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The map label for this gene is aaeR [H]

Identifier: 77458588

GI number: 77458588

Start: 2719391

End: 2720359

Strand: Reverse

Name: aaeR [H]

Synonym: Pfl01_2361

Alternate gene names: 77458588

Gene position: 2720359-2719391 (Counterclockwise)

Preceding gene: 77458593

Following gene: 77458587

Centisome position: 42.25

GC content: 64.91

Gene sequence:

>969_bases
TTGTATAGTTGGCGTCCCTTTTCCAGCGAATCTCGCCCCGTGCTAGACCTCAATGACCTGCAGTATTTCGTGATGGTGGT
GGACCACGGCGGCTTTGCGCCGACGGCGCGGGCGCTGGGGATTCCCAAATCGAACCTGAGCCGGCGCATTGCCTTGCTTG
AGGAGCGTCTGGGCGTGCGCCTGATCATCCGCAACACCCGGCACTTCTCGGTGACGGAGCTGGGCCAGACCTACTACGAC
CATTGCCGGGCGATGCTGAAACAGGCCGAGGCCGCCGAAGCCGCGATTGCCATGACCCGCGCCGAACCGGGCGGCGTGTT
GCGCGTGACCTGTCCGACGACGCTGCTGGAAGAATGCGTCGGCGGGATCATCACGCGCTTCATGGCCATGCACCCGCGCG
TCGAAATGCATCTGGAGGCCAGCGACCGGCAGGTCGACGTGGTGGCCGAAGGTGTCGATCTGGCGTTGCGGGTGCGGCCG
CCGCCCTTGCAGGATTCCGAGCTGGTCAGCCGGGTGCTGTCGCAGCGGCCGCAGTGCCTGGTCGCCAGCCCTGCGCTCTT
GAGCCGGCTGGGTGAACCGAGCGAGCCGGAAGACCTGTCGCGCTTCCCCAGCGCTCACCACGGCAGCCCGCAGCAGGTTT
ACAGCTGGACGCTGTTCCATCAGGACGGTTCCGAGTTCACCCTACAACATCGCCCGCAATTGATCACCAAAGGCCTGCCG
ATGCTGCGCTGCGCGGCCATCGACAGCGTCGGCGTTGCGCAGATGCCAATGTCGCTGGTGCATGACTTCATCGAACGCGG
CCAACTGGCGGTGGTGCTGCCCGACTGGGCGCCGCGTACGGAGATGATCTACGCGGTGTTTGCCAGCCGTCAGGGCATGC
TGCCGTCGCTGCGGATGCTGATCGACTTCATGGCCGAGCAGTTCGAGTTGCTGGACGATCCGCTGCGCGGAATGCGTACA
AAAGCCTGA

Upstream 100 bases:

>100_bases
AGTGTGTGCAAGGTTCGGACGGCGCAATCTACGGCTCGCCCGGCATCGCCCACCAGAGCCGAAAACGGGCCGCTGCTTCC
CACACAATGGACAATCGGGC

Downstream 100 bases:

>100_bases
GGCCATTACTCACAGTTCGTGTTTAACCGCTTCACCAATGCGCTCTTGATGGCATTTCTGCGATCAATATTCTGTCCTCA
TGTTGTTTTTGCCCCGGAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MYSWRPFSSESRPVLDLNDLQYFVMVVDHGGFAPTARALGIPKSNLSRRIALLEERLGVRLIIRNTRHFSVTELGQTYYD
HCRAMLKQAEAAEAAIAMTRAEPGGVLRVTCPTTLLEECVGGIITRFMAMHPRVEMHLEASDRQVDVVAEGVDLALRVRP
PPLQDSELVSRVLSQRPQCLVASPALLSRLGEPSEPEDLSRFPSAHHGSPQQVYSWTLFHQDGSEFTLQHRPQLITKGLP
MLRCAAIDSVGVAQMPMSLVHDFIERGQLAVVLPDWAPRTEMIYAVFASRQGMLPSLRMLIDFMAEQFELLDDPLRGMRT
KA

Sequences:

>Translated_322_residues
MYSWRPFSSESRPVLDLNDLQYFVMVVDHGGFAPTARALGIPKSNLSRRIALLEERLGVRLIIRNTRHFSVTELGQTYYD
HCRAMLKQAEAAEAAIAMTRAEPGGVLRVTCPTTLLEECVGGIITRFMAMHPRVEMHLEASDRQVDVVAEGVDLALRVRP
PPLQDSELVSRVLSQRPQCLVASPALLSRLGEPSEPEDLSRFPSAHHGSPQQVYSWTLFHQDGSEFTLQHRPQLITKGLP
MLRCAAIDSVGVAQMPMSLVHDFIERGQLAVVLPDWAPRTEMIYAVFASRQGMLPSLRMLIDFMAEQFELLDDPLRGMRT
KA
>Mature_322_residues
MYSWRPFSSESRPVLDLNDLQYFVMVVDHGGFAPTARALGIPKSNLSRRIALLEERLGVRLIIRNTRHFSVTELGQTYYD
HCRAMLKQAEAAEAAIAMTRAEPGGVLRVTCPTTLLEECVGGIITRFMAMHPRVEMHLEASDRQVDVVAEGVDLALRVRP
PPLQDSELVSRVLSQRPQCLVASPALLSRLGEPSEPEDLSRFPSAHHGSPQQVYSWTLFHQDGSEFTLQHRPQLITKGLP
MLRCAAIDSVGVAQMPMSLVHDFIERGQLAVVLPDWAPRTEMIYAVFASRQGMLPSLRMLIDFMAEQFELLDDPLRGMRT
KA

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=303, Percent_Identity=27.3927392739274, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=29.7945205479452, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=28.6689419795222, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=25, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI145693193, Length=298, Percent_Identity=24.1610738255034, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787128, Length=298, Percent_Identity=23.8255033557047, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=25.8620689655172, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789173, Length=292, Percent_Identity=27.3972602739726, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790208, Length=152, Percent_Identity=32.8947368421053, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788297, Length=82, Percent_Identity=37.8048780487805, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787601, Length=124, Percent_Identity=24.1935483870968, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI157672245, Length=120, Percent_Identity=30, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36083; Mature: 36083

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSWRPFSSESRPVLDLNDLQYFVMVVDHGGFAPTARALGIPKSNLSRRIALLEERLGVR
CCCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHCCEE
LIIRNTRHFSVTELGQTYYDHCRAMLKQAEAAEAAIAMTRAEPGGVLRVTCPTTLLEECV
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECHHHHHHHHH
GGIITRFMAMHPRVEMHLEASDRQVDVVAEGVDLALRVRPPPLQDSELVSRVLSQRPQCL
HHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCEE
VASPALLSRLGEPSEPEDLSRFPSAHHGSPQQVYSWTLFHQDGSEFTLQHRPQLITKGLP
EECHHHHHHCCCCCCCHHHHHCCCCCCCCCHHEEEEEEEECCCCCEEHHCCCHHHHCCCC
MLRCAAIDSVGVAQMPMSLVHDFIERGQLAVVLPDWAPRTEMIYAVFASRQGMLPSLRML
HHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHH
IDFMAEQFELLDDPLRGMRTKA
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYSWRPFSSESRPVLDLNDLQYFVMVVDHGGFAPTARALGIPKSNLSRRIALLEERLGVR
CCCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHCCEE
LIIRNTRHFSVTELGQTYYDHCRAMLKQAEAAEAAIAMTRAEPGGVLRVTCPTTLLEECV
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECHHHHHHHHH
GGIITRFMAMHPRVEMHLEASDRQVDVVAEGVDLALRVRPPPLQDSELVSRVLSQRPQCL
HHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCEE
VASPALLSRLGEPSEPEDLSRFPSAHHGSPQQVYSWTLFHQDGSEFTLQHRPQLITKGLP
EECHHHHHHCCCCCCCHHHHHCCCCCCCCCHHEEEEEEEECCCCCEEHHCCCHHHHCCCC
MLRCAAIDSVGVAQMPMSLVHDFIERGQLAVVLPDWAPRTEMIYAVFASRQGMLPSLRML
HHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHH
IDFMAEQFELLDDPLRGMRTKA
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]