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The map label for this gene is dltE [H]

Identifier: 77458994

GI number: 77458994

Start: 3194525

End: 3195283

Strand: Reverse

Name: dltE [H]

Synonym: Pfl01_2769

Alternate gene names: 77458994

Gene position: 3195283-3194525 (Counterclockwise)

Preceding gene: 77458996

Following gene: 77458993

Centisome position: 49.63

GC content: 53.36

Gene sequence:

>759_bases
ATGAACAGCACTGGCAACACGATTCTGGTTACAGGCGGCACCTCAGGCATAGGCCTCGGGCTTGCGCTACGGCTTCATAA
AGCGGGCAACAACGTCATCATCGCGGGACGTCGCAAGGCTCTGCTCGACAAAATCGTGTCGGAAAATCCTGGCATTGAAT
CAGTATTGCTGGACGTTTCTGATGCTCATTCCATCCAGCGCACCAGCGAAGCGCTTGCGATCAGCCATCCAAATCTTAAC
GTTCTCATCAACAACGCAGGGATCATGCATTGGGAGGATCTGACTGATCCGGGATACTTGAGTACAGCGGAAGATATCGT
GACAACGAACCTGCTAGGCACGATTCGTATGGTGTATGCGTTTACTCCCCAACTAATCAAGCAGCCTGGCGCGACAGTGA
TCAATGTCAGTTCATCTTTGGCATTTGTCCCGCTGCCAGCCACGCCCACCTACAGCGCAACCAAAGCGGCAGTTCACTCG
TTCACTCAAAGTCTTCGAGTGCAGCTGGAAGCCTCGCCAGTTGAGGTTATCGAACTTGCGCCACCGGGTGTGCGTACCAC
ATTGCTCGGCCAGGAAAACGACGAGCATGCGATGCCGTTGGAGGAGTTTTTGGATGAAGTCTTCGAACTGCTAAAGATTT
CTCCCACTCCACCTGAACTCGTCGTTGAGCGGGCTAAGCCCCTGCGGTTTGCTGAGGCAAGTGGGTCACATGATGACGTG
CTGAAAATGCTTGCGGGATACAAACCACCGGCAGAATGA

Upstream 100 bases:

>100_bases
CATGAATAATTTTCCCTCATTGCATTGCTAAGCGGACAACTGTCCGGTACGGTTTGCAAGTGGACACTTGTCCGCTTAAA
TATCGTTTCTGGAGTTTACT

Downstream 100 bases:

>100_bases
GTCATTGCTCTGAAGCGCGCCCTGTGTCCAGGTGAGCAGATTGCATCTGCTTACCTGCAGGCCGAATCGCTCAATCGGTG
TGTCCACAATTCCGCTGCCT

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MNSTGNTILVTGGTSGIGLGLALRLHKAGNNVIIAGRRKALLDKIVSENPGIESVLLDVSDAHSIQRTSEALAISHPNLN
VLINNAGIMHWEDLTDPGYLSTAEDIVTTNLLGTIRMVYAFTPQLIKQPGATVINVSSSLAFVPLPATPTYSATKAAVHS
FTQSLRVQLEASPVEVIELAPPGVRTTLLGQENDEHAMPLEEFLDEVFELLKISPTPPELVVERAKPLRFAEASGSHDDV
LKMLAGYKPPAE

Sequences:

>Translated_252_residues
MNSTGNTILVTGGTSGIGLGLALRLHKAGNNVIIAGRRKALLDKIVSENPGIESVLLDVSDAHSIQRTSEALAISHPNLN
VLINNAGIMHWEDLTDPGYLSTAEDIVTTNLLGTIRMVYAFTPQLIKQPGATVINVSSSLAFVPLPATPTYSATKAAVHS
FTQSLRVQLEASPVEVIELAPPGVRTTLLGQENDEHAMPLEEFLDEVFELLKISPTPPELVVERAKPLRFAEASGSHDDV
LKMLAGYKPPAE
>Mature_252_residues
MNSTGNTILVTGGTSGIGLGLALRLHKAGNNVIIAGRRKALLDKIVSENPGIESVLLDVSDAHSIQRTSEALAISHPNLN
VLINNAGIMHWEDLTDPGYLSTAEDIVTTNLLGTIRMVYAFTPQLIKQPGATVINVSSSLAFVPLPATPTYSATKAAVHS
FTQSLRVQLEASPVEVIELAPPGVRTTLLGQENDEHAMPLEEFLDEVFELLKISPTPPELVVERAKPLRFAEASGSHDDV
LKMLAGYKPPAE

