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The map label for this gene is aofH [H]

Identifier: 77458967

GI number: 77458967

Start: 3158821

End: 3160293

Strand: Reverse

Name: aofH [H]

Synonym: Pfl01_2742

Alternate gene names: 77458967

Gene position: 3160293-3158821 (Counterclockwise)

Preceding gene: 77458968

Following gene: 77458966

Centisome position: 49.09

GC content: 61.71

Gene sequence:

>1473_bases
ATGAGTACTGACGCCCCTCCCGATCTGAAGCGAAGACAATTACTCAAACTGGCCGGTGCAACCGCCGCCGTAGGATCGAT
CGGTTTGAACCTTGGCCTGGCCAATGCCGCCGATGCGCTGCAAAAGGACAGTTCCGACGATGTATTTGATGTGGTGATCA
TCGGTGCCGGCCTGGCTGGTTTGACCGCCGCCCGTGATCTGCATCTGGCAGGCTGTGAGTCGCTGCTGGTGCTTGAAGCG
CGTGATCGTGTCGGCGGCCGCACCCTCAATCATGACTTGGGCTCCGGCTACATCTCCGAAGCCGGAGGTCAGTGGATCGG
TCCAGGACAAACCGCCGTAGCGGATCTGGCCCGTGAGCTTGAGGTCGGCACCTTTCCCAGTTTCTATGACGGGGAAACCG
TGATCCTCGGGGGCGATGGACGTGTCGCTGTCGATTTGAAAGGCACCTTCGGTACCGACGAAAGCGTCTCGGCAAAACTC
AGCGAGCTGTCGCGTGATGTGCCGTGCGGTGCGCCATGGAAATCCCCCAGGGTGGCCGAACTGGACAAGCTCTCGGCGGG
CGACTGGCTCGCTCAGCAAAACATCAAGCCGGAAGATCGCGCAGGGTGGAATGCCAGCTTCCTCCTGACCTGCGGTGTCA
CGCCGGCGAAGATGGGCTTCTTGCATTTTCTGTCGATGATCAATTCGGCCGGCAGCGAATACATGCGGCTCGATTCGATC
AAGGACAGCGCGCAAGGCACGCGGATCGTCGGCGGTTCACAGGTTCTCAGCAGCAAAATGGCGCAATTGTTGGGCGACAG
GGTTCGCTTGTCGTGCCCAGTGCGCAAAATTGCTGACTGGAACCGCGACATCGTCAGACTGCAAACGGATCAGGGCGAGA
TCCGCGCCCGCCGGGTGATCATGGCGATTCATCCCGCGCTGTGCCAACGCCTGCAATTCGATCCACCGCTGCCCGAAGCT
CGCGCCGCCCTGCAGCGGGCCTGGCCAGCGCACTCGCCGGCACGCAAGACCGCAATGGTTTACCCGCGGCCTTTCTGGCG
TGACAAGGGCTTGAACGGCCACATCATTCAGGTCGGTGGGCCAGTCATCTGGGCCTACGACAACTCGCCGCCAAACGGCG
AAATCGGCGTGATCAATGCATTCATTCTGAATGCCGCAGCCCCCACCGACCCCGAAGCCGCGAAGCGTGTGCAGACCGAA
ATCTATGCACGCGCCCTGGGGGACGCAGCGCTTGAGCCGGTTTCCTACCACGATCACGACTGGGCGCATTTCGACCCGTG
GACCATCACGTGCGTGTCGCCGATTCCTCCCGGTTTCTGGTCGACACATGGCGAGGCACTGCGTCCGCCGTGCGGCAATC
TGTTCTGGTCGGGCACCGAAACCGCTGACATCTGGGCAGGTTACATGGACGGTGCCGTGCGCGCCGGACGCCATAGCGCC
TTGCAGGTGCTCAACGCGTTACGTCGGGCATAG

Upstream 100 bases:

>100_bases
CAAACGAATGTTTGCGTTCTCGTTACCACTTTTTTACTGCCGCACCCACGCTCGGCCACGGGCGTTCAATCCAACAATAA
CGTGATGTGAGGCATCGAAC

Downstream 100 bases:

>100_bases
GAGGCGGCAATGAAAAAAAACATAGCGCTTGGCGTCATCGCGCTCATTGCGGTGCTGGTGGTGGTTTTCGGCCGTGATCT
GCTCGACCTGTATCGGCTGC

Product: twin-arginine translocation pathway signal protein

Products: RCHO; NH3; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSTDAPPDLKRRQLLKLAGATAAVGSIGLNLGLANAADALQKDSSDDVFDVVIIGAGLAGLTAARDLHLAGCESLLVLEA
RDRVGGRTLNHDLGSGYISEAGGQWIGPGQTAVADLARELEVGTFPSFYDGETVILGGDGRVAVDLKGTFGTDESVSAKL
SELSRDVPCGAPWKSPRVAELDKLSAGDWLAQQNIKPEDRAGWNASFLLTCGVTPAKMGFLHFLSMINSAGSEYMRLDSI
KDSAQGTRIVGGSQVLSSKMAQLLGDRVRLSCPVRKIADWNRDIVRLQTDQGEIRARRVIMAIHPALCQRLQFDPPLPEA
RAALQRAWPAHSPARKTAMVYPRPFWRDKGLNGHIIQVGGPVIWAYDNSPPNGEIGVINAFILNAAAPTDPEAAKRVQTE
IYARALGDAALEPVSYHDHDWAHFDPWTITCVSPIPPGFWSTHGEALRPPCGNLFWSGTETADIWAGYMDGAVRAGRHSA
LQVLNALRRA

Sequences:

>Translated_490_residues
MSTDAPPDLKRRQLLKLAGATAAVGSIGLNLGLANAADALQKDSSDDVFDVVIIGAGLAGLTAARDLHLAGCESLLVLEA
RDRVGGRTLNHDLGSGYISEAGGQWIGPGQTAVADLARELEVGTFPSFYDGETVILGGDGRVAVDLKGTFGTDESVSAKL
SELSRDVPCGAPWKSPRVAELDKLSAGDWLAQQNIKPEDRAGWNASFLLTCGVTPAKMGFLHFLSMINSAGSEYMRLDSI
KDSAQGTRIVGGSQVLSSKMAQLLGDRVRLSCPVRKIADWNRDIVRLQTDQGEIRARRVIMAIHPALCQRLQFDPPLPEA
RAALQRAWPAHSPARKTAMVYPRPFWRDKGLNGHIIQVGGPVIWAYDNSPPNGEIGVINAFILNAAAPTDPEAAKRVQTE
IYARALGDAALEPVSYHDHDWAHFDPWTITCVSPIPPGFWSTHGEALRPPCGNLFWSGTETADIWAGYMDGAVRAGRHSA
LQVLNALRRA
>Mature_489_residues
STDAPPDLKRRQLLKLAGATAAVGSIGLNLGLANAADALQKDSSDDVFDVVIIGAGLAGLTAARDLHLAGCESLLVLEAR
DRVGGRTLNHDLGSGYISEAGGQWIGPGQTAVADLARELEVGTFPSFYDGETVILGGDGRVAVDLKGTFGTDESVSAKLS
ELSRDVPCGAPWKSPRVAELDKLSAGDWLAQQNIKPEDRAGWNASFLLTCGVTPAKMGFLHFLSMINSAGSEYMRLDSIK
DSAQGTRIVGGSQVLSSKMAQLLGDRVRLSCPVRKIADWNRDIVRLQTDQGEIRARRVIMAIHPALCQRLQFDPPLPEAR
AALQRAWPAHSPARKTAMVYPRPFWRDKGLNGHIIQVGGPVIWAYDNSPPNGEIGVINAFILNAAAPTDPEAAKRVQTEI
YARALGDAALEPVSYHDHDWAHFDPWTITCVSPIPPGFWSTHGEALRPPCGNLFWSGTETADIWAGYMDGAVRAGRHSAL
QVLNALRRA

