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The map label for this gene is fhuA [H]

Identifier: 77458459

GI number: 77458459

Start: 2560811

End: 2562937

Strand: Direct

Name: fhuA [H]

Synonym: Pfl01_2232

Alternate gene names: 77458459

Gene position: 2560811-2562937 (Clockwise)

Preceding gene: 77458458

Following gene: 77458464

Centisome position: 39.77

GC content: 60.79

Gene sequence:

>2127_bases
ATGCGTCGAACTCTGCTGTCCATCTGCGTGTTGCAAACGTTGTCTCCCTTGGCGTGGGCCGAGCCATCCGATTCAACGGT
GTCAGCGCTGGAGCTGGAGGCAACCGATGTGGTCGGTACCGCGGATTACGAAAGAGCGGACGGCCCGGTACAGGGATATC
GCGCGACCCGTTCGGCCAGCGCTACCCGAACCGATACCTCGATCCATGAAACCCCGCAGTCGATCAGCGTCGTCACCAAA
GATGCGGTCGAAGACATCGGTGCTACCCGGCTGCAGGACGCACTGGATTACGCGGGCGGAGTAGGGCGAGCCAACAATTT
CGGCGGCCAGGGACTGACCACGTTCACCGTGCGCGGATTTACCACTGGCGAGTTCTACCGCAATGGTTTCCCGATCAACC
GCGGTTATCCGAACATGCCGGATGCCAACACCATCGAGCGACTTGAGGTCCTGCGCGGTCCGGCGACCATGCTCTACGGC
CGGGGCGATCCGGGCGGTACCTTCAATGTCGTTTCCAAACAACCGTTGCCCGAGCGTACGGTCACACTCGGCAGCCAGCT
GAATGACCAAGGCATGCGCCGCGGCACCCTGGATGCTTCCGGTCCGCTCGATGAAGAGGGGCGTCTGGCCTATCGCCTGA
ACGTGGTGGGCGAGGGCGGCGATACCTTCCGCGATCACGTCGAAACCGAACGCTACGGCGTGACCCCCGTGCTGACCTGG
CAAGCCAGCGATGACACCCGAGTGATCTTCGAGGGTGACTTCATGCGCAACAACCATCCGCTGGACCGGGGCGCGACGCG
TTATCCCCGGCAGATCGGCACTGCCTCCCGCGACACCTTCTTCGGTGAACCGGACGCTGGCAAGTTGCACAACGACAACA
ACATGGCGCAATTGCGCTTCGAGCATGTGCTCAATGAGGACTGGACGCTCGGCGGTGGCTTCCAGTGGCTCGACGGTACC
TTGCAGGGCAATGCCATTGAAGCCAACGGCATTGCCGCCGACGGCCGGACTCTGGGACGAAATTTCAACTACCGCAAGCT
GGAGTGGACGGACAAGGACACCCAACTCAACCTGACCGGTCACTTCTCCACCGGCGGCCTGCAGCACACATTGCTGACCG
GTATCGAATACGAAGATTACGACTACCAGTCGATCATCCAGCGCTCCAGCGGCGCGGTGAGTGCCTATCCGATCGATATC
TTCAATCCGGTCTATGGGCAGCCCCGTCCGGCACTGACACGCACCCCGACCCACGACAAGGAAAACCTCAAGACCTACGC
CGCGTTCGTACAGGACCAGGTGGCCCTGACCGATCGGCTGAAAGTCCTGGCCGGGGCACGTTTTGAACGCTTTGAACACG
ACTACGAAACCTACGTGCCCGGCGGCAAGAACTGGCAGGCCAGTGACAATGCCGTCACGCCCCGCGTCGGTGTGACCTAT
GACCTAACCGACACCCTCGCGATTTACGCGGACACCGCGCGTTCCTTCAAGCCCAATACCGGCGCAAGCCGACAGGGCGG
CGGCTTCGAACCGGAGAAAGGCAAGTCCTGGGAGATGGGCGTCAAATGGGAAGCGCTGGATCATCAGCTGAGCGTTGACG
CGGCGATCTATCAGATTGAAAAGCGCAATGTCCTGACCACTGACCCGGTGGACTCGACGTTCAGCGTGGCTGCCGGGGAA
GTGCGCAGCCGGGGATTCGACCTCAATGTCGCCGGCAACCTGACCCCCGAGTGGCGTGTCATCGGGGGGTACGCCTACGT
CGATGCCGAGGTGACCAAGGACAACGTGATCCGCTCCGGCACGCGACTGATGAACATCCCGAAAAACAGCTTCAGCCTGC
TCAACGTCTATGAGTTCCAGGACGGTGCCCTCAGTGGTCTGGGTCTGGGGACAGGCGTCAAATATGTCGATGAGCGCGCG
GGTCAAACGGCCAACACTGCATTTTCGATGGGGAGCTACACCGTTGTCGACCTGCTCAGCTACTACAAGGTCAATGACAA
GTTACGTCTCAATCTCGACCTGAAGAACCTGTTTGACCGGGACTACGACGAGGGCGCATTCGGTAACGTCTACGCCTATC
CGGGGGCACCGAGAACGGTGCAGGTCGGCATTTCCTACACGTTGTAG

