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The map label for this gene is nahR [H]

Identifier: 77458891

GI number: 77458891

Start: 3062577

End: 3063491

Strand: Reverse

Name: nahR [H]

Synonym: Pfl01_2666

Alternate gene names: 77458891

Gene position: 3063491-3062577 (Counterclockwise)

Preceding gene: 77458896

Following gene: 77458890

Centisome position: 47.58

GC content: 64.48

Gene sequence:

>915_bases
ATGAATCGTAATGACCTGCGTCGTGTCGACCTCAACCTGTTGATCGTGTTCGAAACGCTGATGCATGAGCGCAGCGTGAC
CCGTGCGGCGGAAAAGCTGTTCCTCGGACAGCCGGCGATCAGCGCGGCGCTATCGCGCCTGCGCGGCCTGTTCGACGATC
CCTTGTTCGTGCGCACCGGACGCAGCATGGAACCTTCCGCCCGCGCGGTGGAAATCTTCGCCCTGCTCTCCCCGGCCCTG
GACTCGATTTCGACCGCCGTCAGCCGCGCGGCGGAGTTCGATCCGGCGACCAGCACGTCGGTATTCCGCATCGGCCTGTC
GGACGATGTCGAATTCGCGCTGCTGCCGATGCTGCTCAAACGCCTGCGCGCCGAAGCACCCGGGATCGTGCTGGTGGTGC
GCCGCGTCAACTACATCCTGATGCCGGGCCTGCTCGCCTCCGGCGAAATCTCCATCGGCGTCAGCTACACCACCGACCTG
CCGGCAAACGCCAAACGCAAGGTCCTGCGCCGCAGCGCCCCCAAATTACTGCGCGCCGACACCGTGCCGGGGCCGCTGAG
CCTGGACGATTACTGCGCGCGCCCGCATGCGCTGGTGTCGTTTGCCGGCGACCTCAGTGGTTTCGTCGATGAAGAGCTGG
AAAAACTCGGGCGTAAACGGCACGTGGTACTGGCGGTGCCGCAGTTCAATGGACTGGGTACGCTGCTGGCGGGCACCGAC
ATCGTCGCGACCGTGCCCGATTACACGGCGGATGCACTGACGGCGGCGGGCGGTCTGCGCGCGGAAGACCCGCCGTTGCC
GACGCGCACGTTTGAACTGCATATGGCTTGGCGGGGGTCGCAGGATAATGATCCTGGGGAGCGATGGTTAAGGTCGCGGA
TTCAGATGTTTTTTGGGGATCCGGATAGTCTCTGA

Upstream 100 bases:

>100_bases
ACCCGGTGCAGACTACCAGCCTTTCCCCGTAAGATTCATGCCGGCCATTGTTCTCATATGGTCGCTCTCGTCAAGCTTGA
TGACTCTGCCAGGACTCCAG

Downstream 100 bases:

>100_bases
ACCGAGGACGAACATCTAAAAATGCGAATCGCTATAGCGCAAGCTCTTGCTTGCGCTTGATTTTACAAGCAGATAGCCAA
ATGCCATCATTCGCGCACCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNRNDLRRVDLNLLIVFETLMHERSVTRAAEKLFLGQPAISAALSRLRGLFDDPLFVRTGRSMEPSARAVEIFALLSPAL
DSISTAVSRAAEFDPATSTSVFRIGLSDDVEFALLPMLLKRLRAEAPGIVLVVRRVNYILMPGLLASGEISIGVSYTTDL
PANAKRKVLRRSAPKLLRADTVPGPLSLDDYCARPHALVSFAGDLSGFVDEELEKLGRKRHVVLAVPQFNGLGTLLAGTD
IVATVPDYTADALTAAGGLRAEDPPLPTRTFELHMAWRGSQDNDPGERWLRSRIQMFFGDPDSL

Sequences:

>Translated_304_residues
MNRNDLRRVDLNLLIVFETLMHERSVTRAAEKLFLGQPAISAALSRLRGLFDDPLFVRTGRSMEPSARAVEIFALLSPAL
DSISTAVSRAAEFDPATSTSVFRIGLSDDVEFALLPMLLKRLRAEAPGIVLVVRRVNYILMPGLLASGEISIGVSYTTDL
PANAKRKVLRRSAPKLLRADTVPGPLSLDDYCARPHALVSFAGDLSGFVDEELEKLGRKRHVVLAVPQFNGLGTLLAGTD
IVATVPDYTADALTAAGGLRAEDPPLPTRTFELHMAWRGSQDNDPGERWLRSRIQMFFGDPDSL
>Mature_304_residues
MNRNDLRRVDLNLLIVFETLMHERSVTRAAEKLFLGQPAISAALSRLRGLFDDPLFVRTGRSMEPSARAVEIFALLSPAL
DSISTAVSRAAEFDPATSTSVFRIGLSDDVEFALLPMLLKRLRAEAPGIVLVVRRVNYILMPGLLASGEISIGVSYTTDL
PANAKRKVLRRSAPKLLRADTVPGPLSLDDYCARPHALVSFAGDLSGFVDEELEKLGRKRHVVLAVPQFNGLGTLLAGTD
IVATVPDYTADALTAAGGLRAEDPPLPTRTFELHMAWRGSQDNDPGERWLRSRIQMFFGDPDSL

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=301, Percent_Identity=26.578073089701, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1790147, Length=308, Percent_Identity=25, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87081766, Length=126, Percent_Identity=31.7460317460317, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786820, Length=87, Percent_Identity=35.632183908046, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33248; Mature: 33248

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRNDLRRVDLNLLIVFETLMHERSVTRAAEKLFLGQPAISAALSRLRGLFDDPLFVRTG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECC
RSMEPSARAVEIFALLSPALDSISTAVSRAAEFDPATSTSVFRIGLSDDVEFALLPMLLK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHH
RLRAEAPGIVLVVRRVNYILMPGLLASGEISIGVSYTTDLPANAKRKVLRRSAPKLLRAD
HHHCCCCCEEEEEEHHCHHEECCEEECCCEEEEEEEECCCCCHHHHHHHHHCCCHHHHCC
TVPGPLSLDDYCARPHALVSFAGDLSGFVDEELEKLGRKRHVVLAVPQFNGLGTLLAGTD
CCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHCCCC
IVATVPDYTADALTAAGGLRAEDPPLPTRTFELHMAWRGSQDNDPGERWLRSRIQMFFGD
EEEECCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCC
PDSL
CCCC
>Mature Secondary Structure
MNRNDLRRVDLNLLIVFETLMHERSVTRAAEKLFLGQPAISAALSRLRGLFDDPLFVRTG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECC
RSMEPSARAVEIFALLSPALDSISTAVSRAAEFDPATSTSVFRIGLSDDVEFALLPMLLK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHH
RLRAEAPGIVLVVRRVNYILMPGLLASGEISIGVSYTTDLPANAKRKVLRRSAPKLLRAD
HHHCCCCCEEEEEEHHCHHEECCEEECCCEEEEEEEECCCCCHHHHHHHHHCCCHHHHCC
TVPGPLSLDDYCARPHALVSFAGDLSGFVDEELEKLGRKRHVVLAVPQFNGLGTLLAGTD
CCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHCCCC
IVATVPDYTADALTAAGGLRAEDPPLPTRTFELHMAWRGSQDNDPGERWLRSRIQMFFGD
EEEECCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCC
PDSL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]