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The map label for this gene is udg [H]

Identifier: 77459042

GI number: 77459042

Start: 3247908

End: 3249248

Strand: Direct

Name: udg [H]

Synonym: Pfl01_2817

Alternate gene names: 77459042

Gene position: 3247908-3249248 (Clockwise)

Preceding gene: 77459041

Following gene: 77459043

Centisome position: 50.45

GC content: 60.63

Gene sequence:

>1341_bases
ATGAATGTGAGCGTATTCGGTATTGGTTACGTAGGCCTTGTCCAGGGTGCTGCATTGGCCGAGGTCGGGCACAACGTGCT
CTGCGTCGACGTCGACGCCGGCAGGGTCGAGGCATTGAAAGAGGGCACGCTGCCGCTCTACGAGCCGGGCCTGAAAATCC
TGGTGCGCGACAACTACCAAAGCGGCCGACTGCAGTTCGGCACAGACCTGGTGGACGCCGTTCACCATGGCGATGTGCTG
TTGATCGCCGTCGGCACACCGCCCGACGAAGACGGTTCGGCGGATCTCCAATACGTGTTGAGCGTGGCGCGGACCATCGC
GCTGAACCTGGACCGGCACCAGATCATCGTCGACAAATCCACCGTGCCCGTCGGTACCGGCGATCGGGTGCGAGCCTGTA
TCGAGCAAGTATTGGCCGACAACGGTCGCGGCGATCTGACGTTCGACGTGGTTTCAAACCCGGAATTTCTCAAGGAAGGC
TGCGCGGTCGAGGACTGCATGCGCCCGGACCGGATCATCATCGGCACCGACAGCCCGCGTGCCGAAGAGGTCATGCGCGA
ACTGTATGAGCCGTTCAATCGCAGCCGCGAAAAAATCATTGTCATGGACGTTCGCAGCGCTGAACTGACCAAGTACGCCG
CCAATTGCATGCTGGCAACCAAGATCAGCTTCATGAACGAAATGGCCTGCCTCGCTGAAAAGCTCGGCGCCGACATCGAA
AAGGTGCGCCACGGCATCGGTGCCGACCCGCGCATCGGTTACCAGTTTATCTACCCAGGTCTGGGCTACGGCGGCTCGTG
TTTTCCCAAGGACGTGAAGGCGCTGATACAGGCGGCCGACGGTGTCGACATCGACGCCCGGGTGCTCAAGGCCGTGGAAG
CGCGCAACCAGGAACAGAAAGCCAGCCTCTATCGCAAGGTATTCGATCACTTCGACGGTCACCTTCGCGGCAAGACGTTT
GCCCTGTGGGGGCTGAGTTTCAAACCCAATACCGACGACATGCGCGAAGCCCCCAGCCGGGTACTGATGGAGGCTTTGTG
GCAAGCCGGCGCCAGCGTGCAGGCGTTTGATCCCAAAGCCATGGAAGAGGCCCAGCGCCTTTACGGCTCGCGCGATGACC
TGACCCTGACAGGCACCAAGGAAGCGGCGCTGAAAAATGCCGACGCCCTGATCATCGTCACCGAGTGGCAATCGTTTCGG
GCACCGGACTTCGACCAGCTCAGCCGGTTGCTCAAACAGCCGTTGATTTTCGACGGGCGCAATCTGTTCGATCCGCAGCG
TTTGAGCAAACGCGGTTTCACCTACGTCTCCGTGGGTCGGCAGACCCCTTCAGTCCTCTGA

Upstream 100 bases:

>100_bases
TTCACCCTGTTCTCGAAAAACATCTACTGAGCCCCTTTCCCGCGTCTGCCGCTCTCCTGCCCGACCGTTGATAACCGTCA
CGACGACCTGAGGTTCGACC

Downstream 100 bases:

>100_bases
AAGGAGCGGCGCCATGTTCAAACTGGAAATAGTCGGGCAGTACTCGGCGAAATTACTGGAGGCCAACCAGGCCTATTCCT
TCATCAACTTTGCCTCGATC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MNVSVFGIGYVGLVQGAALAEVGHNVLCVDVDAGRVEALKEGTLPLYEPGLKILVRDNYQSGRLQFGTDLVDAVHHGDVL
LIAVGTPPDEDGSADLQYVLSVARTIALNLDRHQIIVDKSTVPVGTGDRVRACIEQVLADNGRGDLTFDVVSNPEFLKEG
CAVEDCMRPDRIIIGTDSPRAEEVMRELYEPFNRSREKIIVMDVRSAELTKYAANCMLATKISFMNEMACLAEKLGADIE
KVRHGIGADPRIGYQFIYPGLGYGGSCFPKDVKALIQAADGVDIDARVLKAVEARNQEQKASLYRKVFDHFDGHLRGKTF
ALWGLSFKPNTDDMREAPSRVLMEALWQAGASVQAFDPKAMEEAQRLYGSRDDLTLTGTKEAALKNADALIIVTEWQSFR
APDFDQLSRLLKQPLIFDGRNLFDPQRLSKRGFTYVSVGRQTPSVL

Sequences:

>Translated_446_residues
MNVSVFGIGYVGLVQGAALAEVGHNVLCVDVDAGRVEALKEGTLPLYEPGLKILVRDNYQSGRLQFGTDLVDAVHHGDVL
LIAVGTPPDEDGSADLQYVLSVARTIALNLDRHQIIVDKSTVPVGTGDRVRACIEQVLADNGRGDLTFDVVSNPEFLKEG
CAVEDCMRPDRIIIGTDSPRAEEVMRELYEPFNRSREKIIVMDVRSAELTKYAANCMLATKISFMNEMACLAEKLGADIE
KVRHGIGADPRIGYQFIYPGLGYGGSCFPKDVKALIQAADGVDIDARVLKAVEARNQEQKASLYRKVFDHFDGHLRGKTF
ALWGLSFKPNTDDMREAPSRVLMEALWQAGASVQAFDPKAMEEAQRLYGSRDDLTLTGTKEAALKNADALIIVTEWQSFR
APDFDQLSRLLKQPLIFDGRNLFDPQRLSKRGFTYVSVGRQTPSVL
>Mature_446_residues
MNVSVFGIGYVGLVQGAALAEVGHNVLCVDVDAGRVEALKEGTLPLYEPGLKILVRDNYQSGRLQFGTDLVDAVHHGDVL
LIAVGTPPDEDGSADLQYVLSVARTIALNLDRHQIIVDKSTVPVGTGDRVRACIEQVLADNGRGDLTFDVVSNPEFLKEG
CAVEDCMRPDRIIIGTDSPRAEEVMRELYEPFNRSREKIIVMDVRSAELTKYAANCMLATKISFMNEMACLAEKLGADIE
KVRHGIGADPRIGYQFIYPGLGYGGSCFPKDVKALIQAADGVDIDARVLKAVEARNQEQKASLYRKVFDHFDGHLRGKTF
ALWGLSFKPNTDDMREAPSRVLMEALWQAGASVQAFDPKAMEEAQRLYGSRDDLTLTGTKEAALKNADALIIVTEWQSFR
APDFDQLSRLLKQPLIFDGRNLFDPQRLSKRGFTYVSVGRQTPSVL

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=471, Percent_Identity=34.3949044585987, Blast_Score=255, Evalue=5e-68,
Organism=Homo sapiens, GI296040438, Length=371, Percent_Identity=34.5013477088949, Blast_Score=208, Evalue=9e-54,
Organism=Homo sapiens, GI296040443, Length=321, Percent_Identity=35.202492211838, Blast_Score=178, Evalue=9e-45,
Organism=Escherichia coli, GI1788340, Length=385, Percent_Identity=27.5324675324675, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI48994968, Length=441, Percent_Identity=26.530612244898, Blast_Score=143, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17560350, Length=463, Percent_Identity=33.2613390928726, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI17136908, Length=470, Percent_Identity=32.9787234042553, Blast_Score=245, Evalue=5e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49155; Mature: 49155

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSVFGIGYVGLVQGAALAEVGHNVLCVDVDAGRVEALKEGTLPLYEPGLKILVRDNYQ
CCEEEEECCHHHHHCCHHHHHCCCCEEEEECCCCHHHHHHCCCCCEECCCCEEEEECCCC
SGRLQFGTDLVDAVHHGDVLLIAVGTPPDEDGSADLQYVLSVARTIALNLDRHQIIVDKS
CCCEEECHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTGDRVRACIEQVLADNGRGDLTFDVVSNPEFLKEGCAVEDCMRPDRIIIGTDSPR
CCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCCH
AEEVMRELYEPFNRSREKIIVMDVRSAELTKYAANCMLATKISFMNEMACLAEKLGADIE
HHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KVRHGIGADPRIGYQFIYPGLGYGGSCFPKDVKALIQAADGVDIDARVLKAVEARNQEQK
HHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHH
ASLYRKVFDHFDGHLRGKTFALWGLSFKPNTDDMREAPSRVLMEALWQAGASVQAFDPKA
HHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCHH
MEEAQRLYGSRDDLTLTGTKEAALKNADALIIVTEWQSFRAPDFDQLSRLLKQPLIFDGR
HHHHHHHHCCCCCEEEECCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEECCC
NLFDPQRLSKRGFTYVSVGRQTPSVL
CCCCHHHHHHCCCEEEEECCCCCCCC
>Mature Secondary Structure
MNVSVFGIGYVGLVQGAALAEVGHNVLCVDVDAGRVEALKEGTLPLYEPGLKILVRDNYQ
CCEEEEECCHHHHHCCHHHHHCCCCEEEEECCCCHHHHHHCCCCCEECCCCEEEEECCCC
SGRLQFGTDLVDAVHHGDVLLIAVGTPPDEDGSADLQYVLSVARTIALNLDRHQIIVDKS
CCCEEECHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTGDRVRACIEQVLADNGRGDLTFDVVSNPEFLKEGCAVEDCMRPDRIIIGTDSPR
CCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCCH
AEEVMRELYEPFNRSREKIIVMDVRSAELTKYAANCMLATKISFMNEMACLAEKLGADIE
HHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KVRHGIGADPRIGYQFIYPGLGYGGSCFPKDVKALIQAADGVDIDARVLKAVEARNQEQK
HHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHH
ASLYRKVFDHFDGHLRGKTFALWGLSFKPNTDDMREAPSRVLMEALWQAGASVQAFDPKA
HHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCHH
MEEAQRLYGSRDDLTLTGTKEAALKNADALIIVTEWQSFRAPDFDQLSRLLKQPLIFDGR
HHHHHHHHCCCCCEEEECCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEECCC
NLFDPQRLSKRGFTYVSVGRQTPSVL
CCCCHHHHHHCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]