Specific function: Unknown

COG id: COG1231

COG function: function code E; Monoamine oxidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin monoamine oxidase family [H]

Homologues:

Organism=Homo sapiens, GI4557735, Length=470, Percent_Identity=30.8510638297872, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI38202207, Length=457, Percent_Identity=32.8227571115974, Blast_Score=206, Evalue=6e-53,
Organism=Drosophila melanogaster, GI21355313, Length=77, Percent_Identity=45.4545454545455, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001613
- InterPro:   IPR002937 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: 1.4.3.4

Molecular weight: Translated: 52657; Mature: 52526

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDAPPDLKRRQLLKLAGATAAVGSIGLNLGLANAADALQKDSSDDVFDVVIIGAGLAG
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECCCHHH
LTAARDLHLAGCESLLVLEARDRVGGRTLNHDLGSGYISEAGGQWIGPGQTAVADLAREL
HHHHHHHHHHCCCEEEEEEECCCCCCEEECCCCCCCHHHHCCCCCCCCCHHHHHHHHHHH
EVGTFPSFYDGETVILGGDGRVAVDLKGTFGTDESVSAKLSELSRDVPCGAPWKSPRVAE
CCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHH
LDKLSAGDWLAQQNIKPEDRAGWNASFLLTCGVTPAKMGFLHFLSMINSAGSEYMRLDSI
HHHCCCCCHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCHHHEEHHHH
KDSAQGTRIVGGSQVLSSKMAQLLGDRVRLSCPVRKIADWNRDIVRLQTDQGEIRARRVI
HCCCCCCEEECHHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCEEEEECCCCHHHHHHHH
MAIHPALCQRLQFDPPLPEARAALQRAWPAHSPARKTAMVYPRPFWRDKGLNGHIIQVGG
HHHCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECC
PVIWAYDNSPPNGEIGVINAFILNAAAPTDPEAAKRVQTEIYARALGDAALEPVSYHDHD
EEEEEECCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
WAHFDPWTITCVSPIPPGFWSTHGEALRPPCGNLFWSGTETADIWAGYMDGAVRAGRHSA
CCEECCEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCHHHH
LQVLNALRRA
HHHHHHHHCC
>Mature Secondary Structure 
STDAPPDLKRRQLLKLAGATAAVGSIGLNLGLANAADALQKDSSDDVFDVVIIGAGLAG
CCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECCCHHH
LTAARDLHLAGCESLLVLEARDRVGGRTLNHDLGSGYISEAGGQWIGPGQTAVADLAREL
HHHHHHHHHHCCCEEEEEEECCCCCCEEECCCCCCCHHHHCCCCCCCCCHHHHHHHHHHH
EVGTFPSFYDGETVILGGDGRVAVDLKGTFGTDESVSAKLSELSRDVPCGAPWKSPRVAE
CCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHH
LDKLSAGDWLAQQNIKPEDRAGWNASFLLTCGVTPAKMGFLHFLSMINSAGSEYMRLDSI
HHHCCCCCHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCHHHEEHHHH
KDSAQGTRIVGGSQVLSSKMAQLLGDRVRLSCPVRKIADWNRDIVRLQTDQGEIRARRVI
HCCCCCCEEECHHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCEEEEECCCCHHHHHHHH
MAIHPALCQRLQFDPPLPEARAALQRAWPAHSPARKTAMVYPRPFWRDKGLNGHIIQVGG
HHHCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECC
PVIWAYDNSPPNGEIGVINAFILNAAAPTDPEAAKRVQTEIYARALGDAALEPVSYHDHD
EEEEEECCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
WAHFDPWTITCVSPIPPGFWSTHGEALRPPCGNLFWSGTETADIWAGYMDGAVRAGRHSA
CCEECCEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCHHHH
LQVLNALRRA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RCH2NH2; H2O; O2

Specific reaction: RCH2NH2 + H2O + O2 = RCHO + NH3 + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]