Specific function: Unknown

COG id: COG3967

COG function: function code M; Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=24.6073298429319, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7706318, Length=188, Percent_Identity=27.6595744680851, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI7705925, Length=213, Percent_Identity=30.5164319248826, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI7705855, Length=191, Percent_Identity=27.7486910994764, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI32483357, Length=188, Percent_Identity=27.1276595744681, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4557649, Length=196, Percent_Identity=25, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI40254992, Length=206, Percent_Identity=27.6699029126214, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI44680136, Length=185, Percent_Identity=30.2702702702703, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI44680133, Length=185, Percent_Identity=30.2702702702703, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI17738292, Length=185, Percent_Identity=30.2702702702703, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI225579078, Length=268, Percent_Identity=30.2238805970149, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI226371731, Length=207, Percent_Identity=24.6376811594203, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=29.7752808988764, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI87082160, Length=183, Percent_Identity=27.8688524590164, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786701, Length=193, Percent_Identity=25.3886010362694, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI87082100, Length=235, Percent_Identity=28.0851063829787, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790717, Length=191, Percent_Identity=28.7958115183246, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786812, Length=188, Percent_Identity=26.5957446808511, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1787335, Length=200, Percent_Identity=26.5, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=205, Percent_Identity=28.780487804878, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI115534660, Length=196, Percent_Identity=31.6326530612245, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=205, Percent_Identity=27.3170731707317, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=217, Percent_Identity=29.0322580645161, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=189, Percent_Identity=29.1005291005291, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=187, Percent_Identity=29.9465240641711, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24644339, Length=210, Percent_Identity=29.0476190476191, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24651139, Length=261, Percent_Identity=27.5862068965517, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=29.4416243654822, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357041, Length=184, Percent_Identity=30.9782608695652, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI23397609, Length=188, Percent_Identity=32.4468085106383, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28571526, Length=183, Percent_Identity=31.6939890710383, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24643142, Length=193, Percent_Identity=34.1968911917098, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24665243, Length=221, Percent_Identity=27.1493212669683, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221331218, Length=221, Percent_Identity=27.1493212669683, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI116007236, Length=237, Percent_Identity=27.8481012658228, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640442, Length=204, Percent_Identity=27.9411764705882, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24665247, Length=228, Percent_Identity=25.8771929824561, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221331216, Length=228, Percent_Identity=25.8771929824561, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19921754, Length=206, Percent_Identity=31.0679611650485, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24580925, Length=197, Percent_Identity=27.4111675126904, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24639444, Length=169, Percent_Identity=33.7278106508876, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281364494, Length=198, Percent_Identity=26.2626262626263, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26942; Mature: 26942

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTGNTILVTGGTSGIGLGLALRLHKAGNNVIIAGRRKALLDKIVSENPGIESVLLDVS
CCCCCCEEEEECCCCCCCEEEEEEEEECCCCEEEECCHHHHHHHHHHCCCCHHEEEEECH
DAHSIQRTSEALAISHPNLNVLINNAGIMHWEDLTDPGYLSTAEDIVTTNLLGTIRMVYA
HHHHHHHHCCEEEEECCCEEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FTPQLIKQPGATVINVSSSLAFVPLPATPTYSATKAAVHSFTQSLRVQLEASPVEVIELA
HCHHHHHCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHEEEEECCCEEEEEEC
PPGVRTTLLGQENDEHAMPLEEFLDEVFELLKISPTPPELVVERAKPLRFAEASGSHDDV
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEECCCCCHHHH
LKMLAGYKPPAE
HHHHHCCCCCCC
>Mature Secondary Structure
MNSTGNTILVTGGTSGIGLGLALRLHKAGNNVIIAGRRKALLDKIVSENPGIESVLLDVS
CCCCCCEEEEECCCCCCCEEEEEEEEECCCCEEEECCHHHHHHHHHHCCCCHHEEEEECH
DAHSIQRTSEALAISHPNLNVLINNAGIMHWEDLTDPGYLSTAEDIVTTNLLGTIRMVYA
HHHHHHHHCCEEEEECCCEEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FTPQLIKQPGATVINVSSSLAFVPLPATPTYSATKAAVHSFTQSLRVQLEASPVEVIELA
HCHHHHHCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHEEEEECCCEEEEEEC
PPGVRTTLLGQENDEHAMPLEEFLDEVFELLKISPTPPELVVERAKPLRFAEASGSHDDV
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEECCCCCHHHH
LKMLAGYKPPAE
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 7797557 [H]