Upstream 100 bases:

>100_bases
TGGGAATGCCTATCAATTGCGCGGCGGGTGGTATACCATCCGCCGCGTTTCGCTGGCAGTTATCCCCTTCGTTCTGGCTT
ATCCGTAAGGTTCTCCCCTC

Downstream 100 bases:

>100_bases
TCCGATCGGGTCTGAAATCCATCATCGGGGGCAGCGGCCCCCGATGACTGTGAGGCTCAGCCGGTCACACATCCTTGCGG
AGTCTTTCCGGCAAAACTGT

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 708; Mature: 708

Protein sequence:

>708_residues
MRRTLLSICVLQTLSPLAWAEPSDSTVSALELEATDVVGTADYERADGPVQGYRATRSASATRTDTSIHETPQSISVVTK
DAVEDIGATRLQDALDYAGGVGRANNFGGQGLTTFTVRGFTTGEFYRNGFPINRGYPNMPDANTIERLEVLRGPATMLYG
RGDPGGTFNVVSKQPLPERTVTLGSQLNDQGMRRGTLDASGPLDEEGRLAYRLNVVGEGGDTFRDHVETERYGVTPVLTW
QASDDTRVIFEGDFMRNNHPLDRGATRYPRQIGTASRDTFFGEPDAGKLHNDNNMAQLRFEHVLNEDWTLGGGFQWLDGT
LQGNAIEANGIAADGRTLGRNFNYRKLEWTDKDTQLNLTGHFSTGGLQHTLLTGIEYEDYDYQSIIQRSSGAVSAYPIDI
FNPVYGQPRPALTRTPTHDKENLKTYAAFVQDQVALTDRLKVLAGARFERFEHDYETYVPGGKNWQASDNAVTPRVGVTY
DLTDTLAIYADTARSFKPNTGASRQGGGFEPEKGKSWEMGVKWEALDHQLSVDAAIYQIEKRNVLTTDPVDSTFSVAAGE
VRSRGFDLNVAGNLTPEWRVIGGYAYVDAEVTKDNVIRSGTRLMNIPKNSFSLLNVYEFQDGALSGLGLGTGVKYVDERA
GQTANTAFSMGSYTVVDLLSYYKVNDKLRLNLDLKNLFDRDYDEGAFGNVYAYPGAPRTVQVGISYTL

Sequences:

