEEEEECCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCCCCEEEEEECCCCCCH
LQVCRLLRADSATLPILMLTARDDSHDQVLGLEMGADDYVTKPCEPRVLLARVRTLLRRS
HHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
SLGEPMTANDRILMGNLCIDLSERTVTWREQPVELSSGEYNLLVVLARHAGEVLSRDQIL
CCCCCCCCCCEEEEEEEEEECCCCEEEECCCCEECCCCCEEEEEEEEHHHHHHHHHHHHH
QRLRGIEFNGTDRSVDVAISKLRRKFDDHAGEARKIKTVWGKGYLFSRSEWEC
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEECCCCCCC
>Mature Secondary Structure 
PNILLVEDDTALAELISSYLERNGYSVSVIGRGDHVRERARLNPPDLVILDLMLPGLDG
CCEEEEECCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCCCCEEEEEECCCCCCH
LQVCRLLRADSATLPILMLTARDDSHDQVLGLEMGADDYVTKPCEPRVLLARVRTLLRRS
HHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
SLGEPMTANDRILMGNLCIDLSERTVTWREQPVELSSGEYNLLVVLARHAGEVLSRDQIL
CCCCCCCCCCEEEEEEEEEECCCCEEEECCCCEECCCCCEEEEEEEEHHHHHHHHHHHHH
QRLRGIEFNGTDRSVDVAISKLRRKFDDHAGEARKIKTVWGKGYLFSRSEWEC
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]