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The map label for this gene is ycgM [H]

Identifier: 77458462

GI number: 77458462

Start: 2564786

End: 2565478

Strand: Reverse

Name: ycgM [H]

Synonym: Pfl01_2235

Alternate gene names: 77458462

Gene position: 2565478-2564786 (Counterclockwise)

Preceding gene: 77458463

Following gene: 77458461

Centisome position: 39.85

GC content: 64.07

Gene sequence:

>693_bases
ATGAACATGACCGAATACGTCTTTACCCCGGATCTGCCAGTGACCTTGCCGGTTGTCGGCAGCGAGCAACGCTTTCCCGT
CGGACGCGTGTTCTGCGTCGGCCGCAACTACCCGTGGCCGGACACCCTGGGCCAGCCGCGCCAGCCGCCGGTGTTCTTCA
TGAAACCGGCAAGCACTGTGGTGGACGCCGTCGGTGAAGTGACCTTCCCGTCACTGACCGAAGAGTTTGCCCATGAAATC
GAGCTGGTCGTGGCCATCGGCGAAGGCGGCGCGCAGATCCCCGAAAGCCAGGCGCTGGCCTATGTCTGGGGGTACGCCGC
CGGACTGGACCTGACCCGCCGTGACGTACAGCGCCTGGCCAAGCGCGACGGTTTGCCATGGGAAGGTGCCAAGGTGTTTG
ACGGCGCCGCACCGATGACCGCCATTGTGCCGGTCACTCGGACCGGTCGGCTCGAAGGGGAATTATGGTTGAGCGTGAAC
GGTGAAGAACGCCAGCGGGATCGACTCGACAGCCAGATCTGGTCGGTGAGTGAAGTCATCAGCCGCATCTCGCAATCCGT
CACACTCAAGGCCGGCGATCTGATCATGACCGGCAGCCCCGCCGGCGTCGATGTCTTGCAACCCGGCGACGTCATCAGCG
CCGGGATCGACGGCATTGGCCAACTCGAAATGCGCGTCGGCCCCCGGCCTTGA

Upstream 100 bases:

>100_bases
AAGCCAGAACAACCGGTTTCTCCAATTTGAGGCGGCTTTCGTCCAACTTCGCCAGCGATTGCCGCCGTACGCTTACCTTT
CACACAGGACTTGCAGCAGG

Downstream 100 bases:

>100_bases
ATCTGTCCTTAAGTGATTGAAAAAAGGAGAACAACAAAATGTCTGACACTCAATCCTTGAAAGTGGCCCTGGTGACCGGC
GCCGGCAGCGGGATCGGCCG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNMTEYVFTPDLPVTLPVVGSEQRFPVGRVFCVGRNYPWPDTLGQPRQPPVFFMKPASTVVDAVGEVTFPSLTEEFAHEI
ELVVAIGEGGAQIPESQALAYVWGYAAGLDLTRRDVQRLAKRDGLPWEGAKVFDGAAPMTAIVPVTRTGRLEGELWLSVN
GEERQRDRLDSQIWSVSEVISRISQSVTLKAGDLIMTGSPAGVDVLQPGDVISAGIDGIGQLEMRVGPRP

Sequences:

>Translated_230_residues
MNMTEYVFTPDLPVTLPVVGSEQRFPVGRVFCVGRNYPWPDTLGQPRQPPVFFMKPASTVVDAVGEVTFPSLTEEFAHEI
ELVVAIGEGGAQIPESQALAYVWGYAAGLDLTRRDVQRLAKRDGLPWEGAKVFDGAAPMTAIVPVTRTGRLEGELWLSVN
GEERQRDRLDSQIWSVSEVISRISQSVTLKAGDLIMTGSPAGVDVLQPGDVISAGIDGIGQLEMRVGPRP
>Mature_230_residues
MNMTEYVFTPDLPVTLPVVGSEQRFPVGRVFCVGRNYPWPDTLGQPRQPPVFFMKPASTVVDAVGEVTFPSLTEEFAHEI
ELVVAIGEGGAQIPESQALAYVWGYAAGLDLTRRDVQRLAKRDGLPWEGAKVFDGAAPMTAIVPVTRTGRLEGELWLSVN
GEERQRDRLDSQIWSVSEVISRISQSVTLKAGDLIMTGSPAGVDVLQPGDVISAGIDGIGQLEMRVGPRP

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=203, Percent_Identity=39.4088669950739, Blast_Score=147, Evalue=6e-36,
Organism=Homo sapiens, GI66348062, Length=198, Percent_Identity=40.4040404040404, Blast_Score=147, Evalue=9e-36,
Organism=Homo sapiens, GI215422413, Length=196, Percent_Identity=40.3061224489796, Blast_Score=145, Evalue=2e-35,
Organism=Homo sapiens, GI40786394, Length=211, Percent_Identity=32.2274881516588, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI156231349, Length=211, Percent_Identity=32.2274881516588, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1787428, Length=203, Percent_Identity=38.9162561576355, Blast_Score=132, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17557057, Length=193, Percent_Identity=36.7875647668394, Blast_Score=126, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6324161, Length=242, Percent_Identity=29.7520661157025, Blast_Score=105, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28571789, Length=195, Percent_Identity=33.8461538461538, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28572127, Length=216, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24663695, Length=194, Percent_Identity=29.3814432989691, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 24960; Mature: 24960

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMTEYVFTPDLPVTLPVVGSEQRFPVGRVFCVGRNYPWPDTLGQPRQPPVFFMKPASTV
CCCCCEEECCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCHHHH
VDAVGEVTFPSLTEEFAHEIELVVAIGEGGAQIPESQALAYVWGYAAGLDLTRRDVQRLA
HHHHCCCCCHHHHHHHHHEEEEEEEECCCCCCCCCCHHHEEEEHHHCCCCHHHHHHHHHH
KRDGLPWEGAKVFDGAAPMTAIVPVTRTGRLEGELWLSVNGEERQRDRLDSQIWSVSEVI
HHCCCCCCCCEEECCCCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
SRISQSVTLKAGDLIMTGSPAGVDVLQPGDVISAGIDGIGQLEMRVGPRP
HHHHHCEEEEECCEEEECCCCCCEEECCCCHHHHCCCCCEEEEEEECCCC
>Mature Secondary Structure
MNMTEYVFTPDLPVTLPVVGSEQRFPVGRVFCVGRNYPWPDTLGQPRQPPVFFMKPASTV
CCCCCEEECCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCHHHH
VDAVGEVTFPSLTEEFAHEIELVVAIGEGGAQIPESQALAYVWGYAAGLDLTRRDVQRLA
HHHHCCCCCHHHHHHHHHEEEEEEEECCCCCCCCCCHHHEEEEHHHCCCCHHHHHHHHHH
KRDGLPWEGAKVFDGAAPMTAIVPVTRTGRLEGELWLSVNGEERQRDRLDSQIWSVSEVI
HHCCCCCCCCEEECCCCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
SRISQSVTLKAGDLIMTGSPAGVDVLQPGDVISAGIDGIGQLEMRVGPRP
HHHHHCEEEEECCEEEECCCCCCEEECCCCHHHHCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]