>Translated_708_residues
MRRTLLSICVLQTLSPLAWAEPSDSTVSALELEATDVVGTADYERADGPVQGYRATRSASATRTDTSIHETPQSISVVTK
DAVEDIGATRLQDALDYAGGVGRANNFGGQGLTTFTVRGFTTGEFYRNGFPINRGYPNMPDANTIERLEVLRGPATMLYG
RGDPGGTFNVVSKQPLPERTVTLGSQLNDQGMRRGTLDASGPLDEEGRLAYRLNVVGEGGDTFRDHVETERYGVTPVLTW
QASDDTRVIFEGDFMRNNHPLDRGATRYPRQIGTASRDTFFGEPDAGKLHNDNNMAQLRFEHVLNEDWTLGGGFQWLDGT
LQGNAIEANGIAADGRTLGRNFNYRKLEWTDKDTQLNLTGHFSTGGLQHTLLTGIEYEDYDYQSIIQRSSGAVSAYPIDI
FNPVYGQPRPALTRTPTHDKENLKTYAAFVQDQVALTDRLKVLAGARFERFEHDYETYVPGGKNWQASDNAVTPRVGVTY
DLTDTLAIYADTARSFKPNTGASRQGGGFEPEKGKSWEMGVKWEALDHQLSVDAAIYQIEKRNVLTTDPVDSTFSVAAGE
VRSRGFDLNVAGNLTPEWRVIGGYAYVDAEVTKDNVIRSGTRLMNIPKNSFSLLNVYEFQDGALSGLGLGTGVKYVDERA
GQTANTAFSMGSYTVVDLLSYYKVNDKLRLNLDLKNLFDRDYDEGAFGNVYAYPGAPRTVQVGISYTL
>Mature_708_residues
MRRTLLSICVLQTLSPLAWAEPSDSTVSALELEATDVVGTADYERADGPVQGYRATRSASATRTDTSIHETPQSISVVTK
DAVEDIGATRLQDALDYAGGVGRANNFGGQGLTTFTVRGFTTGEFYRNGFPINRGYPNMPDANTIERLEVLRGPATMLYG
RGDPGGTFNVVSKQPLPERTVTLGSQLNDQGMRRGTLDASGPLDEEGRLAYRLNVVGEGGDTFRDHVETERYGVTPVLTW
QASDDTRVIFEGDFMRNNHPLDRGATRYPRQIGTASRDTFFGEPDAGKLHNDNNMAQLRFEHVLNEDWTLGGGFQWLDGT
LQGNAIEANGIAADGRTLGRNFNYRKLEWTDKDTQLNLTGHFSTGGLQHTLLTGIEYEDYDYQSIIQRSSGAVSAYPIDI
FNPVYGQPRPALTRTPTHDKENLKTYAAFVQDQVALTDRLKVLAGARFERFEHDYETYVPGGKNWQASDNAVTPRVGVTY
DLTDTLAIYADTARSFKPNTGASRQGGGFEPEKGKSWEMGVKWEALDHQLSVDAAIYQIEKRNVLTTDPVDSTFSVAAGE
VRSRGFDLNVAGNLTPEWRVIGGYAYVDAEVTKDNVIRSGTRLMNIPKNSFSLLNVYEFQDGALSGLGLGTGVKYVDERA
GQTANTAFSMGSYTVVDLLSYYKVNDKLRLNLDLKNLFDRDYDEGAFGNVYAYPGAPRTVQVGISYTL

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=744, Percent_Identity=29.9731182795699, Blast_Score=265, Evalue=1e-71,
Organism=Escherichia coli, GI1787024, Length=705, Percent_Identity=26.9503546099291, Blast_Score=198, Evalue=8e-52,
Organism=Escherichia coli, GI1787344, Length=755, Percent_Identity=23.1788079470199, Blast_Score=146, Evalue=5e-36,
Organism=Escherichia coli, GI1787723, Length=683, Percent_Identity=23.5724743777452, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1790743, Length=302, Percent_Identity=26.4900662251656, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 77938; Mature: 77938

