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The map label for this gene is dltE [H]

Identifier: 77458940

GI number: 77458940

Start: 3132125

End: 3132889

Strand: Reverse

Name: dltE [H]

Synonym: Pfl01_2715

Alternate gene names: 77458940

Gene position: 3132889-3132125 (Counterclockwise)

Preceding gene: 77458941

Following gene: 77458939

Centisome position: 48.66

GC content: 59.35

Gene sequence:

>765_bases
ATGAAACTCAGCGCTAACACGATCTTCATCACCGGCGGCACCTCCGGCATTGGCCGCGCTTTGGCCGAGGCATTTCACCA
GCGCGGCAATCAGGTCATCATCGCGGGCCGTCGACAGGCCCTGCTGGATGAGATCGCCCGGGCCAATCCCGGTATCGACA
CGGTCCAGCTGGACATCAATGACCCGCAGCAAATCAAGGATGTCGCCCAGGAAGTCATACGCCGCCACCCCTCGCTGAAC
GTGATCATCAATAACGCCGGGATCATGCCGTTCGATAATCCAGCCTCGGGTGATTACGACGACGAACAGGCGGTGAGTCT
TTTGCAAACCAACCTGCTCGGCCCGGTGCGTGTCAGCGCCGCATTCGTCGAGCACCTCAAGCGTCAACCCGAAGCCTTCA
TCATCAACAACAGCTCCGTGCTGGCCTATCTGCCACTGGCTGCGACAGCGTTGTACTCGGCGACGAAGGCGGCCATTCAC
TCCTACTCGCTGTCGCAACGCTTCACCCTGCGCGACACCCGCGTAAAAGTGCTGGAGATCGCGCCGCCATGGGTCGACAC
CGACCTGATTCACAAAAGCGGCGATGAACGCGCCATGCCGCTCGACGAATTCATTCGGGAAACCCTGGAAAAACTCGAAA
CGGCGACCACGGAAGTGTTGGTGGATCGGGTCGTCCCGTTGCGAGCCAACCAAGGCATTAATGAGCATGCGCTGATCAAT
CAGTTCAACCAGGCACTGGAGGAGAACCCGATTCCGGTCGCCTGA

Upstream 100 bases:

>100_bases
GTTACGAAGCCAGCCGCCAGGCCTTGTTCTCCGAGCTTTCGAGCAACCGGCTCGCGCCGCGCTACAACGCCAACTGATCG
CTATCAAAAGGATATGAATC

Downstream 100 bases:

>100_bases
GTTGAAGCCATCTGTCGTCAAGGCTGCCAGCCCTCCCTGATGGAAGGCTGGCCGTTTTGTATTTTCCGCAAAATGCGGAA
AGTCTTCCTGCGATCTGCTT

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKLSANTIFITGGTSGIGRALAEAFHQRGNQVIIAGRRQALLDEIARANPGIDTVQLDINDPQQIKDVAQEVIRRHPSLN
VIINNAGIMPFDNPASGDYDDEQAVSLLQTNLLGPVRVSAAFVEHLKRQPEAFIINNSSVLAYLPLAATALYSATKAAIH
SYSLSQRFTLRDTRVKVLEIAPPWVDTDLIHKSGDERAMPLDEFIRETLEKLETATTEVLVDRVVPLRANQGINEHALIN
QFNQALEENPIPVA

Sequences:

>Translated_254_residues
MKLSANTIFITGGTSGIGRALAEAFHQRGNQVIIAGRRQALLDEIARANPGIDTVQLDINDPQQIKDVAQEVIRRHPSLN
VIINNAGIMPFDNPASGDYDDEQAVSLLQTNLLGPVRVSAAFVEHLKRQPEAFIINNSSVLAYLPLAATALYSATKAAIH
SYSLSQRFTLRDTRVKVLEIAPPWVDTDLIHKSGDERAMPLDEFIRETLEKLETATTEVLVDRVVPLRANQGINEHALIN
QFNQALEENPIPVA
>Mature_254_residues
MKLSANTIFITGGTSGIGRALAEAFHQRGNQVIIAGRRQALLDEIARANPGIDTVQLDINDPQQIKDVAQEVIRRHPSLN
VIINNAGIMPFDNPASGDYDDEQAVSLLQTNLLGPVRVSAAFVEHLKRQPEAFIINNSSVLAYLPLAATALYSATKAAIH
SYSLSQRFTLRDTRVKVLEIAPPWVDTDLIHKSGDERAMPLDEFIRETLEKLETATTEVLVDRVVPLRANQGINEHALIN
QFNQALEENPIPVA

Specific function: Unknown

COG id: COG3967

COG function: function code M; Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=25, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4504503, Length=188, Percent_Identity=30.3191489361702, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI31542939, Length=211, Percent_Identity=26.5402843601896, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4557649, Length=215, Percent_Identity=24.1860465116279, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=27.4285714285714, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=176, Percent_Identity=29.5454545454545, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787335, Length=208, Percent_Identity=29.8076923076923, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786812, Length=192, Percent_Identity=28.6458333333333, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=200, Percent_Identity=26, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=206, Percent_Identity=29.126213592233, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=200, Percent_Identity=26, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=206, Percent_Identity=28.1553398058252, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=211, Percent_Identity=26.5402843601896, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=218, Percent_Identity=26.605504587156, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=206, Percent_Identity=25.7281553398058, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320089, Length=197, Percent_Identity=31.4720812182741, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI23397609, Length=196, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=25.5102040816327, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24651139, Length=196, Percent_Identity=29.5918367346939, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007236, Length=207, Percent_Identity=28.5024154589372, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24647946, Length=222, Percent_Identity=28.8288288288288, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24643142, Length=191, Percent_Identity=28.7958115183246, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24580925, Length=203, Percent_Identity=25.615763546798, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27928; Mature: 27928

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSANTIFITGGTSGIGRALAEAFHQRGNQVIIAGRRQALLDEIARANPGIDTVQLDIN
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCEEEEEECC
DPQQIKDVAQEVIRRHPSLNVIINNAGIMPFDNPASGDYDDEQAVSLLQTNLLGPVRVSA
CHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHH
AFVEHLKRQPEAFIINNSSVLAYLPLAATALYSATKAAIHSYSLSQRFTLRDTRVKVLEI
HHHHHHHCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEE
APPWVDTDLIHKSGDERAMPLDEFIRETLEKLETATTEVLVDRVVPLRANQGINEHALIN
CCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
QFNQALEENPIPVA
HHHHHHHCCCCCCC
>Mature Secondary Structure
MKLSANTIFITGGTSGIGRALAEAFHQRGNQVIIAGRRQALLDEIARANPGIDTVQLDIN
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCEEEEEECC
DPQQIKDVAQEVIRRHPSLNVIINNAGIMPFDNPASGDYDDEQAVSLLQTNLLGPVRVSA
CHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHH
AFVEHLKRQPEAFIINNSSVLAYLPLAATALYSATKAAIHSYSLSQRFTLRDTRVKVLEI
HHHHHHHCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEE
APPWVDTDLIHKSGDERAMPLDEFIRETLEKLETATTEVLVDRVVPLRANQGINEHALIN
CCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
QFNQALEENPIPVA
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 7797557 [H]