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The map label for this gene is gufA [H]

Identifier: 77459012

GI number: 77459012

Start: 3213087

End: 3214016

Strand: Reverse

Name: gufA [H]

Synonym: Pfl01_2787

Alternate gene names: 77459012

Gene position: 3214016-3213087 (Counterclockwise)

Preceding gene: 77459013

Following gene: 77459011

Centisome position: 49.92

GC content: 58.6

Gene sequence:

>930_bases
ATGTCCGAGCCGTTGACCTCATCTGGCGCAACACTTCGCTCACGGTTTGTTCGACTCTCAAAATCCGGATGGGGCGGGTT
AGCCTTCTGGTCAATTCTGATTGGCGTGACGCTTTGCTTGCTGATCAGCGGGTACGGCGCCTTCGTCGGCGCCAACAAAC
AAAATCTGCACTTTGCATTTCTCGGCGGCATGTCAGGCTTCGCTGCCACGGCCATAGGTGCGTTGGCAGCGATTGCGTTA
CGCGATATCGCCGCCAGAACGCAGGACATCATGCTCGGCTTCGCTGCCGGGATGATGCTGGCCGCCAGTTCGTTTTCGCT
CATTCTTCCGGGCATCGAAGCCGCCCAGGCGCTGTACGGTAACCAGTTGCTCGCAGCCTGTGTCGTCGTTGCAGGATTGG
GATTGGGGGTAGCGCTGATGATCGGTCTGGATCGCTTCGTGCCTCACGAACATGAGAAAAGCGGTCGCCGTGGGCCCGAG
GCGCAGCGCATCAATCGTGTATGGCTGTTTGTCCTGGCAATCACGCTGCATAACTTGCCGGAGGGGATGGCCATTGGAGT
GAGCTTTGCCAATGGCGATATGAAGGTGGGATTGCCGCTAACCACTGCCATCGCCATTCAAGACATTCCCGAAGGCCTGG
CTGTGGCGCTTGCGTTACGCGTGACCGGGATTTCAGCGCTTCGCGCTGCGCTTATTGCGGTGGGCTCAGGGTTGATGGAG
CCCATTGGCGCGATCGTCGGCTTGGGGGTTTCGAGCAGCTTCGCATTGGGATATCCCATAGCGCTCGGTCTGGCGGCGGG
CGCGATGATTTTTGTGGTGTCCCATGAGGTCATTCCCGAGACCCATCGCAACGGTCATGAGACACCTGCGACCTTGGGGT
TGATGCTCGGTTTCGGGGTCATGATGTTTCTCGACACGGCTTTGGGTTGA

Upstream 100 bases:

>100_bases
GACCTGGGGGCGGGTGTGCAAGGCGAACCACAACCTTAACGACGCGACCGCACGCCAAAAGGCGTGCGGTTTTTCCATCT
CAAGAAAACAGGAGGGTGCG

Downstream 100 bases:

>100_bases
CCCTTTACCTCCCATCCATCATTGGACGGCGTGGTTGAAGAAACTGGAAGCAAAAATCCGACGGTAGGCGTCGCGATCCC
ACCTGCACTGCCTTTCAATT

Product: Zinc transporter ZIP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSEPLTSSGATLRSRFVRLSKSGWGGLAFWSILIGVTLCLLISGYGAFVGANKQNLHFAFLGGMSGFAATAIGALAAIAL
RDIAARTQDIMLGFAAGMMLAASSFSLILPGIEAAQALYGNQLLAACVVVAGLGLGVALMIGLDRFVPHEHEKSGRRGPE
AQRINRVWLFVLAITLHNLPEGMAIGVSFANGDMKVGLPLTTAIAIQDIPEGLAVALALRVTGISALRAALIAVGSGLME
PIGAIVGLGVSSSFALGYPIALGLAAGAMIFVVSHEVIPETHRNGHETPATLGLMLGFGVMMFLDTALG

Sequences:

>Translated_309_residues
MSEPLTSSGATLRSRFVRLSKSGWGGLAFWSILIGVTLCLLISGYGAFVGANKQNLHFAFLGGMSGFAATAIGALAAIAL
RDIAARTQDIMLGFAAGMMLAASSFSLILPGIEAAQALYGNQLLAACVVVAGLGLGVALMIGLDRFVPHEHEKSGRRGPE
AQRINRVWLFVLAITLHNLPEGMAIGVSFANGDMKVGLPLTTAIAIQDIPEGLAVALALRVTGISALRAALIAVGSGLME
PIGAIVGLGVSSSFALGYPIALGLAAGAMIFVVSHEVIPETHRNGHETPATLGLMLGFGVMMFLDTALG
>Mature_308_residues
SEPLTSSGATLRSRFVRLSKSGWGGLAFWSILIGVTLCLLISGYGAFVGANKQNLHFAFLGGMSGFAATAIGALAAIALR
DIAARTQDIMLGFAAGMMLAASSFSLILPGIEAAQALYGNQLLAACVVVAGLGLGVALMIGLDRFVPHEHEKSGRRGPEA
QRINRVWLFVLAITLHNLPEGMAIGVSFANGDMKVGLPLTTAIAIQDIPEGLAVALALRVTGISALRAALIAVGSGLMEP
IGAIVGLGVSSSFALGYPIALGLAAGAMIFVVSHEVIPETHRNGHETPATLGLMLGFGVMMFLDTALG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577422, Length=160, Percent_Identity=41.25, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI229577418, Length=160, Percent_Identity=41.25, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI1789419, Length=247, Percent_Identity=33.1983805668016, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17507805, Length=317, Percent_Identity=33.7539432176656, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24652846, Length=175, Percent_Identity=41.7142857142857, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 31764; Mature: 31633

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPLTSSGATLRSRFVRLSKSGWGGLAFWSILIGVTLCLLISGYGAFVGANKQNLHFAF
CCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHEECCCCCCEEEEE
LGGMSGFAATAIGALAAIALRDIAARTQDIMLGFAAGMMLAASSFSLILPGIEAAQALYG
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHH
NQLLAACVVVAGLGLGVALMIGLDRFVPHEHEKSGRRGPEAQRINRVWLFVLAITLHNLP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
EGMAIGVSFANGDMKVGLPLTTAIAIQDIPEGLAVALALRVTGISALRAALIAVGSGLME
CCEEEEEEEECCCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
PIGAIVGLGVSSSFALGYPIALGLAAGAMIFVVSHEVIPETHRNGHETPATLGLMLGFGV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEHHHHHCCCCCCCCCCCHHHHHHHHHHHH
MMFLDTALG
HHHHHHHCC
>Mature Secondary Structure 
SEPLTSSGATLRSRFVRLSKSGWGGLAFWSILIGVTLCLLISGYGAFVGANKQNLHFAF
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHEECCCCCCEEEEE
LGGMSGFAATAIGALAAIALRDIAARTQDIMLGFAAGMMLAASSFSLILPGIEAAQALYG
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHH
NQLLAACVVVAGLGLGVALMIGLDRFVPHEHEKSGRRGPEAQRINRVWLFVLAITLHNLP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
EGMAIGVSFANGDMKVGLPLTTAIAIQDIPEGLAVALALRVTGISALRAALIAVGSGLME
CCEEEEEEEECCCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
PIGAIVGLGVSSSFALGYPIALGLAAGAMIFVVSHEVIPETHRNGHETPATLGLMLGFGV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEHHHHHCCCCCCCCCCCHHHHHHHHHHHH
MMFLDTALG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]