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTLLSICVLQTLSPLAWAEPSDSTVSALELEATDVVGTADYERADGPVQGYRATRSAS
CCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECEEEECCCCCCCCCCCCCHHHHCCCC
ATRTDTSIHETPQSISVVTKDAVEDIGATRLQDALDYAGGVGRANNFGGQGLTTFTVRGF
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECC
TTGEFYRNGFPINRGYPNMPDANTIERLEVLRGPATMLYGRGDPGGTFNVVSKQPLPERT
CCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCHHH
VTLGSQLNDQGMRRGTLDASGPLDEEGRLAYRLNVVGEGGDTFRDHVETERYGVTPVLTW
HHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCEEEEE
QASDDTRVIFEGDFMRNNHPLDRGATRYPRQIGTASRDTFFGEPDAGKLHNDNNMAQLRF
ECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHEEEH
EHVLNEDWTLGGGFQWLDGTLQGNAIEANGIAADGRTLGRNFNYRKLEWTDKDTQLNLTG
HHHCCCCCEECCCCEEECCEECCCEEECCCEECCCHHHCCCCCEEEEEECCCCCEEEEEE
HFSTGGLQHTLLTGIEYEDYDYQSIIQRSSGAVSAYPIDIFNPVYGQPRPALTRTPTHDK
ECCCCCCCCHHCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCH
ENLKTYAAFVQDQVALTDRLKVLAGARFERFEHDYETYVPGGKNWQASDNAVTPRVGVTY
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCEEE
DLTDTLAIYADTARSFKPNTGASRQGGGFEPEKGKSWEMGVKWEALDHQLSVDAAIYQIE
ECCCCEEEEECCHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCEEEEEEE
KRNVLTTDPVDSTFSVAAGEVRSRGFDLNVAGNLTPEWRVIGGYAYVDAEVTKDNVIRSG
CCCEEECCCCCCCHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEEEEEEECCCCHHHHCC
TRLMNIPKNSFSLLNVYEFQDGALSGLGLGTGVKYVDERAGQTANTAFSMGSYTVVDLLS
CEEEECCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCEEECCCHHHHHHHH
YYKVNDKLRLNLDLKNLFDRDYDEGAFGNVYAYPGAPRTVQVGISYTL
HHCCCCEEEEEEEHHHHHCCCCCCCCCCCEEECCCCCCEEEEEEEECC
>Mature Secondary Structure
MRRTLLSICVLQTLSPLAWAEPSDSTVSALELEATDVVGTADYERADGPVQGYRATRSAS
CCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECEEEECCCCCCCCCCCCCHHHHCCCC
ATRTDTSIHETPQSISVVTKDAVEDIGATRLQDALDYAGGVGRANNFGGQGLTTFTVRGF
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECC
TTGEFYRNGFPINRGYPNMPDANTIERLEVLRGPATMLYGRGDPGGTFNVVSKQPLPERT
CCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCHHH
VTLGSQLNDQGMRRGTLDASGPLDEEGRLAYRLNVVGEGGDTFRDHVETERYGVTPVLTW
HHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCEEEEE
QASDDTRVIFEGDFMRNNHPLDRGATRYPRQIGTASRDTFFGEPDAGKLHNDNNMAQLRF
ECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHEEEH
EHVLNEDWTLGGGFQWLDGTLQGNAIEANGIAADGRTLGRNFNYRKLEWTDKDTQLNLTG
HHHCCCCCEECCCCEEECCEECCCEEECCCEECCCHHHCCCCCEEEEEECCCCCEEEEEE
HFSTGGLQHTLLTGIEYEDYDYQSIIQRSSGAVSAYPIDIFNPVYGQPRPALTRTPTHDK
ECCCCCCCCHHCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCH
ENLKTYAAFVQDQVALTDRLKVLAGARFERFEHDYETYVPGGKNWQASDNAVTPRVGVTY
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCEEE
DLTDTLAIYADTARSFKPNTGASRQGGGFEPEKGKSWEMGVKWEALDHQLSVDAAIYQIE
ECCCCEEEEECCHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCEEEEEEE
KRNVLTTDPVDSTFSVAAGEVRSRGFDLNVAGNLTPEWRVIGGYAYVDAEVTKDNVIRSG
CCCEEECCCCCCCHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEEEEEEECCCCHHHHCC
TRLMNIPKNSFSLLNVYEFQDGALSGLGLGTGVKYVDERAGQTANTAFSMGSYTVVDLLS
CEEEECCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCEEECCCHHHHHHHH
YYKVNDKLRLNLDLKNLFDRDYDEGAFGNVYAYPGAPRTVQVGISYTL
HHCCCCEEEEEEEHHHHHCCCCCCCCCCCEEECCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]