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The map label for this gene is udg [H]

Identifier: 77459073

GI number: 77459073

Start: 3285317

End: 3286696

Strand: Direct

Name: udg [H]

Synonym: Pfl01_2848

Alternate gene names: 77459073

Gene position: 3285317-3286696 (Clockwise)

Preceding gene: 77459072

Following gene: 77459074

Centisome position: 51.03

GC content: 61.74

Gene sequence:

>1380_bases
ATGAAAATCACAGTATTTGGTAGCGGTTATGTCGGTCTGGTGCAGGCTGCCGTCCTGGCCGAGGTGGGTCACGACGTGGT
GTGCATGGACATCGACGAGAAGAAAATCGAACTGTTGCGCCAGGGCCACGTCAGCATCTTCGAGCCGGGGCTGGCCAGTC
TGGTCCGCGAAGGCCTGGATGCCGGGCGCCTGCAATTCACCTGCGATGAAATACTTGCGGTGCAACATGGCAAGGTTGCG
TTCATTGCCGTTGGCACCCCGTCCAACGAGGACGGTTCGGCCGACCTGCGTTATGTGCTGTCGGTGGGCGATGCCGTGGC
CCGGCACCGTGAGAAACCGCTGATCCTGGTGGAGAAATCCACCGTACCGGTCGGCACCGGTGACACTTTGCGTGCGCATC
TGGATAAAGCCTTGGTCAAGGCCGGACGTCTGTTGCAGTTCGATATCGTCTCCAACCCGGAGTTTCTCAAGGAAGGTTCG
GCCGTCGCCGACTGCCGTCGGCCGGACCGGATCGTCATCGGCTGCGAACGCGAAGAAGTACGCGACGTGATGCGAGACCT
GTACTCGCCGTTCAACCGCAACCACGACCGCATCATGTTCATGGACCTGCGCAGCGCCGAGCTGACCAAATACGCCGCCA
ACTGCATGCTGGCGACCAAGATCAGCTTCATCAACCAGATCGCCGAACTGGCCGAGCACCTGGGCGCGGACATCGAATCG
GTACGCCAGGGCATCGGCGCCGACAGCCGCATCGGCTACCACTTCATCTACCCCGGCTGCGGTTACGGCGGCTCGTGTTT
TCCCAAGGACATGCGCGCGCTGATCCACAGCGCCGAAGAGGCGCACTGCTCCAGCGACTTGCTGCAAGCCGTGGAAGCGA
TCAACCAGCGGCAGAAACACAAGCTGTTCGAACGGATCAACGCGTTTTACAAGGGCGAACTGCGCGGCAAGACCTTCGCG
GTCTGGGGCCTGGCCTTCAAGCCGAACACCGACGACATGCGCGACGCGCCAAGCCGGGTCTTGCTCGAATCGCTGTGGGC
CGCTGGCGCCAATGTGCGGGCGTTCGACCCGGAAGCCATGCAGGAAACCCAGAACCTGTACCCGGACGAATCGAAGCTGA
TGTTGATGGGCACTCCGGAATCGGTACTCGCCGGTTCCGATGCGCTGATCATCTGCACCGAATGGCAGCAGTTCAAGGCG
CCGGACTTCGACCTGATCCAACAACGCCTCAAGGCCCCGGTGATCTTCGATGGCCGCAACCTCTACGACGCCGAACGCCT
GGCCCGTAACGGCTTCCACTACTTCCCGATGGGCCGTGGCGAATCGCGCACCTTGCCGATTCCGTTGCAGCAATGGCCGC
ACGCCTCGGACGTGGCTTGA

Upstream 100 bases:

>100_bases
CCTTCAGTTTCTCCAAATCACTGGGTGTGGCGCTGGTCATGCTCGGGGTCATCACTATCAACACTCGTCCGGCCCGTGCG
CCGGAGTTGAGGAGTTCGCC

Downstream 100 bases:

>100_bases
TCAAGTTGTCCTGTACCATTCGCCGGCAGTCCCTGATCGCAGGGCTGCTTGCATTTGTGCTGTTCATCGCCGGCGTGTAC
GGGCAGGCGCCTATCGGTTT

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKITVFGSGYVGLVQAAVLAEVGHDVVCMDIDEKKIELLRQGHVSIFEPGLASLVREGLDAGRLQFTCDEILAVQHGKVA
FIAVGTPSNEDGSADLRYVLSVGDAVARHREKPLILVEKSTVPVGTGDTLRAHLDKALVKAGRLLQFDIVSNPEFLKEGS
AVADCRRPDRIVIGCEREEVRDVMRDLYSPFNRNHDRIMFMDLRSAELTKYAANCMLATKISFINQIAELAEHLGADIES
VRQGIGADSRIGYHFIYPGCGYGGSCFPKDMRALIHSAEEAHCSSDLLQAVEAINQRQKHKLFERINAFYKGELRGKTFA
VWGLAFKPNTDDMRDAPSRVLLESLWAAGANVRAFDPEAMQETQNLYPDESKLMLMGTPESVLAGSDALIICTEWQQFKA
PDFDLIQQRLKAPVIFDGRNLYDAERLARNGFHYFPMGRGESRTLPIPLQQWPHASDVA

Sequences:

>Translated_459_residues
MKITVFGSGYVGLVQAAVLAEVGHDVVCMDIDEKKIELLRQGHVSIFEPGLASLVREGLDAGRLQFTCDEILAVQHGKVA
FIAVGTPSNEDGSADLRYVLSVGDAVARHREKPLILVEKSTVPVGTGDTLRAHLDKALVKAGRLLQFDIVSNPEFLKEGS
AVADCRRPDRIVIGCEREEVRDVMRDLYSPFNRNHDRIMFMDLRSAELTKYAANCMLATKISFINQIAELAEHLGADIES
VRQGIGADSRIGYHFIYPGCGYGGSCFPKDMRALIHSAEEAHCSSDLLQAVEAINQRQKHKLFERINAFYKGELRGKTFA
VWGLAFKPNTDDMRDAPSRVLLESLWAAGANVRAFDPEAMQETQNLYPDESKLMLMGTPESVLAGSDALIICTEWQQFKA
PDFDLIQQRLKAPVIFDGRNLYDAERLARNGFHYFPMGRGESRTLPIPLQQWPHASDVA
>Mature_459_residues
MKITVFGSGYVGLVQAAVLAEVGHDVVCMDIDEKKIELLRQGHVSIFEPGLASLVREGLDAGRLQFTCDEILAVQHGKVA
FIAVGTPSNEDGSADLRYVLSVGDAVARHREKPLILVEKSTVPVGTGDTLRAHLDKALVKAGRLLQFDIVSNPEFLKEGS
AVADCRRPDRIVIGCEREEVRDVMRDLYSPFNRNHDRIMFMDLRSAELTKYAANCMLATKISFINQIAELAEHLGADIES
VRQGIGADSRIGYHFIYPGCGYGGSCFPKDMRALIHSAEEAHCSSDLLQAVEAINQRQKHKLFERINAFYKGELRGKTFA
VWGLAFKPNTDDMRDAPSRVLLESLWAAGANVRAFDPEAMQETQNLYPDESKLMLMGTPESVLAGSDALIICTEWQQFKA
PDFDLIQQRLKAPVIFDGRNLYDAERLARNGFHYFPMGRGESRTLPIPLQQWPHASDVA

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=471, Percent_Identity=32.2717622080679, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI296040438, Length=373, Percent_Identity=32.9758713136729, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI296040443, Length=336, Percent_Identity=32.7380952380952, Blast_Score=166, Evalue=5e-41,
Organism=Escherichia coli, GI1788340, Length=364, Percent_Identity=27.7472527472527, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI48994968, Length=422, Percent_Identity=24.8815165876777, Blast_Score=122, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17560350, Length=462, Percent_Identity=33.7662337662338, Blast_Score=227, Evalue=8e-60,
Organism=Drosophila melanogaster, GI17136908, Length=469, Percent_Identity=33.6886993603412, Blast_Score=241, Evalue=6e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 50979; Mature: 50979

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITVFGSGYVGLVQAAVLAEVGHDVVCMDIDEKKIELLRQGHVSIFEPGLASLVREGLD
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCEEECCHHHHHHHCCCC
AGRLQFTCDEILAVQHGKVAFIAVGTPSNEDGSADLRYVLSVGDAVARHREKPLILVEKS
CCCEEEEHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECC
TVPVGTGDTLRAHLDKALVKAGRLLQFDIVSNPEFLKEGSAVADCRRPDRIVIGCEREEV
CCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHCCCCHHHCCCCCEEEEECCHHHH
RDVMRDLYSPFNRNHDRIMFMDLRSAELTKYAANCMLATKISFINQIAELAEHLGADIES
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRQGIGADSRIGYHFIYPGCGYGGSCFPKDMRALIHSAEEAHCSSDLLQAVEAINQRQKH
HHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLFERINAFYKGELRGKTFAVWGLAFKPNTDDMRDAPSRVLLESLWAAGANVRAFDPEAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHCCHHHHHHHHHHHCCCCCEECCHHHH
QETQNLYPDESKLMLMGTPESVLAGSDALIICTEWQQFKAPDFDLIQQRLKAPVIFDGRN
HHHHHCCCCCCCEEEEECCHHHHCCCCEEEEEECCHHCCCCCHHHHHHHHCCCEEECCCC
LYDAERLARNGFHYFPMGRGESRTLPIPLQQWPHASDVA
CHHHHHHHHCCCEECCCCCCCCCCCCCCHHHCCCCCCCC
>Mature Secondary Structure
MKITVFGSGYVGLVQAAVLAEVGHDVVCMDIDEKKIELLRQGHVSIFEPGLASLVREGLD
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCEEECCHHHHHHHCCCC
AGRLQFTCDEILAVQHGKVAFIAVGTPSNEDGSADLRYVLSVGDAVARHREKPLILVEKS
CCCEEEEHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECC
TVPVGTGDTLRAHLDKALVKAGRLLQFDIVSNPEFLKEGSAVADCRRPDRIVIGCEREEV
CCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHCCCCHHHCCCCCEEEEECCHHHH
RDVMRDLYSPFNRNHDRIMFMDLRSAELTKYAANCMLATKISFINQIAELAEHLGADIES
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRQGIGADSRIGYHFIYPGCGYGGSCFPKDMRALIHSAEEAHCSSDLLQAVEAINQRQKH
HHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLFERINAFYKGELRGKTFAVWGLAFKPNTDDMRDAPSRVLLESLWAAGANVRAFDPEAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHCCHHHHHHHHHHHCCCCCEECCHHHH
QETQNLYPDESKLMLMGTPESVLAGSDALIICTEWQQFKAPDFDLIQQRLKAPVIFDGRN
HHHHHCCCCCCCEEEEECCHHHHCCCCEEEEEECCHHCCCCCHHHHHHHHCCCEEECCCC
LYDAERLARNGFHYFPMGRGESRTLPIPLQQWPHASDVA
CHHHHHHHHCCCEECCCCCCCCCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]